dPCR 和 qPCR 市场基于(关键地区、市场参与者、规模和份额)- 到 2030 年的预测

  • Report Code : TIPHE100000817
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 159
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【研究报告】dPCR和qPCR市场规模预计将从2022年的897,699万美元增长到2030年的1823,074万美元;预计 2022 年至 2030 年复合年增长率为 9.3%。
市场洞察和分析师观点:
定量 PCR (qPCR) 和数字 PCR (dPCR) 是 PCR 技术的两个主要类别。 dPCR 用于评估基因和细胞疗法的适当剂量,并检测癌症患者的循环肿瘤 DNA。 qPCR 在反应进行的同时计算 PCR 扩增。 dPCR 和 qPCR 是广泛应用于研究、制药和生物技术等不同领域的诊断技术,具有广泛的应用范围。 PCR 系统的技术进步以及对准确可靠的癌症生物标志物检测的需求不断增长,推动了对分子检测的需求不断增长。此外,人口对个性化医疗的需求不断增加、基因组学研究的改进以及传染病发病率的增加推动了 dPCR 和 qPCR 市场的增长。
增长动力:
根据国家组织有关遗传条件或疾病的信息先天性残疾,尽管个别遗传性疾病很少见,但总体而言,诊断患有遗传性疾病的人数超过 15,500 人。美国 MJH Life Sciences 的一份报告估计,到 2022 年,全球每年有 30 万新生儿患有镰状细胞病,约占全球人口的 5%。在美国,它是最普遍的遗传病之一。此外,据 CDC 称,每 500 名非裔美国人中就有 1 人患有镰状细胞病,其中约 12 人中就有 1 人患有常染色体隐性突变。 2020 年 6 月,根据诺华公司(瑞士)的报告,约有 15,000 人患有镰状细胞病,每年有 270 名新生儿被诊断出患有该病。此外,这种疾病在印度等新兴国家最为流行。在印度的部落社区中,约 1800 万人受到镰状细胞性状 (SCT) 的影响,140 万人患有镰状细胞病 (SCD)。数字 PCR 的采用正在不断进步,因为病理学家正在尝试跟踪该技术的使用,以针对各种特定 DNA 序列并诊断和设计各种临床测试。数字 PCR 可以仅针对一个 DNA 分子中的特定 DNA 序列。这一新工具使研究人员能够分离出难以通过实时 PCR 分离的罕见基因突变。
COVID-19 的爆发对聚合酶链式反应市场的增长产生了重大影响。临床诊断市场不断增长的需求对PCR行业产生了有利的影响。几乎所有诊断测试都使用 RT-PCR 来测试有 COVID-19 症状的人,并被医疗保健专家敦促进行诊断测试,而当局尚未认可病毒培养测试。大多数生物技术和制药企业都将精力集中在研发部门,寻找针对 COVID-19 的新化合物或治疗方法。 2022年2月,罗氏将新发布的分子实验室仪器Cobas 5800系统添加到其COVID-19 PCR产品组合中,供接受CE认证的国家使用。这些产品包括cobas SARS-CoV-2和甲型/乙型流感检测,以及cobas SARS-CoV-2定性检测。通过在低、中和高容量分子实验室测试需求中提供统一的性能和效率,这些产品拓宽了罗氏诊断的分子产品组合。此外,借助新型紧凑型 Cobas 5800 系统,空间或资源有限的医疗保健组织可以进行全面访问。在由于缺乏资源或空间而无法容纳较大设备的国家或地区,将获得更好的测试可及性。
因此,可以使用 dPCR 和 qPCR 技术进行诊断的遗传性疾病和传染病的发病率不断增加和治疗推动了 dPCR 和 qPCR 市场的增长。
战略见解
报告细分和范围:
dPCR 和 qPCR 市场根据治疗、产品、应用、最终用户和地理位置进行细分。根据处理方式,dPCR 和 qPCR 市场分为定量 PCR 和数字 PCR。就产品而言,dPCR 和 qPCR 市场分为试剂和耗材、仪器以及软件和服务。按应用划分,dPCR 和 qPCR 市场分为研究应用、临床应用和法医应用。就最终用户而言,dPCR 和 qPCR 市场分为医院和诊断中心、研究实验室和学术机构、制药和生物技术公司、法医实验室和临床研究组织。 dPCR 和 qPCR 市场根据地理位置分为北美(美国、加拿大和墨西哥)、欧洲(德国、法国、英国、意大利、西班牙和欧洲其他地区)、亚太地区(澳大利亚、中国、日本) 、印度、韩国和亚太地区其他地区)、中东和非洲(南非、沙特阿拉伯、阿联酋以及中东和非洲其他地区)以及南美洲和中美洲(巴西、阿根廷以及南美和非洲其他地区)中美洲)。
细分分析:
dPCR 和 qPCR 市场按处理方式分为定量 PCR 和数字 PCR。数字 PCR 领域在 2022 年占据了更大的市场份额,预计 2022 年至 2030 年市场复合年增长率将更高。数字 PCR (dPCR) 是一种用于检测和定量样品中 DNA 或 RNA 量的技术。 dPCR 是一种高度精确的核酸检测和定量方法,既灵敏又可重复。 dPCR 是精确核酸测量诊断技术的升级形式。 dPCR 具有降低错误率、减少试剂用量、降低实验成本以及不依赖标准和对照等优点。此外,dPCR 具有高度定量性,因为它不依赖于溶液的相对荧光来确定扩增的目标 DNA 的量。与以前的 PCR 程序相比,该技术具有多种优势,包括绝对定量、更高的灵敏度和更全面的动态范围。
许多公司,例如 Thermo Fisher Scientific Inc. 和 Bio-Rad Laboratories, Inc.,提供各种 dPCR 系统以及用于更高灵敏度、精确度和绝对定量的试剂盒和试剂。 2023 年 2 月,Thermo Fisher Scientific Inc. 推出了全新数字 PCR 研究解决方案 Applied Biosystems QuantStudio Absolute Q AutoRun dPCR 套件。此外,人们对尖端液滴数字 PCR 测试的认识不断增强,预计将扩大应用范围。因此,数字 PCR 的优势预计将在预测期内刺激该细分市场的增长。
