The protein expression market in North America is expected to grow from US$ 872.9 million in 2021 to US$ 1,595.9 million by 2028; it is estimated to grow at a CAGR of 9.0% from 2021 to 2028.
The burden of dengue is rapidly increasing and will continue until the development of an effective vaccine against it. Various vaccine candidates for dengue are at preclinical and clinical trials stages of development based on different approaches. A few vaccines are a tetravalent, live attenuated virus, purified inactivated virus, recombinant proteins subunit, plasmid DNA, and virus-vectored dengue vaccines. Recent progress on recombinant subunit-based dengue vaccine candidates using various approaches, such as fusion with other immunogenic epitopes, use of a novel adjuvant, protein expression in different host systems, designer vaccine, and VLPs development, is opening new avenues for the development of a fully efficacious vaccine against dengue. Currently, more than 65 million confirmed cases and over 1.5 million deaths are reported. The COVID-19 pandemic has led to significant health, social, and economic crises. The development of a vaccine for COVID-19 is an effective strategy to control the outbreak. It is required that the vaccine is produced at high speed and is easily scalable. Recombinant protein, viral-vectored or nucleic acid-based (recombinant plasmid DNA and mRNA) vaccines need to be considered to shorten the vaccine production timeframe. The use of protein expression is increasing during vaccine development due to the advantages of recombinant protein, which drives the growth of the protein expression market
As the current pandemic is demonstrating across the region, the pharma industry can respond robustly to the health crisis but at a cost that society may not be able to sustain under current bioprocessing development and manufacturing models. Centuries of detecting, responding, and treating pandemics have taught that if a virus (or any biologic threat) is extremely infectious and transmittable, it can spread quickly and propagate in vast numbers of people, quickly jumping social distance, borders and the ability of healthcare systems to treat the sick. The way vaccines are developed and rolled out today is about the same as it has been for the past several decades. Currently, the region mainly relies on Chinese Hamster Ovary (CHO) cells or insect cells for expression as the gold standard, but its expense and processing complexity is driving developers to consider emerging cell line (hosts in which to express these proteins and vaccines) alternatives. To help combat the Covid-19 outbreak Dyadic International, Inc. developed a hyper productive C1 cell line that produces a SARS-CoV-2 Receptor Binding Domain (RBD) antigen from the Dyadic C1 gene expression platform that expresses the RBD antigen at three grams per liter (3.5 g/l) in only four days. The impact of the COVID19 pandemic on the regional protein expression market is high.
With the new features and technologies, vendors can attract new customers and expand their footprints in emerging markets. This factor is likely to drive the protein expression market. The North America protein expression market is expected to grow at a good CAGR during the forecast period.
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North America Protein Expression Market Segmentation
By Product
- Competent Cells
- Expression Vectors
- Reagents
- Instruments
By Services
- Antibody Development & Production
- Protein Expression & Production
- Hybridoma One-Stop Services
- Stable Cell Line Development
- Bioanalytical Assay Services
By Application
- Research
- Therapeutic
- Industrial
By End User
- Pharmaceutical and Biotechnology Companies
- Contract Research Organizations
- Academic Research Institutes
- Others
By Country
North America
- US
- Canada
- Mexico
Companies Mentioned
- Thermo Fisher Scientific Inc.
- GenScript
- Merck KGaA
- Agilent Technologies, Inc.
- Takara Bio Inc.
- Bio-Rad Laboratories Inc.
- QIAGEN
- New England Biolabs
- Promega Corporation
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
1. Introduction
1.1 Scope of the Study
1.2 The Insight Partners Research Report Guidance
1.3 Market Segmentation
1.3.1 Protein Expression Market – By Product
1.3.2 Protein Expression Market – By Services
1.3.3 Protein Expression Market – By Application
1.3.4 Protein Expression Market – By End User
1.3.5 North America Protein Expression Market – By Country
2. North America Protein Expression Market – Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. North America Protein Expression Market – Market Landscape
