Netherton Syndrome Market to Grow at a CAGR of 20.3% to reach US$ 74.31 Million from 2020 to 2027

Netherton Syndrome Market Forecast to 2027 - COVID-19 Impact and Global Analysis by Therapy (Keratolytic Agents, Oral and Topical Steroids and Retinoids, Topical Calcineurin Inhibitors, Radiation Therapy, and Biological Therapy), and Geography

  • Report Code : TIPRE00013771
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 76
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The Netherton syndrome market was valued at US$ 19.57 million in 2019 and is projected to reach US$ 74.31 million 2027; it is expected to grow at a CAGR of 20.3%from 2020 to 2027.

Netherton syndrome is a rare disorder characterized by trichorrhexis invaginata, atopic diathesis, and ichthyosiform erythroderma. The trichorrhexis invaginata indicates short and brittle hair, atopic diathesis represents susceptibility to allergy problems while ichthyosiform erythroderma encompasses red, inflamed, scaly skin. Netherton syndrome is hereditary as it is an autosomal recessive trait. The disease is majorly caused due to mutations associated with SPINK5 gene. In some cases, although there is no family history of the disease, the syndrome is revealed even when two healthy parents that carry the mutated recessive gene have a child, which receives both copies of the recessive gene. The Netherton syndrome market is witnessing huge growth on the back of the increasing awareness regarding Netherton syndrome and growing number of product introductions. Moreover, rising number of clinical trials and robust pipeline of products act as significant opportunities for the future growth of the market players. However, the risk of adverse reactions associated with the Netherton syndrome treatment drugs restrains the growth of the market.

Lucrative Regions in Global Netherton Syndrome Market

Lucrative Regions in Global Netherton Syndrome Market
  • Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.

Market Insights

Increasing Number of Awareness Campaigns for Netherton Syndrome to Drive the Growth

Netherton syndrome is an autosomal recessive rare skin-related disorder that affects the hair, skin and immune system. The disease usually affects newborns in which, the skin is usually red and scaly as well as leak fluids in some cases. The patients suffering with this condition are usually unaware of the treatment options available as well as do not have easy access and ample information regarding the care to be taken. Awareness campaigns are impactful in terms of enabling timely and accurate diagnosis. Thus, various medical and social organizations are working towards spreading awareness and helping the patients suffering with Netherton syndrome around the world.

Foundation for Ichthyosis& Related Skin Types (FIRST) in collaboration with National Health Council (NHC) developed an organization that aims to improve lives and seek cures for the patients affected by ichthyosis and related skin types. The organization provides accurate and timely information regarding Netherton syndrome and ichthyosis that helps the patients to meet social, medical and educational needs of the disease community. Furthermore, the Ichthyosis Support Group (ISG) aims to protect and preserve the health and relieves patients affected by ichthyosis and other associated condition. The ISG provides information pack, distributes bulletins and newsletters organize children’s residential camps and others.
Thus, the awareness campaigns and programs for informing the patients and other people regarding Netherton’s syndrome are expected to augment the growth of the market over the coming years.

Therapy-Based Insights

Based on therapy, the global Netherton syndrome market is segmented into keratolytic agents, oral and topical steroids and retinoids, topical calcineurin inhibitors, biological therapies, and radiation therapies. In 2019, the keratolytic agents segment held the largest share of the market. Growth of this segmental market is attributed to the increasing product launches and robust existing product pipeline. In addition, strategic activities by service providers such as collaborations, mergers and acquisitions, and expansions to expedite drug timeline are further accelerating the growth of the market. However, the biological therapy segment is projected to register the highest CAGR in the global Netherton syndrome market during 2020–2027.

Netherton Syndrome Market, by Therapy – 2019 and 2027



Netherton Syndrome Market, by Therapy – 2019 and 2027
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Netherton Syndrome Market: Strategic Insights

netherton-syndrome-market
Market Size Value inUS$ 19.57 Million in 2019
Market Size Value byUS$ 74.31 million by 2027
Growth rateCAGR of 20.3% from 2020-2027
Forecast Period2020-2027
Base Year2020
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Product launches and research collaborations are the commonly adopted strategies by companies to expand their footprint worldwide and meet the growing consumer demand. The Netherton syndrome market players adopted the strategy of product innovations to cater to changing customer demand across the world, which also permits them to maintain their brand name globally.

Netherton Syndrome Market – by Therapy

  • Keratolytic Agents
  • Oral and Topical Steroids and Retinoid
  • Topical Calcineurin Inhibitors
  • Radiation Therapies
  • Biological Therapies

Netherton Syndrome Market – by Geography

  • North America
    • US
  • Europe
    • France
    • Germany
    • Italy
    • UK
    • Spain
  • Asia Pacific(APAC)
    • Japan

Company Profiles

  • Lifemax Laboratories, Inc.
  • Azitra, Inc.
  • Sixera Pharma Ab
  • Dermelix Biotherapeutics
  • Matrisys Bioscience
  • Quoin Pharmaceuticals Ltd.
  • Krystal Biotech, Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Therapy , and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

France, Germany, Italy, Japan, Spain, United Kingdom, United States

Frequently Asked Questions


What is Netherton syndrome?

Netherton syndrome is a rare genetic disorder that presents the three following characteristics: Ichthyosiform erythroderma, a red, inflamed, scaly skin. Trichorrhexis invaginata – short, brittle, lustreless hair, Atopic diathesis – predisposition to allergy problems. Netherton syndrome is inherited as an autosomal recessive trait disease. The NS condition is caused by mutations in the SPINK5 gene that is found on the chromosome. In some cases, there is no family history of the disease. NS is revealed when two unaffected parents (recessive) and both are carriers of the mutated recessive gene have a child who receives both copies of the recessive gene.

What are the driving factors for the Netherton syndrome market across the globe?

The factors that are driving growth of the market are increasing number of Netherton syndrome awareness campaigns and growing number of product launches with robust pipeline. Moreover, strategic activities by the manufacturers are offering lucrative opportunities for the growth of the market.

Who are the major players in the Netherton syndrome market?

The Netherton syndrome market majorly consists of the players such as Lifemax Laboratories, Inc., Azitra, Inc., Sixera Pharma Ab, Dermelix Biotherapeutics, Matrisys Bioscience, Quoin Pharmaceuticals Ltd., and Krystal Biotech, Inc. among others.

The List of Companies - Netherton Syndrome Market

  1. Lifemax Laboratories, Inc.
  2. Azitra, Inc.
  3. Sixera Pharma Ab
  4. Dermelix Biotherapeutics
  5. Matrisys Bioscience
  6. Quoin Pharmaceuticals Ltd.
  7. Krystal Biotech, Inc

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Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

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  • 3.1 Macro-Economic Factor Analysis:

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  1. Data Triangulation and Final Review:

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