透皮给药系统市场基于(关键地区、市场参与者、规模和份额)- 到 2030 年的预测

  • Report Code : TIPRE00002894
  • Category : Medical Device
  • Status : Published
  • No. of Pages : 233
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【研究报告】透皮给药系统市场预计将从2022年的372.3028亿美元增长到2030年的519.4974亿美元;预计 2022 年至 2030 年复合年增长率为 4.3%。
市场洞察和分析师观点:
透皮给药是一种积极用于在患者皮肤上输送治疗有效量药物的剂型。将含药贴片放置在皮肤上,以将特定剂量的药物通过皮肤输送到血液中。透皮给药系统以受控的速率将药物输送至体循环。推动透皮给药系统市场增长的关键因素包括对无创给药设备的需求不断增长以及慢性病患病率的增加。然而,透皮给药系统的不良反应和召回阻碍了市场增长。
增长驱动因素和限制:
心绞痛、动脉粥样硬化、胸痛和急性心肌梗塞等心血管疾病 (CVD) 是导致市场增长的常见原因。世界上的死亡率。据世界卫生组织称,CVD 是全球每年约 1790 万人死亡的主要原因。市面上有许多治疗心血管疾病的药物,但传统的胶囊和片剂无法有效控制疾病。这强调了对新型药物递送系统的需求,该系统可提供延长的药物生物利用度和靶向药物递送至心血管系统受影响的区域。与口服药物相比,透皮给药系统 (TDDS) 在治疗心血管疾病方面具有多种优势。包含药物颗粒的透皮贴剂应用于皮肤表面。心脏补片为改善细胞植入提供了一个极好的平台。例如,最近开发的血管化心脏补片显示出治疗缺血性心脏损伤的巨大潜力。硝酸甘油透皮贴剂用于预防冠状动脉疾病患者的心绞痛(胸痛)发作。它们的作用是放松血管、减轻心脏压力,从而降低对氧气的需求。
根据阿尔茨海默病协会的报告,阿尔茨海默病在 2019 年导致死亡的主要原因中排名第 6 位,在 2020 年排名第 7 位2021 年在美国。根据美国国立卫生研究院 2023 年的统计数据,65 岁及以上的美国人约有 670 万(即每 9 人中就有 1 人,即人口的 10.8%)患有阿尔茨海默氏痴呆症。患有阿尔茨海默氏痴呆症的人的比例随着年龄的增长而增加。 65-74岁的人中有5%、75-84岁的人有13.1%、85岁及以上的人有33.3%患有阿尔茨海默病。根据 2021 年发布的《全球年轻发病痴呆症患病率》报告,美国 30-64 岁的年轻发病痴呆症患病率估计为每 10 万人中就有 110 人,即总共约 20 万名美国人。 卡巴拉汀贴片治疗与轻度、中度或重度阿尔茨海默病相关的痴呆或与帕金森病相关的轻至中度痴呆。卡巴拉汀和多奈哌齐是胆碱酯酶抑制剂,表现出剂量反应关系;药物剂量越高,疗效越好。一种小的、亲脂性和亲水性的分子,化学性质非常适合透皮递送。
糖尿病是一种危及生命的慢性疾病,没有专门的治疗方法。两种类型的糖尿病都会导致不同身体部位的各种问题,并增加过早死亡的总体风险。根据国际糖尿病联盟(IDF)糖尿病地图集第 10 版,2021 年,全球有 5.37 亿成年人(20-79 岁)患有糖尿病,到 2030 年,这一数字可能会达到 6.43 亿和 7.83 亿。到 2045 年。外源胰岛素通常通过皮下注射来控制糖尿病。然而,最近人们关注的是一种智能贴片,它可以在需要时提供胰岛素,简化胰岛素摄入并激活有针对性的作用。因此,心血管疾病、阿尔茨海默氏病和糖尿病等慢性疾病的发病率不断增加,促进了透皮给药系统市场的增长。
目前上市的透皮给药系统(TDDS)、跨粘膜给药系统(TMDS)和局部给药系统在预期使用期后,贴剂可能会保留初始药物总量的 10-95% 作为残留药物。这给患者及其家人和护理人员带来了潜在的安全问题。例如,由于患者在预期使用期结束时未能去除TDDS而导致的不良事件通常会导致药物的药理作用增加或延长。据报道,一些儿童因意外接触废弃的 TDDS 而死亡。
战略见解
报告细分和范围:
全球透皮给药系统市场根据产品、应用和领域进行分类分销渠道。根据产品,透皮给药系统市场分为透皮贴剂、透皮凝胶、透皮喷雾剂等。根据应用,市场分为心血管疾病、中枢神经系统疾病、疼痛管理、激素应用和其他应用。从分销渠道来看,透皮给药系统市场分为医院药房、零售药房、网上药房等。透皮给药系统市场按地域划分为北美(美国、加拿大和墨西哥)、欧洲(德国、法国、意大利、英国、西班牙和欧洲其他地区)、亚太地区(澳大利亚、中国、日本) 、印度、韩国和亚太地区其他地区)、中东和非洲(南非、沙特阿拉伯、阿联酋以及中东和非洲其他地区)以及南美洲和中美洲(巴西、阿根廷以及南美洲和非洲其他地区)中美洲)。
细分分析:
