The MENA knee cartilage repair market size was US$ 57,730.82 thousand in 2022, and it is projected to reach US$ 79,443.64 thousand by 2028; the market is estimated to record a CAGR of 5.5% from 2023 to 2028. 

Market Insights and Analyst View:

The MENA knee cartilage repair market is likely to grow due to rise in prevalence of osteoarthritis and developments in orthopedic field. In addition, MENA knee cartilage repair market trends such as artificial intelligence to diagnose cartilage defects and three dimensional bioprinting of articular cartilage will have positive impact which will boost the MENA knee cartilage repair market size. Moreover, other factors that give rise to the incidence are obesity and menopause in females are boosting the MENA knee cartilage repair market growth.

Furthermore, the companies operating in the market are significantly involved in aggressive research and development and are focusing on expanding their customer base in developing regions. For instance, in March 2022, US Food and Drug Administration had granted Premarket Approval (PMA) for its Agili-C implant of CartiHeal Ltd. CartiHeal Ltd., is a developer of implants for the treatment of cartilage and osteochondral defects in arthritic and non-arthritic knee joints. The service will be provided in Saudi Arabia, UAE, Egypt, Israel, and rest of MENA. Such strategic decisions are also enabling MENA knee cartilage repair market growth during 2020–2028.

Growth Drivers and Challenges:

Organizations and market players are investing in the development of the orthopedic field in the Middle East and North Africa through various means. For instance, in November 2022, Zimmer Biomet inaugurated a new Innovation Hub in Dubai to showcase its technological advancements, surgical robots, and implants. In January 2022, Zimmer Biomet expanded its office in Dubai to meet the growing demand from hospitals and clinics in the Middle East, North Africa, and Turkey (MENAT). This strategic decision by the company is expected to influence the market's growth in the near future.

Similarly, the number of orthopedic clinics is expanding in the region. In January 2023, Burjeel Holdings—one of the leading private healthcare service providers in MENA—collaborated with the Paley Middle East Clinic to open a new clinic in Burjeel Medical City, Abu Dhabi. The collaboration aims to provide world-class specialized orthopedic care. The new clinic will also expand the Paley Institute’s medical tourism in the Middle East and Africa.

Moreover, regional companies are receiving product approvals for their developments in the field of cartilage repair. In March 2022, Israel-based CartiHeal Ltd received premarket approval from the US Food and Drug Administration (FDA) for its Agili-C implant. CartiHeal Ltd is an implant developer that develops products for the treatment of cartilage and osteochondral defects in arthritic and non-arthritic knee joints. Agili-C is designed to treat International Cartilage Repair Society (ICRS) grade III or above knee-joint surface lesion(s). Such developments in the orthopedic field are driving the MENA knee cartilage repair market growth.

On the other hand, the growth of the knee cartilage repair market is anticipated to face several challenges due to growing developments in stem cell therapy. Companies have been introducing stem cell injections that can treat knee osteoarthritis. For instance, RegenOrthoSport launched Regenexx in the market. It is a new kind of needle-based injection to treat knee arthritis that enables the regeneration of healthy cartilage tissue in the damaged part of the knee. The injection contains autologous stem cells that are derived from the patient’s bone marrow that are used to treat damaged part of the knee and protects the healthy tissue surroundingit. Thus, stem cell therapy has shown promising results, and it has the potential to replace the traditional or conservative treatments of chronic knee conditions, such as medications, physical therapy, and surgical intervention. The stem cells’ capacity for regenerating has paved the way for novel regenerative therapies in the field of orthopedics.

Countries in the Middle East and North Africa are aggressively adopting advanced medical therapies to treat chronic conditions. The presence of such products in the market hinders the use of knee cartilage repair devices and slows down the market’s growth.

