瞬时蛋白表达市场基于(关键地区、市场参与者、规模和份额)- 到 2031 年的预测

  • Report Code : TIPRE00017081
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 190
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2019年瞬时蛋白表达市场价值为6.600亿美元,预计到2027年将达到9.831亿美元;预计从 2020 年到 2027 年,复合年增长率将达到 5.3%。

瞬时蛋白表达是一种通常用于获得几毫克蛋白质的过程。一百毫克蛋白质。一旦编码表达的DNA被引入动物或植物细胞中,它就是在短时间内表达的过程。它是使用电穿孔技术进行的,该技术允许筛选大量突变体,以确定它们与受体和效应器有效联网的能力。   

瞬时蛋白表达市场的范围包括产品类型、应用、最终用户和地理位置。根据北美、欧洲、亚太地区、中东和美国等地区分析了瞬时蛋白表达市场。非洲、南美和非洲中美洲。该报告提供了对瞬时蛋白表达市场的见解和深入分析,重点关注各种参数,例如市场趋势、技术进步、市场动态以及全球领先市场参与者的竞争格局分析

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瞬时蛋白表达市场利润丰厚的区域


市场洞察

瞬时蛋白表达程序已被广泛应用过去三十年来一直用于动物和植物细胞。然而,近年来,蛋白质组学的重大发展导致了重组蛋白的发展。动物和植物中瞬时蛋白表达的有效结果增加了人类应用的研究和产品开发。

包括生物制药和合同研发组织在内的各种公司已将其渠道化他们致力于开发基于瞬时蛋白表达的产品。采用瞬时蛋白表达技术使公司能够获得各种基因来开发重组蛋白,而不会延迟细胞系的生成。因此,随着所需基因表达的细胞系开发的快速过程,公司广泛被具有药物样特性的统一蛋白质所吸引,这使得疫苗和病毒载体的生产成为可能。此外,瞬时蛋白表达工艺广泛应用于单克隆抗体、修饰人类蛋白、生长因子和细胞因子、激素和血液制品的生产。

COVID-19大流行导致了在疫苗开发中使用瞬时蛋白表达。各种研究人员已经开始利用瞬时蛋白表达来广泛研究这种新型冠状病毒。例如,2020 年 3 月至 4 月,Absolute Antibody(英国)增加了数克数量的多种抗 SARS-CoV-2 刺突蛋白的产量,以开发中和抗体。同样,瞬时蛋白表达被广泛用于体外诊断试剂盒开发中产生阳性对照蛋白。

精准医疗的采用不断增加

技术进步增加了分子生物学技术的采用,用于开发各种治疗或治疗方式。不同的治疗方式利用基因组、转录组信息来促进生物标志物的发现,以监测疾病并预测其风险。由于人们对基因变异的认识,个性化或精准药物的使用急剧增加。例如,mRNA介导的疗法用于治疗多种疾病,因为该疗法的特点是免疫原性降低、翻译功效优异、稳定性增强、药物安全性和瞬时蛋白表达,因为仅修饰mRNA而不掺入宿主基因组。

同样,制药和生物技术行业也开发了各种治疗癌症和神经退行性疾病的技术。瞬时基因表达技术导致了神经创伤和神经退行性疾病相关研究的重大发展,并导致针对这些疾病的精准医学的引入。表观遗传学、遗传学和蛋白质组学的技术进步正在支持治疗由单细胞和多细胞疾病引起的各种遗传性和罕见遗传性疾病的疗法的开发。

2015年在美国发起的精准医学计划加强了基因工程、基因组学和蛋白质组学的应用,从而增加了瞬时蛋白表达技术的使用。因此,持续的研发活动以及政府支持精准医疗的举措的增加促进了瞬时蛋白表达技术的采用。

产品类型洞察

根据产品类型,全球瞬时蛋白表达市场分为仪器、试剂、载体和感受态细胞。 2019年,仪器仪表领域占据最大的市场份额。该细分市场预计将在 2027 年占据市场主导地位,因为它们减少了人力投入,从而实现了持续的细胞维护和蛋白质生产。此外,预计同一细分市场在预测期内将以最快的速度增长。

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应用洞察

根据应用,全球瞬时蛋白表达市场分为基因组研究、基因治疗、生物生产、癌症研究和药物开发。 2019年,基因组研究领域在瞬时蛋白表达市场中占据最大的市场份额。由于提高了 DNA 测序性能,预计到 2027 年该细分市场将主导市场。此外,瞬时蛋白表达有助于研究一个人的所有基因(基因组),包括它们彼此之间以及环境之间的相互作用。

