Le marché du séquençage à lecture longue était évalué à 1 101,15 millions de dollars US en 2020 et devrait atteindre 5 334,68 millions de dollars US d'ici 2028 ; il devrait croître à un TCAC de 22,3 % au cours de la période 2021-2028.
Le séquençage à lecture longue est une technique de séquençage de l'ADN. Il offre de nombreux avantages distincts par rapport aux technologies de séquençage de nouvelle génération, telles que le séquençage plus précis de l'ADN contenant les mêmes sections d'ADN répétées dans le génome. De nombreux adultes âgés de 60 ans et plus souffrent de deux maladies chroniques ou plus. Les gènes jouent un rôle dans les maladies chroniques telles que les maladies cardiovasculaires, le diabète, l'obésité, la polyarthrite rhumatoïde, la maladie d'Alzheimer (MA) et la dépression, selon une recherche jumelle. Selon les Centers for Disease Control and Prevention (CDC), environ 6 personnes sur 10 aux États-Unis sont touchées par au moins une maladie chronique, ainsi que 4 sur 10 souffrent de deux maladies chroniques ou plus. De plus, le cancer est principalement causé par des erreurs génomiques. Les chercheurs ont analysé les génomes du cancer à l'aide de diverses technologies de séquençage en évolution rapide afin de mieux comprendre l'état moléculaire des cellules cancéreuses et d'exposer leurs vulnérabilités telles que les mutations motrices ou l'expression des gènes. Les chercheurs ont pu reconnaître et classer de nouvelles formes de mutations cancéreuses à l'aide de technologies à lecture longue, y compris des variantes structurelles complexes dans la résolution des haplotypes. Ces dernières années, plusieurs technologies de séquençage à lecture longue ont été développées et utilisées. Par exemple, Pacific Biosciences a développé le séquençage SMRT, qui est l'une des méthodes de lecture longue (PacBio). Le séquençage à lecture longue devient de plus en plus courant, et les études sur le cancer basées sur des données à lecture longue se multiplient et progressent afin de décoder les génomes complexes du cancer.
Régions lucratives pour le marché du séquençage à lecture longue
Perspectives du marché : les avantages du séquençage à lecture longue stimulent le marché du séquençage à lecture longue
Les technologies à lecture longue surmontent les premières limitations de précision et de débit et montent leur application dans les domaines de génomique. Le séquençage à lecture longue ou séquençage de troisième génération offre plusieurs avantages par rapport au séquençage à lecture courte. Alors que les séquenceurs à lecture courte tels que les instruments HiSeq, NovaSeq, NextSeq et MiSeq d'Illumina, les modèles MGISEQ et BGISEQ de BGI ; ou les séquenceurs Ion Torrent de Thermo Fisher produisent des lectures allant jusqu'à 600 bases, les technologies de séquençage à lecture longue génèrent régulièrement des lectures supérieures à 10 kb. En outre, le séquençage à lecture longue des molécules natives, c'est-à-dire l'ADN et l'ARN, élimine le biais d'amplification tout en préservant les modifications de base. Avec des progrès continus en termes de précision, de débit et de réduction des coûts, ces capacités ont commencé à faire du séquençage à lecture longue une option pour un large éventail d'applications en génomique pour les organismes modèles et non modèles.
Technologie : Insights
Le marché mondial du séquençage à lecture longue, basé sur la technologie, est segmenté en séquençage en temps réel d'une seule molécule (SMRT), séquençage des nanopores et séquençage à lecture longue de la génomique en boucle. Le segment du séquençage en temps réel d'une seule molécule (SMRT) détenait la plus grande part du marché en 2020. Cependant, le segment du séquençage à lecture longue de la génomique en boucle devrait enregistrer le TCAC le plus élevé du marché au cours de la période de prévision.
