Long Read Sequencing Market to Grow at a CAGR of 22.3% to reach US$ 5,334.68 million from 2020 to 2028

Long Read Sequencing Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Technology (Single-Molecule Real-Time Sequencing (SMRT), Nanopore Sequencing, Loop Genomics Long Read Sequencing), Product (Instruments, Consumables, Services), Application (Identification and fine mapping of structural variation, Tandem Repeat Sequencing, Pseudogene discrimination, Resolving allele phasing, Reproductive genomics, Cancer, Viral and Microbial Sequencing, Others), Workflow (Pre-sequencing, Sequencing, Data Analysis), End User (Academic Research Institutes, Hospitals and Clinics, Pharma and Biotechnology Companies) and Geography

  • Report Code : TIPRE00006815
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 125
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The long read sequencing market was valued at US$ 1,101.15 million in 2020 and it is projected to reach US$ 5,334.68 million by 2028; it is expected to grow at a CAGR of 22.3% during 2021–2028. 

The long read sequencing is a DNA sequencing technique. It offers numerous distinct advantages than next-generation sequencing technologies such as more precisely sequence DNA containing the same sections of DNA repeated within the genome. Many adults aged 60 years and above suffer from two or more chronic illnesses. Genes play a role in chronic diseases such as cardiovascular disease, diabetes, obesity, RA, Alzheimer's disease (AD), and depression, according to twin research. According to the Centers for Disease Control and Prevention (CDC), about 6 out of 10 individuals in the US are affected by at least one chronic disease, as well as 4 out of 10 are suffering from two or more chronic diseases. Furthermore, cancer is primarily caused by genomic errors. Researchers have analyzed cancer genomes using a variety of rapidly evolving sequencing technologies in order to better understand cancer cells' molecular status and expose their vulnerabilities such as driver mutations or gene expression. The researchers were able to recognize and classify new forms of cancerous mutations using long-read technologies, including complex structural variants in haplotype resolution. In recent years, several long read sequencing technologies have been developed and used. For example, Pacific Biosciences developed SMRT sequencing, which is one of the long read methods (PacBio). Long read sequencing is becoming more common, and cancer studies based on long read data are growing and advancing in order to decode complex cancer genomes.

Lucrative Regions for Long Read Sequencing Market

Lucrative Regions for Long Read Sequencing Market
  • Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.

Market Insights: Advantages of Long Read Sequencing Drives Long Read Sequencing Market

Long-read technologies are overcoming early limitations of accuracy and throughput and mounting their application in the fields of genomics. Long read sequencing or third-generation sequencing offers several advantages over short-read sequencing. While short-read sequencers such as Illumina’s HiSeq, NovaSeq, NextSeq, and MiSeq instruments, BGI’s MGISEQ and BGISEQ models; or Thermo Fisher’s Ion Torrent sequencers produce reads of up to 600 bases, long read sequencing technologies regularly generate reads over 10 kb Further, long reads can improve de novo assembly, mapping certainty, transcript isoform identification, and detection of structural variants. Also, long read sequencing of native molecules, i.e., DNA and RNA eliminates amplification bias while preserving base modifications. With continuing progress in accuracy, throughput, and cost reduction, these capabilities have begun to make long read sequencing an option for a broad range of applications in genomics for model and non-model organisms.


Technology:Insights

   
The global long read sequencing market, based on technology, is segmented into single-molecule real time sequencing (SMRT), nanopore sequencing, and loop genomics long read sequencing. The single-molecule real time sequencing (SMRT) segment held the largest share of the market in 2020. However, the loop genomics long read sequencing segment is expected to register the highest CAGR in the market during the forecast period.

