RNAi 治疗市场基于(关键地区、市场参与者、规模和份额)- 到 2031 年的预测

  • Report Code : TIPRE00007157
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 183
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2019 年 RNAi 治疗市场价值为 6.1879 亿美元,预计到 2027 年将达到 12.0929 亿美元;预计2020年至2027年复合年增长率为8.8%。

RNAi是指干扰RNA,负责控制和操纵细胞中的蛋白质翻译。这些 RNAi 用于沉默导致疾病的特定基因。目前,人们对 RNAi 的认识不断提高,因为它能够提供靶点特异性机制,从而带来更好的治疗结果。该方法广泛用于药物开发。增加对 RNAi 疗法开发的投资,加上传染病和慢性病的流行,预计将推动预测期内 RNAi 疗法市场的增长。然而,RNAi 疗法开发的高成本可能会限制市场的增长在预测年份。

RNAi 治疗市场利润丰厚的区域


< h3>市场洞察

RNAi 疗法的投资不断增加

RNAi 疗法的持续研发活动已经揭示了其在解决一系列慢性疾病方面的益处,例如遗传性疾病、肾脏疾病、神经退行性疾病和肿瘤学。 RNAi 疗法的有效性正在为新药开发带来投资。例如,2018年9月,Curamir Therapeutics, Inc.从Delos Capital获得了1000万美元的初始财务援助,用于开发基于miRNA的化疗耐药癌症药物。此外,2019年4月,Alnylam Pharmaceuticals Inc.宣布与Regeneron Pharmaceuticals建立战略合作伙伴关系,以发现和商业化RNAi治疗平台,用于治疗与眼睛、中枢神经系统和肝脏相关的疾病。两家公司在此次合作中投资了约10亿美元。此外,2020年1月,Dicerna Pharmaceuticals, Inc.和诺和诺德合作开发用于治疗肝病和心脏代谢紊乱的RNAi疗法。 Dicerna Pharmaceuticals, Inc. 收到诺和诺德 (Novo Nordisk) 约 1.75 亿美元的预付款,用于启动该项目。此外,根据合作条款,Dicerna Pharmaceuticals, Inc.将在头三年从诺和诺德每年获得近2500万美元用于该产品的开发。此类投资不仅可以帮助生物技术和制药公司推出新产品,还可以增加批准产品的数量。例如,2018年8月,Alnylam Pharmaceuticals, Inc.的Onpattro输注疗法获得美国食品和药物管理局(FDA)的批准,用于治疗周围神经疾病(多发性神经病)。市场参与者正在获得新药、疗法和技术研发的投资。这些对 RNAi 疗法的不断增加的投资正在推动市场的增长。

基于分子类型的见解

基于分子类型,RNAi 疗法市场分为小干扰RNA(siRNA)和微小RNA(miRNA)。小干扰 RNA (siRNA) 细分市场在 2019 年占据了更大的市场份额。该细分市场的增长归因于药物开发中对小干扰 RNA 的日益偏好以及研究合作伙伴数量的增加。此外,预计在预测期内,MicroRNA (miRNA) 细分市场将在全球 RNAi 治疗市场中实现更高的复合年增长率。

全球 RNAi 治疗市场(按分子类型) 2019年& 2027


基于应用的见解

根据应用,RNAi 治疗市场细分为肿瘤、心血管、呼吸系统疾病、肾脏疾病、遗传性疾病、神经退行性疾病、传染病等。 2019年,由于人们越来越偏好RNAi疗法来治疗癌症,肿瘤学领域占据了全球RNAi疗法市场的最大份额。此外,预计到 2027 年,肿瘤学领域的研究合作数量不断增加也将推动该细分市场的增长。然而,预计心血管疾病细分市场在预测期内的复合年增长率最高。

