mRNA Sequencing Market is expected to reach US$ 3,662.50 million by 2030

PRESS RELEASE BY The Insight Partners 16 Feb 2024

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Consumables Segment to Hold Significant mRNA Sequencing Market Size During 2022–2030

According to our latest study on "mRNA Sequencing Market Forecast to 2030 – Global Analysis – Type, Method, and End User," the market is expected to reach US$  3,662.50 million by 2030 from US$ 1,356.94 million in 2022. Factors such as the identification of mRNA sequencing for the diagnosis of rare diseases and innovative product launches propel the mRNA sequencing market growth.  

mRNA Sequencing in Drug Development Drives Market Growth

Drug discovery and development have undergone a remarkable transformation with the advent of single-cell RNA sequencing (scRNA-seq). scRNA-seq aids in the identification and validation of potential drug targets by characterizing the gene expression of individual disease cells. Therefore, by studying the transcriptomic profiles of healthy and diseased cells by scRNA-seq, researchers can identify specific cell types and identify disease progression. Also, the transcriptome information can guide in the selection of therapeutic target agents and help prioritize molecules for further development to provide valuable insights related to the action mechanism of drugs. Further, scRNA-seq can enable more accurate patient stratification and matching individuals with targeted therapies, thereby resulting in monitoring drug response and disease progression at the cellular level. Therefore, scRNA-seq will provide new market avenues for biotechnology companies to account for considerable revenue growth in terms of drug discovery and development in the coming years.


mRNA Sequencing Market Growth, Size, Share, Trends by 2030

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mRNA Sequencing Market Size and Forecasts (2020 - 2030), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Type (Products and Services), Method (First Generation Sequencing, Next Generation Sequencing, and Third Generation Sequencing), End User (Healthcare Facilities, Pharmaceutical and Biotechnology Companies, Clinical Research Organizations, and Others), and Geography (North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America)

Market Opportunity

Innovative Product Launches Through Strategic Developments by Key Manufacturers

Organic developments, such as product launches by the manufacturers, will likely bolster the mRNA sequencing market size in the coming years. In November 2023, the revolutionary LUTHOR High-Definition Single Cell 3' mRNA-Seq Kit was introduced by Lexogen, a trailblazer in the fields of transcriptomics and genomics. This ground-breaking invention raises the bar for single-cell RNA sequencing. The aforementioned factors are responsible for influential mRNA sequencing market growth in the coming years.

mRNA Sequencing Market, by Product:

Based on product, the mRNA sequencing market analysis is carried out by considering the following segments: products and services. The product segment is further classified into instruments and consumables. The consumables segment held the largest market share in 2022.

mRNA Sequencing Market, by Method: 

By method, the market is segmented as first-generation sequencing, next generation sequencing (NGS), and third-generation sequencing. The next generation sequencing (NGS) segment held the largest mRNA sequencing market share in 2022 and is anticipated to register the highest CAGR of 13.5% during the forecast period. NGS-based mRNA sequencing is a powerful method providing several advantages over traditional methods for transcriptome analysis. For example, NGS-based mRNA sequencing is a cost-effective process, including direct quantification and identification of transcripts and provides sensitive and accurate measurement of gene expression. Therefore, the cost-effectiveness of NGS-based mRNA sequencing is an influential factor responsible for segment growth during 2022–2030.

Market Trends

Exploring mRNA Sequencing Applications in Various Fields

mRNA sequencing has applications in single-cell sequencing for in-depth cellular investigation, spatial transcriptomics for mapping gene expression in tissues, and personalized medicine for customized treatments based on individual genetic profiles. mRNA sequencing requires the understanding of disease causes, finding biomarkers, and researching gene expression. By shedding light on intricate biological processes, mRNA sequencing is enhancing the fields of neuroscience, cancer immunotherapy, and infectious disease research.

Moreover, mRNA vaccines show great promise as a fast-developing, safe, and inexpensive alternative to traditional vaccination methods due to their high potency and possibility for safe administration. Numerous mRNA vaccination platforms against cancer and infectious diseases have shown promising outcomes in both animal models and humans. Thus, emerging applications will bring new mRNA sequencing market trends in the coming years. 

mRNA Sequencing Market, by Geography: 

The scope of the mRNA sequencing market report encompasses North America (the US, Canada, and Mexico), Europe (Spain, the UK, Germany, France, Italy, and the Rest of Europe), Asia Pacific (South Korea, China, India, Japan, Australia, and the Rest of Asia Pacific), Middle East & Africa (South Africa, Saudi Arabia, the UAE, and the Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and the Rest of South & Central America). In 2022, North America held the largest mRNA sequencing market share. The market growth in this region is driven by the presence of key market players. In addition, extensive R&D by various pharmaceutical and biotechnology companies and academic & research institutes positioned North America as a key region for the mRNA sequencing market growth in 2022.

Industry Developments and Future Opportunities:

The mRNA sequencing market forecast can help stakeholders in this marketplace plan their growth strategies. A few strategic developments by leading players operating in the market are listed below:

·         In May 2023, Twist Bioscience announced the launching of RNA sequencing tools that include the Twist RNA Exome, Twist RNA Library Prep Kit, and Twist Ribosomal RNA and Hemoglobin (Globin) Depletion Kit. The new product launch by the Twist RNA sequencing portfolio provides end-to-end workflows that can be used to study the total RNA and measure the whole transcriptome and protein-coding sequences of messenger RNA (mRNA) or custom targets. Also, these products can be integrated into customer's existing workflows and are compatible with a wide range of sample inputs, including difficult or low-quality samples.

·         In September 2023, Foundation Medicine, Inc. announced the launching of "FoundationOne RNA," intended for research use and investigational versions for its broad tissue-based RNA test. FoundationOne RNA intended for research use will be available for exploratory use in analyzing 318 genes for fusion detection by expanding capabilities to offer gene expression reporting of over 1,500 genes to support biomarker discovery.

Apart from factors driving the market, the mRNA sequencing market report emphasizes prominent players' developments. Takara Bio Inc.; Illumina, Inc.; QIAGEN; F. Hoffmann-La Roche Ltd; Quantabio, Zymo Research Corporation; baseclick GmbH; Paragon Genomics, Inc.; Yeasen Biotechnology (Shanghai) Co., Ltd.; Novogene Co, Ltd; and Norgen Biotek Corp are among the prominent players in operating in the market.

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