最终用户洞察

就最终用户而言,全球瞬时蛋白表达市场分为制药和生物技术公司、学术和研究机构以及临床研究组织。 2019年,制药和生物技术公司细分市场占据最大的市场份额。由于制药和生物技术公司正在增加研究和研发活动的支出,预计该细分市场在预测期内也将主导市场。此外,瞬时蛋白表达有助于近期现有技术的改进,正在向植物疫苗、抗体和生物制药的工业化生产迈进。

全球瞬时蛋白表达市场,按最终用户划分 – 2019年& 2027


战略洞察

产品发布和合并与重组收购被认为是全球瞬时蛋白表达行业最常用的策略。以下列出了近期的一些关键产品开发:

2020年1月:Ambrx和中国生物制药宣布合作开发两种下一代生物制剂,以开发由Ambrx独特的非天然氨基酸掺入技术平台支持的两种产品。此次合作将 Ambrx 经过临床验证的 ReCODE 和 EuCODE 平台与中国生物制药强大的资源和致力于将下一代生物药物推向市场的承诺相结合。
2018 年:安捷伦宣布与 Young In Scientific Co 签署收购相关业务的最终协议. Ltd. 是韩国领先的分析和科学仪器经销商,也是安捷伦仪器和服务的长期经销商。
2017 年:Thermo Fisher Scientific Inc. 推出了全新 PureLink Fast Low-内毒素质粒纯化 Midi 和 Maxi 试剂盒,可显着缩短质粒纯化时间,加速蛋白表达。
预计冠状病毒大流行将对瞬时蛋白表达市场产生重大影响。全球大多数制药公司都在从事冠状病毒疫苗的开发。然而,这种重点转移预计将对市场的其他部分产生负面影响。此外,由于全球运营停止而造成的供应链中断预计将对市场产生不利影响。

瞬时蛋白表达 –市场细分

按产品类型

  • 仪器
    • 自动化瞬时蛋白表达系统
    • 手动瞬时蛋白表达系统
  • 试剂
  • 表达载体
  • 感受态细胞

按应用分类

  • 基因组研究
  • 基因治疗
  • 生物生产
  • 癌症研究
  • 药物开发

最终用户

  • 制药和生物技术公司
  • 学术和研究机构
  • 临床研究组织

按地理位置

  • 北美洲
    • 美国
    • 加拿大
    • 墨西哥
  • 欧洲
    • 法国
    • >
    • 德国
    • 英国
    • 意大利
    • 西班牙
    • 欧洲其他地区
  • 亚太地区 (APAC)
    • 中国
    • 日本
    • 印度
    • 澳大利亚
    • 韩国< /li>
    • 亚太地区其他地区
  • 中东和中东地区非洲 (MEA)
    • 沙特阿拉伯
    • 南非
    • 阿联酋
    • 中东其他地区和地区非洲
  • 南美洲(SCAM)
    • 巴西
    • 阿根廷
    • 南部和非洲其他地区中美洲

公司简介

  • Thermo FISHER SCIENTIFIC INC.
  • >
  • MERCK KGaA
  • QIAGEN
  • GenScript
  • Promega Corporation
  • Takara Bio Inc.
  • MERIDIAN BIOSCIENCE, INC.
  • 新英格兰生物实验室
  • 安捷伦科技公司
  • Mirus Bio LLC
  • 中国生物科技有限公司
  • >
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is Transient protein expression?

Transient protein expression is a procedure that is usually used to convert a few milligrams of protein to a hundred milligrams of protein. It is a procedure expressed in a short time once the DNA encoding expression has been introduced to animal or plant cells. It is performed using an electroporation technique that allows large numbers of mutants to be screened for their abilities to network productively with receptors and effectors.

What are the driving factors for the Transient protein expression market across the globe?

The factors that are driving growth of the market are increasing applications of protein expression and growing adoption of precision medicines are expected to boost the growth of the global transient protein expression market.

Who are the major players in the Transient protein expression market?

The transient protein expression market majorly consists of the players such Thermo Fisher Scientific, Promega Corporation, Merck Kgaa, Takara Bio Inc, Qiagen, Genscript, Meridian Bioscience, Inc, Agilent Technologies, Inc., New England Biolabs, And Mirus Bio Llc., Sino Biological Inc are among others.

The List of Companies - Transient Protein Expression Market

  1. THERMO FISHER SCIENTIFIC INC.
  2. MERCK KGaA
  3. QIAGEN
  4. GenScript
  5. Promega Corporation
  6. Takara Bio Inc.
  7. MERIDIAN BIOSCIENCE, INC.
  8. New England Biolabs
  9. Agilent Technologies, Inc.
  10. Mirus Bio LLC
  11. Sino Biological Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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