The blood collection tubes for liquid biopsy market is projected to reach US$ 256.26 million by 2028 from US$ 79.03 million in 2021; it is estimated to grow at a CAGR of 18.3% from 2021 to 2028.
Liquid biopsy is a noninvasive alternative to surgical biopsies, which allows doctors to gain significant information about the detected tumors. Cancer DNA traces detected in a blood sample can reveal which treatments are more suitable for a given patient. The possibility of circulating cell-free DNA (cfDNA) analysis through liquid biopsy has enabled the development of numerous specialized measurement techniques. In the last few years, there has been a surge in interest in the (pre-) analytical conditions of the liquid biopsy workflow.
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Blood Collection Tubes for Liquid Biopsy Market: Strategic Insights
Market Size Value in US$ 79.03 million in 2021 Market Size Value by US$ 256.26 million by 2028 Growth rate CAGR of 18.3% from 2021 to 2028 Forecast Period 2021-2028 Base Year 2021
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Blood Collection Tubes for Liquid Biopsy Market: Strategic Insights
| Market Size Value in | US$ 79.03 million in 2021 |
| Market Size Value by | US$ 256.26 million by 2028 |
| Growth rate | CAGR of 18.3% from 2021 to 2028 |
| Forecast Period | 2021-2028 |
| Base Year | 2021 |
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The blood collection tubes for liquid biopsy market is segmented on the basis of product, material, application, end user, and geography. The market, by geography, is broadly segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South and Central America. The report offers in-depth insights into the market, emphasizing parameters such as market trends, technological advancements, and market dynamics, along with the analysis of the competitive landscape of leading market players.
Lucrative Regions for Blood Collection Tubes for Liquid Biopsy Market
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- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
Market Insights
Increase in Prevalence of Cancer Drives Blood Collection Tubes for Liquid Biopsy Market Growth
Health systems across the world are witnessing a substantial increase in the prevalence of cancer. According to the World Health Organization (WHO), cancer is the second-leading cause of mortality worldwide. Moreover, the International Agency for Research on Cancer (IARC) states the global cancer burden reached 19.3 million cases and 9.96 million cancer deaths in 2020. According to the data published by the WHO, in 2019, ~9.6 million deaths were caused by cancer across the world. Further, prostate, lung, colorectal, liver, and stomach cancer are the most observed cancer types in men, while breast, colorectal, and cervical cancer are reported more commonly among women.
According to a study published by the National Cancer Institute, in 2021, the incidence of cancer in the US is likely to reach 1.9 million. In the US, ~0.6 million people were anticipated to die due to cancer in 2021. Moreover, as per data published by Cancer Research UK in 2020, ~0.16 million people in the UK die every year due to cancer. The Globocan report published in 2018 stated that there were 911,014 breast cancer cases and 310,577 deaths due to breast cancer in the world, of which 367,900 and 162,468 breast cancer cases were reported in China and India, respectively.
Liquid biopsies are used for diagnosing non-small cell lung cancer (NSCLC) and screening or as a companion diagnostic for other types of cancers such as colorectal, breast, gastrointestinal, prostate, and ovarian. Early prognosis, reduced cost, therapy monitoring, acquired drug resistance, detection of tumor heterogeneity, and patient comfort are the benefits of liquid biopsy over traditional cancer diagnostics approaches, as it eliminates the need for surgery. As a result, the preference for liquid biopsy is increasing in parallel with the rise in cancer prevalence. Liquid biopsy procedures contribute to an organization's strategy to detect cancer early and precisely, allowing for a quick treatment of cancer patients and enhancing survival rates among them. This factor will ultimately boost the demand for blood collection tubes for collecting samples for performing liquid biopsy procedures in the coming years.
Rise in Demand for Minimally Invasive Diagnostic Tests Contributes Significantly to Blood Collection Tubes for Liquid Biopsy Market Growth
There is a growing preference for minimally invasive or noninvasive tests among patients for diagnostic purposes. Liquid biopsy is possibly performed for early cancer and mutation detection, tumor monitoring throughout treatment, and recurrence monitoring. This technique uses a nonsurgical method in which blood samples are collected for testing. Researchers can trace all epigenetic and genetic changes in solid tumors using blood samples. Patients are at a lesser risk of infection and blood loss during liquid biopsies, and clinicians can readily conduct these tests multiple times. Moreover, patients prefer minimally invasive procedures as the advanced instruments used in such procedures allow for more delicate and complex work to be performed with lower risk, less pain, and minimal scarring. Moreover, it cuts down the cost and time required for diagnosing the conditions.
Due to technological advancements in feasibility and processing times, liquid biopsy has recently attracted considerable interest as a noninvasive alternative to tissue biopsy in cancer patients . CTCs, cfDNAs, exosomes, and microvesicles can also be detected in a blood sample, which is making blood-based liquid biopsies more popular. A traditional biopsy is a highly invasive procedure, and surgeons avoid putting the patient at risk. Hence, the growing need for safe and noninvasive cancer diagnostic techniques is fueling the blood collection tubes for liquid biopsy market progress.
