The mRNA Synthesis Manufacturing Market is expected to register a CAGR of 5.8% from 2025 to 2031, with a market size expanding from US$ XX million in 2024 to US$ XX Million by 2031.
The report is segmented By Product (Consumables [Transcription, Purification, Analysis & Characterization], Instrument), Service (Synthesis, Purification, Manufacturing & Scale-up), Application (CGT, Vaccines). The global analysis is further broken-down at regional level and major countries. The Report Offers the Value in USD for the above analysis and segments.
Purpose of the ReportThe report mRNA Synthesis Manufacturing Market by The Insight Partners aims to describe the present landscape and future growth, top driving factors, challenges, and opportunities. This will provide insights to various business stakeholders, such as:
- Technology Providers/Manufacturers: To understand the evolving market dynamics and know the potential growth opportunities, enabling them to make informed strategic decisions.
- Investors: To conduct a comprehensive trend analysis regarding the market growth rate, market financial projections, and opportunities that exist across the value chain.
- Regulatory bodies: To regulate policies and police activities in the market with the aim of minimizing abuse, preserving investor trust and confidence, and upholding the integrity and stability of the market.
mRNA Synthesis Manufacturing Market Segmentation
Product- Consumables
- Instrument
- Synthesis
- Purification
- Manufacturing & Scale-up
- CGT
- Vaccines
Strategic Insights
mRNA Synthesis Manufacturing Market Growth Drivers- COVID-19 Vaccine Development: The success of mRNA-based COVID-19 vaccines has significantly accelerated the demand for mRNA synthesis manufacturing. These vaccines have demonstrated the effectiveness of mRNA technology, prompting increased investment in research and the expansion of manufacturing capabilities. This success has led to a broader acceptance and expansion of mRNA therapies for other diseases.
- Advancements in mRNA Therapeutics: The growth of mRNA therapeutics beyond vaccines is a major driver for the market. Companies are exploring mRNA for applications in cancer immunotherapies, gene editing, and protein replacement therapies. As the therapeutic potential of mRNA technology continues to expand, the need for efficient and scalable mRNA synthesis manufacturing will increase significantly.
- Increased Investment in Biotechnology: The growing interest and investment in biotechnology, particularly in gene-based therapies, is driving the mRNA synthesis manufacturing market. Governments, private investors, and pharmaceutical companies are investing heavily in the development of mRNA technologies, encouraging the establishment of more robust production facilities and increasing demand for high-quality mRNA synthesis capabilities for both research and commercial purposes.
- Rising Awareness of Hygiene and Infection Control: Increased awareness of hygiene and infection control, especially after the COVID-19 pandemic, is propelling the adoption of UVGI systems. These systems are gaining popularity in hospitals, schools, offices, and public spaces due to their ability to sterilize environments and prevent the spread of harmful microorganisms, making them a key component of infection prevention strategies.
- Technological Advancements in UVGI Systems: Advancements in UVGI technology, such as improved UV-C lamp efficiency and smarter control systems, are boosting the market. The development of more energy-efficient, durable, and user-friendly UVGI systems, along with better integration into HVAC systems, is enhancing their effectiveness in air and surface disinfection, driving their widespread adoption across various industries.
- Scale-Up of mRNA Production Facilities: A key trend is the rapid scale-up of mRNA production facilities to meet global demand. The increasing need for mRNA vaccines, therapeutics, and clinical trials has driven the establishment of large-scale manufacturing plants with advanced automation systems. This trend is crucial for ensuring the consistent and efficient production of high-quality mRNA at commercial scales.
- Focus on Raw Material Optimization: Manufacturers are focusing on optimizing raw materials for mRNA synthesis, including improving the quality and supply of nucleotides, lipids, and enzymes. By streamlining the production of these raw materials, companies can reduce costs and increase the efficiency of mRNA synthesis, ultimately driving market growth and making large-scale production more feasible.
- Integration of Automation and Digitalization: Automation and digital technologies are becoming increasingly important in the mRNA synthesis manufacturing market. Automated systems for synthesis, purification, and quality control are being integrated into manufacturing processes to improve efficiency, reduce human error, and ensure consistent product quality. This trend is pushing the industry toward more sustainable and cost-effective production practices.
- Emerging Applications in Personalized Medicine: The expansion of personalized medicine offers significant opportunities for mRNA synthesis manufacturers. As mRNA technology advances, it holds promise for tailored therapies based on an individual’s genetic profile. This could revolutionize the treatment of genetic disorders, cancers, and other diseases, providing a growing demand for bespoke mRNA production services.
- Collaboration with Pharmaceutical Companies: Partnerships between mRNA synthesis manufacturers and pharmaceutical companies create substantial growth opportunities. These collaborations allow manufacturers to meet the rising demand for mRNA-based drugs, vaccines, and treatments, further driving investments in production infrastructure and increasing the global reach of mRNA-based therapeutics.
- Expansion in Emerging Markets: Emerging markets present significant opportunities for mRNA synthesis manufacturing. As these regions experience rapid growth in healthcare infrastructure and biotechnology research, the demand for advanced mRNA production capabilities is expected to rise. Establishing local production facilities in these regions could help meet growing demands for mRNA-based vaccines and therapies while reducing supply chain costs.
Market Report Scope
Key Selling Points
- Comprehensive Coverage: The report comprehensively covers the analysis of products, services, types, and end users of the mRNA Synthesis Manufacturing Market, providing a holistic landscape.
- Expert Analysis: The report is compiled based on the in-depth understanding of industry experts and analysts.
- Up-to-date Information: The report assures business relevance due to its coverage of recent information and data trends.
- Customization Options: This report can be customized to cater to specific client requirements and suit the business strategies aptly.
The research report on the mRNA Synthesis Manufacturing Market can, therefore, help spearhead the trail of decoding and understanding the industry scenario and growth prospects. Although there can be a few valid concerns, the overall benefits of this report tend to outweigh the disadvantages.
REGIONAL FRAMEWORK
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- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
- Request discounts available for Start-Ups & Universities
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
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to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
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to country scope.
Frequently Asked Questions
Moderna, Inc., Pfizer Inc., BioNTech SE, CureVac AG, Arcturus Therapeutics, Genevant Sciences, Lonza Group, mRNA Technology Co., Ltd., Transcombi Therapeutics, Synthekine, Inc. are the some of the key market players operating in the mRNA synthesis manufacturing market
Asia Pacific is estimated to grow at the highest CAGR over the forecast year (2025 - 2031)
The North America region accounts for highest revenue share mRNA synthesis manufacturing market
The final report will duly include market size and projection estimates for all the segments from 2021 to 2031, along with a revenue share and compound annual growth rate (%) for the regional
/
country-wise market wherein 2021-2023 are the historic years, 2024 is considered to be the base year, and the forecast will be provided till 2031, along with CAGR (%)
The market is expected to grow at a CAGR of 5.8%
COVID-19 vaccine development and advancements in mRNA therapeutics are the major factors boosting the mRNA synthesis manufacturing market growth
- Moderna, Inc.
- Pfizer Inc.
- BioNTech SE
- CureVac AG
- Arcturus Therapeutics
- Genevant Sciences
- Lonza Group
- mRNA Technology Co., Ltd.
- Transcombi Therapeutics
- Synthekine, Inc.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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