Le marché de l'homocystinurie devrait atteindre 73,96 millions de dollars US d'ici 2028, contre 56,58 millions de dollars US en 2021 ; on estime qu'il croîtra à un TCAC de 3,9 % entre 2021 et 2028.
L'homocystinurie est une maladie génétique dans laquelle le corps est incapable de digérer correctement certains blocs de construction protéiques (acides aminés). L'homocystinurie se décline en une variété de types, chacun avec son propre ensemble de signes et de symptômes ainsi qu'une étiologie héréditaire. La myopie (myopie), la luxation du cristallin à l'avant de l'il, un risque accru de coagulation sanguine irrégulière et des os fragiles sujets aux fractures (ostéoporose) ou à d'autres anomalies squelettiques définissent la forme la plus répandue d'homocystinurie. Certaines des personnes touchées ont également des retards de développement et des difficultés d'apprentissage.
Aperçus stratégiques
La croissance du marché de l'homocystinurie est attribuée aux carences croissantes en vitamine B6 et en vitamine B12 et la prévalence croissante des troubles métaboliques héréditaires. Cependant, le manque de sensibilisation à divers troubles rares et troubles métaboliques héréditaires entrave la croissance du marché.
Régions lucratives sur le marché de l'homocystinurie
Perspectives du marchéLa hausse des carences en vitamine B6 et en vitamine B12 stimule le marché de l'homocystinurie< /h3>
L'augmentation des carences en vitamine B6 et en vitamine B12 entraîne plusieurs troubles tels que l'anémie, l'anémie mégaloblastique, l'anémie microcytaire et certains types de troubles métaboliques, ce qui devrait stimuler la croissance du marché au cours de la période de prévision. Comme la thérapie à la vitamine B6 est considérée comme une thérapie efficace contre l'homocystinurie, la carence en cette vitamine peut aggraver l'état. La pyridoxine (vitamine B6) agit comme cofacteur de la bêta-synthase et agit comme chaperon pour stabiliser plusieurs mutations faux-sens. Certains des patients atteints d'homocystinurie répondent bien au traitement à la pyridoxine, et cela aide à abaisser les niveaux d'homocystéine, soulageant ainsi la maladie. Ainsi, la vitamine B6 est considérée comme vitale dans la gestion de l'homocystinurie car un nombre limité de traitements sont disponibles pour guérir la maladie. La déficience de cette enzyme entraîne une anémie et une anémie microcytaire. La prévalence croissante de l'anémie devrait stimuler la croissance du marché au cours de la période de prévision. Par exemple, selon l'Organisation mondiale de la santé, l'anémie touche plus de 1,62 milliard de personnes, soit 24,8 % de la population. Les principales causes de l'anémie sont une mauvaise alimentation et des carences en vitamines telles que B6, B9 et B12. Principalement, la carence en vitamine B6 est une cause majeure d'anémie. Ainsi, une augmentation des cas de carence en vitamine B6 et une prévalence élevée des troubles associés à sa carence devraient soutenir la croissance du marché au cours de la période de prévision.
Method-Based Insights
The Le marché mondial de l'homocystinurie, basé sur la méthode, est divisé en traitement et diagnostic. Le segment du traitement détenait une plus grande part du marché en 2021. De plus, le même segment devrait enregistrer un TCAC plus élevé sur le marché au cours de la période de prévision en raison de l'utilisation actuelle du traitement et de l'augmentation de la recherche et du développement de nouveaux traitements pour l'homocystinurie.
Marché de l'homocystinurie, par méthode - 2021 et 2028
Informations basées sur l'utilisateur final
Le marché mondial de l'homocystinurie, basé sur l'utilisateur final, est segmenté en laboratoires de diagnostic et d'imagerie, hôpitaux et cliniques, cliniques spécialisées et instituts universitaires et de recherche. En 2021, le segment des laboratoires de diagnostic et d'imagerie détenait la plus grande part de marché. De plus, le segment devrait enregistrer le TCAC le plus élevé de 4,2 % au cours de la période 2021-2028 en raison de l'augmentation des diagnostics de troubles métaboliques héréditaires dans les laboratoires de diagnostic et d'imagerie.