Long Read Sequencing Market, by Technology – 2020 and 2028

Long Read Sequencing Market, by Technology – 2020 and 2028
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Product:Based on product, the global long read sequencing market is segmented into instruments, consumables, and services. The instruments segment held the largest share of the market in 2020, and the services segment is expected to register the highest CAGR during 2021–2028.
Application:Based on application, the global long read sequencing market is segmented into identification and fine mapping of structural variation, tandem repeat sequencing, pseudogene discrimination, resolving allele phasing, reproductive genomics, cancer, viral and microbial sequencing, and others. The identification and fine mapping of structural variation segment held the largest share of the market in 2020, and the cancer segment is expected to register the highest CAGR from 2021 to 2028.
Workflow:Based on workflow, the global long read sequencing market is segmented into pre-sequencing, sequencing, and data analysis. The sequencing segment held the largest share of the market in 2020, and the same segment is expected to register the highest CAGR during 2021–2028.
End-User:Based on end-user, the global long read sequencing market is segmented into academic research institutes, hospitals and clinics, and pharma and biotechnology companies. The academic research institutes segment held the largest share of the market in 2020, and the same segment is expected to register the highest CAGR during 2021–2028.


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Long Read Sequencing Market: Strategic Insights

long-read-sequencing-market
Market Size Value inUS$ 1,101.15 Million in 2020
Market Size Value byUS$ 5,334.68 Million by 2028
Growth rateCAGR of 22.3% from 2021-2028
Forecast Period2021-2028
Base Year2021
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Players operating in the long read sequencing market adopt collaboration and partnership strategies to meet the demands of end users through the introduction of technologically advanced offerings, and these strategies significantly support the growth of the market. 


By Technology 


  • Single-Molecule Real-Time Sequencing (SMRT)
  • Nanopore Sequencing
  • Loop Genomics Long Read Sequencing

By Product


  • Instruments
  • Consumables
  • Services

By Application


  • Identification and Fine Mapping of Structural Variation
  • Tandem Repeat Sequencing
  • Pseudogene Discrimination
  • Resolving Allele Phasing
  • Reproductive Genomics
  • Cancer
  • Viral and Microbial Sequencing
  • Others

By Workflow


  • Pre-sequencing
  • Sequencing
  • Data Analysis

By End User


  • Academic Research Institutes
  • Hospitals and Clinics
  • Pharma and Biotechnology Companies

By Geography


  • North America 

    • US
    • Canada
    • Mexico
  • Europe

    • France
    • Germany
    • Italy
    • UK
    • Spain
  • Asia Pacific 

    • China
    • India
    • South Korea
    • Japan
    • Australia
  • Middle East and Africa 

    • South Africa
    • Saudi Arabia
    • UAE
  • South and Central America

    • Brazil
    • Argentina

Company Profiles


  • Oxford Nanopore Technologies
  • Tataa Biocenter
  • Illumina, Inc
  • Perkinelmer Inc.
  • F. Hoffmann-La Roche Ltd.
  • Baseclear B.V.
  • Bionano Genomics
  • Longas Technologies
  • Pacific Biosciences of California, Inc.
  • Quantapore, Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Technology , Product , Application , Workflow , End User and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions


What are the major companies operated in this market?

Oxford Nanopore Technologies; Tataa Biocenter; Illumina, Inc; Perkinelmer Inc.; F. Hoffmann-La Roche Ltd.; and among others are major companies operating in this market.

What are the driving factors for the long read sequencing market across the globe?

The global long read sequencing market is being driven by factors such as advantages of long read sequencing and increasing prevalence of chronic diseases are likely to offer significant opportunities for the growth of the global long read sequencing market.

What are the restraining factors for the long read sequencing market across the globe?

The dearth of skilled professionals is the significant factor that will hinder the long read sequencing market growth.

The List of Companies - Long Read Sequencing Market

  1. Illumina, Inc.
  2. Oxford Nanopore Technologies
  3. TATAA Biocenter
  4. PerkinElmer, Inc.
  5. F. HOFFMANN-LA ROCHE LTD.
  6. BaseClear B.V.
  7. Bionano Genomics
  8. Longas Technologies
  9. Pacific Biosciences of California, Inc.
  10. Quantapore, Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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