基于(关键地区、市场参与者、规模和份额)的抗体发现市场 - 到 2030 年的预测

  • Report Code : TIPRE00007411
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 180
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【研究报告】抗体发现市场规模预计将从2022年的29.4亿美元激增至2030年的49.2亿美元;预计 2022 年至 2030 年市场复合年增长率为 6.7%。

分析师观点:

该报告包括由于当前抗体发现市场趋势及其可预见的影响而产生的增长前景预测期。全球慢性病患病率不断上升以及个性化医疗需求不断增长等因素推动了抗体药物发现市场的增长。老年人群是癌症、自身免疫性疾病和传染病等慢性病的高危人群,这反映出对生物制剂和药物治疗的需求。

此外,人们越来越关注开发更安全的抗体。例如,修美乐(Humira)是一种人源化抗体,与传统的小鼠抗体相比,它不太可能引起副作用。随着人们对药物安全性的日益重视,这种更安全的抗体预计将变得更加普遍。然而,抗体发现市场的增长受到严格的监管政策以及基因治疗和小分子药物等替代药物需求激增的限制。此外,噬菌体展示、高通量筛选和生物信息学等技术进步正在促进新抗体的发现和开发。这带来了更高效、更具成本效益的药物开发过程,并为市场创造了利润丰厚的增长机会。

市场概述:

高度关注生物制剂的生物制药行业的扩张,导致对抗体研究服务的需求比以前更高。行业参与者和学术机构之间加强合作促进资源共享并加速抗体发现。向以患者为中心的药物开发的转变,强调个性化医疗和患者偏好,推动了抗体发现市场的发展。

高通量筛选、噬菌体展示和下一代测序等持续的技术进步已经导致抗体发现市场的改进抗体发现过程的效率和速度。政府组织和私营公司对研发活动的资助增加也刺激了抗体发现计划。单克隆抗体由于其针对特定抗原的特异性和有效性而在治疗应用中越来越受欢迎,从而导致对抗体研究服务的需求增加。因此,对基于抗体的疗法不断增长的需求和对外包的偏好可能会对未来几年的抗体发现市场预测产生重大影响。

战略见解

市场驱动因素:

增加研发投资推动市场增长

抗体(包括单克隆和多克隆)在学术、研究和制药机构和组织中得到应用,用于多种研发活动与药物和生物标志物开发以及其他治疗和临床诊断产品开发相关。中小企业每年都注重增加研发投入。 2020年4月,美国联邦政府根据《冠状病毒援助、救济和经济安全(CARES)法案》向生物医学高级研究与开发局(BARDA)拨款35亿美元,为制造、生产和采购提供财政支持疫苗、诊断、治疗和小分子活性药物成分 (API) 等。例如,2022 年 9 月,Abzena(生物制品和抗体药物偶联物领域的领导者)宣布打算扩大其在剑桥的研发能力,以帮助快速发现抗体。此外,制药公司 Bio-Rad 提供 10,000 种抗体以及抗原、试剂和缓冲液,用于开发体外诊断测试。因此,制药公司加大对抗体发现相关研发活动的投资,为各种疾病开发更好的治疗方案,推动抗体发现市场的增长。

细分分析:

抗体发现通过考虑以下部分进行市场分析:抗体类型、性质、服务和最终用户。

根据抗体类型,抗体发现市场分为单克隆抗体、多克隆抗体等。单克隆抗体细分市场在 2022 年占据最大的市场份额。此外,预计该细分市场在 2022 年至 2030 年期间复合年增长率最高,为 6.9%。单克隆抗体 (mAb) 旨在与患病细胞特异性相互作用,而不伤害健康细胞。癌症治疗是使用单克隆抗体的重要应用领域之一。这些是被广泛接受的生物制剂,预计在预测期内将为制药商带来数十亿美元的机会。此外,患者和医生越来越意识到单克隆抗体治疗的应用。因此,重磅单克隆抗体作为各种适应症的有效治疗方法的批准预计将有利于预测期内的抗体发现市场。 Avastin、Herceptin、Remicade、Rituxan等药物已被FDA批准用于治疗癌症、类风湿性关节炎、克罗恩病、溃疡性结肠炎等。