4.1 Overview
4.2 PEST Analysis
4.2.1 Protein Expression Market- North America PEST Analysis
4.3 Expert Opinion
5. North America Protein Expression Market - Key Market Dynamics
5.1 Market Drivers
5.1.1 Increasing Applications of Protein Expression
5.1.2 Growing Adoption of Precision Medicines
5.2 Market Restraints
5.2.1 High Cost of Products
5.3 Market Opportunities
5.3.1 Growing Funding for Genomics and Proteomics Research
5.4 Future Trends
5.4.1 Growing Traction Toward Recombinant Proteins
5.5 Impact Analysis
6. Protein Expression Market – North America Analysis
6.1 North America Protein Expression Market Revenue Forecasts and Analysis
7. North America Protein Expression Market Analysis and Forecasts To 2028 – By Product
7.1 Overview
7.2 Protein Expression Market Share, by Product, 2020 and 2028 (%)
7.3 Instruments
7.3.1 Overview
7.3.2 Instruments: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
7.4 Reagents
7.4.1 Overview
7.4.2 Reagents: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
7.5 Expression Vectors
7.5.1 Overview
7.5.2 Expression Vectors: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
7.6 Competent Cells
7.6.1 Overview
7.6.2 Competent Cells: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
8. North America Protein Expression Market Analysis and Forecasts To 2028 – By Services
8.1 Overview
8.2 Protein Expression Market Share, by Services, 2020 and 2028 (%)
8.3 Antibody Development & Production
8.3.1 Overview
8.3.2 Antibody Development & Production: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
8.4 Protein Expression & Production
8.4.1 Overview
8.4.2 Protein Expression & Production: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
8.5 Hybridoma One-Stop Services
8.5.1 Overview
8.5.2 Hybridoma One-Stop Services: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
8.6 Stable Cell Line Development
8.6.1 Overview
8.6.2 Stable Cell Line Development: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
8.7 Bioanalytical Assay Services
8.7.1 Overview
8.7.2 Bioanalytical Assay Services: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
9. North America Protein Expression Market Analysis and Forecasts To 2028 – By Application
9.1 Overview
9.2 Protein Expression Market Share, by Application, 2020 and 2028 (%)
9.3 Research
9.3.1 Overview
9.3.2 Research: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
9.4 Therapeutics
9.4.1 Overview
9.4.2 Therapeutics: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
9.5 Industrial
9.5.1 Overview
9.5.2 Industrial: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
10. Protein Expression Market Analysis – By End User
10.1 Overview
10.2 Protein Expression Market Share, by End User, 2020 and 2028 (%)
10.3 Pharmaceutical and Biotechnology Companies
10.3.1 Overview
10.3.2 Pharmaceutical and Biotechnology Companies: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
10.4 Academic Research Institutes
10.4.1 Overview
10.4.2 Academic Research Institutes: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
10.5 Contract research organizations
10.5.1 Overview
10.5.2 Contract research organizations: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
10.6 Others
10.6.1 Overview
10.6.2 Others: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
11. Protein Expression Market Revenue and Forecasts to 2028 – Geographical Analysis
11.1 North America: Protein Expression Market
11.1.1 Overview
11.1.2 North America: Protein Expression Market, by Country, 2021 & 2028 (%)
11.1.2.1 US: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
11.1.2.1.1 US: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
11.1.2.1.2 US Protein Expression Market, by Product – Revenue and Forecast to 2028 (USD Million)
11.1.2.1.3 US: Protein Expression Market, by Services – Revenue and Forecast to 2028 (USD Million)
11.1.2.1.4 US: Protein Expression Market, by Application – Revenue and Forecast to 2028 (USD Million)
11.1.2.1.5 US: Protein Expression Market, by End User – Revenue and Forecast to 2028 (USD Million)
11.1.2.2 Canada: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
11.1.2.2.1 Canada: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
11.1.2.2.2 Canada Protein Expression Market, by Product – Revenue and Forecast to 2028 (USD Million)
11.1.2.2.3 Canada Protein Expression Market, by Services – Revenue and Forecast to 2028 (USD Million)
11.1.2.2.4 Canada Protein Expression Market, by Application – Revenue and Forecast to 2028 (USD Million)
11.1.2.2.5 Canada Protein Expression Market, by End User – Revenue and Forecast to 2028 (USD Million)
11.1.2.3 Mexico: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
11.1.2.3.1 Mexico: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
11.1.2.3.2 Mexico Protein Expression Market, by Product – Revenue and Forecast to 2028 (USD Million)
11.1.2.3.3 Mexico Protein Expression Market, by Services – Revenue and Forecast to 2028 (USD Million)
11.1.2.3.4 Mexico Protein Expression Market, by Application – Revenue and Forecast to 2028 (USD Million)
11.1.2.3.5 Mexico Protein Expression Market, by End User – Revenue and Forecast to 2028 (USD Million)
12. Impact Of COVID-19 Pandemic on North America Protein Expression Market
12.1 North America: Impact Assessment of COVID-19 Pandemic
13. Industry Landscape
13.1 Overview
13.2 Developments Done By Companies
14. Company Profiles
14.1 THERMO FISHER SCIENTIFIC INC.
14.1.1 Key Facts
14.1.2 Business Description
14.1.3 Products and Services
14.1.4 Financial Overview
14.1.5 SWOT Analysis
14.1.6 Key Developments
