类病毒颗粒市场基于(关键地区、市场参与者、规模和份额)- 到 2031 年的预测

  • Report Code : TIPRE00025763
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 163
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病毒样颗粒 (VLP) 市场预计将从 2021 年的 46.0184 亿美元增至 2028 年的 78.5882 亿美元;预计2021年至2028年复合年增长率为7.9%。

针对人类和动物病毒的类病毒颗粒疫苗的商业化,蓬勃发展开发基于病毒样颗粒的病毒疫苗的研发活动,以及病毒样颗粒作为过敏性疾病的可靠免疫治疗平台的出现,是整体市场增长的关键驱动因素。然而,与 eVLP 的设计、纯化和存储相关的技术挑战阻碍了整体市场的增长。此外,与病毒样颗粒疫苗制造相关的复杂性,加上工艺的成本和时间要求过高(例如基于病毒样颗粒的疫苗的下游加工),进一步限制了全球市场的增长。此外,针对局部和新出现的病毒性疾病以及癌症的类病毒颗粒疗法仍在开发中,这为整体市场增长带来了利润丰厚的机会。

战略见解


北美可能会在 2021 年至 2028 年继续在病毒类颗粒市场占据主导地位。美国占据北美市场最大份额,预计在预测期内将继续这一趋势。这主要归因于人们普遍观察到的对病毒感染的易感性,例如由不同变种引起的病毒性流感。此外,生产减毒活疫苗所需的持续研发活动迫使生物制药公司选择病毒样颗粒,这进一步支持了市场增长。

病毒样颗粒 (VLP) 市场利润丰厚的区域


市场洞察

基于疫苗的商业化病毒样颗粒推动整体市场增长

根据 Frontiers Media SA 发布的一份报告,第一种病毒-类病毒颗粒疫苗旨在对抗致命的乙型肝炎病毒,与传统疫苗相比,类病毒颗粒疫苗已产生了有希望的安全结果。第一个商业化的病毒样颗粒疫苗是针对乙肝病毒的。另外,商业化的抗HBV疫苗,即葛兰素史克公司生产的“Engerix”和默沙东公司生产的“Recombivax HB”。 Co.于1980年批准上市,它们都是病毒样颗粒。下一个市售的基于病毒样颗粒的疫苗是“Gardasil”,它于 2006 年被批准用于预防人乳头瘤病毒 (HPV) 感染。此外,病毒样颗粒也用于兽医学。第一种基于病毒样颗粒的市售兽用疫苗被证明对猪圆环病毒2型(PCV2)有效。

病毒样颗粒在研发中的作用针对过敏性疾病的免疫治疗产品进一步刺激了整体市场的增长。病毒样颗粒用于治疗过敏性鼻炎、哮喘和尘螨反应。上述因素推动了整个病毒样颗粒市场呈指数级增长。病毒样颗粒疫苗显示出快速的免疫反应,并伴有轻微的皮肤反应副作用。

基于产品类型的洞察

根据产品类型,病毒样颗粒市场分为肝炎、癌症/HPV和戈谢病疾病。 2021 年至 2028 年,肝炎细分市场将占据很大的市场份额。 Frontiers SA 的报告指出,丙型肝炎病毒 (HCV) 感染了全球 2% 的人口,它是肝病和肝移植的主要原因。这种医疗威胁可以通过引入新的抗病毒疗法来部分解决。例如,针对高危静脉吸毒者的疫苗功效为 50-80%,可显着降低人群中丙型肝炎病毒的发病率。因此,病毒样颗粒代表了一种安全且高免疫原性的疫苗递送平台,可诱导适应性免疫反应。几种基于病毒的颗粒疫苗目前正处于临床试验阶段;然而,获得许可的 HBV 和 HPV VLP 疫苗早已使用。因此,基于病毒样颗粒的疫苗已证明其有效性与良好的免疫学特性有关,使其成为有前途的 HCV 疫苗之一。

病毒样颗粒(VLP)市场(按产品类型) 2020 年和 2028 年


基于来源的见解

根据来源,病毒样颗粒 (VLP) 市场分为酵母、昆虫细胞、植物等。酵母细分市场占有相当大的市场份额,预计在预测期内将继续保持类似的趋势。病毒样颗粒由异源表达系统产生,包括酵母或杆状病毒以及植物和细菌。使用酵母表达系统生产的病毒样颗粒疫苗的安全性有助于酵母病毒样颗粒市场的增长。

