Human Microbiome Market Size, Share | Report 2021, 2028

Human Microbiome Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Product (Probiotics, Foods, Prebiotics, Medical Foods, Diagnostic Device, Drugs and Supplements), Disease (Obesity, Diabetes, Autoimmune Disorders, Cancer, Mental Disorders, and Others) and Application (Therapeutics and Diagnostics) and Geography

Publication Month : Aug 2021

  • Report Code : TIPBT00002233
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 188
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The human microbiome market is expected to reach US$ 2,921.68 million by 2028 from US$ 718.95 million in 2021; it is estimated to grow at a CAGR of 22.2% during 2021–2028.

The human microbiota consists of the trillions of symbiotic microbial cells harbored by each person mainly bacteria in the gut. The microbes, including bacteria, fungi, and viruses, are the disease-causing agent that accumulate over time, and the habitat in gut transforms their genetic activities and metabolic processes, resulting in an abnormal immune response against the substances and tissues that normally present in the human body. Several microbiome projects have been launched worldwide with the aim to understand the roles played by these symbionts and their impact on the health of human host. The growth of the human microbiome market is attributed to the factors such as increasing incidence of lifestyle diseases, increasing focus on human microbiome therapies, and growing technological advancements in metagenomics and next-generation sequencing. However strict government guidelines and lack of knowledge about detailed examination hinders the market growth.  

Lucrative Regions for Human Microbiome Market

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Market Insights

Increasing Incidence of Lifestyle Diseases

In the past few decades, researchers have come up with the clarity on the relation between human microbiome and lifestyle diseases such as cancer, diabetes, obesity, and depression. Changes in lifestyles and societal norms influence the microbiome at each stage of life. Altering the human microbiome can help eliminate such lifestyle diseases. As per World Health Organization, 13% of the world population (adults) was obese in 2016. According to the “The New Era of Treatment for Obesity and Metabolic Disorders: Evidence and Expectations for Gut Microbiome Transplantation,” published in 2016, microbes residing in the human gastrointestinal tract act as an endocrine organ whose composition and functionality contribute to the development of obesity. Therefore, fecal/gut microbiome transplantation (GMT), involving the transfer of feces from a healthy donor to the patient, is a potential treatment for obesity.

Diabetes is one of the global health emergencies of the 21st century. According to the International Diabetes Federation (IDF), the number of people suffering from diabetes in North America was ~46 million in 2017, which is expected to rise to 62 million by 2045, i.e., with the disease prevalence of ~35% during the forecast period. The reduced levels of Firmicutes Clostridia indicate the microbiome of patients with diabetes butyrate-producing bacteria and an increased ratio of Bacteroidetes: Firmicutes. Thus, diabetes can be prevented as well as treated by altering the microbiome by administration of prebiotics, probiotics, and fecal transplantation. Therefore, the increasing incidence of chronic lifestyle diseases is driving the human microbiome market growth.

Product-Based Insights

Based on product, the human microbiome market is segmented into foods, medical foods, probiotics, prebiotics, drugs, diagnostic devices, and supplements. The probiotics segment is projected to hold the largest market share in 2021, and the prebiotics segment is anticipated to register the highest CAGR in the market during the forecast period.

Human Microbiome Market, by Product – 2021 and 2028

Human Microbiome Market, by Product – 2021 and 2028
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Report Coverage

Disease-Based Insights

The human microbiome market, by disease, is segmented into diabetes, cancer, autoimmune disorders, obesity, mental disorders, and other diseases. The market for the human microbiome is emerging owing to rising incidences of lifestyle diseases such as cancer and diabetes. The obesity segment is expected to hold the largest share of the market in 2021, whereas the diabetes segment is estimated to register the highest CAGR during the forecast period.

Application-Based Insights

The human microbiome market, by application, is segmented into diagnostics and therapeutics. The therapeutics segment is projected to hold a larger market share in 2021, and it is further estimated to register a higher CAGR during the forecast period.

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Human Microbiome Market: Strategic Insights

Market Size Value inUS$ 718.95 Million in 2021
Market Size Value byUS$ 2,921.68 Million by 2028
Growth rateCAGR of 22.2% from 2021-2028
Forecast Period2021-2028
Base Year2021
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Product launches and approvals are the commonly adopted strategies by companies to expand their global footprints and product portfolios. Companies in the human microbiome market focus on the collaboration strategy to enlarge their clientele, which, in turn, permits them to maintain their brand name across the world.

Human Microbiome Market – by Product

  • Probiotics 
  • Foods
  • Prebiotics
  • Medical Foods
  • Diagnostic Devices
  • Drugs
  • Supplements

Human Microbiome Market – by Disease  

  • Obesity
  • Diabetes
  • Autoimmune Disorders
  • Cancer
  • Mental Disorders
  • Others

 Human Microbiome Market – by Application   

  • Therapeutics
  • Diagnostics

Human Microbiome Market – by Geography

  • North America

    • US
    • Canada
    • Mexico
  • Europe

    • France
    • Germany
    • Italy
    • UK
    • Spain
    • Rest of Europe
  • Asia Pacific (APAC)

    • China
    • India
    • South Korea
    • Japan
    • Australia
    • Rest of Asia Pacific
  • Middle East and Africa (MEA)

    • South Africa
    • Saudi Arabia
    • UAE
    • Rest of Middle East and Africa
  • South and Central America (SCAM)

    • Brazil
    • Argentina
    • Rest of South and Central America

Company Profiles

  • Rebiotix Inc.
  • Yakult Honsha Co., Ltd.
  • Synthetic Biologics Inc.
  • DuPont
  • MaaT Pharma
  • Eligo Bioscience
  • Merck & Co. Inc
  • AOBiome LLC
  • Kaleido
  • Seres Therapeutics
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Product , Disease and Application and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, RoAPAC, RoE, RoMEA, RoSCAM, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions

What is the regional analysis in terms of human microbiome market?

The Asia Pacific human microbiome market is analyzed based on the five major countries such as China, Japan, India, Australia, South Korea, and the rest of Asia Pacific. The Asia Pacific region is expected to be the fastest-growing region among all other regions. The rise in the collaborations among the Asian countries and Western countries for the research activities and the extensive genomic research in China are to likely drive the human microbiome market in the forecast period. In May 2018, The Conference on Human Microbiome and Chronic Disease, hosted by the Institute of Microbiology, Chinese Academy of Sciences and Chinese Society of Biotechnology was held in China National Convention Center at Beijing. The aim was to promote research human microbiome and related technology. Thus, there is a huge potential for human microbiome market in the region during the forecast period owing to the above-mentioned factors.

What are the driving factors for the human microbiome market across the globe?

The growth of the human microbiome market is attributed to the factors such as increasing incidence of lifestyle diseases, increasing focus on human microbiome therapies, and growing technological advancements in metagenomics and next-generation sequencing. However strict government guidelines and lack of knowledge about detailed examination hinders the market growth.

What is human microbiome?

The human microbiota consists of the trillions of symbiotic microbial cells harbored by each person, mainly bacteria in the gut. The microbes including bacteria, fungi and viruses are the disease-causing microbes that accumulate over time and changing their gene activity & metabolic processes and resulting in an abnormal immune response against the substances and tissues that normally present in the human body.

The List of Companies - Human Microbiome Market

  1. Rebiotix Inc.
  2. Yakult Honsha Co., Ltd.
  3. Synthetic Biologics Inc.
  4. DuPont
  5. MaaT Pharma
  6. Eligo Bioscience
  7. Merck & Co. Inc
  8. AOBiome LLC
  9. Kaleido
  10. Seres Therapeutics

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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