市场以性质为基础,分为人类和人类人源化、嵌合和鼠源化。人类和人源化细分市场在 2022 年占据最大的抗体发现市场份额,预计同一细分市场在预测期内将实现更高的复合年增长率。人类和人源化抗体是通过将具有所需抗原结合特异性的非人类抗体的互补决定区 (CDR) 移植到另一种抗体(更主要源自人类)的相应 CDR 中来进行基因工程改造的。这些抗体由于其更高的特异性和稳定性以及更低的成本而获得了广泛的接受和普及。此外,人类和人源化抗体在临床研究中表现出有吸引力的临床疗效。

抗体发现市场根据服务分为噬菌体展示、杂交瘤、转基因动物、酵母展示和单细胞。噬菌体展示细分市场在 2022 年占据主导地位,预计该细分市场在预测期内复合年增长率最高,为 7.3%。噬菌体展示技术用于体外抗体选择。感染细菌的病毒主要用作表达抗体片段(蛋白质)的基因载体,这些抗体片段通常是病毒上存在的单链可变片段(scFv)或Fab片段。然后可以检查表达的抗体片段与感兴趣的特定靶标的结合。与结合物识别过程相关的速度、简单性和成本效益是噬菌体展示技术的主要优势。

根据最终用户,抗体发现市场分为制药和生物技术公司、研究公司实验室等。制药和生物技术公司细分市场在 2022 年占据最大的抗体发现市场份额,预计该细分市场在 2022 年至 2030 年期间的复合年增长率将达到 7.2%。制药和生物技术公司在抗体发现过程中占据重要地位,因为它们有能力识别任何特定疾病的抗体并以商业规模生产它们。药物发现和开发对高特异性抗体的需求不断增加;蛋白质组学和基因组学领域的研究不断发展;对抗体识别新靶点和检测方法的需求不断增加;癌症、艾滋病毒/艾滋病、免疫缺陷疾病和血液疾病等多个治疗领域不断增加的研发活动是推动制药和生物技术公司对抗体发现产品、解决方案和服务需求的关键因素。

区域分析:

抗体发现市场报告的范围包括北美、欧洲、亚太地区、中东和非洲以及南美洲和中美洲。 2022年北美市场估值为12.9亿美元,预计到2030年将达到22.0亿美元;预计 2022 年至 2030 年复合年增长率为 6.8%。北美市场分为美国、加拿大和墨西哥。该地区的市场增长取决于癌症患病率的增加、抗体研究行业的强大存在以及研发领域的技术进步。

根据美国癌症协会的数据,约有 180 万新癌症患者2020 年,美国诊断出癌症病例,并记录了约 606,520 例与癌症相关的死亡。这增加了对治疗性抗体的需求,从而推动了市场增长。亚太地区预计 2022 年至 2030 年复合年增长率最高。亚太地区抗体发现市场分为中国、日本、印度、韩国、澳大利亚和亚太其他地区。 2022年中国占据最大市场份额,印度预计将呈现显着的市场增长速度。中国的生物制药行业正在经历巨大转变,从以仿制药为中心的格局演变为蓬勃发展的创新中心。此外,工业化的进步以及新药、高端医疗器械和技术的应用也有助于中国市场的增长。此外,越来越多的市场参与者专注于亚太地区国家的地理扩张和其他增长战略、研究中心数量的增加以及政府资金的显着增加,推动了亚太地区抗体发现市场的发展。
< br>主要参与者分析:

Creative Biolabs、Evotec、BioDuro-Sundia、Bruker Cellular Analysis、Biocytogen、Charles River Laboratories、Aragen Life Sciences Pvt. Ltd、Twist Bioscience、NanoCellect Biomedical 和 Sartorius AG 是抗体发现市场报告中介绍的主要参与者。

最新动态:

在抗体发现市场运营的公司采取了以下战略举措:例如并购、合作等。以下列出了近期的一些市场动态:

2024 年 1 月,百奥赛图制药有限公司推出了名为 RenBiologics 的新子品牌,代表该公司的抗体发现业务部门。 RenBiologics业务预计将涵盖该公司广泛的全人源抗体库的对外许可/共同开发,以及百奥赛图制药公司全人源抗体/TCR发现平台RenMice的许可。2023年12月,百奥赛图制药公司Co Ltd 宣布与 Ona Therapeutics 签订抗体评估、选择权和许可协议,以设计针对晚期癌症类型的生物制药。根据协议条款,百奥赛图制药有限公司授予 Ona 评估其专有的 RenMice 衍生的针对特定肿瘤靶标的全人源抗体的权限,并可选择独家许可选定的抗体用于抗体药物的开发、制造和商业化2022 年 6 月,Evotec SE 宣布与强生公司旗下药物发现公司之一杨森制药公司 (Janssen Pharmaceutica NV) 合作。根据此次合作,Evotec SE 旨在评估其 TargetAlloMod 平台,以发现具有新颖作用模式的一流治疗候选药物,而 Janssen Pharmaceutica NV 将促进这一目标。2021 年 8 月,Sartorius AG 与 McMaster 建立了合作伙伴关系大学致力于改进抗体的制造工艺以及其他基于病毒的疾病治疗方法,例如 COVID-19、癌症和遗传性疾病。与麦克马斯特大学的合作促成了具有影响力的研究,使重要的治疗方法得以更大规模地提供。
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Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

