Marché du syndrome de Netherton – Analyse des tendances et de la croissance | Année de prévision 2031

  • Report Code : TIPRE00013771
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 76
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Le marché du syndrome de Netherton était évalué à 19,57 millions de dollars américains en 2019 et devrait atteindre 74,31 millions de dollars américains en 2027 ; il devrait croître à un TCAC de 20,3 % de 2020 à 2027.



Le syndrome de Netherton est une maladie rare caractérisée par le trichorrhexis invaginata, la diathèse atopique et l'érythrodermie ichtyosiforme. Le trichorrhexis invaginata indique des cheveux courts et cassants, la diathèse atopique représente une susceptibilité aux problèmes d'allergie tandis que l'érythrodermie ichtyosiforme englobe une peau rouge, enflammée et squameuse. Le syndrome de Netherton est héréditaire car il s'agit d'un trait autosomique récessif. La maladie est principalement due à des mutations associées au gène SPINK5. Dans certains cas, bien qu'il n'y ait pas d'antécédents familiaux de la maladie, le syndrome se révèle même lorsque deux parents sains porteurs du gène récessif muté ont un enfant, qui reçoit les deux copies du gène récessif. Le marché du syndrome de Netherton connaît une croissance énorme grâce à la sensibilisation croissante au syndrome de Netherton et au nombre croissant de lancements de produits. De plus, le nombre croissant d'essais cliniques et le solide portefeuille de produits constituent des opportunités importantes pour la croissance future des acteurs du marché. Cependant, le risque d'effets indésirables associés aux médicaments de traitement du syndrome de Netherton freine la croissance du marché.



Régions lucratives sur le marché mondial du syndrome de Netherton



Aperçu du marché



Nombre croissant de campagnes de sensibilisation au syndrome de Netherton pour stimuler la croissance



Le syndrome de Netherton est une affection cutanée rare autosomique récessive qui affecte les cheveux, la peau et le système immunitaire. La maladie affecte généralement les nouveau-nés chez qui la peau est généralement rouge et squameuse ainsi que des fuites de liquide dans certains cas. Les patients souffrant de cette maladie ne sont généralement pas au courant des options de traitement disponibles et n'ont pas un accès facile et des informations suffisantes concernant les soins à prendre. Les campagnes de sensibilisation ont un impact en ce sens qu'elles permettent un diagnostic rapide et précis. Ainsi, diverses organisations médicales et sociales œuvrent à la sensibilisation et à l'aide aux patients atteints du syndrome de Netherton à travers le monde.



Foundation for Ichtyosis& Related Skin Types (FIRST) en collaboration avec le National Health Council (NHC) a développé une organisation qui vise à améliorer la vie et à rechercher des remèdes pour les patients touchés par l'ichtyose et les types de peau apparentés. L'organisation fournit des informations précises et opportunes sur le syndrome de Netherton et l'ichtyose qui aident les patients à répondre aux besoins sociaux, médicaux et éducatifs de la communauté des maladies. De plus, le groupe de soutien à l'ichtyose (ISG) vise à protéger et à préserver la santé et à soulager les patients touchés par l'ichtyose et d'autres affections associées. L'ISG fournit un dossier d'information, distribue des bulletins et des bulletins d'information, organise des camps résidentiels pour enfants et autres. Ainsi, les campagnes de sensibilisation et les programmes d'information des patients et d'autres personnes concernant le syndrome de Nethertons devraient augmenter la croissance du marché au cours des prochaines années.

Aperçus basés sur la thérapie



Sur la base de la thérapie, le marché mondial du syndrome de Netherton est segmenté en agents kératolytiques, stéroïdes et rétinoïdes oraux et topiques, inhibiteurs topiques de la calcineurine, thérapies biologiques et radiothérapies. En 2019, le segment des agents kératolytiques détenait la plus grande part de marché. La croissance de ce marché segmenté est attribuée à l'augmentation des lancements de produits et au solide portefeuille de produits existants. En outre, les activités stratégiques des prestataires de services telles que les collaborations, les fusions et acquisitions et les extensions visant à accélérer le calendrier des médicaments accélèrent encore la croissance du marché. Cependant, le segment de la thérapie biologique devrait enregistrer le TCAC le plus élevé du marché mondial du syndrome de Netherton au cours de la période 2020-2027.