Les lancements et les approbations de produits sont des stratégies couramment adoptées par les entreprises. pour étendre leur empreinte mondiale et leurs portefeuilles de produits. De plus, les acteurs du marché de l'homocystinurie se concentrent sur la stratégie de partenariat pour élargir leur clientèle, ce qui leur permet de maintenir leur marque à travers le monde.
Le rapport segmente le marché de l'homocystinurie comme suit
Marché de l'homocystinurie - par méthode
- Traitement
- Pyridoxine
- Bétaïne
- Autres
- Diagnostic
- Tests génétiques
- Test de dépistage des acides aminés
- Test des enzymes hépatiques
- Autres
< /ul>
Marché de l'homocystinurie - par utilisateur final
- Hôpitaux et cliniques
- Laboratoires de diagnostic et d'imagerie
- Cliniques spécialisées
- Instituts universitaires et de recherche
Marché de l'homocystinurie - par géographie
- Amérique du Nord
- États-Unis< /li>
- Canada
- Mexique
- Europe
- Royaume-Uni
- Allemagne
- France
- Italie
- Espagne
- Reste de l'Europe
- Asie-Pacifique
- Chine
- Japon
- Inde
- Australie
- Corée du Sud
- Reste de l'Asie-Pacifique
li>
- Moyen-Orient et Afrique
- EAU
- Arabie saoudite
- Afrique du Sud
- Reste du Moyen-Orient et de l'Afrique
- Amérique du Sud et centrale
- Brésil
- Argentine
- Reste de l'Amérique du Sud et centrale Amérique centrale
Profils des entreprises
- BASF SE
- HUAZHONG PHARMACEUTICAL
- Pfizer Inc.
- MYLAN NV
- Aeglea BioTherapeutics
- Amino GMBH
- KAO Corporation
- DSM Corporation< /li>
- Orphan Technologies
- Fresenius Kabi AG
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
The global Homocystinuria market is expected to reach US$ 73,960.22 thousand by 2028 from US$ 56,589.20 thousand in 2021; it is estimated to grow at a CAGR of 3.9% during 2021-2028.
Emergence of human enzyme therapeutics and enzyme replacement therapy to treat rare disorders is one of the future trends of homocystinuria market. Enzyme replacement therapy and enzyme therapeutics is a type of novel drug therapy in which therapeutic enzymes are used to treat chronic and life-threatening diseases such as cancer, idiosyncratic disorders, and rare disorders. Furthermore, if an enzyme is not functioning properly in the body, then enzyme replacement therapy is used for replacing the enzyme that is deficient in the body. Enzymes have a predominant role in pharmaceutical industries and drug development as they treat various disorders. The advancements in the field of protein technology, recombinant DNA technology, enzyme immobilization, and nanotechnology have provided a solid platform for the use of enzymes in the treatment of various disorders.
The growth of the Homocystinuria market is mainly attributed to factors such as the increasing prevalence of inherited metabolic disorders coupled with rise in vitamin B6 and Vitamin B12 deficiencies. However, the lack of awareness about various rare disorders and inherited metabolic disorders is hindering the market growth.
The Asia Pacific region is expected to be the fastest-growing region among all other regions. The market in this region is expected to grow significantly in countries such as, China, Japan and India. The market is driven by increase in prevalence of inherited metabolic disorders, rise in government initiatives to manage rare diseases across the region along with increase in diagnostic tests across the region such as new born screening test etc. Therefore, the region holds huge potential for the homocystinuria market players to grow during the forecast period.
Homocystinuria is an inherited disorder in which the body is unable to process certain building blocks of proteins (amino acids) properly. There are multiple forms of homocystinuria, which are distinguished by their signs and symptoms and genetic cause. The most common form of homocystinuria is characterized by nearsightedness (myopia), dislocation of the lens at the front of the eye, an increased risk of abnormal blood clotting, and brittle bones that are prone to fracture (osteoporosis) or other skeletal abnormalities. Some affected individuals also have developmental delay and learning problems.
The List of Companies - Homocystinuria Market
- BASF SE
- HUAZHONG PHARMACEUTICAL
- Pfizer Inc.
- MYLAN N.V
- Aeglea BioTherapeutics
- Amino GMBH
- KAO Corporation
- DSM Corporation
- Orphan Technologies
- Fresenius Kabi AG.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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