Epinephrine Market Size, Share & Growth Analysis Report To 2027

Epinephrine Market to 2027 - Global Analysis and Forecasts By Product Type (Prefilled Syringes, Auto-Injectors, Ampoules and Vials); Application (Anaphylaxis, Superficial Bleeding, Respiratory Disorders, Cardiac Arrest); Distribution Channel (Retail Pharmacies, Hospital Pharmacies, Online Pharmacies); and Geography

Publication Month : Feb 2020

  • Report Code : TIPRE00003412
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 144
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[Research Report] The epinephrine market was valued at US$ 2,247.87  million in 2018 and it is projected to reach US$  4,207.88 million by 2027; it is expected to grow at a CAGR of 8.3% from 2019 to 2027.

Epinephrine is a medication used along with emergency medical treatment services for the allergic reactions caused by insect bites or stings, foods, drugs, and latex, among others. It works by relaxing the muscles in the airways and tightening the blood vessels. The injection is available as a prefilled automatic injection device that contains the solution and in vials to inject subcutaneously and others. The injection is generally injected as required at the first sign of a severe allergic reaction. The growth of the Epinephrine market is attributed to the increasing anaphylaxis cases and introduction of generic version of epinephrine are expected to boost the market growth over the years. However, lack of availability of epinephrine auto injectors and their low-cost alternatives is likely to have a negative impact on the growth of the market in the coming years.

Report Coverage

The Epinephrine market is expected to witness substantial growth post-pandemic. The COVID-19 has affected economies and industries in various countries due to lockdowns, travel bans, and business shutdowns. The COVID-19 crisis has overburdened public health systems in many countries and highlighted the strong need for sustainable investment in health systems. As the COVID-19 pandemic progresses, the healthcare industry is expected to see a drop in growth. The life sciences segment thrives due to increased demand for invitro diagnostic products and rising research and development activities worldwide. However, the medical technologies and imaging segment is witnessing drop in sales due to a smaller number of surgeries being carried out and delayed or prolonged equipment procurement. Additionally, virtual consultations by healthcare professionals are expected to become the mainstream care delivery model post-pandemic. With telehealth transforming care delivery, digital health will continue to thrive in coming years. In addition, disrupted clinical trials and the subsequent delay in drug launches is also expected to pave the way for entirely virtual trials in the future. New technologies such as mRNA is expected to emerge and shift the pharmaceutical industry and market is also expected to witness more vertical integration and joint ventures in coming years.

Lucrative Regions for Epinephrine Market

Lucrative Regions for Epinephrine in Healthcare Market
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Market Insights

Growing Applications of Epinephrine in Healthcare to Drive Epinephrine Market Growth

Anaphylaxis is a severe, life

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threatening allergic reaction characterized by symptoms such as skin redness and itching, swallowing and breathing difficulties, wheezing, rapid breathing rate (tachypnoea), accelerated heart rate (tachycardia), and falling blood pressure. It may involve multiple systems of human body. Anaphylaxis is caused by exposure to an allergen (foods, insect stings, or medicines) that is recognized as a non-self by a human body. 

The incidence of anaphylaxis is increasing worldwide; according to the NICE, the UK registers an estimated death count of 20 due to anaphylaxis, every year. Moreover, as per the European Academy of Allergy and Clinical Immunology data, ~150 million Europeans suffer from chronic allergic diseases, every year. Anaphylaxis is a generalized allergic reaction; thus the rising incidence of allergies is also leading to the surge in the number of anaphylaxis cases. A large population suffers from various allergies worldwide. For example, as per Allergy Facts by the American College of Allergy, Asthma & Immunology, more than 50 million Americans experience different types of allergies every year. Moreover, it also lists allergies as the sixth-leading cause of chronic illness in the US and the most common health issues in children. In 2015, 8.2% of adults and 8.4% of children were diagnosed with hay fever. According to the Asthma and Allergy Foundation of America, in the last few years, hospital visits have also increased due to food allergic reaction. According to Food Allergy Research & Education, ~32 million Americans are living with life-threatening food allergies, and there are 200,000 visits to the emergency room every year due to food allergies. Allergies put an economic burden on healthcare systems in many countries; for example, according to Allergy Facts, the annual cost of managing the cases of allergies is more than USD 18 billion in the US. Anaphylaxis requires immediate medical treatment, and it can turn lethal if not treated properly. ~90–100 Americans die every year due to anaphylaxis caused by insect stings. 

Epinephrine is the first-line treatment in anaphylaxis cases. As per studies, it prevents or reduces upper airway mucosal edema, i.e., laryngeal edema, hypotension, and shock through vasoconstrictor effects. Additionally, it has important bronchodilator effects and cardiac inotropic as well as chronotropic effects. Thus, the increasing anaphylactic incidences is driving the growth of the market.