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Regional Scope
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North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

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Frequently Asked Questions


What is antibody discovery?

Antibody discovery, a nuanced endeavor, refers to the complicated process of discovering novel antibodies. This endeavor involves the search for antibodies that recognize and bind to specific targets, with applications extending to diagnostics and therapy. Antibody discovery methods such as phage display and hybridoma technology are widely used. Their use is essential to the search for antibodies that recognize and bind to specific targets, paving the way for applications in diagnostics and therapeutic interventions. The resulting outcome of this process plays a crucial role in developing novel drugs, vaccines, diagnostics, and various therapeutic modalities. By enabling researchers to produce antibodies tailored to recognize and target precise antigens, the scale of antibody discovery is of paramount importance.

What are the driving factors for the antibody discovery market across the globe?

Key factors that are driving the antibody discovery market are the increasing investments in research & development and the rising incidence of cancer.

What is the market CAGR value of antibody discovery market during forecast period?

The CAGR value of the antibody discovery market during the forecasted period of 2022-2030 is 6.7%.

Which antibody type segment leads the antibody discovery market?

The monoclonal antibodies segment held the largest share of the market in the global antibody discovery market and held the largest market share of 82.6% in 2022.

Which services held the largest share in the antibody discovery market?

The phage display segment dominated the global antibody discovery market and held the largest market share of 35.8% in 2022.

Who are the key players in the antibody discovery market?

The molecular spectroscopy market majorly consists of the players such Creative Biolabs, Evotec, BioDuro-Sundia, Bruker Cellular Analysis, Biocytogen, Charles River Laboratories, Aragen Life Sciences Pvt. Ltd, Twist Bioscience, NanoCellect Biomedical, and Sartorius AG.

Which are the top companies that hold the market share in antibody discovery market?

Charles River Laboratories and Evotec are the top two companies that hold huge market shares in the antibody discovery market.

Which region is expected to witness significant demand for antibody discovery market in the coming years?

Global antibody discovery market is segmented by region into North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America. The North America regional market is expected to grow with a CAGR of 6.8% during 2022–2030. Market growth in this region is attributed to the increasing prevalence of cancer, the strong presence of the antibody research industry, and technological advancements in the R&D sector help in the market expansion. An upsurge in funding further enables the development of new technologies, pooling of resources and expertise across countries and organizations, and conducting research work into existing antibody treatments. This has led to a better understanding of the immune system, and the development of effective and targeted antibodies. Additionally, the increased funding allows scientists to conduct large-scale clinical trials that are mandatory to evaluate the effectiveness of a particular antibody. The Asia Pacific molecular spectroscopy market is expected to grow at the highest CAGR of 7.3% during 2022–2030. China is predicted to hold the largest share of the market in 2022, and India is expected to show a significant growth rate in the market. China is predicted to hold the largest market share in 2022, and India is expected to show a significant growth rate in the market. The biopharmaceutical industry in China is undergoing a tremendous shift, evolving from a generics-focused landscape to a thriving innovation hub. Additionally, progress in industrialization, and the application of novel drugs, high-end medical devices, and techniques contribute to the antibody discovery market growth in China. Further, the growing number of market players focusing on countries in Asia Pacific for their geographic expansion and other growth strategies, the rising count of research centers, and a notable increase in government funding fuel the antibody discovery market growth in Asia Pacific.

The List of Companies - Antibody Discovery Market

  1. Creative Biolabs
  2. Evotec
  3. BioDuro-Sundia
  4. Bruker Cellular Analysis
  5. Biocytogen
  6. Charles River Laboratories
  7. Aragen Life Sciences Pvt. Ltd
  8. Twist Bioscience
  9. NanoCellect Biomedical
  10. Sartorius AG

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

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The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

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Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

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Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

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  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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