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MENA Knee Cartilage Repair Market: Strategic Insights

Market Size Value in	US$ 57,730.82 thousand in 2022
Market Size Value by	US$ 79,443.64 thousand by 2028
Growth rate	CAGR of 5.5% from 2023 to 2028
Forecast Period	2023-2028
Base Year	2022

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Report Segmentation and Scope:

The “MENA Knee Cartilage Repair Market” is segmented based on procedure type, product, end user, and geography. Based on the product type, the MENA knee cartilage repair market is segmented into arthroscopic chondroplasty, cell-based cartilage resurfacing, osteochondral grafts transplantation, and others. Based on product, the MENA knee cartilage repair market is segmented into screws & implants, arthroscopic systems, and others. Based on end user, the market is segmented into hospitals, ambulatory surgical centers, and orthopedic clinics. On the basis of region is segmented into Saudi Arabia, UAE, Egypt, Israel, and the Rest of Middle East & North Africa.

Segmental Analysis:

Based on procedure type, the MENA knee cartilage repair market is segmented into arthroscopic chondroplasty, cell-based cartilage resurfacing, osteochondral grafts transplantation, and others. The arthroscopic chondroplasty segment held the largest MENA knee cartilage repair market share in 2022. The segment is anticipated to register the highest CAGR in the market during 2022–2028. Damaged cartilage's rough and irregular surface causes pain, joint inflammation, and difficulty walking. If left untreated, it gradually degenerates the bones of the joints causing arthritis. The damaged cartilage does not heal on its own, and in such cases, arthroscopic chondroplasty prepares the joint for cartilage restorative procedures. Arthroscopic chondroplasty is recommended in case of mild to moderate cartilage wear or a cartilage injury in the joint, damaged cartilage in the knee rather than widespread or irreparable cartilage damage. Arthroscopic chondroplasty is a commonly performed surgical procedure using an arthroscope (a small, fiber-optic instrument comprising a lens, light source, and video camera) during knee arthroscopy. During the process, the doctor creates two to five small incisions around the front of the knee. An arthroscopic camera is inserted through one of the incisions, and other incisions act as access points for other arthroscopic tools. The doctor carefully removes the small patch of damaged cartilage with the help of small surgical tools. Removing damaged tissue allows healthy cartilage to grow, and as the knee heals, new "scar tissue" cartilage grows on damaged tissue spots to replace the missing cartilage. The benefits of chondroplasty include improved joint function, reduced joint pain, slowed cartilage degeneration, and immediate relief. In general, recovery from an arthroscopic procedure is faster and less painful compared to recovery from traditional surgery.

MENA Knee Cartilage Repair Market, by Procedure Type – 2022 and 2028

Access Data

Based on product, the MENA knee cartilage repair market is segmented into implants, screws, arthroscope, and others. The arthroscopic system segment held the largest MENA knee cartilage repair market share in 2022. However, screws & implant segment is anticipated to register the highest CAGR in the market during 2022–2028.

Based on end user, the MENA knee cartilage repair market is segmented into hospitals, ambulatory surgical centers, and orthopedic clinics. The hospitals segment held the largest share of the market in 2022. The hospitals segment is anticipated to register the highest CAGR in the market during 2022–2028.

Regional Analysis:

Based on region, the MENA knee cartilage repair market is divided into key countries: Saudi Arabia, UAE, Egypt, Israel, and the rest of MENA. The regional market growth is attributed to various factors such as the growing population base, increasing prevalence of chronic diseases and low cost of treatment for orthopedic injuries. Saudi Arabia is one of the fastest-growing countries in the MENA, driven by a huge population base and an increase in the prevalence of chronic diseases. Saudi Arabia has seen a significant change in lifestyle due to the rapid economic transition and associated technological and social changes. A high sedentary behavior and a change in dietary patterns, with people favoring energy-dense foods such as fast foods and sugar-sweetened beverages over nutrient-dense foods was observed. 

