Europe Genome Editing Market to Reach US$ 3,421.1 Mn at CAGR of 16.7% in 2025 | The Insight Partners

Europe Genome Editing Market to 2025 - Regional Analysis and Forecasts by Technology (TALENS, CRISPR, Zinc Finger Nucleases (ZFNs), Antisense RNA and Others), Application (Genetic Engineering, Cell Line Engineering and Others) End User (Biotechnology & Pharmaceutical Companies, Contract Research Organizations (CROs), and Academic & Government Research Institutes), and Country

Publication Month: Apr 2019 | Report Code: TIPRE00003908 | No. of Pages: 145 | Category: Biotechnology | Status: Published

The Europe genome editing market accounted to US$ 1,052.9 Mn in 2017 and is expected to grow at a CAGR of 16.7% during the forecast period 2018 – 2025, to account to US$ 3,421.1 Mn by 2025.

The Asia Pacific genome editing market is expected to grow at highest rate during the forecast period owing to increasing investments by the governments of the respective countries in the region. In addition, the rise in the development and research for the genome editing along with the clinical trials are expected to fuel the market growth in Asia Pacific region.         

 

Exhibit: Lucrative Regional Markets

Market Insights

Rise in the Advancements for Genome Editing Technologies

The biotechnological field is characterized as a continuously developing the technologies for the betterment of the health for all the living organisms. Therefore, the technologies for the genome editing is undergoing various advancements, the most recent advancement for the genome editing is utilizing the nucleases which include the zinc finger nuclease (ZFN), transcription activators like effector nuclease (TALEN) and (clustered regulatory interspaced short palindromic repeats) CRISPR Cas9 system. The technologies has been successfully implemented in the several crops, including the Solanaceae plants, such as tomato, potato, tobacco, and petunia. CRISPR Case 9 among the three nucleases is the best for breeding, crop improvement, and the functional analysis of genes of interest. The technology is best due to its simplicity and high efficiency.

The technological advancements are being carried out by most of the biotechnological companies. The companies are continuously involved in the research and development for the technologies and producing the products for the genome editing. In addition, most of the start-up companies are involved in the development of the genome editing tools and services. For instance, UK based company, Horizon Discovery have discovered cell lines, the company has utilized the ability of the rAAV’s to amplify the cell's own high fidelity DNA repair pathway. The cell lines created consists of the precisely engineered, disease that are associated with mutations for the most widely studied oncology genes, such as KRAS, PIK3CA and BRAF. Moreover, the company is also license out its nuclease-based genome editing technologies to improve our efficiencies still further at first Zinc Finger Nucleases (ZFNs), and then CRISPR Cas9 gene editing. Thus, the technological advancement for genome editing tools by the market players and the start-up companies are likely to drive the market for the genome editing market in the forecast period.

 

European Court of Justice Ruling on Genome Editing

Recently, under the EU regulation on genetically modified organisms the judgment is passed through the European Court of Justice that gene-edited crops should be subjected to the same stringent regulations as conventional genetically modified (GM) organisms. In turn, the trial releases of plants and animals obtained by genome editing will also be subjected to the requirements of risk assessment and authorization. The EU Directive on the deliberate release into the environment of genetically modified organisms of 2001 (Directive 2001/18/EC), established a stringent system of control over the release and marketing of GMOs.  According to Article 2(2), a GMO is an organism in which the genetic material has been altered in a way that does not occur naturally by mating and/or natural recombination.

In this closely watched decision, the court ruled that plants that are created with new gene-editing techniques, which do not involve transferring genes between organisms such as CRISPR, subjected to go through the same lengthy approval process as traditional transgenic plants. This regulatory process typically costs about $35 million. On the other hand, the French government passed a law to release these new gene-edited crops from regulation under the European Union’s directive on genetically modified organisms (GMOs), which requires an assessment of risks to health and the environment, as well as labeling, tracking, and monitoring of the products. In addition, a French union in Bagnolet, Confédération Paysanne that represents small farms and eight other groups, sued and charged the plants modified with gene-editing techniques that it should be regulated under the GMO directive.