根据产品,透皮给药系统市场分为透皮贴剂、透皮凝胶、透皮喷雾剂等。透皮贴剂细分市场在 2022 年占据最大市场份额,透皮凝胶细分市场预计在 2022 年至 2030 年期间复合年增长率最高。透皮贴剂是附着在患者皮肤上以通过皮肤输送药物的药物输送系统。透皮贴剂细分市场进一步细分为药包贴剂、储库膜贴剂、基质贴剂和蒸气贴剂。
按产品划分的透皮给药系统市场 – 2022 年和 2030 年
透皮给药系统市场按应用划分,可分为心血管疾病、中枢神经系统疾病、激素应用、疼痛管理和其他应用。疼痛管理细分市场在 2022 年占据最大市场份额。中枢神经系统疾病细分市场预计在 2022 年至 2030 年期间将实现最高的复合年增长率。疼痛管理市场细分为阿片类药物应用和非阿片类药物应用。激素应用细分市场进一步细分为透皮雌激素疗法和睾酮替代疗法。
根据分销渠道,透皮给药系统市场细分为医院药房、零售药房、在线药房等。医院药房细分市场在 2022 年占据最大市场份额。零售药房细分市场预计将在 2022 年至 2030 年期间实现最高的复合年增长率。
区域分析:
基于地理位置,全球透皮药物输送系统市场分为北美、欧洲、亚太地区、南美洲和中美洲以及中东和非洲。 2022年,北美占据最大市场份额。据估计,2022 年至 2030 年,亚太地区的透皮给药系统市场复合年增长率最高。
根据美国心脏协会 (AHA) 的数据,心血管疾病 (CVD) 仍然是美国的首要死因。 CDC 数据显示,CVD 导致约 695,000 例死亡,即 2021 年美国约五分之一的死亡。心血管疾病、糖尿病、慢性疼痛和其他慢性病患病率的上升推动了对有效、便捷治疗的需求选项。医疗贴片提供了一种无创且患者友好的方法来提供药物并管理与这些慢性病相关的症状。 TDDS 的不断进步,例如可穿戴传感器和柔性电子产品,有助于透皮给药系统市场的增长。这些进步可以实现更准确的剂量、增强的患者监测并提高患者的依从性。据Biomaterials Research 2021年发布的报告《透皮给药系统的最新进展》显示,微针在TDDS模式中备受关注,它结合了微针的优点,克服了现有简单涂抹型和贴片型针的局限性。以获得更高的治疗效率和效果。这些TDDS的进步可以为控制心血管和中枢神经系统疾病、糖尿病、神经肌肉疾病以及传染性和局部传染病的患病率提供驱动力。
个性化医疗的增长趋势,其中治疗是针对个体患者量身定制的,促进了提供受控和有针对性的药物输送的医疗贴片的开发。这种定制可以改善患者的治疗效果并提高治疗效果。 2020年,Reddy's Laboratories在美国推出了NitroDur(硝化甘油)透皮输注系统的授权仿制药。随着人们对家庭医疗保健和远程患者监测的日益重视,医疗贴片为在传统医疗保健环境之外输送药物和监测生命体征提供了便捷的解决方案。
美国透皮给药系统市场受到诸如以下因素的影响:慢性病、技术进步以及对个性化药物的日益关注。
行业发展和未来机遇:
全球透皮给药系统市场主要参与者采取的各种举措如下:
10 月2023年,诺华完成仿制药及生物类似药业务山德士100%分拆,成立独立公司。2022年12月,绿叶制药集团在上海举办线下产品发布会,并举办线上活动,宣布若心林(盐酸托鲁地文拉法辛缓释片)在中国上市。若心林是中国首个由地方自主研发的治疗重度抑郁症(MDD)的一类创新化学药物,并受知识产权保护。该药为患者提供了强大的新选择,将MDD的治疗提升到了新的水平。 2021年2月,绿叶制药集团子公司绿叶制药瑞士股份公司与东和制药有限公司(Towa)签订协议。该协议的条款授予 Towa 在日本开发和商业化 Rivastigmine Multi-Day (Rivastigmine MD) 透皮贴剂的独家权利。该贴片表明每周两次透皮应用可治疗阿尔茨海默病。绿叶制药已申请多项国外专利并已获得多项专利来保护该产品。卡巴拉汀MD目前在欧洲处于注册阶段,很快将在欧洲开始III期临床研究。绿叶制药向东和授予卡巴拉汀MD在日本的独家生产和销售权。2021年1月,绿叶制药集团召开新闻发布会,宣布卡巴拉汀透皮贴剂在中国上市。该药物被批准用于治疗轻度至中度阿尔茨海默病,应每日局部使用一次。该公司的德国子公司绿叶制药股份公司利用其独特的透皮贴剂技术生产了该贴剂。除中国外,绿叶制药在美国、欧洲11个国家、泰国等国家销售卡巴拉汀透皮贴剂。2019年12月,久光制药在日本推出治疗帕金森病的透皮贴剂HARUROPI TAPE继2019年11月19日国民健康保险(NHI)药品价格上市后。竞争格局和主要公司:
诺华公司、强生公司、葛兰素史克公司、Viatris Inc、勃林格殷格翰国际有限公司、绿叶制药集团有限公司、 Hisamitsu Pharmaceutical Co Inc、Lavipharm SA、Purdue Pharma LP 和 UCB SA 是透皮给药系统市场的知名参与者。这些公司专注于新技术、现有产品的进步和地域扩张,以满足全球不断增长的消费者需求并扩大其专业产品组合。
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

