人类肝脏模型市场预计将从 2021 年的 2.339 亿美元增至 2028 年的 5.0826 亿美元;预计2021年至2028年复合年增长率为11.7%。
市场的增长主要归因于肝病患病率的增加以及人们对肝病的日益关注。开发动物测试模型的替代方案。然而,人类肝脏模型的高成本以及将肝脏模型纳入现有工作流程的问题阻碍了人类肝脏模型市场的增长。肝脏是一个重要的器官,执行重要的身体功能,例如合成凝血因子、胆汁生成、蛋白质生成和解毒。人体肝脏模型用于研究药物的毒性,并有助于了解药物的作用和肝病的进展。对开发动物试验模型替代品的日益关注是预计未来几年促进全球人类肝脏模型发展的主要因素之一。
战略洞察
由于COVID-19的爆发,亚太地区生物制药行业在2020年的几个月里受到了干扰。由于为控制感染传播而实施的多级限制,COVID-19 大流行以前所未有的方式影响了临床试验。然而,随着治疗 COVID-19 感染的产品需求不断增长,印度和中国的生物制药和制药公司增加了研究活动,这对市场增长产生了积极影响。
人体肝脏模型市场利润丰厚的区域
市场洞察
不断增加肝脏疾病的流行推动了人类肝脏模型市场的增长
肝脏是人体最大的内脏器官,执行 500 多种功能。肝毒性是风险评估中的一个主要问题,因为肝脏暴露于大多数外源化合物及其生物活性代谢物,使其容易受到化学诱发的肝病的影响。丙型肝炎病毒(HCV)、慢性乙型肝炎病毒(HBV)、非酒精性脂肪肝病(NAFLD)和酒精相关性肝病(ALD)是慢性肝病的主要原因。病毒性肝炎仍然是肝功能衰竭导致死亡的主要原因,与此同时,NAFLD 已成为肝脏发病率和相关死亡率增长最快的因素之一。据英国国家统计,肝病已成为该国第五大死因。
此外,这些疾病被认为是第二大死因。是美国所有消化系统疾病的首要死因。据美国肝病研究协会称,2017年,全球肝癌和肝硬化负担有所增加。 NAFLD 在普通人群中的患病率估计约为 25%。近三分之一的美国人患有 NAFLD,而患有 2 型糖尿病或肥胖症的人受到的影响尤为严重; NAFLD 病例数量预计将从 2015 年的 8310 万人增加到 2030 年的 1.009 亿。因此,全球肝脏疾病(包括慢性和急性疾病以及微生物感染)患病率的上升增加了对肝脏模型的需求。
基于类型的见解
根据类型,人类肝脏模型市场进一步细分为肝脏类器官、肝脏芯片、2D 模型、3D 生物打印等。肝脏类器官领域占据最大的市场份额。然而,预计 2021 年至 2028 年肝脏芯片领域的复合年增长率最高。肝脏类器官技术的进步为产前发育、组织保存和病理学提供了模型,这将推动未来几年该领域的市场增长。
人类肝脏模型市场(按类型) 2021年和2028年
基于应用的见解
基于应用,人类肝脏模型市场进一步细分为教育、药物发现等。药物发现领域在人类肝脏模型市场中占有最大份额;然而,教育领域预计在预测期内复合年增长率最高。
基于最终用户的见解
基于最终用户,人类肝脏模型市场分为研究机构、制药和生物技术公司等。制药和生物技术公司领域拥有最大的市场份额。然而,研究机构部门预计在预测期内复合年增长率最高。该细分市场的预计市场增长可归因于行业和大学之间在基因组研究方面的合作增加以及人类肝脏模型生产方面的技术进步。
在人类肝脏模型市场运营的公司正在采用产品创新战略来满足全球不断变化的客户需求,这也使他们能够在全球市场上保持自己的品牌声誉。
人类肝脏模型市场 –按类型
- 肝脏类器官
- 肝脏芯片
- 2D 模型
- 3D 生物打印
- 其他
人类肝脏模型市场 –按应用划分
- 药物发现
- 教育
- 其他
人类肝脏模型市场 –按最终用户划分
- 制药和生物技术公司
- 研究机构
- 其他
人类肝脏模型市场 –按地理位置
- 北美洲
- 美国
- 加拿大
- 墨西哥
< li>欧洲 - 法国
- 德国
- 意大利
- 英国
- 西班牙
- 休息欧洲
- 亚太地区 (APAC)
- 中国
- 印度
- 韩国
- 日本
- 澳大利亚
- 亚太地区其他地区
- 中东和非洲非洲 (MEA)
- 南非
- 沙特阿拉伯
- 阿联酋
- 中东和非洲其他地区
- 南美洲和中美洲 (SCAM)
- 巴西
- 阿根廷
- 其他 SCAM
公司简介
- THERMO FISHER SCIENTIFIC INC.
- Emulate, Inc.
- CN生物创新,
- CYFUSE BIOMEDICAL KK
- MIMETAS BV
- InSphero
- BioIVT
- CELLINK
- Kerafast
- 塞浦路斯
- Kirkstal
- ORGANOVO HOLDINGS INC
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
This text is related
to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
The factors that are driving growth of the market are increasing prevalence of liver diseases, and growing focus on developing alternatives for animal testing models.
Various companies have made organic growth strategies in the human liver models market. Some of the activities undertaken by the company, which have promoted its growth are, launches, enhancements and expansion & relocation activities. Companies such as InSphero, Emulate, Inc amongst others are some of the companies that have been implementing various organic strategies that have helped the growth of the company.
North America dominates the global human liver models market due to factors such as increasing incidences of the liver diseases such as cirrhosis, chronic liver disease (CLD), Nonalcoholic fatty liver disease (NAFLD) and others across the country. Moreover, the growth of market in Canada is expected to grow due to increasing support from the government to address the rising concerns about the liver diseases.
The liver-on-a-chip segment is growing at the highest CAGR owing to increasing demand for cost-effective alternatives to animal models for drug research and development.
Asia Pacific is expected to be the fastest growing region in the Human Liver Models market. The growth of the market in this region is primarily due to growing biopharmaceutical industry, increasing number of clinical trials, and increasing research activities for the development of innovative therapies.
The List of Companies - Human Liver Models Market
- THERMO FISHER SCIENTIFIC INC.
- Emulate, Inc.
- CN Bio Innovations,
- CYFUSE BIOMEDICAL K.K.
- MIMETAS BV
- InSphero
- BioIVT
- CELLINK
- Kerafast
- Cyprio
- Kirkstall
- ORGANOVO HOLDINGS INC
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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