$5190
$4671
The amniotic membrane market is expected to reach US$ 2,808.39 million by 2028 from US$ 1,827.85 million in 2022, growing at a CAGR of 7.4% from 2022 to 2028.
The report highlights trends prevailing in the market and factors driving its growth. The market's growth is attributed to the rising use of amniotic membranes in eye surgeries. However, the breakdown of membranes is hindering the growth of the global amniotic membrane market.
North America held the largest market for amniotic membrane, with the US holding the largest share of the regional market, followed by Canada and Mexico. The US held the largest share in 2019 and is expected to follow a similar trend during the forecast period. According to the American academy of Ophthalmology, there were 718 thousand surgeries that occurred yearly in 2020 in the US. According to the American academy of Ophthalmology, glaucoma affected more than 2.7 million Americans aged 40 and above in 2020. Amniotic membrane is widely used in eye surgery as a biological bandage to heal the damaged eye tissue. It is thin, lightweight, elastic and almost transparent in nature making it suitable for use on the surface of the eye. It can be sutured or glued into place with tissue glue. Amniotic membrane is used to treat chemical burns, ulcers of the cornea or conjunctiva, diseases causing devastating ulcerations and during surgical procedures where eye tissue has to be excised. For instance, amniotic membrane is used successfully in Pterygium surgery procedure which is commonly performed in both developed and developing economies. Pterygium is a benign growth on the conjunctiva of the eye, usually in the area closest to the nose. These growths can cause irritation in the eye and need to be removed surgically. The deficit left after the removal is successfully healed with amniotic membrane placements. Some other applications wherein amniotic membranes are used increasingly are ulcers, burns, wounds, and animal bites.
Strategic Insights
Amniotic membrane therapy is an option for those who are at risk of limb amputation. An amniotic membrane is a sustainable and powerful option, especially with new preservation techniques that allow them to be available across various clinical settings such as hospitals, clinics, specialty clinics, and ambulatory surgical centers.
Applied Biologics LLC; Integra Life Sciences Corporation; Skye Biologics Inc.; MiMedx; Organogenesis Inc.; Smith & Nephew; Amniox Medical, Inc.; Katena Products, Inc.; Amnio technology, LLC.; and Surgenex, LLC are among the leading companies in the global amniotic membrane market. The market is anticipated to flourish with the development of new innovative products by market players.
- In November 2022, it has been reported by the Journal of Biomaterials Applications that human amniotic membrane or amnion can resolve some bottlenecks in the regenerative medicine issues such as tissue engineering and cell therapy. In the recent past, biomedical applications of amnion have evolved from a simple sheet for skin or cornea repair to high-technology applications such as amnion nanocomposite, powder, or hydrogel for the regeneration of cartilage, muscle, tendon, and heart. Thus, new applications of amnion in research and clinical applications, from regenerative medicine to cancer therapy is expected to aid the overall amniotic membrane market growth during the forecast period.
- In August 2022, CryoTek CAM launched Amniograft, the only graft used for eye transplant application. Amniograft’s cryopreservation method maintains all the biological components of the tissue, such as heavy chain hyaluronic acid (HCHA) and pentraxin 3 (PTX3), which help to rapidly restore the healing capabilities of the ocular surface. The product is widely used for conjunctivochalase (CCH)also known as mechanical dry eye (MDE)
Lucrative Regions for Amniotic Membrane Market
Enzyme Insights
Based on enzyme, the global amniotic membrane market is divided intocryopreserved amniotic membrane and dehydrated amniotic membrane. Cropreserved amniotic membrane segment captured the largest share in 2019 and is expected to continue a similar trend during the forecast period. Cryopreservation was first introduced by Lee and Tseng and has been proven to achieve high success rate in amniotic membrane transplantation and has been distinguished from many other types of methods for its advantages such as prolonging use span, optimally retaining tissue structure, and minimizing infection risk. On the other hand, dehydrated amniotic membrane is expected to witness the highest growth during the forecast period owing to its increasing shelf-life.
Application Insights
Based on application, the amniotic membrane market has been segmented into surgical wounds, ophthalmology, and others. The surgical wounds captured the largest share in 2019 and is expected to continue a similar trend during the forecast period. Owing to the presence of large number of cytokines and essential growth factors, amniotic membrane is an ideal option for treating surgical wounds. The also enhances the wound healing process.
End User Insights
Based on end user, the amniotic membrane market is segmented into hospitals, ambulatory surgical centers, specialty clinics, and academic & research institutes. In 2019, the hospitals segment held the largest share of amniotic membrane market and is expected to continue a similar trend during the forecast period. The adoption of new technology methods by hospitals across the globe has resulted in the growth of overall industry. Amniotic membrane therapy is an option for those who are at risk of limb amputation. An amniotic membrane is a sustainable and powerful option, especially with new preservation techniques that allow them to be available across various clinical settings such as hospitals, clinics, specialty clinics, and ambulatory surgical centers.
Companies operating in the amniotic membrane market are adopting the product innovation strategy to meet the evolving customer demands worldwide, allowing them to maintain their brand name in the global amniotic membrane market.
The report segments the amniotic membrane market as follows:
The amniotic membrane market is bifurcated into enzyme, application, end user, and geography. Based on enzyme, the global amniotic membrane market is divided intocryopreserved amniotic membrane and dehydrated amniotic membrane. Based on application, the amniotic membrane market has been segmented into surgical wounds, ophthalmology, and others. Based on end user, the amniotic membrane market is segmented into hospitals, ambulatory surgical centers, specialty clinics, and academic & research institutes. Based on geography, the amniotic membrane market is segmented into North America (the US, Canada, and Mexico), Europe (the UK, Germany, France, Italy, Spain, and the Rest of Europe), Asia Pacific (China, Japan, India, Australia, South Korea, and the Rest of Asia Pacific), the Middle East & Africa (the UAE, Saudi Arabia, South Africa, and the Rest of the Middle East & Africa), and South & Central America (Brazil, Argentina, and the Rest of South & Central America).
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Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Enzyme, Application, and End User
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States
Frequently Asked Questions
Amniotic membrane is a combination of tissues and cells that helps heal the wound by acting as a foundation for regrowth of the soft tissues. It is an avascular fetal membrane-derived from placental tissue and is used to treat certain types of conjunctival and corneal disease. The technological development has allowed using amniotic membrane in eye surgery as a biological bandage to heal or replace damaged eye tissue. Also, it widely used in advanced wound care. It shows several properties such as antimicrobial, anti-inflammatory, anti-scarring, and anti-adhesive, among others.
The growth of market is likely to grow due to factors such as growing applications of amniotic membrane and rising number of target patient population. However, challenges in using amniotic membranes are likely to restraint the market growth during the forecast period.
The average cost of an amniotic membrane may vary between U$ 250 and US$ 1000 per membrane. The cost is much higher, and therefore, in various countries, the cost is reimbursed through the health insurance policies.
The List of Companies - Amniotic Membrane Market
- Applied Biologics LLC
- Integra Life Sciences Corporation
- Skye Biologics Inc.
- MiMedx
- Organogenesis Inc.
- Smith & Nephew
- Amniox Medical, Inc.
- Katena Products. Inc.
- Amnio Technology, LLC
- Surgenex, LLC
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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