dPCR 和 qPCR 市场,按处理方式 – 2022 年和 2030 年
根据产品,dPCR 和 qPCR 市场细分为试剂和耗材、仪器以及软件和服务。 2022年,试剂和耗材领域占据了最大的市场份额,预计在2022年至2030年期间将以最快的速度增长。试剂和耗材是 dPCR 和 qPCR 程序的重要组成部分。它包括缓冲液、探针、酶、染料、小瓶、试剂盒、面板等。此外,还有多种试剂盒可用于基因表达分析、SNP 基因分型分析、microRNA 分析等。对早期发现疾病的需求不断增长;消耗品和试剂的广泛使用;医疗保健、研究和其他目的对 PCR 的需求不断扩大,极大地推动了该领域的市场增长。此外,产品的推出和技术接受度的提高是推动该领域市场增长的主要因素。 2023 年 7 月,QIAGEN 推出了面向生物制药行业的 CGT 病毒载体裂解试剂盒,扩大了其 dPCR 试剂盒和服务范围。因此,这些因素推动了试剂和耗材领域的 dPCR 和 qPCR 市场增长。
根据应用,dPCR 和 qPCR 市场分为研究应用、临床应用和法医应用。临床应用领域在 2022 年占据最大的市场份额,预计 2022-2030 年复合年增长率最高。分子生物学技术彻底改变了疾病诊断,现已成为实验室诊断的重要组成部分。 dPCR 和 qPCR 技术现已用于许多疾病的诊断,包括糖尿病、传染病、癌症等。例如,实时PCR技术RIDA GENE试剂盒是为诊断胃肠道感染、医院获得性感染(HAI)、呼吸道感染、性传播感染和其他参数而开发的。由于这些分子方法可以实现早期、灵敏和特异性的诊断,因此临床应用领域预计将在预测期内出现增长。
实时 PCR 技术已用于检测基因突变,这有助于诊断癌症。 dPCR 还能够精确检测游离 DNA (cfDNA) 样本中的肿瘤标志物。此外,地中海贫血、血友病、镰状细胞性贫血、苯丙酮尿症和各种其他疾病等疾病患病率的上升增加了对使用 qPCR 和 dPCR 技术进行筛查的需求。此外,技术进步为诊断和治疗癌症提供了分子标记。 2023 年 4 月,赛默飞世尔科技为其 QuantStudio Dx 系列仪器推出了 37 种带有 CE-IVD 标志的实时 PCR 检测试剂盒,用于检测多种传染病。
根据最终用户,dPCR 和 qPCR 市场分为医院和诊断中心、制药和生物技术公司、研究实验室和学术机构、法医实验室和临床研究组织。医院和诊断中心细分市场在 2022 年占据最大的市场份额,预计 2022 年至 2030 年复合年增长率最高。医院和诊断中心为 dPCR 和 qPCR 市场贡献了重要的市场份额。医院是患者在训练有素的人员指导下寻求先进治疗的主要中心。 dPCR 和 qPCR 具有高灵敏度和特异性等优点,可以早期准确地检测病原体,包括细菌、病毒和真菌。此外,医院为患者提供先进的诊断和治疗选择,以治疗急性和慢性疾病,并且医院和诊断中心对PCR技术的采用率要高得多,因为它们为医疗机构提供了专门的科学设备。对早期有效疾病诊断和治疗的需求不断增长,用于诊断应用的 dPCR 产品推出数量不断增加,dPCR 在疾病诊断中提供的优势(与其他 PCR 技术相比),以及公众对其所提供的好处的认识不断增强这些临床和疾病诊断技术推动了市场增长。
区域分析:
根据地理位置,dPCR 和 qPCR 市场分为北美、欧洲、亚太地区、南美洲和中美洲以及中东和非洲。到 2022 年,北美在全球市场中占据重要份额。该区域市场的增长归因于生物分析仪器制造商和 PCR 公司对创新产品的需求增加、主要市场参与者的存在以及各个学术领域进行的广泛研发和研究机构。医疗保健、政府和私人倡议对先进方法整合的日益关注促进精准医疗,以及政府和私人机构为基因组研究提供的资金不断增加,也为北美 dPCR 和 qPCR 市场带来了非凡的收入。此外,该地区各个研究小组取得的科学进步与该地区在全球市场定位中的增长和主导地位相对应。
行业发展和未来机遇:
全球 dPCR 中的主要参与者采取的各种举措和 qPCR 市场如下:
2023 年 7 月,QIAGEN NV 宣布扩大其数字 PCR (dPCR) 产品范围,用于生物制药行业细胞和基因疗法的开发。该公司与 Niba Labs 合作,为生物制药客户提供定制的数字 PCR 检测设计服务,并推出了新的 CGT 病毒载体裂解试剂盒,该试剂盒实现了从细胞裂解物到多种血清型病毒滴度绝对和精确定量的标准化工作流程。 2021 年,Bio-Rad Laboratories Inc. 推出了 PREvalence ddPCR SARS-CoV-2 废水定量试剂盒,这是一种灵敏、经济高效且准确的仪器,用于检测社区废水中的 SARS-CoV-2。美国疾病控制与预防中心 (CDC) 推荐使用 ddPCR 技术进行废水检测,美国环境保护局 (EPA) 已发布该技术作为量化废水中病毒的可靠方法。竞争格局和主要公司:
雅培 (Abbott Laboratories) 、 Thermo Fisher Scientific Inc.、Takara Bio Inc.、Qiagen NV、乐普医疗科技北京有限公司、F. Hoffmann-la Roche Ltd、Bio-rad Laboratories Inc.、Agilent Technologies Inc.、Standard Biotools Inc. 和 Genome Diagnostics Pvt Ltd 是 dPCR 和 qPCR 市场的知名参与者之一。这些公司专注于推出新的高科技产品、现有产品的进步以及地域扩张,以满足全球不断增长的消费者需求。
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