Epinephrine is the most effective treatment for anaphylaxis; however, various studies indicate underutilization of this drug due to high cost, lack of availability, unawareness regarding usage procedure and anaphylactic onset, etc. With steep price hike over the past decade, the lack of affordable alternatives have caused trouble for the patient to access this drug. EpiPen is an injection device that dispenses epinephrine, and people with severe allergies have been relying on it in case of life-threatening allergic reactions. Epinephrine alone is a generic drug, but the EpiPen is a drug-device combination product, which makes it difficult to replicate and get FDA approval for competitors. Therefore, there has been a limited number of players in this space. Moreover, the demand for epinephrine has been on the rise with limited product supply. As per the Pew Charitable Trusts, demand for epinephrine auto-injectors has increased in the last few years, and the number of EpiPen prescriptions in the US grew from ~2.5 million in 2011 to 3.5 million in 2015. The growth can be attributed to the high demand from schools. 

Mylan has been a dominant players in the epinephrine auto-injector market since long. However, in 2018, Teva Pharmaceutical received the generic version FDA approval for its epinephrine auto-injector. This approval is the first generic version of the most widely prescribed epinephrine auto-injector in the US. It is expected to advance access to lower cost, safe, and effective generic alternatives in the future. Patients usually don't have enough choice in medication for such life-threatening conditions; however, as more generics enter the market, providers and patients have more choices.

Product Type-Based Insights

In terms of product type, the Epinephrine market is segmented into prefilled syringes, auto-injectors, ampoules and vials. The auto-injectors segment held the largest share of the market in 2019. The auto-injectors segment is also anticipated to register the highest CAGR of 8.6% in the market during the forecast period.

Epinephrine Market, by Product Type – 2018 and 2027

Epinephrine in Healthcare Market, by Product Type – 2018 and 2027
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Application-Based Insights

Based on application, the Epinephrine market is segmented into anaphylaxis, superficial bleeding, respiratory disorders, cardiac arrest. The anaphylaxis segment held the largest share of the market in 2019. Anaphylaxis segment is also estimated to register the highest CAGR of 8.9% in the market during the forecast period

Distribution Channel-Based Insights

In terms of distribution channel, the Epinephrine market is segmented into retail pharmacies, hospital pharmacies, online pharmacies. The retail pharmacies segment held the largest share of the market in 2019. Retail pharmacies segment is also estimated to register the highest CAGR of 8.9% in the market during the forecast period.

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Epinephrine Market: Strategic Insights

epinephrine-market
Market Size Value inUS$ 2,247.87 Million in 2018
Market Size Value byUS$ 4,207.88 Million by 2027
Growth rateCAGR of 8.3% from 2019-2027
Forecast Period2019-2027
Base Year2019
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The Epinephrine market players are adopting the product launch and expansion strategies to cater to changing customer demands worldwide, which also allows them to maintain their brand name globally.

Epinephrine Market – by Product Type

  • Prefilled Syringes
  • Auto-Injectors
  • Ampoules and Vials

Epinephrine Market – by Application

  • Anaphylaxis
  • Superficial Bleeding
  • Respiratory Disorders
  • Cardiac Arrest

Epinephrine Market – by Distribution Channel

  • Retail Pharmacies
  • Hospital Pharmacies
  • Online Pharmacies

Epinephrine Market – by Geography

  • North America
    • US
    • Canada
    • Mexico
  • Europe
    • France
    • Germany
    • Italy
    • UK
    • Spain
    • Rest of Europe
  • Asia Pacific (APAC)
    • China
    • India
    • South Korea
    • Japan
    • Australia
    • Rest of APAC
  • Middle East & Africa (MEA)
    • South Africa
    • Saudi Arabia
    • UAE
    • Rest of MEA
  • South America and Central America (SCAM)
    • Brazil
    • Argentina
    • Rest of SCAM

Company Profiles

  • MYLAN N.V.
  • Abbott
  • ALK ABELLO
  • Amneal Pharma
  • Kaleo
  • LINCOLN MEDICAL LTD (BioProject)
  • Teva Pharmaceuticals Ltd
  • Adamis Pharmaceuticals Corporation (Novartis AG)
  • Emirade
  • Aurum Pharma
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Product Type ; Application ; Distribution Channel ; and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions


What is epinephrine?

Epinephrine is a medication used along with emergency medical treatment services for the allergic reactions caused by insect bites or stings, foods, drugs, and latex, among others. It works by relaxing the muscles in the airways and tightening the blood vessels. The injection is available as a prefilled automatic injection device that contains the solution and in vials to inject subcutaneously and others. The injection is generally injected as required at the first sign of a severe allergic reaction

What are the driving factors for the epinephrine market across the globe?

The key factor that are responsible for the growth of market include increasing anaphylaxis cases and introduction of generic version of epinephrine. However, lack of availability of epinephrine auto injectors and their low-cost alternatives is likely to have a negative impact on the growth of the market in the coming years.

What is the average cost of epinephrine?

The average cost of an epinephrine auto-injector is approximately US$130 - US$150. It is an emergency medicine used to treat severe allergic reactions. The drug is available in both innovative and generic brand. Thus, the cost of the drug may vary accordingly.

The List of Companies - Epinephrine Market

  1. MYLAN N.V
  2. Abbott
  3. ALK ABELLO
  4. Amneal Pharma
  5. Kaleo
  6. LINCOLN MEDICAL LTD (BioProject)
  7. Teva Pharmaceuticals Ltd
  8. Adamis Pharmaceuticals Corporation (Novartis AG)
  9. Emirade
  10. Aurum Pharma (Ethypharm Group Company).

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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