The products obtained by genome editing are also subjected to labelling requirements. On the other hand, small seed producers, including biotechnological start-up enterprises will expected to face difficulties in the coming years. The judgment can hamper the biotechnological research in Europe and it is going to impact plant breeding in Europe hugely and negatively.

 

Scopes for the Consumer Genomics

Biotechnology is wide industry which is comprised of the enormous group of application that has enabled researchers and scientists to evolve the healthcare services and facilities for the humans, animals and plants. The wide range of application has also helped most of the industries to introduce the biotechnological products for commercialization and has generated so much of revenue and innovated novel products that have benefited the producers and consumers. The major market is contributed through the genome editing and the technologies have enabled to diagnosed and treat various chronic diseases.

Genomics have made possible to conduct approximately 10 million genotyped customers and the consumer genomics industry is developing and likely to become a mainstream fundamental. In addition, the human genome project has motivated to increase the usage of the genomics. In addition, it has increased advertising expenditure by the market players and have decreased the cost of the genotyping. The genomics has enabled to create database of the people in various countries to study their health patterns and their history. In addition, growing advancements of genome editing are attracting more of people to sequence their genome to avoid future complications in their health.

 

Technology Insights

The genome editing market by technology is segmented as, transcription activator-like effector nucleases (TALENS), clustered regularly interspaced short palindromic repeats (CRISPR), zinc finger nucleases (ZFNs), antisense RNA and others. In 2017, the CRISPR segment held a largest market share of 53.6% of the genome editing market. This segment is also expected to dominate the market in 2025 owing to the simple, fast and accurate property of the CRISPR. Moreover, the TALENs segment is anticipated to witness the significant growth rate of 16.6% during the forecast period, 2018 to 2025 owing to the properties provided by the TALENs the market for it is expected to rise in the coming near future.

 

Application Insights

The Europe genome editing market on the basis of application is segmented into genetic engineering, cell line engineering and others. The cell line engineering segment is anticipated to grow at a CAGR of 17.5% during the forecast period. Moreover, the genetic engineering segment is expected to grow at the significant rate during the coming years owing to its sub segments such as animal genetic engineering and plant genetic engineering that are being carried out extensively.

 

End User Insights

The Europe genome editing market on the basis of end user is segmented into biotechnology & pharmaceutical companies, academic & government research organizations, and contract research organization. In 2017, biotechnology & pharmaceutical companies segment held the largest share of 61.2% of the end user market, and is expected to grow at the fastest rate during the coming years owing to the advantages of the CRISPR, the companies have enhanced their research and development for the drug discoveries that can treat various diseases. Hence, the market is likely to propel in the coming years.

 

Exhibit: Genome Editing Market, by End User

  

Strategic Insights

Strategic acquisition and product launches were observed as the most adopted strategy in Europe genome editing industry. Few of the recent product launch and product approval are listed below:

 

2018: Thermo Fisher Scientific announced the acquisition of IntegenX. IntegenX has been developing rapid DNA testing technology for human identification for use in forensics and law enforcement. The company in 2015, has launched RapidHIT System, which is the first-generation STR-based human identification system that is also compatible with Thermo Fisher's STR kits.

2017: Integrated DNA Technologies announced the product launch of variants of the first Cas9 enzyme. These are used for extensive reduction off-target effects in CRISPR genome editing and does not compromise on-target activity. The Alt-R S.p. HiFi Cas9 Nuclease 3NLS enzyme is a recombinant S. pyogenes Cas9 mutant improvises the specificity and also maintenance a high editing efficiency similar to wild-type Cas9.

2016: GenScript announced the launch of its new service CRISPR based Yeast Genome Editing Service. The service utilizes the λ Red-CRISPR/Cas9 technology.

