Circulating Tumor Cell (CTC) Market Size & Growth | Report 2028

Circulating Tumor Cell (CTC) Diagnostics Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Technology (CTC Detection and Enrichment Method, CTC Direct Detection Methods, and CTC Analysis), Application (Clinical/Liquid Biopsy and Research), and End User (Hospital and Clinics, Research and Academic Institutes, and Diagnostic Centers)

  • Report Code : TIPRE00026639
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 194
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The circulating tumor cell (CTC) diagnostics market is projected to reach US$ 3,656.38 million by 2028 from US$ 1,909.41 million in 2021; it is estimated to grow at a CAGR of 9.7% from 2021 to 2028.

Circulating tumor cells (CTCs) have tremendous potential in diagnosing and treating cancer. Many techniques have been developed and are under continuous improvement to enhance their efficacy of CTC detection, isolation, enrichment, and analysis. Mostly used approach for CTC detection and isolation is immune-based detection, whereby antibodies selectively bind cell surface antigens. Tumor cells express different cell surface markers than blood cells and are separated from the circulatory cells. CTCs help detect minor subgroups of cells present in the primary tissue, which might eventually cause treatment resistance or relapse of the disease. Hence, detecting and characterizing CTCs can become an inevitable step in treating solid tumor malignancies.

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Circulating Tumor Cell (CTC) Diagnostics Market: Strategic Insights

circulating-tumor-cell-ctc-diagnostics-market
Market Size Value inUS$ 1,909.41 million in 2021
Market Size Value byUS$ 3,656.38 million by 2028
Growth rateCAGR of 9.7% from 2021 to 2028
Forecast Period2021-2028
Base Year2021
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The circulating tumor cell (CTC) diagnostics market is segmented on the basis of technology, application, end-user, and geography. The market, by geography, is broadly segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South & Central America. The report offers insights and in-depth analysis of the market, emphasizing parameters such as market trends, technological advancements, and market dynamics, along with the analysis of the competitive landscape of the globally leading market players.       

Lucrative Regions for Circulating Tumor Cell (CTC) Diagnostics Market

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Market Insights

Rising Demand for Minimally Invasive Diagnostic Procedures to Drive Circulating Tumor Cell (CTC) Diagnostics Market Growth during Forecast Period

There is a growing preference for minimally invasive or noninvasive procedures among patients for diagnostic purposes. Early cancer detection, mutation detection, tumor monitoring throughout treatment, and recurrence monitoring are possible using circulating tumor cell diagnostics, which uses a noninvasive method. Researchers can trace all epigenetic and genetic changes in solid tumors using blood samples with circulating tumor cells. Patients are at a lesser risk with these tests, and clinicians can readily perform them multiple times. Patients prefer minimally invasive procedures because the advanced instruments used in such procedures allow for more delicate and complex work to be performed with lower risk, less pain, and less scarring.

Due to technological advancements in feasibility and processing times, circulating tumor cell diagnostics and liquid biopsy have recently attracted considerable interest as a noninvasive alternative to tissue biopsy in cancer patients. Liquid biopsy adoption will be aided by an increased understanding of improved minimally invasive cancer detection technologies. The market growth will be influenced by rising demand for noninvasive tools and laboratory acceptance of CTCs tests and liquid biopsy. A liquid biopsy is a noninvasive and simple alternative to surgical biopsies that allows doctors to discover a range of information about tumors from a simple blood sample. Blood tests are painless, noninvasive, bear no risks, and cut down the cost and time to diagnose a problem. In addition, CTCs, cfDNAs, exosomes, and microvesicles can be detected in a blood sample, making blood-based liquid biopsies more popular. Thus, the increased demand for minimally invasive diagnostic tests is spurring the market growth. 

Technology Insights               

Based on technology, the global circulating tumor cell (CTC) diagnostics market is segmented into CTC detection and enrichment method, CTC direct detection methods, and CTC analysis. In 2020, the CTC detection and enrichment segment held the largest share of the market. Moreover, the same segment is expected to register the highest CAGR in the market during 2021–2028. With the help of CTC diagnostics, individuals can be diagnosed early. Therefore, the adaption of these technologies is increasing, which is expected to drive the market during the forecast period.   

Application Insights

Based on application, the global circulating tumor cell (CTC) diagnostics market is bifurcated into clinical/liquid biopsy and research. In 2020, the research segment held a larger share of the market and the same segment is expected to register a higher CAGR in the market during 2021–2028. Owing to the rise in the detection and diagnosis of various medical conditions across the globe, the market is expected to grow in the future.

End-User Insights

Based on end-users, the circulating tumor cell (CTC) diagnostics market is segmented into hospital and clinics, research and academic institutes, and diagnostic centers. The research and academic institutes segment held the largest market share in 2021 and is expected to register the highest CAGR in the market during the forecast period. The increasing research on cancer diagnosis and therapeutic development, growing awareness related to cancer diagnosis, and high investment from government and other enterprises are a few of the critical factors supporting the market growth for the Research and Academic Institutes segment.  