In a study titled "Fast-Food Consumption, Dietary Quality, and Dietary Intake of Adolescents in Saudi Arabia," published in November 2022, high fast-food and junk food consumption was observed in 2020, accounting for 87% of the studied sample in Saudi Arabia. As per the study, 85% of Saudi adolescents preferred fast food instead of homemade food. Approximately 28.5% of the participants ate fast food more than twice a week. The increased consumption of fast food among adolescents poses a significant public health concern and can lead to an increased risk of obesity and several noncommunicable diseases in adulthood. Obese patients are more prone to developing knee injuries than normal BMI patients, as more weight puts more strain on joints and the cartilage protecting the ends of bones. In addition, excess weight is a risk factor for osteoarthritis as the increased stress on the joints wears down the cartilage at the ends of bones quickly. As per an Al Arabiya Network article and the latest figures revealed ahead of World Obesity Day (March 4) in 2023, ~60% of the country's adult population is overweight or obese, and anterior cruciate ligament (ACL) injury is among the most common orthopedic injuries. A high body mass index (BMI) can contribute to the development of noncontact ACL injury, and the risk of ACL tears was significantly higher across obese patients. Thus, the factors mentioned above are expected to provide growth opportunities for the knee cartilage repair market in the country.

Industry Developments and Future Opportunities:

Various initiatives taken by key players operating in the MENA knee cartilage repair market are listed below:

1. In December 2021, DePuy Synthes Acquired OrthoSpin, Ltd. OrthoSpin developed and manufactures a first-of-its kind technology – an automated strut system – which is used in conjunction with DePuy Synthes MAXFRAME Multi-Axial Correction System, an external ring fixation system. This acquisition is a clear example of Johnson & Johnson’s continued commitment to advancing innovation in the medtech space.
2. In March 2022, US Food and Drug Administration had granted Premarket Approval (PMA) for its Agili-C implant of CartiHeal Ltd. CartiHeal Ltd., is a developer of implants for the treatment of cartilage and osteochondral defects in arthritic and non-arthritic knee joints.

The companies have been implementing various strategies that have helped the growth of the company and in turn have brought about various changes in the market. The companies have utilized organic strategies such as launches, expansion, and product approvals. On the flip side, inorganic strategies, such as product launches, partnerships, and collaborations, were widely seen in the MENA knee cartilage repair market.

Covid-19 Impact:

In the past several decades, countries in the MENA region have strengthened their health systems and upgraded public and commercial healthcare. However, the limited availability of resources, including trained staff and medical equipment, and the burden of noncommunicable diseases harm the overall healthcare system in the region. In 2020, the COVID-19 pandemic significantly impacted the delivery and accessibility of social services, education, health and nutrition, healthcare spending, and wellbeing- and development-related businesses in the region. Due to the region's dependence on trade and tourism, and struggles with substantial youth unemployment, the global crisis has caused serious long-term effects in the region.

Preemptive action by governments helped them flatten the infection curve in their respective countries. With the gradual recovery of countries from the COVID-19 pandemic, authorities are working on improving their resilience and digitally efficient healthcare systems. Furthermore, the trend of consumerization in healthcare, which provides greater authority and decision-making power to patients, is driving the paradigm shift toward value-based care in the region. After the beginning of the COVID-19 pandemic, the World Bank Group committed more than US$ 157 billion to combat the effects of the crisis on health, economies, and social aspects. More than 100 countries benefit from the fund, which is used to improve preparedness, protect the poor and jobs, and kickstart a climate-friendly recovery.

Moreover, elective procedures were cancelled, which caused a decrease in the patient pool, and surgical procedures were adversely affected. The COVID-19 pandemic reduced the number of orthopedic procedures in 2020, as public health networks did have a more significant adverse impact on elective surgeries due to a slower recovery than private institutions, and only emergency surgeries were performed, which impacted the knee cartilage repair market growth. However, an increase in the number of people on the waiting list to undergo knee surgeries will widen the access gap to orthopedic surgery, ultimately impacting the market growth rate.

Competitive Landscape and Key Companies:

Some of the prominent players operating in the MEAN knee cartilage repair market include Arthrex Inc, Medical Device Business Services Inc, Zimmer Biomet Holdings Inc, Medacta Group SA, Anika Therapeutics Inc, Conmed Corp; Stryker Corp, CartiHeal Inc, Smith & Nephew Plc, and B. Braun SE amongst others. These companies focus on new product launches and geographical expansions to meet the growing demand worldwide and increase their product range in specialty portfolios. They have a widespread global presence, which help them to serve a large set of customers and subsequently increases their knee cartilage repair market share in the MENA region.