基于给药途径的见解

根据给药途径,RNAi 治疗市场分为肺部给药、静脉注射、皮内注射、腹膜内注射等。 2019年,肺部递送领域占据全球RNAi治疗市场的最大份额。然而,预计静脉注射细分市场在预测期内的复合年增长率最高。大量产品的推出以及静脉注射的广泛采用可能会对该细分市场的增长产生积极影响。

基于最终用户的见解

根据最终用户,RNAi 治疗市场进一步细分为研究和学术实验室、医院和诊断实验室。研究和学术实验室细分市场在 2019 年占据了最大的市场份额,预计在预测期内复合年增长率最高。

战略见解

欧洲
  • 法国
  • 德国
  • 意大利
  • 英国
  • 西班牙
  • 休息欧洲
  • 亚太地区(APAC)
    • 中国
    • 印度
    • 韩国
    • 日本
    • 澳大利亚
    • 亚太地区其他地区
  • 中东和非洲非洲 (MEA)
    • 南非
    • 沙特阿拉伯
    • 阿联酋
    • 中东和非洲其他地区
  • 南美洲和中美洲 (SAM)
    • 巴西
    • 阿根廷
    • SAM 的其他地区
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    公司简介

    • Alnylam Pharmaceuticals, Inc.
    • 赛诺菲
    • Olix Pharmaceuticals, Inc. .
    • 葛兰素史克公司。
    • Benitec Biopharma
    • Arbutus Biopharma Corporation
    • Silence Therapeutics
    • Rexahn Pharmaceuticals, Inc.
    • Arrowhead Pharmaceuticals,公司
    • 夸克
    Report Coverage
    Report Coverage

    Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

    Segment Covered
    Segment Covered

    This text is related
    to segments covered.

    Regional Scope
    Regional Scope

    North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

    Country Scope
    Country Scope

    This text is related
    to country scope.

    Frequently Asked Questions


    What is RNAi therapeutics?

    RNAi refers to the interference RNA which is responsible to control and manipulate protein translation in the cell. These RNAi are used to silence particular genes which are responsible for diseases. Currently, the awareness about RNAi is increasing extensively due to its ability to offer target specific mechanism, leading to superior treatment outcomes.

    What are the driving factors for the RNAi therapeutics system market across the globe?

    The factors that are driving growth of the market are growing investments in RNAitherapies and rising prevalence of chronic conditions and infectious diseases.Moreover, strategic activities by the manufacturersare offering lucrative opportunities for the growth of the market.

    Who are the major players in the RNAi therapeutics market?

    The RNAi therapeutics market majorly consists of the players such as Alnylam Pharmaceuticals, Inc., Sanofi, Olix Pharmaceuticals, Inc., Glaxosmithkline Plc., Benitec Biopharma, Arbutus Biopharma Corporation, Silence Therapeutics, Rexahn Pharmaceuticals, Inc., Arrowhead Pharmaceuticals, Inc., and Quark amongst others.

    The List of Companies - RNAi Therapeutics Market

    1. Alnylam Pharmaceuticals, Inc.
    2. Sanofi
    3. Olix Pharmaceuticals, Inc.
    4. Glaxosmithkline Plc.
    5. Benitec Biopharma
    6. Arbutus Biopharma Corporation
    7. Silence Therapeutics
    8. Rexahn Pharmaceuticals, Inc.
    9. Arrowhead Pharmaceuticals, Inc
    10. Quark

    The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

    1. Data Collection and Secondary Research:

    As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

    Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

    1. Primary Research:

    The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

    For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

    A typical research interview fulfils the following functions:

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    • Validates and strengthens in-house secondary research findings
    • Develops the analysis team’s expertise and market understanding

    Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

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    • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

    Below is the breakup of our primary respondents by company, designation, and region:

    Research Methodology

    Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

    1. Data Analysis:

    Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

    • Macro-Economic Factor Analysis:

    We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

    • Country Level Data:

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    • Company Profile:

    The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

    • Developing Base Number:

    Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

    1. Data Triangulation and Final Review:

    The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

    We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

    We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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