Label Free Detection Market Size, Analysis & Forecast to 2028

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Label Free Detection Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Product (Instruments and Consumables), Technology (Surface Plasmon Resonance, Bio-Layer Interferometry, Isothermal Titration Calorimetry, Differential Scanning Calorimetry, and Other LFD Technologies), Application (Binding Kinetics, Binding Thermodynamics, Endogenous Receptor Detection, Hit Confirmation, Lead Generation, and Other Applications), and End User (Pharmaceutical & Biotechnology Companies, Academic & Research Institutes, Contract Research Organizations, and Other End Users)

Publication Month: Feb 2022 | Report Code: TIPBT00002548 | No. of Pages: No. of Pages198 | Category: Biotechnology | Status: Published

The label free detection market is projected to reach US$ 829.71 million in 2028 from US$ 474.82 million in 2021; it is estimated to grow at a CAGR of 8.3% from 2021 to 2028.

Label-Free Detection (LFD) is a technique used for discovering biomolecules and their interactions. This method has emerged as an attractive research and development tool in the pharmaceutical and biotech industry. Label-free technology uses impedance- or optics-based biosensors to measure the changes upon analyte binding to a ligand immobilized on a biosensor surface. This approach enables the interaction to be monitored in real-time without manipulating the individual assay components artificially. A defining feature of label-free technology is the method used for ligand immobilization.

Strategic Insights

Report Coverage - Label Free Detection Market
Report CoverageDetails
Market Size Value inUS$ 474.82 Million in 2021
Market Size Value byUS$ 829.71 Million in 2028
Growth rateCAGR of 8.3% from 2021 to 2028
Forecast Period2021-2028
Base Year2021
No. of Pages198
No. of Tables110
No. of Charts & Figures82
Historical data availableYes
Segments coveredProduct, Technology, Application, and End User
Regional scopeNorth America; Europe; Asia Pacific; Latin America; MEA
Country scopeUS, UK, Canada, Germany, France, Italy, Australia, Russia, China, Japan, South Korea, Saudi Arabia, Brazil, Argentina
Report coverageRevenue forecast, company ranking, competitive landscape, growth factors, and trends
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The label free detection market is segmented on the basis of product, technology, application, end user and geography. The market, by geography, is broadly segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South & Central America. The report offers insights and in-depth analysis of the market, emphasizing parameters such as market trends, technological advancements, and market dynamics, along with the analysis of the competitive landscape of the globally leading market players.   

Lucrative Regions for Label Free Detection Market

Lucrative Regions for Label Free Detection Market

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Market Insights

Growing Number of Drug Discovery Programs through Academic–Industrial Partnerships to Drive Label Free Detection Market Growth during Forecast Period

Direct partnerships between pharma/biotech companies and academic centers are becoming prevalent. For academic researchers and researchers in pharma, the benefits of these partnerships are evident. Financial support from pharma provides steady funding and increases their opportunity to do impactful work. These collaborations may begin as funding for academic research for promising candidates. The strategy helps pharmaceutical companies fill gaps in their portfolio at lower costs and risks. A few examples of innovative academic–industrial collaborations are—Takeda Pharmaceuticals with Kyoto University in Japan and Stanford University in the US and Sanofi with the University of California, San Francisco (the US). In 2020, Creoptix collaborated with Professor Adriano Aguzzi and the University of Zurich to analyze SARS-CoV-2 antibodies in COVID-19 patients using the Creoptix WAVE system. Therefore, the growing number of drug discovery programs through academic–industrial partnerships propels the growth of the label free detection market.

Product Insights           

Based on product, the global label free detection market is segmented into instruments and consumables. In 2021, the consumable segment held the largest share of the market. Moreover, the same segment is expected to register the highest CAGR in the market during 2021–2028, owing to the factors such as continuous advancements in label free detection technologies, and rising government investments to advance the developments in biopharmaceutical, and biotechnology sectors.

Technology Insights

Based on technology, the global label free detection market is segmented into surface plasmon resonance, bio-layer interferometry, isothermal titration calorimetry, differential scanning calorimetry, and other LFD technologies. In 2021, the surface plasmon resonance technology segment held the largest share of the market. Moreover, the same segment is expected to register the highest CAGR in the market during 2021–2028. This growth is owing to the great sensitiveness of this technology and its extensive application in regulating specificity, affinity, and kinetic parameters at the time of the binding of macromolecules.