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to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

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Frequently Asked Questions


What was the estimated dPCR and qPCR market size in 2022?

The dPCR and qPCR market was valued at US$ 8,976.99 million in 2022.

What are the growth estimates for the dPCR and qPCR market till 2030?

The dPCR and qPCR market is expected to be valued at US$ 18,230.74 million in 2030.

What is dPCR and qPCR?

Digital PCR (dPCR) and quantitative PCR (qPCR) are two major types of PCR technologies. dPCR is a new technique utilized for DNA amplification and quantification that uses molecular counting protocol. dPCR is usually used to distinguish the expression of alleles, track viral infection to individual bacterial cells, quantify cancer genes, and detect fetal DNA in circulating blood. On the other hand, qPCR calculates PCR amplification simultaneously as the reaction proceeds.

Which segment is dominating the dPCR and qPCR market?

The global dPCR and qPCR market, based on product, is segmented into reagents & consumables, instruments, and software & services. The reagents & consumables segment held the largest share of the market in 2022 and is anticipated to register the highest CAGR during the forecast period.

What are the driving and restraining factors for the dPCR and qPCR market?

The factors driving the growth of the dPCR and qPCR market include the increasing incidence of genetic and infectious diseases and technological advancements in PCR technologies. However, the high costs of PCR systems hamper the growth of the dPCR and qPCR market.

Who are the major players in the dPCR and qPCR market?

The dPCR and qPCR market majorly consists of the players, including Abbott Laboratories, Thermo Fisher Scientific Inc., Takara Bio Inc., Qiagen NV, Lepu Medical Technology Beijing Co Ltd, F. Hoffmann-la Roche Ltd, Bio-rad Laboratories Inc., Agilent Technologies Inc, Standard Biotools Inc., and Genome Diagnostics Pvt Ltd.

The List of Companies - dPCR and qPCR Market

  1. Abbott Laboratories
  2. Thermo Fisher Scientific Inc.
  3. Takara Bio Inc.
  4. Qiagen NV
  5. Standard Biotools Inc.
  6. Lepu Medical Technology Beijing Co Ltd
  7. F. Hoffmann-la Roche Ltd
  8. Bio-rad Laboratories Inc
  9. Agilent Technologies Inc
  10. Genome Diagnostics Pvt Ltd.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

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  • Validates and strengthens in-house secondary research findings
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Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

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Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

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  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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