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to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

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Frequently Asked Questions


What was the estimated transdermal drug delivery systems market size in 2022?

The transdermal drug delivery systems market was valued at US$ 37,230.28 million in 2022.

What factors drive the transdermal drug delivery systems market?

Factors such as growing demand for noninvasive drug delivery devices and the increasing prevalence of chronic diseases propel market growth.

Who are the major players in the transdermal drug delivery systems market?

The transdermal drug delivery systems market majorly consists of the players, including Novartis AG, Johnson & Johnson, GSK Plc, Viatris Inc, Boehringer Ingelheim International GmbH, Luye Pharma Group Ltd, Hisamitsu Pharmaceutical Co Inc, Lavipharm SA, Purdue Pharma LP, and UCB SA.

What is transdermal drug delivery system?

Transdermal drug delivery systems are dosage forms actively used to deliver a therapeutically effective amount of drug across a patient’s skin. It is a type of medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. Transdermal drug delivery systems deliver the drug at a controlled rate to the systemic circulation.

Which product segment dominates the transdermal drug delivery systems market?

Based on product, the transdermal drug delivery system market is segmented into transdermal patches, transdermal gels, transdermal sprays, and others. The transdermal patch segment is further segmented into drug-in-adhesive patches, reservoir membrane patches, matrix patches, and vapor patches. The transdermal patches segment held the largest share of the market in 2022, while transdermal gels is anticipated to register the highest CAGR during 2022–2030.

What are the growth estimates for the transdermal drug delivery systems market till 2030?

The transdermal drug delivery systems market is expected to be valued at US$ 51,949.74 million in 2030.

Which application segment dominates the transdermal drug delivery systems market?

The transdermal drug delivery system market, by application, has been segmented into cardiovascular diseases, central nervous system disorders, hormonal applications, pain management, and other applications. The market for the pain management segment is sub-segmented into opioid application and non-opioid application. The market for hormonal application segment is further segmented into transdermal estrogen therapy and testosterone replacement therapy. The pain management segment held the largest share of the market in 2022. Central nervous system disorders segment is expected to register the highest CAGR in the market during 2022–2030.

Which distribution channel segment dominates the transdermal drug delivery systems market?

Based on the distribution channel, the transdermal drug delivery system market is segmented into hospital pharmacies, retail pharmacies, online pharmacies, and others. The hospital pharmacies segment held the largest share of the market in 2022. However, the retail pharmacies segment is expected to register the highest CAGR in the market during 2022–2030.

The List of Companies - Transdermal Drug Delivery System Market

  1. Novartis AG  
  2. Johnson & Johnson
  3. GSK Plc
  4. Viatris Inc  
  5. Boehringer Ingelheim International GmbH
  6. Hisamitsu Pharmaceutical Co Inc
  7. Luye Pharma Group Ltd
  8. Lavipharm SA
  9. Purdue Pharma LP
  10. UCB SA

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

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The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

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Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

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Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

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  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

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We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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