14.2 GenScript
14.2.1 Key Facts
14.2.2 Business Description
14.2.3 Products and Services
14.2.4 Financial Overview
14.2.5 SWOT Analysis
14.2.6 Key Developments
14.3 MERCK KGaA
14.3.1 Key Facts
14.3.2 Business Description
14.3.3 Products and Services
14.3.4 Financial Overview
14.3.5 SWOT Analysis
14.3.6 Key Developments
14.4 Agilent Technologies, Inc.
14.4.1 Key Facts
14.4.2 Business Description
14.4.3 Products and Services
14.4.4 Financial Overview
14.4.5 SWOT Analysis
14.4.6 Key Developments
14.5 Takara Bio Inc.
14.5.1 Key Facts
14.5.2 Business Description
14.5.3 Products and Services
14.5.4 Financial Overview
14.5.5 SWOT Analysis
14.5.6 Key Developments
14.6 BIO-RAD LABORATORIES INC.
14.6.1 Key Facts
14.6.2 Business Description
14.6.3 Products and Services
14.6.4 Financial Overview
14.6.5 SWOT Analysis
14.6.6 Key Developments
14.7 QIAGEN
14.7.1 Key Facts
14.7.2 Business Description
14.7.3 Products and Services
14.7.4 Financial Overview
14.7.5 SWOT Analysis
14.7.6 Key Developments
14.8 New England Biolabs
14.8.1 Key Facts
14.8.2 Business Description
14.8.3 Products and Services
14.8.4 Financial Overview
14.8.5 SWOT Analysis
14.8.6 Key Developments
14.9 Promega Corporation
14.9.1 Key Facts
14.9.2 Business Description
14.9.3 Products and Services
14.9.4 Financial Overview
14.9.5 SWOT Analysis
14.9.6 Key Developments
15. Appendix
15.1 About the Insight Partners
15.2 Glossary of Terms
LIST OF TABLES
Table 1. US Protein Expression Market, by Product – Revenue and Forecast to 2028 (USD Million)
Table 2. US Protein Expression Market, by Services - Revenue and Forecast to 2028 (USD Million)
Table 3. US Protein Expression Market, by Application - Revenue and Forecast to 2028 (USD Million)
Table 4. US Protein Expression Market, by End User- Revenue and Forecast to 2028 (USD Million)
Table 5. Canada Protein Expression Market, by Product -Revenue and Forecast to 2028 (USD Million)
Table 6. Canada Protein Expression Market, by Services – Revenue and Forecast to 2028 (USD Million)
Table 7. Canada Protein Expression Market, by Application – Revenue and Forecast to 2028 (USD Million)
Table 8. Canada Protein Expression Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 9. Mexico Protein Expression Market, by Product -Revenue and Forecast to 2028 (USD Million)
Table 10. Mexico Protein Expression Market, by Services – Revenue and Forecast to 2028 (USD Million)
Table 11. Mexico Protein Expression Market, by Application – Revenue and Forecast to 2028 (USD Million)
Table 12. Mexico Protein Expression Market, by End User – Revenue and Forecast to 2028 (USD Million)
Table 13. Glossary of Terms, Protein Expression Market
LIST OF FIGURES
Figure 1. Protein Expression Market Segmentation
Figure 2. North America Protein Expression Market Overview
Figure 3. Reagents Segment Held Largest Share of Product in Protein Expression Market
Figure 4. US is Expected to Show Remarkable Growth During the Forecast Period
Figure 5. Protein Expression Market - North America PEST Analysis
Figure 6. Protein Expression Market Impact Analysis of Driver and Restraints
Figure 7. North America Protein Expression Market – Revenue Forecasts and Analysis – 2020- 2028
Figure 8. Protein Expression Market Share, by Product, 2020 and 2028 (%)
Figure 9. Instruments: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 10. Reagents: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 11. Expression Vectors: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 12. Competent Cells: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 13. Protein Expression Market Share, by Services, 2020 and 2028 (%)
Figure 14. Antibody Development & Production: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 15. Protein Expression & Production: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 16. Hybridoma One-Stop Services: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 17. Stable Cell Line Development: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 18. Bioanalytical Assay Services: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 19. Protein Expression Market Share, by Application, 2020 and 2028 (%)
Figure 20. Research: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 21. Therapeutics: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 22. Industrial: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 23. Protein Expression Market Share, by End User, 2020 and 2028 (%)
Figure 24. Pharmaceutical and Biotechnology Companies: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 25. Academic Research Institutes: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 26. Contract research organizations: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 27. Others: Protein Expression Market– Revenue and Forecast to 2028 (USD Million)
Figure 28. North America: Protein Expression Market, by Key Country – Revenue (2021) (USD Million)
Figure 29. North America: Protein Expression Market, by Country, 2021 & 2028 (%)
Figure 30. US: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
Figure 31. Canada: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
Figure 32. Mexico: Protein Expression Market – Revenue and Forecast to 2028 (USD Million)
Figure 33. Impact of COVID-19 Pandemic in North American Country Markets
- Thermo Fisher Scientific Inc.
- GenScript
- Merck KGaA
- Agilent Technologies, Inc.
- Takara Bio Inc.
- Bio-Rad Laboratories Inc.
- QIAGEN
- New England Biolabs
- Promega Corporation
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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