Se estima que el tamaño del mercado de la narcolepsia alcanzará los 4.537,9 millones de dólares en 2027, frente a los 2.026,8 millones de dólares de 2018; se estima que crecerá a una tasa compuesta anual del 9,5 % durante 2019-2027.
La narcolepsia es un raro trastorno cerebral a largo plazo caracterizado por somnolencia excesiva, parálisis del sueño y alucinaciones. y episodios de cataplejía entre ciertos pacientes. Se sabe que la narcolepsia ocurre por igual entre hombres y mujeres, y se estima que la incidencia global de la narcolepsia es aproximadamente de 1 de cada 2000 personas. Las personas con narcolepsia sienten mucho sueño durante el día y pueden quedarse dormidas involuntariamente durante sus actividades normales. Además, la narcolepsia se caracteriza por somnolencia excesiva y episodios de sueño. La narcolepsia dificulta que las personas permanezcan despiertas durante períodos prolongados y les produce sueño durante la mayor parte del día.
El crecimiento del mercado de la narcolepsia se atribuye a la creciente prevalencia de trastornos neurológicos relacionados con el sueño, que están surgiendo compañías farmacéuticas y biofarmacéuticas locales, y aumentar la conciencia sobre los trastornos neurológicos. Sin embargo, es probable que los efectos secundarios y los riesgos asociados con los medicamentos para la narcolepsia y el retraso en el diagnóstico y el diagnóstico erróneo de la enfermedad tengan un impacto negativo en el crecimiento del mercado de la narcolepsia.
regiones lucrativas para el mercado de la narcolepsia
Perspectivas del mercado
La creciente prevalencia de trastornos neurológicos relacionados con el sueño impulsa el mercado de la narcolepsia
La variedad del sueño Los trastornos que tratan los neurólogos son amplios e incluyen afecciones como el insomnio, la apnea del sueño, el síndrome de piernas inquietas y la narcolepsia. Estos trastornos provocan alteraciones en los mecanismos normales del sueño y la vigilia que provocan anomalías endógenas. Se espera que los trastornos neurológicos relacionados con el sueño aumenten en los próximos años, a medida que una gran parte de la población envejecerá. Según el Instituto Nacional de Salud (NIH), aproximadamente 40 millones de estadounidenses sufren enfermedades neurológicas en los EE. UU. y 20 millones de personas experimentan problemas ocasionales para dormir.
Durante las últimas décadas, se ha aprendido mucho sobre las Fisiopatología de la narcolepsia. Según el Centro Nacional de Información Biotecnológica, la prevalencia de la narcolepsia con cataplejía ha sido examinada en numerosos estudios y se sitúa entre 25 y 50 por 100.000 personas. Además, según Narcolepsy Network 2017, la afección afecta a 1 de cada 2.000 personas en EE. UU., es decir, 200.000 estadounidenses y aproximadamente 3 millones en todo el mundo. Además, la Asociación Estadounidense de Apnea del Sueño informa que los problemas relacionados con el sueño afectan a entre 50 y 70 millones de estadounidenses de todas las edades y clases socioeconómicas. Sin embargo, se han identificado importantes disparidades en la prevalencia y gravedad de ciertos trastornos del sueño en minorías y poblaciones desatendidas. Más de 50 millones de estadounidenses ya sufren más de 80 trastornos del sueño diferentes y otros 20 a 30 millones sufren problemas de sueño intermitente cada año.
Las personas con narcolepsia sufren de somnolencia diurna crónica y episodios en los que se quedan dormidos. inesperadamente durante el día. Estos "ataques de sueño" pueden ocurrir en cualquier momento, durante cualquier actividad. Los ataques de sueño no se limitan a períodos de actividades aburridas o de baja participación, sino que pueden ocurrir durante el horario escolar o laboral, en medio de una conversación, mientras come, mientras hace ejercicio o practica deportes, o incluso mientras conduce. Por lo tanto, es probable que el aumento en la prevalencia de trastornos neurológicos relacionados con el sueño impulse las tendencias del mercado de la narcolepsia durante el período de pronóstico.
