全外显子组测序市场基于(关键地区、市场参与者、规模和份额)- 到 2031 年的预测

  • Report Code : TIPRE00005519
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 178
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2018年整个外显子组测序市场价值为7.5568亿美元,预计2027年将达到38.120亿美元;预计 2019 年至 2027 年复合年增长率为 19.8%。

全外显子组是一种基因组技术,用于对基因的所有蛋白质编码区域进行测序一个基因组。全外显子组测序 (WES) 可供寻求多种疾病统一诊断的患者使用。使用外显子组富集的外显子组测序可以有效地检测多种应用中的编码变异,包括群体遗传学、遗传疾病和癌症研究。全球全外显子组测序市场的增长归因于测序时间和成本的减少、分子诊断需求的增加以及药物发现中应用的增加。然而,全外显子组测序的伦理、社会和法律问题以及高技能专业人员的缺乏是阻碍市场增长的主要因素。

全球全外显子组测序市场预计疫情过后将出现大幅增长。由于封锁、旅行禁令和企业关闭,COVID-19 已经影响了各国的经济和行业。 COVID-19 危机使许多国家的公共卫生系统负担过重,凸显了对卫生系统可持续投资的强烈需求。随着 COVID-19 大流行的进展,医疗保健行业的增长预计将下降。由于体外诊断产品需求的增加以及全球研发活动的增加,生命科学领域蓬勃发展。然而,由于进行的手术数量减少以及设备采购推迟或延长,医疗技术和成像领域的销售额正在下降。此外,医疗保健专业人员的虚拟咨询预计将成为大流行后的主流护理服务模式。随着远程医疗改变医疗服务方式,数字医疗将在未来几年继续蓬勃发展。此外,临床试验的中断以及随后药物上市的延迟预计也将为未来的完全虚拟试验铺平道路。 mRNA 等新技术预计将出现并改变制药行业,未来几年市场预计还将出现更多的垂直整合和合资企业。

全球全外显子组测序市场利润丰厚的区域


< p>市场洞察

减少测序时间和成本,推动全球全外显子组测序市场增长

外显子是基因组的一部分,负责制造 1% 或 2% 的基因组。一个人的整个基因组。基因组中的所有外显子统称为外显子组。因此,这些测序被称为全外显子组测序。与同时对几个基因进行测序相比,全外显子组测序可以识别任何基因的蛋白质编码位点的变异。全外显子组测序因其识别单个外显子突变的特性而受到广泛青睐。识别原始位点的突变使全外显子组测序成为一种有效的方法,并能够识别可能的致病突变。

基因组学领域的进步导致基因组测序的时间和成本显着减少。使用不同测序技术和策略进行测序的相关成本令人感兴趣,因为它们影响基因组研究的范围和规模。因此,它使得全外显子组测序比全基因组测序更受欢迎。

外显子组测序的优势导致很大程度上减少了时间和成本。大约2%的基因组通过WES方法进行测序;然而,它通常在更深层次上对外显子进行测序,其测序深度为 100X。该技术通过 DNA 和 RNA 与蛋白质编码位点杂交并与非编码位点分离的过程实现测序。此外,100X 测序所需的数据约为 5-6GB,而基因组测序则接近 90GB。因此,这些因素提供了更低的数据存储、更快、更便宜且更易于访问的数据分析。因此,由于上述因素,预计全外显子组测序市场在预测期内可能会大幅增长。

产品与技术基于服务的见解

在产品和服务方面服务方面,全球整个外显子组测序市场分为系统、试剂盒和服务。 2018年,套件细分市场占据最大份额。此外,预计同一细分市场在预测期内的复合年增长率最高。

全球全外显子组测序市场(按产品和领域划分)服务—— 2018年和2027年


基于技术的洞察

基于技术,全球全外显子组测序市场分为合成测序、离子半导体测序和其他技术。合成测序细分市场在 2018 年占据最大的市场份额,预计该细分市场在预测期内将以最快的速度增长。

基于应用的见解< /p>

在应用方面,全球全外显子组测序市场分为诊断、药物发现和开发、个性化医疗等。 2018年,诊断领域占据最大的市场份额。然而,药物发现和开发领域预计在预测期内复合年增长率最高。

战略见解

全球全外显子组测序市场参与者正在采取产品推出和扩张策略来满足全球不断变化的客户需求,这也使他们能够在全球范围内保持自己的品牌声誉。

全球全外显子组测序市场–按产品和服务

  • 系统
  • 试剂盒
  • 服务
  • 测序服务
  • 数据分析(生物信息学)
  • 其他服务

全球全外显子组测序市场 -按技术划分

  • 合成测序
  • 离子半导体测序
  • 其他技术

全球全外显子组测序市场–按应用分类

  • 诊断
  • 癌症诊断
  • 单基因(孟德尔)疾病诊断
  • 单基因糖尿病诊断的类型
  • 艾滋病毒诊断
  • 其他诊断
  • 药物发现与治疗开发
  • 个性化医疗
  • 其他

全球全外显子组测序市场 -按地理位置

  • 北美洲
    • 美国
    • 加拿大
    • 墨西哥
  • < li>欧洲
    • 法国
    • 德国
    • 意大利
    • 英国
    • 西班牙
    • 休息欧洲
  • 亚太地区 (APAC)
    • 中国
    • 印度
    • 韩国
    • 日本
    • 澳大利亚
    • 亚太地区其他地区
  • 中东和非洲非洲 (MEA)
    • 南非
    • 沙特阿拉伯
    • 阿联酋
    • 中东和非洲其他地区
  • 南美洲和中美洲 (SCAM)
    • 巴西
    • 阿根廷
    • 其他 SCAM
  • < /ul>

    公司简介

    • Thermo Fisher Scientific Inc.
    • Illumina, Inc.
    • Centogene AG
    • F. Hoffmann-La Roche AG
    • Psomagen, Inc.(原 Macrogen Corp.)
    • Pacific Biosciences of California, Inc.
    • Brooks Automation, Inc.(GENEWIZ , Inc.)
    • Bio-Rad Laboratories, Inc.
    • Eurofins Scientific
    • Stratos Genomics
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

The List of Companies

  1. Thermo Fisher Scientific Inc.
  2. Illumina, Inc.
  3. Centogene AG
  4. F. Hoffmann-La Roche AG
  5. Psomagen, Inc. (previuosly Macrogen Corp.)
  6. Pacific Biosciences of California, Inc.
  7. Brooks Automation, Inc. (GENEWIZ, Inc.)
  8. Bio-Rad Laboratories, Inc.
  9. Eurofins Scientific
  10. Stratos Genomics

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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