发作性睡病市场基于(关键地区、市场参与者、规模和份额)- 到 2031 年的预测

  • Report Code : TIPRE00003326
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 153
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发作性睡病市场规模预计将从 2018 年的 20.268 亿美元增至 2027 年的 45.379 亿美元;预计 2019-2027 年复合年增长率为 9.5%。

发作性睡病是一种罕见的长期脑部疾病,其特征是过度嗜睡、睡眠麻痹、幻觉,以及某些患者的猝倒发作。据了解,发作性睡病在男性和女性中的发病率相同,全球发作性睡病的发病率估计约为每 2,000 人中就有 1 人发病。患有发作性睡病的人白天会感到非常困倦,在正常活动时可能会不由自主地睡着。此外,发作性睡病的特征是过度嗜睡和睡眠发作。发作性睡病使人们难以长时间保持清醒,并使他们在一天中的大部分时间都处于昏昏欲睡的状态。

发作性睡病市场的增长归因于与睡眠相关的神经系统疾病的患病率上升,新兴的当地制药和生物制药公司,并提高对神经系统疾病的认识。然而,与发作性睡病药物相关的副作用和风险以及疾病的延迟诊断和误诊可能会对发作性睡病市场的增长产生负面影响。

利润丰厚的地区发作性睡病市场


市场洞察
睡眠相关神经系统疾病患病率上升推动发作性睡病市场

睡眠范围神经科医生治疗的疾病范围很广,包括失眠、睡眠呼吸暂停、不宁腿综合症和发作性睡病等。这些疾病会破坏正常的睡眠和觉醒机制,从而导致内源性异常。由于大部分人口将进入老年,预计未来几年与神经性睡眠相关的疾病将会增加。根据美国国立卫生研究院 (NIH) 的数据,美国约有 4000 万美国人患有神经系统疾病,2000 万人偶尔会出现睡眠问题。

在过去的几十年里,人们对睡眠问题有了很多了解。发作性睡病的病理生理学。根据国家生物技术信息中心的数据,许多研究都对发作性睡病伴猝倒的患病率进行了检验,发现每 10 万人中有 25 至 50 人患有发作性睡病。此外,根据 2017 年发作性睡病网络的数据,美国每 2,000 人中就有 1 人患有这种疾病,即 200,000 名美国人和全球约 300 万人。此外,美国睡眠呼吸暂停协会报告称,睡眠相关问题影响着 50—7000 万各个年龄段和社会经济阶层的美国人。然而,在少数族裔和服务不足的人群中,某些睡眠障碍的患病率和严重程度存在显着差异。超过 5000 万美国人已经患有 80 多种不同的睡眠障碍,每年还有 20—3000 万美国人患有间歇性睡眠问题。

患有发作性睡病的人患有慢性日间嗜睡和入睡发作。没想到白天。这些“睡眠发作”可能发生在任何时间、任何活动期间。睡眠发作不仅限于沉闷或低参与活动的时期,还可能发生在上学或工作时间、谈话过程中、吃饭时、锻炼或参加运动时,甚至开车时。因此,与睡眠相关的神经系统疾病患病率的激增可能会推动预测期内发作性睡病市场的趋势。

基于类型的见解< /h3>

全球发作性睡病市场根据类型分为发作性睡病伴猝倒症、发作性睡病不伴猝倒症和继发性发作性睡病。 2018 年,发作性睡病伴猝倒细分市场在发作性睡病市场的细分类型中占有最大份额,预计在预测期内也将出现类似的趋势。伴有猝倒的发作性睡病也称为 1 型发作性睡病,是一种罕见的神经系统疾病,根据脑激素(下丘脑分泌素)水平较低或报告的个体猝倒事件进行诊断。猝倒是指突然且无法控制的肌肉无力或瘫痪,主要发生在一天内,通常由强烈的情绪(例如兴奋或大笑)引发。患者会失去肌肉张力,下巴松弛,言语不通,膝盖弯曲,或者面部、手臂、腿部和躯干完全无力,而没有太多征兆。猝倒症中肌张力的丧失是由于无法调节睡眠和清醒状态而发生的。在大约 10% 的发作性睡病病例中,猝倒是第一个出现的症状,可能会被误诊为癫痫病。

基于产品的见解

全球发作性睡病市场根据产品分为中枢神经系统 (CNS) 兴奋剂、羟丁酸钠和抗抑郁药。 2018 年,羟丁酸钠细分市场占据了最大的嗜睡症市场份额。羟丁酸钠也称为 γ-羟基丁酸盐 (GHB),已知可通过改善嗜睡症患者的夜间睡眠来减少白天嗜睡和猝倒。 GHB 用于治疗发作性睡病,这是一种导致白天严重嗜睡的疾病。羟丁酸钠可以减少白天的嗜睡,还可以减少发作性睡病患者可能发生的肌肉无力/麻痹(称为猝倒)的突然短暂发作的次数。这种药物对猝倒非常有效。羟丁酸钠有助于改善夜间睡眠,而发作性睡病患者的夜间睡眠通常很差。高剂量时,它还可能有助于控制白天的嗜睡。它必须分两剂服用,一剂在睡前服用,一剂在四小时后服用。

基于分销渠道的见解

全球发作性睡病市场根据分销渠道分为医院药房和零售药房。 2018年,医院药房细分市场引领嗜睡症市场。医院药房是指通常位于医院场所的医疗药房。这些药房库存有大量药物,主要包括专用药物和研究药物。医院药房通常只为住院患者提供药物,而不是零售场所。医院药房每天可以提供大量药物,根据患者的用药时间表分配给病房和重症监护室。较大的医院可能会使用自动运输系统来帮助有效分配药物。

战略见解

产品发布和批准是医疗机构普遍采用的策略公司扩大其全球足迹和产品组合。此外,参与者专注于扩大客户群的合作伙伴战略,这反过来又使他们能够在全球范围内保持自己的品牌声誉。随着市场参与者开发新的创新产品,市场份额预计将不断扩大。提供产品的一些市场参与者包括 Teva Pharmaceutical Industries Ltd;爵士制药有限公司;阿瑞娜制药公司;格雷马克医疗保健公司;诺华公司;武田制药有限公司;迈兰公司;生物项目;盐野义有限公司;和配体制药公司

Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

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to country scope.

The List of Companies

  1. Bioprojet
  2. Teva Pharmaceutical Industries Ltd.
  3. Jazz Pharmaceuticals, Inc.
  4. Graymark Healthcare, Inc.
  5. Arena Pharmaceuticals, Inc.
  6. Shire (Acquired by Takeda)
  7. Ligand Pharmaceuticals, Inc.
  8. Novartis AG
  9. Mylan N.V.
  10. Shionogi Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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