Marché du syndrome de Netherton, par thérapie - 2019 et 2027



Perspectives stratégiques



Les lancements de produits et les collaborations de recherche sont les stratégies couramment adoptées par les entreprises pour étendre leur présence dans le monde et répondre à la demande croissante des consommateurs. Les acteurs du marché du syndrome de Netherton ont adopté la stratégie d'innovations de produits pour répondre à l'évolution de la demande des clients à travers le monde, ce qui leur permet également de conserver leur marque à l'échelle mondiale.



Marché du syndrome de Netherton - par thérapie



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  • Agents kératolytiques

  • Stéroïdes et rétinoïdes oraux et topiques

  • Inhibiteurs topiques de la calcineurine

  • Radiothérapies

  • Thérapies biologiques

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    Marché du syndrome de Netherton - par géographie




    • Amérique du Nord

      • États-Unis



    • Europe

      • France

      • Allemagne

      • Italie

      • Royaume-Uni

      • Espagne


    • Asie-Pacifique (APAC)

      • Japon




    Profils des entreprises




    • Lifemax Laboratories, Inc.

    • Azitra, Inc.

    • Sixera Pharma Ab

    • Dermelix Biotherapeutics

    • Matrisys Bioscience

    • Quoin Pharmaceuticals

    • Krystal Biotech, Inc.


    Report Coverage
    Report Coverage

    Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

    Segment Covered
    Segment Covered

    This text is related
    to segments covered.

    Regional Scope
    Regional Scope

    North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

    Country Scope
    Country Scope

    This text is related
    to country scope.

    Frequently Asked Questions


    What is Netherton syndrome?

    Netherton syndrome is a rare genetic disorder that presents the three following characteristics: Ichthyosiform erythroderma, a red, inflamed, scaly skin. Trichorrhexis invaginata – short, brittle, lustreless hair, Atopic diathesis – predisposition to allergy problems. Netherton syndrome is inherited as an autosomal recessive trait disease. The NS condition is caused by mutations in the SPINK5 gene that is found on the chromosome. In some cases, there is no family history of the disease. NS is revealed when two unaffected parents (recessive) and both are carriers of the mutated recessive gene have a child who receives both copies of the recessive gene.

    What are the driving factors for the Netherton syndrome market across the globe?

    The factors that are driving growth of the market are increasing number of Netherton syndrome awareness campaigns and growing number of product launches with robust pipeline. Moreover, strategic activities by the manufacturers are offering lucrative opportunities for the growth of the market.

    Who are the major players in the Netherton syndrome market?

    The Netherton syndrome market majorly consists of the players such as Lifemax Laboratories, Inc., Azitra, Inc., Sixera Pharma Ab, Dermelix Biotherapeutics, Matrisys Bioscience, Quoin Pharmaceuticals Ltd., and Krystal Biotech, Inc. among others.

    The List of Companies - Netherton Syndrome Market

    1. Lifemax Laboratories, Inc.
    2. Azitra, Inc.
    3. Sixera Pharma Ab
    4. Dermelix Biotherapeutics
    5. Matrisys Bioscience
    6. Quoin Pharmaceuticals Ltd.
    7. Krystal Biotech, Inc

    The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

    1. Data Collection and Secondary Research:

    As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

    Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

    1. Primary Research:

    The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

    For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

    A typical research interview fulfils the following functions:

    • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
    • Validates and strengthens in-house secondary research findings
    • Develops the analysis team’s expertise and market understanding

    Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

    • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
    • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

    Below is the breakup of our primary respondents by company, designation, and region:

    Research Methodology

    Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

    1. Data Analysis:

    Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

    • Macro-Economic Factor Analysis:

    We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

    • Country Level Data:

    Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

    • Company Profile:

    The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

    • Developing Base Number:

    Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

    1. Data Triangulation and Final Review:

    The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

    We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

    We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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