 

EUROPE GENOME EDITING – MARKET SEGMENTATION

 

By Technology

  • TALENS
  • CRISPR
  • Zinc Finger Nucleases (ZFNs)
  • Others

 

By Application

  • Genetic Engineering
    • Animal Genetic Engineering
    • Plant Genetic Engineering
  • Cell Line Engineering
  • Others

 

By End User

  • Biotechnology & Pharmaceutical Companies
  • Contract Research Organizations (CROs)
  • Academic & Government Research Institutes

 

By Geography

•   Europe

  • U.S.
  • Canada
  • Mexico

 

Company Profiles

  • Transposagen Biopharmaceuticals, Inc.
  • Integrated DNA Technologies, Inc.
  • Thermo Fisher Scientific Inc.
  • GenScript
  • Lonza
  • Horizon Discovery Group plc
  • Sangamo Therapeutics, Inc.
  • New England Biolabs
  • Editas Medicine
  • Merck KGaA

PART 1.       iNTRODUCTION

1.1            Scope of the Study

1.2            The Insight Partners Research Report Guidance

PART 2.       Europe GENOME EDITING TESTING Market – Key takeaways

PART 3.       Europe genome editing market – market landscape

3.1            overview

3.2            market segmentation

3.2.1          Europe Genome Editing Market – By Technology

3.2.2          Europe Genome Editing Market – By Application

3.2.3          Europe Genome Editing Market – By End User

3.2.4          Europe Genome Editing Market – By Country

3.3            PEST Analysis

PART 4.       Europe genome editing market- Key Market Dynamics

4.1            Key Market Drivers

4.1.1          Rise in the Advancements For Genome Editing Technologies

4.1.2          Technological Developments in Genomics

4.2            Key Market Restraints

4.2.1          European Court of Justice Ruling on Genome Editing

4.2.2          Nonexistence of Skilled Professionals

4.3            Key Market Opportunities

4.3.1          Scopes for the Consumer Genomics

4.4            future Trends

4.4.1          Technologies of Gene Editing

4.5            Impact analysis

PART 5.       Genome Editing market – Europe Analysis

5.1            Europe GENOME EDITING market Revenue Forecasts and Analysis

5.2            Market positioning

5.3            PERFORMANCE OF KEY PLAYERS

5.4            expert opinions

PART 6.       Europe GENOME EDITING market Analysis – By Technology

6.1            Overview

6.2            EUrope GENOME EDITING MARKET, BY technology, 2017 & 2025 (%)

6.3            Europe GENOME EDITING market Revenue And Forecasts to 2025, By Technology (US$ Mn)

6.4            transcription activator-like effector nucleases (TALENS) Market

6.4.1          Overview

6.4.2          Europe Transcription Activator-Like Effector Nucleases (TALENS) Market Revenue and Forecasts to 2025 (US$ Mn)

6.5            clustered regularly interspaced short palindromic repeats (CRISPR) Market