Información basada en tipos< /h3>
El mercado mundial de narcolepsia, según el tipo, se segmenta en narcolepsia con cataplejía, narcolepsia sin cataplejía y narcolepsia secundaria. El segmento de narcolepsia con cataplexia tuvo la mayor participación entre los subsegmentos de tipo en el mercado de narcolepsia en 2018 y también se prevé que sea testigo de una tendencia similar durante el período previsto. La narcolepsia con cataplejía, también conocida como narcolepsia tipo 1, es un trastorno neurológico poco común que se diagnostica en función de niveles bajos de una hormona cerebral (hipocretina) o eventos reportados de cataplejía en un individuo. La cataplejía se refiere a una debilidad o parálisis muscular repentina e incontrolable que ocurre principalmente en un día y a menudo es provocada por emociones fuertes, como la excitación o la risa. La persona pierde tono muscular y puede tener mandíbula flácida, habla entrecortada, rodillas dobladas o debilidad total en la cara, brazos, piernas y tronco, sin mucho aviso. La pérdida del tono muscular en la cataplexia se produce debido a la incapacidad de regular el sueño y los estados de vigilia. En aproximadamente el 10% de los casos de narcolepsia, la cataplexia es el primer síntoma que aparece y puede diagnosticarse erróneamente como un trastorno convulsivo.
Información basada en productos
El mercado mundial de la narcolepsia, según el producto, se segmenta en estimulantes del sistema nervioso central (SNC), oxibato de sodio y antidepresivos. El segmento de oxibato de sodio tuvo la mayor participación de mercado de narcolepsia en 2018. Se sabe que el oxibato de sodio, también conocido como gamma-hidroxibutirato (GHB), reduce la somnolencia diurna y la cataplexia al mejorar el sueño nocturno en pacientes con narcolepsia. El GHB se utiliza para tratar la narcolepsia, una afección que provoca somnolencia diurna intensa. El oxibato de sodio puede disminuir la somnolencia diurna y también reducir la cantidad de ataques cortos repentinos de músculos débiles o paralizados (conocidos como cataplexia) que pueden ocurrir en pacientes con narcolepsia. Este medicamento es muy eficaz para la cataplexia. El oxibato de sodio ayuda a mejorar el sueño nocturno, que suele ser deficiente en la narcolepsia. En dosis altas, también puede ayudar a controlar la somnolencia diurna. Debe tomarse en dos dosis, una antes de acostarse y otra hasta cuatro horas después.
Información basada en canales de distribución
La narcolepsia global El mercado, según el canal de distribución, se divide en farmacias hospitalarias y farmacias minoristas. El segmento de farmacias hospitalarias lideró el mercado de la narcolepsia en 2018. Las farmacias hospitalarias se refieren a las farmacias médicas situadas habitualmente en las instalaciones del hospital. Estas farmacias tienen una gran cantidad de medicamentos que incluyen principalmente medicamentos especializados y en investigación. Las farmacias hospitalarias generalmente proporcionan medicamentos solo para pacientes hospitalizados y no son establecimientos minoristas. Las farmacias de los hospitales pueden proporcionar una gran cantidad de medicamentos por día asignados a las salas y unidades de cuidados intensivos de acuerdo con el cronograma de medicación del paciente. Los hospitales más grandes pueden utilizar sistemas de transporte automatizados para ayudar en la distribución eficiente de medicamentos.
Información estratégica
Los lanzamientos y aprobaciones de productos son estrategias comúnmente adoptadas por empresas para expandir su presencia global y carteras de productos. Además, los jugadores se centran en la estrategia de asociación para ampliar su clientela, lo que, a su vez, les permite mantener su marca en todo el mundo. Se prevé que la cuota de mercado florezca con el desarrollo de nuevos productos innovadores por parte de los actores del mercado. Algunos de los participantes del mercado que ofrecen productos son Teva Pharmaceutical Industries Ltd; Jazz Pharmaceuticals plc; Arena Pharmaceuticals, Inc; Graymark Healthcare, Inc; Novartis AG; Takeda Pharmaceutical Company Limited; Mylan NV; BIOPROYECTO; Shionogi &erio; Co., Ltd; y Ligand Pharmaceuticals, Inc.
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
The List of Companies
- Bioprojet
- Teva Pharmaceutical Industries Ltd.
- Jazz Pharmaceuticals, Inc.
- Graymark Healthcare, Inc.
- Arena Pharmaceuticals, Inc.
- Shire (Acquired by Takeda)
- Ligand Pharmaceuticals, Inc.
- Novartis AG
- Mylan N.V.
- Shionogi Inc.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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