Glycomic Therapeutics Market Global Analysis & Forecast 2028

Glycomic Therapeutics Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Class (Isolated and Synthetic), Structures [Glycoproteins, Targeting Sialic Acid, Proteoglycans, Targeting Glycosaminoglycans, Glycosylphosphatidylinositol (GPI)-Anchored Proteins & Heparin Based Glycans, Targeting Glycosphingolipids, and Others], Indications (Thrombosis & Chemoprophylaxis, Anaemia, Anti-Adhesive & Anti-Inflammatory, Cataracts, Gaucher’s Disease, MPS-1 & IV, Cancer, Alzheimer’s Disease, Influenza Type A & B, and Others), and Mode of Action [Inhibits Neuraminidase; Inhibits Heparanase and Selectins and Blocks Interactions Between Growth Factors and Heparan Sulfate; Erythropoietin & Enzyme Replacement Therapy (ERT); Tissue Plasminogen Activator; Inhibits Glucosylceramide Synthase; Interleukin 1, 2 & 3; Beta & Gamma Interferons; and Others]

Publication Month : Aug 2022

  • Report Code : TIPRE00029576
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 330
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The glycomic therapeutics market is expected to grow from US$ 99,021.46 million in 2021 to US$ 257,578.79 million in 2028; it is estimated to grow with a CAGR of 15.8% from 2022 to 2028.

The report highlights prevailing trends and factors driving the market growth. Glycomics focuses on the structures and functions of complex carbohydrates, as found in glycoproteins, glycolipids, and glycosaminoglycans. Glycans are responsible for much of the structural variation in biological systems, and their representation on cell surfaces is commonly called the “glycome”. These glycans are present in many areas of the microbiome, including cell surfaces and proteins, and can be incredibly complex. Microbial glycomics is poised to revolutionize disease diagnosis, cancer detection, personalized medicine, antimicrobial vaccine, and drug discovery. As therapeutic agents, glycan-integrated nanomaterials can be used as a vaccine against viral and bacterial infections and cancer cells.

The report offers insights and in-depth analysis of the global glycomic therapeutics market, emphasizing various parameters, including market trends, technological advancements, market dynamics, and competitive landscape analysis of global leading market players. It also includes the impact of the COVID-19 pandemic on the market across all regions. The overall impact of the COVID-19 pandemic on the glycomic therapeutics market was mixed; hence, the market is still gaining traction and is expected to grow in the coming years. The health care systems were overburdened, and the delivery of medical care to all patients became a challenge. In addition, the biotechnology industry faced the undesirable impact of the pandemic. During the COVID-19 pandemic, medical device companies found difficulties managing their operations. Many companies of glycomic therapeutics had their business operations in the US, and the pandemic severely affected several businesses. However, after the pandemic restrictions normalized, the volume of surgical procedures returned to normal levels. Gradually hospitals resumed elective procedures as the COVID-19 recovery rate was increasing. The demand for glycan-based drugs in medical therapeutics and vaccine development applications has also increased.

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Glycomic Therapeutics Market: Strategic Insights

Market Size Value inUS$ 99,021.46 Million in 2021
Market Size Value byUS$ 257,578.79 Million in 2028
Growth rateCAGR of 15.8% from 2022 to 2028
Forecast Period2022-2028
Base Year2022
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Geography-Based Insights

By geography, the global glycomic therapeutics market is segmented into North America (the US, Canada, and Mexico), Europe (the UK, Germany, France, Italy, Spain, and the Rest of Europe), Asia Pacific (China, Japan, India, Australia, South Korea, and the Rest of Asia Pacific), the Middle East & Africa (the UAE, Saudi Arabia, South Africa, and the Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and the Rest of South & Central America).

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Market Insights

Increasing Research and Development in the Field of Glycomic Therapeutics

Glycans are exceedingly complex and found in many areas of the microbiome components, such as proteins and cell surfaces. Researchers and players are actively involved in the glycomics industry and are constantly focusing on technological developments to offer better alternatives to conventional techniques. A few examples of research & development in the glycomic therapeutics market are mentioned below:

  • In February 2022, the National Science Foundation (NSF) awarded ~US$ 23 million to a new multi-university partnership, jointly led by Virginia Tech and the University of Georgia, 2020, to accelerate glycomaterials research in the US. This partnership brought together top scientists and engineers from these institutions, along with Brandeis University, Rensselaer Polytechnic Institute, and the University of North Carolina at Chapel Hill, to establish a national glycomaterials research center.
  • In March 2022, Palleon Pharmaceuticals, a company pioneering the field of glycol-immunology to treat cancer and inflammatory diseases, announced the dosing of the first patient in the company’s Phase 1/2 study of E-602 in patients suffering from advanced cancers. The study, called GLIMMER-01 (Glycan-Immune Regulation), is the first clinical study of Palleon’s novel approach to cancer immunotherapy, which targets immunosuppressive sialoglycans.
  • In April 2022, CPTAC glycoproteomic researchers developed "Peptide-First" multi-attribute glycan identification method.
  • In March 2022, Japanese researchers uncovered the precise mechanism of a beta-1,2-glucan-associated enzyme to provide new information on complicated sugar metabolism. A team of researchers from Niigata University and Tokyo University of Science identified the structure and function of a new enzyme with glycosyltransferase activity. The findings of this investigation were made public on January 19, 2022, and were printed in the Journal of Biological Chemistry, Volume 298, Issue 3.
  • According to a study published in February 2022 by researchers at the University of Copenhagen's Center for Glycomics, Heparin can now be produced without using animals through glycomics studies.
  • In February 2022, GlycoMIP, a national research hub focused on glycomaterials research and led jointly by Virginia Tech and the University of Georgia, celebrated the grand opening of its national user facility with ribbon-cutting ceremonies at both universities. GlycoMIP will address nationwide bottlenecks in glycomaterial synthesis, computer modeling, material characterization, and knowledge sharing through ground-breaking research and a unique national user facility that will provide critical tools and services to the scientific community.

Such advancements in the field of glycomics propel the glycomic therapeutics market growth significantly.

Class-Based Insights

Based on the class, the glycomic therapeutics market is bifurcated into isolated and synthetic. In 2021, the synthetic segment accounted for a larger market share. However, the isolated segment is expected to register a higher CAGR of 16.3% during the forecast period.  

Glycomic Therapeutics Market, by Class – 2021 and 2028

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Structure-Based Insights

Based on structures, the glycomic therapeutics market is segmented into glycoproteins, targeting sialic acid, proteoglycans, targeting glycosaminoglcans, glycophosphatidylinositol (GPI)-anchored proteins & heparin based glycans, targeting glycosphingolipids, and others. The glycoproteins segment held the largest market share in 2021. However, the targeting sialic acid segment is anticipated to register the highest CAGR during the forecast period.

Indication-Based Insights

Based on indication, the glycomic therapeutics market is segmented into thrombosis & chemoprophylaxis, anemia, anti-adhesive & anti-inflammatory, cataract, Gaucher’s diseases, MPS-1 & IV, cancer, Alzheimer’s disease, influenza type A & B, and others. The influenza type A & B segment held the largest market share in 2021, and it is expected to continue a similar trend during the forecast period.

Mode of Action-Based Insights

Based on mode of action, the glycomic therapeutics market is segmented into inhibits neuraminidase; inhibits heparanase and selectins and blocks interactions between growth factors and heparan sulfate; erythropoietin & enzyme replacement therapy (ERT); tissue plasminogen activator; inhibits glucosylceramide synthase; interleukin 1, 2 & 3; beta & gamma interferons; and others. In 2021, the erythropoietin & enzyme replacement therapy (ERT) segment held the largest share of the market. However, the inhibits neuraminidase segment is expected to register the highest CAGR during the forecast period.

Intellihep Ltd; Protalix Biotherapeutics; BioMarin Pharmaceutical Inc.; Genzyme Corporation (Sanofi); Halozyme Therapeutics, Inc.; Bayer AG; Alzheon, Inc.; GlycoMar; GlaxoSmithKline plc.; and F. Hoffmann-La Roche Ltd are among the leading players operating in the glycomic therapeutics market. These companies have been implementing various strategies that have helped their growth, resulting in several developments in the market.

Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Class, Structures, Indications, and Mode of Action

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions

Which segment led the glycomic therapeutics market?

The synthetic segment under class segment held the largest market share in 2021.

Who are the key players in the glycomic therapeutics market?

The glycomic therapeutics market majorly consists of the players such as Intellihep Ltd; Protalix Biotherapeutics; BioMarin Pharmaceutical Inc.; Genzyme Corporation (Sanofi); Halozyme Therapeutics, Inc.; Bayer AG; Alzheon, Inc.; GlycoMar; GlaxoSmithKline plc.; and F. Hoffmann-La Roche Ltd.

Which region is fastest growing?

Based on geography, the APAC region is anticipated to witness the highest CAGR in glycomic therapeutics market during the forecast period.

What are the drivers and opportunities for the glycomic therapeutics market?

The growth of the market is attributed to wide application in various disorders followed by the development of new treatment processes, increasing research and development in the field of glycomic therapeutics, and expanding R&D investments and rising use of glycomics in various diseases leading to development of new treatment processes.

The List of Companies - Glycomic Therapeutics Market

  1. Intellihep Ltd
  2. Protalix Biotherapeutics
  3. BioMarin Pharmaceutical Inc.
  4. Genzyme Corporation (Sanofi)  
  5. Halozyme Therapeutics, Inc.       
  6. Bayer AG            
  7. Alzheon, Inc.     
  8. GlycoMar
  9. GlaxoSmithKline plc.      
  10. F. Hoffmann-La Roche Ltd 

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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