6.5.1          Overview

6.5.2          Europe Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Market Revenue and Forecasts to 2025 (US$ Mn)

6.6            zinc finger nucleases (ZFNs) Market

6.6.1          Overview

6.6.2          Europe Zinc Finger Nucleases (ZFNs) Market Revenue and Forecasts to 2025 (US$ Mn)

6.7            Antisense RNA Market

6.7.1          Overview

6.7.2          Europe Antisense RNA Market Revenue and Forecasts to 2025 (US$ Mn)

6.8            Others Market

6.8.1          Overview

6.8.2          Europe Others Market Revenue and Forecasts to 2025 (US$ Mn)

PART 7.       Europe genome editing market Analysis – By Application

7.1            Overview

7.2            Europe GENOME EDITING MARKET, BY Application, 2017 & 2025 (%)

7.3            Europe GENOME EDITING market Revenue And Forecasts to 2025, By Application (US$ Mn)

7.4            Genetic Engineering Market

7.4.1          Overview

7.4.2          Europe Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

7.4.3          Animal Genetic Engineering Market

7.4.3.1      Overview

7.4.3.2      Europe Animal Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

7.4.4          Plant Genetic Engineering Market

7.4.4.1      Overview

7.4.4.2      Europe Plant Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

7.5            cell line engineering Market

7.5.1          Overview

7.5.2          Europe Cell Line Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

7.6            Others Market

7.6.1          Overview

7.6.2          Europe Others Market Revenue and Forecasts to 2025 (US$ Mn)

PART 8.       Europe genome editing market Analysis – By End User

8.1            Overview

8.2            Europe GENOME EDITING MARKET, BY end user, 2017 & 2025 (%)

8.3            Europe GENOME EDITING market Revenue And Forecasts to 2025, By end user (US$ Mn)

8.4            Biotechnology & pharmaceutical Companies Market

8.4.1          Overview

8.4.2          Europe Biotechnology & Pharmaceutical Companies Market Revenue and Forecasts to 2025 (US$ Mn)

8.5            ACADEMIC & GOVERNMENT RESEARCH ORGANIzATIONS Market

8.5.1          Overview

8.5.2          Europe Academic & Government Research Organizations Market Revenue and Forecasts to 2025 (US$ Mn)

8.6            Contract Research organization Market

8.6.1          Overview

8.6.2          Europe Contract Research Organization Market Revenue and Forecasts to 2025 (US$ Mn)

PART 9.       Europe genome editing market Revenue and Forecasts to 2025

9.1            Overview

9.2            Europe Genome Editing testing market Revenue and Forecasts to 2025 (US$ Mn)

9.3            Europe Genome editing Market Revenue And Forecasts to 2025, By technology (US$ Mn)

9.4            Europe Genome editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

9.4.1          Europe Genetic Engineering Market Revenue And Forecasts to 2025, By Type (US$ Mn)

9.5            Europe Genome editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

9.6            Europe Genome editing Market Revenue And Forecasts to 2025, By Country (%)

9.7            UK Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.7.1          UK Genome Editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.7.2          UK Genome Editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

9.7.3          UK Genome Editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

9.7.3.1      UK Genetic Engineering Market Revenue And Forecasts to 2025, By Type (US$ Mn)

9.7.4          UK Genome Editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

9.8            Germany Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.8.1          Germany Genome Editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.8.2          Germany Genome Editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

9.8.3          Germany Genome Editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

9.8.3.1      Germany Genetic Engineering Market Revenue And Forecasts to 2025, By Type (US$ Mn)

9.8.4          Germany Genome Editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

9.9            France Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.9.1          France Genome Editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.9.2          France Genome Editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

9.9.3          France Genome Editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

9.9.3.1      France Genetic Engineering Market Revenue And Forecasts to 2025, By Type (US$ Mn)

9.9.4          France Genome Editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

PART 10.    Genome Editing Market–Key company profiles

10.1         Thermo Fisher Scientific Inc.

10.1.1       Key Facts

10.1.2       Business Description

10.1.3       Financial Overview

10.1.4       Product Portfolio

10.1.5       SWOT Analysis

10.1.6       Key Developments

10.2         Integrated DNA Technologies, Inc.

10.2.1       Key Facts

10.2.2       Business Description

10.2.3       Financial Overview

10.2.4       Product Portfolio

10.2.5       SWOT Analysis

10.2.6       Key Developments

10.3         Merck Kgaa

10.3.1       Key Facts

10.3.2       Business Description

10.3.3       Financial Overview

10.3.4       Product Portfolio

10.3.5       SWOT ANALYSIS

10.3.6       KEY DEVELOPMENTS

10.4         Lonza

10.4.1       Key Facts

10.4.2       Business Description

10.4.3       Financial Overview

10.4.4       Product Portfolio

10.4.5       SWOT Analysis

10.4.6       Key Developments

10.5         New England Biolabs

10.5.1       Key Facts

10.5.2       Business Description

10.5.3       Financial Overview

10.5.4       Product Portfolio

10.5.5       SWOT Analysis

10.5.6       Key Developments

10.6         GenScript

10.6.1       Key Facts

10.6.2       Business Description

10.6.3       Financial Overview

10.6.4       Product Portfolio

10.6.5       SWOT Analysis

10.6.6       Key Developments

10.7         Transposagen Biopharmaceuticals, inc.

10.7.1       Key Facts

10.7.2       Business Description

10.7.3       Financial Overview

10.7.4       Product/ Services Portfolio

10.7.5       SWOT Analysis

10.7.6       Key Developments

10.8         Horizon Discovery Group Plc

10.8.1       Key Facts

10.8.2       Business Description

10.8.3       Financial Overview

10.8.4       Product/ Services Portfolio

10.8.5       SWOT Analysis

10.8.6       Key Developments

10.9         Sangamo Therapeutics, Inc.

10.9.1       Key Facts

10.9.2       Business Description

10.9.3       Financial Overview

10.9.4       Product Portfolio

10.9.5       SWOT Analysis

10.9.6       Key Developments

10.10      Editas MEdicine

10.10.1     Key Facts

10.10.2     Business Description

10.10.3     Financial Overview

10.10.4     Service Portfolio

10.10.5     SWOT Analysis

10.10.6     Key Developments

PART 11.    Appendix

11.1         About The Insight Partners

11.2         Glossary of Terms

11.3         Methodology

11.3.1       Coverage

11.3.2       Secondary Research

11.3.3       Primary Research


list of tables

TABLE 1.           Europe GENOME EDITING market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 2.           Europe GENOME EDITING market Revenue And Forecasts to 2025, By Application (US$ Mn)