Product Insights
Based on product, the global blood collection tubes for liquid biopsy market is segmented into Ccf DNA tubes, CfRNA tubes, CTC Tubes, GDNA tubes, and others. In 2021, the Ccf DNA tubes segment held the largest share of the market. The same segment is expected to register the highest CAGR in the market during 2021–2028. The ccfDNA tube is used to collect, store, and transport venous whole blood, as well as to stabilize DNA for extraction, cell-free DNA (ccfDNA) from plasma and genomic DNA (gDNA) from the nucleated cellular fraction. Clinical laboratories can use the ccfDNA tube to stabilize samples when they can't be processed on the same day of collection.
End User Insights
Based on end user, the blood collection tubes for liquid biopsy market is segmented into genetic diagnostic labs, R&D centers, conventional diagnostic centers, and others. The genetic diagnostic labs segment held the largest market share in 2021. It is further expected to hold a significant market share during the forecast period.
Blood Collection Tubes for Liquid Biopsy Market, by Product – 2021 and 2028
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- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
Product launches, and mergers and acquisitions are highly adopted strategies by the global blood collection tubes for liquid biopsy market players. A few of the recent key market developments are listed below:
In November 2021, PreAnalytiX GmbH launched the QIAsymphony PAXgene Blood ccfDNA Kit (CE-IVD) that fulfills the new EU IVDR requirements. The PAXgene Blood ccfDNA Tube (CE-IVD), along with the kit, has been verified and validated as an integrated workflow solution for standardized and reproducible ccfDNA processing in diagnostic laboratories requiring automated solutions. In February 2021, Biocept, Inc. announced a collaboration with Protean BioDiagnostics Inc. to investigate the ability of Biocept's Target SelectorTM molecular assay to obtain the EGFR status in NSCLC patients.
The demand for blood collection tubes for liquid biopsy decreased upon the onset of the COVID-19 pandemic in 2020. The unprecedented impact of COVID-19 has been far-reaching, and it is claimed to have a more severe impact on cancer patients. The restrictive measures imposed to lower the infection rate have profoundly limited the number of patients undergoing cancer screening, diagnosis, and treatment. Moreover, a surge in pressure due to the growing rate of hospitalization among COVID-19 patients led to the re-profiling of many hospitals and healthcare departments, including oncology clinics, for treating such patients. According to one of the studies, many diagnostic and treatment procedures were canceled or postponed in the world, which included ~2.3 million cancer surgeries.
Blood Collection Tubes for Liquid Biopsy – Market Segmentation
The global blood collection tubes for liquid biopsy market is segmented on the basis of product, material, application, and geography. Based on product, the market has been subsegmented into ccfDNA tubes, cfRNA tubes, CTC tubes, gDNA tubes, intracellular RNA tubes, and others. Based on material, the blood collection tubes for liquid biopsy market is bifurcated into glass and plastic. The blood collection tubes for liquid biopsy market, by application, is further segmented into in-vitro diagnostics (IVD) and research. The market, by geography, is broadly segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South and Central America.
Company Profiles
- PreAnalytix GmbH
- Biocept,Inc.
- F. HOFFMANN-LA ROCHE LTD
- STRECK
- Norgen Biotek Corp
- Exact Sciences Corporation
- Greiner AG
- MagBio Genomics, Inc.
- Zymo Research Corporation
- Apostle Sciences
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Product, Material, Application, End User
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, RoSCAM, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States
Frequently Asked Questions
Key factors driving the growth of the market are the increase in prevalence of cancer worldwide and rising demand for minimally invasive diagnostic tests are driving the market's growth. However, the lack of skilled professionals leading to inaccurate blood collection tubes for liquid biopsy analysis is hampering the market growth.
A liquid biopsy is a non-invasive, non-invasive alternative to surgical biopsies that allows doctors to learn a lot about a tumour by taking a blood sample. Cancer DNA traces in the blood can reveal which treatments are most likely to work for a given patient. The development of numerous specialised measurement techniques has resulted from the possibility of circulating cell-free DNA (cfDNA) analysis as a liquid biopsy. Over the last few years, there has been a surge in interest in the (pre-) analytical conditions of the liquid biopsy workflow.
Key players in the market are PreAnalytix GmbH, Biocept,Inc., F. HOFFMANN-LA ROCHE LTD, STRECK, Norgen Biotek Corp, Exact Sciences Corporation, Greiner AG, MagBio Genomics, Inc., Zymo Research Corporation, Apostle Sciences among others.
Technological advancements in blood collection tubes for liquid biopsy is likely to act as a trend the market growth in the coming years.
ccfDNA Tubes segment is growing in the blood collection tubes for liquid biopsy market.
Untapped Potential of Emerging Economies is likely to fuel the market growth in the coming years.
The List of Companies - Blood Collection Tubes for Liquid Biopsy Market
- PreAnalytix GmbH
- Biocept,Inc.
- F. HOFFMANN-LA ROCHE LTD
- STRECK
- Norgen Biotek Corp
- Exact Sciences Corporation
- Greiner AG
- MagBio Genomics, Inc.
- Zymo Research Corporation
- Apostle Sciences
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
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Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
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- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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