Circulating Tumor Cell (CTC) Diagnostics Market, by Technology – 2021 and 2028

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Circulating Tumor Cell (CTC) Diagnostics Market, by Technology – 2021 and 2028
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Product launches, and mergers and acquisitions are highly adopted strategies by the global circulating tumor cell (CTC) diagnostics market players. A few of the recent key market developments are listed below:

  • In January 2022, Thermo Fisher Scientific Inc. announced the complete acquisition of PeproTech for a total cash purchase price of approx. US$ 1.85 billion.
  • In December 2021, Epic Sciences, Inc. announced the launch of DefineMBC, a novel metastatic breast cancer (MBC) test that includes both cell-based and cell-free analysis from a single blood draw.

The COVID-19 pandemic had a negative impact on the people suffering from cancer and cancer surveillance capacities. Also, due to the pandemic, reduced resources and availability to care made cancer detection and treatment difficult, resulting in higher mortality, and lower survival. Due to a compromised immune system caused by cancer and/or its treatment, cancer patients are susceptible to infectious pathogens (e.g., surgery and chemotherapy). This has raised fears that COVID-19 problems and mortality may be common in cancer patients. Thus, the pandemic negatively impacts the circulating tumor cell (CTC) diagnostics market.

Circulating Tumor Cell (CTC) Diagnostics – Market Segmentation

The global circulating tumor cell (CTC) diagnostics market is segmented on the basis of technology, application, end-user, and geography. In terms of technology, the market is segmented into CTC detection and enrichment method, CTC direct detection methods, and CTC analysis. Based on application, the global circulating tumor cell (CTC) diagnostics market is bifurcated into clinical/liquid biopsy and research. Based on end-users, the circulating tumor cell (CTC) diagnostics market is segmented into hospital and clinics, research and academic institutes, and diagnostic centers. The market, by geography, is broadly segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South and Central America.

Company Profiles

  • Thermo Fisher Scientific Inc.
  • STEMCELL Technologies Inc.
  • QIAGEN
  • Precision Medicine Group, LLC.
  • Advanced Cell Diagnostics, Inc. (BIO-TECHNE CORPORATION)
  • Epic Sciences
  • ScreenCell
  • Ikonisys, Inc.
  • IVDiagnostics
  • Fluxion Biosciences Inc0
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Technology, Application, and End User

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions


What is the regional market scenario of sleep apnea diagnostics?

Global circulating tumor cell (CTC) diagnostics market is segmented by region into North America, Europe, Asia Pacific, Middle East & Africa and South & Central America. In North America, the U.S. is the largest market for sleep apnea diagnostics. The market growth in the country is attributed to the factors such as most foreign companies in the healthcare sector have R&D centres in the United States. Moreover, the increase in prevalence of cancer in the country along with various organic and inorganic developments done by the companies. And, Asia Pacific is the fastest-growing region growing at the CAGR of 10.3% during the forecast period.

Who are the key players in the circulating tumor cell (CTC) diagnostics market?

The circulating tumor cell (CTC) diagnostics market majorly consists of the players such as Thermo Fisher Scientific, Stemcell Technologies, Inc, QIAGEN, Precision Medicine Group, LLC, Advanced Cell Diagnostics (Bio-Techne Corporation), Epic Lifesciences, Screencell, Ikonisys, Inc, IV Diagnostics, Fluxion Biosciences, among others

Which application held the largest share in the circulating tumor cell (CTC) diagnostics market?

The research segment dominated the global circulating tumor cell (CTC) diagnostics market and accounted for the largest revenue share of 67.65% in 2021.

Which Technology led the circulating tumor cell (CTC) diagnostics market?

The CTC detection and enrichment method segment dominated the global circulating tumor cell (CTC) diagnostics market and held the largest revenue share of 62.85% in 2021.

What are the driving factors for the circulating tumor cell (CTC) diagnostics market across the globe?

Key factors that are driving the growth of this market are increasing prevalence of cancer across the globe along with rising demand for minimally invasive diagnostic procedures.

What is circulating tumor cell (CTC) diagnostics?

A Circulating Tumor Cell (CTC) is a cell that shed into lymphatics from the primary tumor and carried out throughout the body with blood circulation. Circulating tumor cells are the seeds for growth and metastases for additional tumors in distant organs and is responsible for majority of cancer related deaths. The diagnosis, detection and analysis of CTC can assist in patients’ prognoses determine appropriate tailored treatments for the patients. The CTC diagnosis has a lot of advantages for traditional diagnostic procedures. The advantages of CTC detection include, it is non-invasive, effective and can be used repeatedly. The CTC detection and enrichment, CTC direct detection and CTC analysis are the technologies used for CTC detection.

The List of Companies - Circulating Tumor Cell (CTC) Diagnostics Market

  1. Thermo Fisher Scientific Inc.
  2. STEMCELL Technologies Inc.
  3. QIAGEN
  4. Precision Medicine Group, LLC.
  5. Advanced Cell Diagnostics, Inc. (BIO-TECHNE CORPORATION)
  6. Epic Sciences
  7. ScreenCell
  8. Ikonisys, Inc.
  9. IVDiagnostics
  10. Fluxion Biosciences Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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