TABLE 3.           Europe GENOME EDITING market Revenue And Forecasts to 2025, By end user (US$ Mn)

TABLE 4.           Europe Genome editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 5.           Europe Genome editing Market Revenue And Forecasts to 2025, By application (US$ Mn)

TABLE 6.           Europe genetic engineering Market Revenue And Forecasts to 2025, By type (US$ Mn)

TABLE 7.           Europe Genome editing Market Revenue And Forecasts to 2025, By end user (US$ Mn)

TABLE 8.           UK Genome editing Market Revenue And Forecasts to 2025, By technology (US$ Mn)

TABLE 9.           UK Genome editing Market Revenue And Forecasts to 2025, By application (US$ Mn)

TABLE 10.        Uk genetic engineering Market Revenue And Forecasts to 2025, By type (US$ Mn)

TABLE 11.        UK Genome editing Market Revenue And Forecasts to 2025, By End user (US$ Mn)

TABLE 12.        Germany Genome editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 13.        Germany Genome editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

TABLE 14.        Germany genetic engineering Market Revenue And Forecasts to 2025, By type (US$ Mn)

TABLE 15.        Germany Genome editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

TABLE 16.        France Genome editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 17.        France Genome editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

TABLE 18.        France genetic engineering Market Revenue And Forecasts to 2025, By type (US$ Mn)

TABLE 19.        France Genome editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

TABLE 20.        Glossary of Terms, GENOME EDITING market

list of figures

FIGURE 1.        Germany genome editing market, Revenue (US$ Mn), By COuntry 2018 & 2025

FIGURE 2.        Europe genome editing Market By Type, Market Share (%), 2017

FIGURE 3.        Europe genome editing Market By services, Market Share (%), 2017

FIGURE 4.        Europe genome editing Market By end user, Market Share (%), 2017

FIGURE 5.        genome editing market Segmentation

FIGURE 6.        Europe PEST Analysis

FIGURE 7.        genome editing market impact analysis of drivers & Restraints

FIGURE 8.        Europe GENOME EDITING market – Revenue Forecasts and Analysis – 2017- 2025

FIGURE 9.        Europe GENOME EDITING market, By technology, 2017 & 2025 (%)

FIGURE 10.     Europe transcription activator-like effector nucleases (TALENS) Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 11.     Europe Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 12.     Europe Zinc Finger Nucleases (ZFNs) Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 13.     Europe Antisense RNA Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 14.     Europe Others Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 15.     Europe GENOME EDITING market By Application, 2017 & 2025 (%)

FIGURE 16.     Europe Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 17.     Europe Animal Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 18.     Europe Plant Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 19.     Europe Cell Line Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 20.     Europe Others Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 21.     Europe GENOME EDITING market By end user, 2017 & 2025 (%)

FIGURE 22.     Europe Biotechnology & Pharmaceutical Companies Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 23.     Europe Academic & Government Research Organizations Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 24.     Europe Contract Research organization Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 25.     Europe genome editing market REVENUE overview, by Country, 2017 (US$ MN)

FIGURE 26.     Europe Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 27.     Europe Genome editing Market Revenue And Forecasts to 2025, By Country (%)

FIGURE 28.     UK genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 29.     Germany Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 30.     France Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

 

The List of Companies

  1. Transposagen Biopharmaceuticals, Inc.
  2. Integrated DNA Technologies, Inc.
  3. Thermo Fisher Scientific Inc.
  4. GenScript
  5. Lonza
  6. Horizon Discovery Group plc
  7. Sangamo Therapeutics, Inc.
  8. New England Biolabs
  9. Editas Medicine
  10. Merck KGaA
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