Mercado del síndrome de Netherton: mapeo competitivo y perspectivas estratégicas para 2031

  • Report Code : TIPRE00013771
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 76
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El mercado del síndrome de Netherton se valoró en 19,57 millones de dólares en 2019 y se prevé que alcance los 74,31 millones de dólares en 2027; se espera que crezca a una tasa compuesta anual del 20,3 % entre 2020 y 2027.

El síndrome de Netherton es un trastorno poco común caracterizado por tricorrexis invaginata, diátesis atópica y eritrodermia ictiosiforme. La tricorrexis invaginata indica cabello corto y quebradizo, la diátesis atópica representa susceptibilidad a problemas de alergia mientras que la eritrodermia ictiosiforme abarca la piel enrojecida, inflamada y escamosa. El síndrome de Netherton es hereditario ya que es un rasgo autosómico recesivo. La enfermedad se debe principalmente a mutaciones asociadas con el gen SPINK5. En algunos casos, aunque no hay antecedentes familiares de la enfermedad, el síndrome se revela incluso cuando dos padres sanos que portan el gen recesivo mutado tienen un hijo que recibe ambas copias del gen recesivo. El mercado del síndrome de Netherton está experimentando un enorme crecimiento gracias a la creciente conciencia sobre el síndrome de Netherton y al creciente número de presentaciones de productos. Además, el creciente número de ensayos clínicos y la sólida cartera de productos actúan como oportunidades importantes para el crecimiento futuro de los actores del mercado. Sin embargo, el riesgo de reacciones adversas asociadas con los medicamentos para el tratamiento del síndrome de Netherton frena el crecimiento del mercado.

regiones lucrativas en el mercado mundial del síndrome de Netherton


Perspectivas del mercado

Número cada vez mayor de campañas de concientización sobre el síndrome de Netherton para impulsar el crecimiento

El síndrome de Netherton es un raro trastorno autosómico recesivo relacionado con la piel que afecta el cabello, la piel y el sistema inmunológico. La enfermedad suele afectar a los recién nacidos, en los que la piel suele estar enrojecida y escamosa, además de perder líquidos en algunos casos. Los pacientes que padecen esta afección generalmente desconocen las opciones de tratamiento disponibles y no tienen fácil acceso ni amplia información sobre los cuidados que se deben tomar. Las campañas de concientización tienen un impacto en términos de permitir un diagnóstico oportuno y preciso. Por ello, diversas organizaciones médicas y sociales están trabajando para concienciar y ayudar a los pacientes que padecen el síndrome de Netherton en todo el mundo.

Foundation for Ichthyosis& Tipos de piel relacionados (FIRST), en colaboración con el Consejo Nacional de Salud (NHC), desarrollaron una organización que tiene como objetivo mejorar vidas y buscar curas para los pacientes afectados por ictiosis y tipos de piel relacionados. La organización proporciona información precisa y oportuna sobre el síndrome de Netherton y la ictiosis que ayuda a los pacientes a satisfacer las necesidades sociales, médicas y educativas de la comunidad enferma. Además, el Grupo de Apoyo a la Ictiosis (ISG) tiene como objetivo proteger y preservar la salud y aliviar a los pacientes afectados por ictiosis y otras afecciones asociadas. El ISG proporciona paquetes de información, distribuye boletines y hojas informativas, organiza campamentos residenciales para niños y otros.
Por lo tanto, se espera que las campañas de concientización y los programas para informar a los pacientes y otras personas sobre el síndrome de Netherton aumenten el crecimiento de la mercado en los próximos años.

Información basada en la terapia

Basado en la terapia, el mercado global del síndrome de Netherton se segmenta en agentes queratolíticos, orales y esteroides y retinoides tópicos, inhibidores tópicos de la calcineurina, terapias biológicas y radioterapias. En 2019, el segmento de agentes queratolíticos tuvo la mayor cuota de mercado. El crecimiento de este mercado segmentario se atribuye a los crecientes lanzamientos de productos y a la sólida cartera de productos existente. Además, las actividades estratégicas de los proveedores de servicios, como colaboraciones, fusiones y adquisiciones, y expansiones para acelerar el cronograma de medicamentos, están acelerando aún más el crecimiento del mercado. Sin embargo, se proyecta que el segmento de terapia biológica registre la CAGR más alta en el mercado global del síndrome de Netherton durante 2020-2027.

Mercado del síndrome de Netherton, por terapia: 2019 y 2027


Perspectivas estratégicas

Los lanzamientos de productos y las colaboraciones en investigación son las estrategias comúnmente adoptadas por las empresas para expandir su presencia en todo el mundo y satisfacer la creciente demanda de los consumidores. Los actores del mercado del síndrome de Netherton adoptaron la estrategia de innovación de productos para satisfacer la cambiante demanda de los clientes en todo el mundo, lo que también les permite mantener su marca a nivel mundial.

Síndrome de Netherton Mercado: por terapia

  • Agentes queratolíticos
  • Esteroides y retinoides orales y tópicos
  • Inhibidores tópicos de la calcineurina
  • Radioterapias
  • Terapias Biológicas

Mercado del Síndrome de Netherton – ndash; por Geografía

  • América del Norte
    • Estados Unidos
  • Europa
    • Francia
    • Alemania
    • Italia
    • Reino Unido
    • España
  • Asia Pacífico (APAC)
      < li>Japón

Perfiles de empresas

  • Lifemax Laboratories, Inc.
  • Azitra, Inc.
  • Sixera Pharma Ab
  • Dermelix Biotherapeutics
  • Matrisys Bioscience
  • Quoin Pharmaceuticals Ltd.
  • Krystal Biotech, Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is Netherton syndrome?

Netherton syndrome is a rare genetic disorder that presents the three following characteristics: Ichthyosiform erythroderma, a red, inflamed, scaly skin. Trichorrhexis invaginata – short, brittle, lustreless hair, Atopic diathesis – predisposition to allergy problems. Netherton syndrome is inherited as an autosomal recessive trait disease. The NS condition is caused by mutations in the SPINK5 gene that is found on the chromosome. In some cases, there is no family history of the disease. NS is revealed when two unaffected parents (recessive) and both are carriers of the mutated recessive gene have a child who receives both copies of the recessive gene.

What are the driving factors for the Netherton syndrome market across the globe?

The factors that are driving growth of the market are increasing number of Netherton syndrome awareness campaigns and growing number of product launches with robust pipeline. Moreover, strategic activities by the manufacturers are offering lucrative opportunities for the growth of the market.

Who are the major players in the Netherton syndrome market?

The Netherton syndrome market majorly consists of the players such as Lifemax Laboratories, Inc., Azitra, Inc., Sixera Pharma Ab, Dermelix Biotherapeutics, Matrisys Bioscience, Quoin Pharmaceuticals Ltd., and Krystal Biotech, Inc. among others.

The List of Companies - Netherton Syndrome Market

  1. Lifemax Laboratories, Inc.
  2. Azitra, Inc.
  3. Sixera Pharma Ab
  4. Dermelix Biotherapeutics
  5. Matrisys Bioscience
  6. Quoin Pharmaceuticals Ltd.
  7. Krystal Biotech, Inc

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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