Crohns Disease Therapeutics Market Demand and Forecast | 2031

Crohn's Disease Therapeutics Market Size and Forecast (2021 - 2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Drug Class (Anti-inflammatory Drugs, Immune System Suppressors, Antibiotics, Biologics, Anti-diarrheal, and Pain Relievers), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and Geography

Publication Month : Mar 2024

  • Report Code : TIPRE00004296
  • Category : Pharmaceuticals
  • Status : Data Released
  • No. of Pages : 150
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[Research Report] The Crohn's disease therapeutics market was valued at US$ 9.68 billion in 2023 and is projected to reach US$ 13.33 billion by 2031. It is expected to register a CAGR of 4.1% in 2023–2031.

Market Insights and Analyst View:

Crohn's disease is a chronic inflammatory condition that primarily affects the gastrointestinal tract. It commonly affects the end part of the small intestine and the beginning of the large intestine. The disease is characterized by the inflammation of the digestive tract lining, leading to symptoms such as abdominal pain, diarrhea, and malnutrition. The growing Crohn's disease therapeutics market size is attributed to the increasing prevalence of diseases in Western countries, particularly the US. In addition, strategic initiatives by companies to stay competitive in the market are fueling market growth. A significant increase in the usage of advanced medical devices is likely to bring new Crohn's disease therapeutics market trends during the forecast period.

Growth Drivers and Challenges:

Crohn's disease is an irritable bowel syndrome, a chronic inflammatory bowel disorder with no specific cure. The exact etiology of this disease is not known, but the condition is mainly the result of an inappropriate immune response in the bowel to drugs, toxins, infections, and intestinal microbes, among other environmental factors, especially in a genetically susceptible host. According to National Library of Medicine, Crohn's disease (CD) is more common in developed countries in the West, especially in North American and northern European countries, and New Zealand. The disease onset is most common in individuals aged 15–30 years and 40–60 years, and it is more prominent in urban areas. The incidence of this disease is high in people from northern European countries and Jewish descent, i.e., 3.2/1,000. However, recent studies have shown a significant increase in incidence in Asia, Africa, and Australasia as well due to rapid industrialization in the region. Thus, the staggering prevalence of Crohn's disease in the respective region boosts the Crohn's disease therapeutics market.

According to National Institute of Health, Crohn's disease poses a significant economic burden with direct healthcare costs of approximately US$ 3,500 per patient per year in Europe. The disease affects approximately 322 people per 100,000. However, the prevalence rates may vary depending on countries to countries. More than 50% of patients with Crohn's disease may not be formally diagnosed, or they may show symptoms that are the same as those of other digestive tract diseases. Crohn's disease is more common in women as compared to men, i.e., it may affect three times more women than men.

Companies involved in drug development for irritable bowel syndrome are taking constructive steps to implement awareness programs with an aim to effectively cope with this syndrome by spreading awareness about symptoms, diagnoses, and treatments. In 2018, Allergan PLC and Ironwood, in collaboration, launched an Interactive Digital Destination platform to encourage sufferers to get educated and take action against digestive tract disorders. Thus, the rising prevalence of irritable bowel syndrome drives the Crohn's disease therapeutics market growth.

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Crohn's Disease Therapeutics Market: Strategic Insights

crohns-disease-therapeutics-market
Market Size Value inUS$ 9.68 billion in 2023
Market Size Value byUS$ 13.33 billion by 2031
Growth rateCAGR of 4.1% from 2023 to 2031
Forecast Period2023-2031
Base Year2023
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Report Segmentation and Scope:

The Crohn's disease therapeutics market analysis has been carried out by considering the following segments: drug type, distribution channel, and geography. By drug class, the market is segmented into anti-inflammatory drugs, immune system suppressors, antibiotics, biologics, anti-diarrheal, and pain relievers. The biologics segment held the largest market share in 2023. The anti-inflammatory drugs segment is expected to record the highest CAGR during 2023–2031.

Based on end user, the market is divided into hospital pharmacies, clinical pharmacies, and online others. The hospital pharmacy segment accounted for the largest Crohn's disease therapeutics market share in 2023. In terms of geography, the scope of the Crohn's disease therapeutics market report entails North America (US, Canada, and Mexico), Europe (Spain, UK, Germany, France, Italy, and Rest of Europe), Asia Pacific (South Korea, China, Japan, India, Australia, and Rest of Asia Pacific), Middle East & Africa (South Africa, Saudi Arabia, UAE, and Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America).

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Regional Analysis:

North America is the largest contributor to the global Crohn's disease therapeutics market growth. Asia Pacific is estimated to record the highest CAGR in the market during 2023–2031. The market progress in North America is attributed to the growing incidence of chronic diseases, technological advancements and access to technologically advanced medical products, the surging geriatric population, and the presence of key market players involved in new and existing product developments. The US held the largest Crohn's disease therapeutics market share in North America in 2023.