Application Insights

Based on application, the global label free detection market is segmented into binding kinetics, binding thermodynamics, endogenous receptor detection, hit confirmation, lead generation, and other applications. In 2021, the binding kinetics segment held the largest share of the market. Moreover, the same segment is expected to register the highest CAGR in the market during 2021–2028. The factors attributing the growth of this segment are rising need of drugs with broad therapeutic index, advancements in structural biology and growing R&D activities to detect corona virus with label free detection method. 

End-User Insights

Based on end-users, the global label free detection market is segmented into pharmaceutical & biotechnology companies, academic & research institutes, contract research organizations and other end users. In 2021, the pharmaceutical and biotechnology companies segment held the largest market share in 2021. Moreover, the same segment is expected to register the highest CAGR in the market during 2021–2028. This growth is owing to the extensive use of label-free detection technologies by pharmaceutical & biotechnology companies for studying biomolecular interactions in drug discovery.

Label Free Detection Market, by Product – 2021 and 2028

Label Free Detection Market, by Product – 2021 and 2028           

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Product launches, and collaborations are highly adopted strategies by the global label free detection market players. A few of the recent key market developments are listed below:

  • In August 2021, Agilent Technologies Inc. announced the launch of the Agilent Seahorse XF Pro Analyzer, featuring new pharma-oriented workflow solutions incorporating advanced experimental design and analysis tools.
  • In January 2022, Waters Corporation announced that it has acquired the technology assets and intellectual property rights of Megadalton Solutions, Inc., an early-stage developer of Charge Detection Mass Spectrometry (CDMS) technology and services.

The overall impact of COVID-19 on North America’s label free detection market is positive. There have been various factors, including increased incidences of COVID-19 positive patients, growth in research, increasing production of vaccines, outcome study of administered vaccine, and many other factors. For instance, a research published in Journal of American Chemical Society (JACS) showed the label-free digital detection of intact virions. The study revealed that the label-free biosensing method rapidly detected and quantified intact virus in human saliva with single-virion resolution. The cases majorly led to the demand for new diagnostic methods in the countries like the US, Canada, and Mexico. Thus, the label free detection market in North America is positively impacted by COVID-19.

Label Free Detection – Market Segmentation

The global label free detection is segmented on the basis of product, technology, application, end user and geography. In terms of product, the market is segmented into instruments and consumables. Based on technology, the label free detection market is segmented into surface plasmon resonance, bio-layer interferometry, isothermal titration calorimetry, differential scanning calorimetry, and other LFD technologies. Based on application, the market is segmented into binding kinetics, binding thermodynamics, endogenous receptor detection, hit confirmation, lead generation, and other applications. Based on end-users, the label free detection market is segmented into pharmaceutical & biotechnology companies, academic & research institutes, contract research organizations and other end users. The market, by geography, is broadly segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South and Central America.  

Company Profiles

  • General Electric
  • Perkin Elmer, Inc.
  • AMETEK Inc.
  • F. HOFFMANN-LA ROCHE LTD
  • Spectris
  • METTLER TOLEDO
  • Agilent Technologies, Inc.
  • Waters Corporation
  • Sartorius AG
  • Corning Incorporated

Frequently Asked Questions

Label-Free Detection (LFD) is a technique used for discovering biomolecules and their interactions. This method has emerged as an attractive research and development tool in the pharmaceutical and biotech industry. Label-free technology uses impedance- or optics-based biosensors to measure the changes upon analyte binding to a ligand immobilized on a biosensor surface. This approach enables the interaction to be monitored in real-time without manipulating the individual assay components artificially. A defining feature of label-free technology is the method used for ligand immobilization.
The factors that are driving and restraining factors that will affect the label free detection market in the coming years. Factors such as the introduction of high-tech products, and growing number of drug discovery programs through academic-industrial partnerships are driving the market. However, the high cost of LFD instruments is hampering the market growth.
The label free detection market majorly consists of the players such as General Electric; Perkin Elmer, Inc.; AMETEK Inc.; F. HOFFMANN-LA ROCHE LTD; Spectris; METTLER TOLEDO; Agilent Technologies, Inc.; Waters Corporation; Sartorius AG; Corning Incorporated.
The global label free detection market based on product, is segmented into instruments and consumables. The consumables held the largest share of the market in 2021 and the same segment register the highest CAGR during the forecast period.

The List of Companies - Label Free Detection Market

  1. General Electric
  2. Perkin Elmer, Inc.
  3. AMETEK Inc.
  4. F. HOFFMANN-LA ROCHE LTD
  5. Spectris
  6. METTLER TOLEDO
  7. Agilent Technologies, Inc.
  8. Waters Corporation
  9. Sartorius AG
  10. Corning Incorporated
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  • Scrutinize in-depth global market trends and outlook coupled with the factors driving the market, as well as those hindering it.
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