< br />Marché du séquençage à lecture longue, par technologie - 2020 et 2028
Produit : en fonction du produit, le marché mondial du séquençage à lecture longue est segmenté en instruments, consommables , Et services. Le segment des instruments détenait la plus grande part du marché en 2020, et le segment des services devrait enregistrer le TCAC le plus élevé de 2021 à 2028.
Application : sur la base de l'application, le marché mondial du séquençage à lecture longue est segmenté en identification et cartographie fine de la variation structurelle, séquençage répété en tandem, discrimination des pseudogènes, résolution du phasage allélique, génomique reproductive, cancer, séquençage viral et microbien, etc. Le segment de l'identification et de la cartographie fine des variations structurelles détenait la plus grande part du marché en 2020, et le segment du cancer devrait enregistrer le TCAC le plus élevé de 2021 à 2028. Le marché est segmenté en pré-séquençage, séquençage et analyse de données. Le segment de séquençage détenait la plus grande part du marché en 2020, et le même segment devrait enregistrer le TCAC le plus élevé de 2021 à 2028.
Utilisateur final : en fonction de l'utilisateur final, le marché mondial du séquençage à lecture longue est segmenté en instituts de recherche universitaires, hôpitaux et cliniques, et sociétés pharmaceutiques et biotechnologiques. Le segment des instituts de recherche universitaires détenait la plus grande part du marché en 2020, et le même segment devrait enregistrer le TCAC le plus élevé au cours de la période 2021-2028.
Insights stratégiques
Acteurs opérant à long terme Le marché du séquençage de lecture adopte des stratégies de collaboration et de partenariat pour répondre aux demandes des utilisateurs finaux grâce à l'introduction d'offres technologiquement avancées, et ces stratégies soutiennent de manière significative la croissance du marché.
Par technologie
- Séquençage en temps réel d'une seule molécule (SMRT)
- Séquençage de nanopores
- Séquençage à lecture longue en boucle génomique
< ul>
Par application
- Identification et cartographie fine des variations structurelles
- Séquençage répété en tandem
- Discrimination pseudogène
- Résolution du phasage allélique
- Génomique reproductive
- Cancer < li>Séquençage viral et microbien
- Autres
- Pré-séquençage
- Séquençage < li>Analyse des données
- Instituts de recherche universitaires
- Hôpitaux et cliniques
- Entreprises pharmaceutiques et biotechnologiques< /li>
- Amérique du Nord
- États-Unis
- Canada
- Mexique
- Europe
- France
- Allemagne
- Italie
- Royaume-Uni
- Espagne< /li>
- Asie-Pacifique
- Chine
- Inde
- Corée du Sud
- Japon
- Australie
- Moyen-Orient et Afrique
- Afrique du Sud
- Arabie saoudite
- EAU
- Amérique du Sud et centrale
- Brésil
- Argentine
- Oxford Nanopore Technologies
- Tataa Biocenter
- Illumina, Inc
- Perkinelmer Inc.
- F. Hoffmann-La Roche Ltd.
- Baseclear BV
- Bionano Genomics
- Longas Technologies
- Pacific Biosciences of California, Inc.
- Quantapore, Inc.
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
Oxford Nanopore Technologies; Tataa Biocenter; Illumina, Inc; Perkinelmer Inc.; F. Hoffmann-La Roche Ltd.; and among others are major companies operating in this market.
The global long read sequencing market is being driven by factors such as advantages of long read sequencing and increasing prevalence of chronic diseases are likely to offer significant opportunities for the growth of the global long read sequencing market.
The dearth of skilled professionals is the significant factor that will hinder the long read sequencing market growth.
The List of Companies - Long Read Sequencing Market
- Illumina, Inc.
- Oxford Nanopore Technologies
- TATAA Biocenter
- PerkinElmer, Inc.
- F. HOFFMANN-LA ROCHE LTD.
- BaseClear B.V.
- Bionano Genomics
- Longas Technologies
- Pacific Biosciences of California, Inc.
- Quantapore, Inc.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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