基于应用见解

按照应用,病毒样颗粒市场分为疫苗和治疗药物。到 2021 年,疫苗细分市场将占据相当大的市场份额,并且在预测期内也可能继续保持其在市场上的主导地位。疫苗接种被认为是人类和动物控制病原体和预防疾病的最有效方法之一。基于病毒的颗粒疫苗由于其固有的免疫原性和安全性而成为最有吸引力的方法之一。例如,病毒样颗粒是具有颗粒结构的非感染性多聚体抗原,适合诱导安全且有效的体液和细胞免疫应答。除此之外,病毒样颗粒疫苗已在兽医领域证明了其有效性。病毒样颗粒仅由一种或多种结构蛋白组成,不存在天然病毒的基因组,并且不能在细胞中自我复制。然而,可以生产含有单价或多价抗原的病毒样颗粒,以满足血清学监测的要求,病毒样颗粒疫苗在兽医领域的应用被证明是有前景的。一个这样的例子是在区分感染者与已接种动物(DIVA)疫苗接种策略下利用病毒样颗粒疫苗来对抗动物疾病。

使用病毒样颗粒疫苗运营的公司( VLP)市场采用产品创新策略来满足世界各地不断变化的客户需求,这也使他们能够在全球市场上保持其品牌声誉。

病毒样颗粒 (VLP) 市场 –按产品类型

  • 肝炎
  • 癌症/HPV
  • 戈谢病

病毒样颗粒 (VLP) )市场——按来源

  • 酵母
  • 昆虫细胞
  • 植物
  • 其他

病毒-类颗粒 (VLP) 市场 –按应用划分

  • 疫苗
  • 治疗

病毒样颗粒 (VLP) 市场 –按地理位置

  • 北美洲
    • 美国
    • 加拿大
    • 墨西哥
  • < li>欧洲
    • 法国
    • 德国
    • 意大利
    • 英国
    • 西班牙
    • 休息欧洲
  • 亚太地区 (APAC)
    • 中国
    • 印度
    • 韩国
    • 日本
    • 澳大利亚
    • 亚太地区其他地区
  • 中东和非洲 (MEA)
    • 南非
    • 沙特阿拉伯
    • 阿联酋
    • MEA其他地区
  • 南美洲和中美洲(SCAM )
    • 巴西
    • 阿根廷
    • 其余骗局

 

公司简介

  • 默克公司有限公司
  • 葛兰素史克公司
  • 辉瑞公司
  • Dynavax Technologies
  • 赛诺菲
  • 万泰BioPharm
  • 印度血清研究所列兵。有限公司
  • BHARAT BIOTECH
  • LG Chem
  • VBI Vaccines Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is the regional market scenario of virus-like particles (VLP's) market?

Global virus-like particles (VLP's) market is segmented by region into North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America. In North America, the U.S. is the largest market for virus-like particles (VLP’s). The US is estimated to hold the largest share in the virus-like particles (VLP’s) market during the forecast period. Presence of top players and favorable regulations related to product approvals coupled with commercializing new products are the contributing factors for the regional growth. Additionally, increasing number of R&D activities is the key factor responsible for the Asia-Pacific regional growth for VLP’s accounting fastest growth of the region during the coming years.

Who are the key players in the virus-like particles (VLP's) market?

Answer: - Merck & Co., Inc., GlaxoSmithKline plc., Pfizer Inc., Dynavax Technologies, Sanofi, Wantai BioPharm, Serum Institute of India Pvt. Ltd., BHARAT BIOTECH, LG Chem, and VBI Vaccines Inc. are among the leading companies operating in the global Virus-Like Particles (VLP's) market

Which application segment held the largest revenue (US$ Mn) in the virus-like particles (VLP's) market?

The vaccine segment dominated the global virus-like particles (VLP's) market and accounted for the largest revenue of 4,558.08 Mn in 2021.

Which segment led the virus-like particles (VLP's) market?

Based on product-type, hepatitis segment took the forefront lead in the worldwide market by accounting largest share in 2020 and is expected to continue to do so till the forecast period.

What is meant by virus-like particles (VLP's)?

American Society for Microbiology defines virus-like particles (VLP's) as non-infectious multiprotein structure that are engineered to self-assemble from viral structure proteins. VLP technology proves to be a very powerful tool involved in development of vaccines. Several VLP based vaccines exist in the global market involving hepatitis B virus and human papillomavirus.

What are the driving factors for the virus-like particles (VLP's) market across the globe?

Commercial VLP based vaccines against human and animal viruses, intensive research and development activities for the development of VLPs based vaccines effective against viral infections, and VLPs acting as the best immunotherapy platform for allergic diseases are the key driving factors responsible for the overall market growth.

The List of Companies - Virus-like Particles (VLP's) Market

  1. Merck & Co., Inc.
  2. GlaxoSmithKline plc.
  3. Pfizer Inc.
  4. Dynavax Technologies
  5. Sanofi
  6. Wantai BioPharm
  7. Serum Institute of India Pvt. Ltd.
  8. BHARAT BIOTECH
  9. LG Chem
  10. VBI Vaccines Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

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The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

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Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

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  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

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We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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