Crohn's Disease Therapeutics Market, by Distribution Channel – 2023 and 2031

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Industry Developments and Future Opportunities:

The Crohn's disease therapeutics market forecast is estimated on the basis of various secondary and primary research findings, such as key company publications, association data, and databases. As per the company press releases, key developments by major players operating in the Crohn's disease therapeutics market are listed below:

  • In 2023, the US Food and Drug Administration (FDA) approved the first oral pill—Rinvoq (upadacitinib)—to treat moderate-to-severe Crohn's disease. Rinvoq is meant to treat adult patients who could not be treated successfully with drug candidates blocking tumor necrosis factor (TNF).
  • In 2022, the FDA approved Skyrizi for the treatment of adults with moderate-to-severe active Crohn's disease cases.
  • In 2021, AbbVie Inc. announced the initiation of the Phase 3 trial of risankizumab for the treatment of Crohn's disease. Risankizumab is a humanized monoclonal antibody that selectively targets the interleukin-23 (IL-23) pathway. The trial is aimed at evaluating the efficacy and safety of risankizumab in patients with moderate-to-severe Crohn's disease.
  • In 2021, Takeda Pharmaceutical Company Limited announced the initiation of the Phase 3 trial of the oral compound TAK-721 for the treatment of Crohn's disease. TAK-721 is a selective antagonist of the chemokine receptor CXCR3. The trial is aimed at evaluating the efficacy and safety of TAK-721 in patients with moderate-to-severe Crohn's disease.

Competitive Landscape and Key Companies:

Abbvie, Inc.; Johnson and Johnson Private Limited; GlaxoSmithKline Plc; Merck and Co., Inc.; Novartis Ag; Celgene Corporation; Genentech; Pfizer Inc.; Nestle Health Science; and Boehringer Ingelheim GmbH are among the prominent players profiled in the Crohn's disease therapeutics market report. In addition, several other players have been studied and analyzed during the study to get a holistic view of the market and its ecosystem. These companies focus on geographic expansions and new product launches to meet the growing demand from consumers worldwide and expand their product range with specialty portfolios. Their global presence allows them to serve a large customer base, subsequently facilitating market expansion.

Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Drug Class, Distribution Channel, and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


Which segment is dominating the Crohn’s Disease Therapeutics Market?

The Crohn’s disease therapeutics market, based on drug class, is segmented into anti-inflammatory drugs, immune system suppressors, antibiotics, biologics, anti-diarrheal, and pain reliever. In 2023, the biologics segment held the largest Crohn’s disease therapeutics market share. The Crohn’s disease therapeutics market, by distribution channel, is segmented into hospital pharmacy, retail pharmacy, online pharmacy. In 2023, the hospital pharmacy segment held the largest Crohn’s disease therapeutics market share and is anticipated to record the highest CAGR during 2023–2031.

Who are the major players in market the Crohn’s Disease Therapeutics Market?

The Crohn’s Disease Therapeutics Market majorly consists of the players such Abbvie, Inc.; Johnson and Johnson Private Limited; GlaxoSmithKline Plc; Merck and Co., Inc.; Novartis Ag; Celgene Corporation; Genentech; Pfizer Inc.; Nestle Health Science; and Boehringer Ingelheim Gmbh

What is Crohn’s disease therapeutics Market?

Crohn's disease is a chronic inflammatory condition that primarily affects the gastrointestinal tract. It commonly affects the end part of the small intestine and the beginning of the large intestine. The disease is characterized by the inflammation of the digestive tract lining, leading to symptoms such as abdominal pain, diarrhea, and malnutrition. The growing Crohn's disease therapeutics market size is attributed to the increasing prevalence of diseases in Western countries, particularly the US. In addition, strategic initiatives by companies to stay competitive in the market are fueling market growth. A significant increase in the use of medical devices is likely to bring new Crohn's disease therapeutics market trends during the forecast period.

Which region is dominating the Crohn’s Disease Therapeutics Market?

Based on geography, the Crohn’s Disease Therapeutics Market is segmented into North America (the US, Canada, and Mexico), Europe (the UK, Germany, France, Italy, Spain, and the Rest of Europe), Asia Pacific (China, Japan, India, South Korea, Australia, and the Rest of Asia Pacific), the Middle East & Africa (the UAE, Saudi Arabia, South Africa, and Rest of the Middle East & Africa), and South & Central America (Brazil, Argentina, and the Rest of South & Central America). North America is the largest contributor to the growth of the global Crohn’s Disease Therapeutics Market. Asia Pacific is expected to register the highest CAGR in the Crohn’s Disease Therapeutics Market during 2023–2031.

What is the driving and restraining factors for the Crohn’s Disease Therapeutics Market?

The increasing burden of irritable bowel syndrome, and the increasing in number of FDA approval and drug development bolster the Crohn’s disease therapeutics market size. However, the high cost of the treatment hinders the Crohn’s disease therapeutics market growth.

The List of Companies - Crohn's Disease Therapeutics Market

  1. ABBVIE, INC.
  2. JOHNSON AND JOHNSON PRIVATE LIMITED
  3. GLAXOSMITHKLINE PLC
  4. MERCK AND CO., INC.
  5. NOVARTIS AG
  6. CELGENE CORPORATION
  7. GENENTECH
  8. PFIZER INC.
  9. NESTLe HEALTH SCIENCE
  10. BOEHRINGER INGELHEIM GMBH

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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