The native bacterial and viral antigens market is expected to reach US$ 28,801.15 thousand by 2027 from US$ 17,105.05 thousand in 2019; it is estimated to grow at a CAGR of 6.8% from 2020 to 2027.
Native antigens are extracted in their natural form from the respective sources. As they undergo usual modifications in vivo, upon isolation, they exhibit close resemblance withthe complex 3-dimensional structure they exhibit in the host. In the case of protein antigens, these modifications may include post-translational alterations such as cleavage of precursor proteins, formation of disulphide bonds, and addition of low molecular weight groups through processes such as glycosylation or phosphorylation. The global native bacterial and viral antigens market is driven by factors such as increasing use of native microbial antigens in diagnostics and therapeutics, and rising prevalence of infectious diseases. However, the limitations associated with native antigens such as high cost, low antigen production levels, and scale-up difficultieshinder the market growth.However, emerging markets are creating growth opportunities for the market players.
Lucrative Regional Markets for Native Bacterial and Viral Antigens
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Market Insights
Increasing Use of Native Microbial Antigens in Diagnostics and Therapeutics
Antigens are the biomolecules that are capable of triggering immune response in host body through the activation of lymphocytes. Bacterial antigens are used in the development of various types of antibodies in research laboratories for the improvement of immune systems. Moreover, bacterial antigens are also widely used in immunodiagnostic assays such as ELISA.
Panning of native antigen libraries have led to development of potent neutralization antibodies against various bacterial and viral infections. The native antigens are extracted in their natural form from a corresponding source. There is high demand for a large number of native antigens, especially in in vitro diagnostics and vaccine research. According to various scientific studies, recombinant antigens exhibit solubility and aggregation issues. Further, the association of recombinant antigens with non-protein entities is also different and sometimes lacking in terms of performance as compared to native antigens.
With the recent outbreak of COVID-19, companies are developing commercial SARS-CoV-2 antigens to support the vaccine formulation, and research and development to strengthen the disease diagnosis and therapy. In February 2020, the Native Antigen Company became the first company to commercially provide the novel coronavirus antigens, using the company’s proprietary VirtuE (HEK293) expression system. Thus, the rising use of native antigens, effectively supporting the diagnostics and therapeutics of various medical conditions, boosts the growth of the native bacterial antigen and antibody market.
Product Type-Based Insights
The native bacterial and viral antigens market,based on product type, is segmented into chlamydia antigens, adenovirus antigens, borrelia antigens, clostridium antigens, chikungunya virus antigens, and dengue virus antigens. The chlamydia antigens segment held the largest share of the market in 2019, and the market for the same is anticipated to grow at the highest CAGR during the forecast period. Growth of the market for this segment is attributed to easy availability of these antigens, with majority of the market players commercially offering these antigens in the native forms. Further, the use of chlamydiaantigens in research institutes and laboratories for the development of vaccines and in vitro diagnostics (IVD) tests is further expected to propel the growth of the market for this segment.
Native Bacterial and Viral Antigens Market, by Technology– 2018 and 2027
- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
Pathogen Type-Based Insights
Based on pathogen type, the native bacterial and viral antigens market is segmented into inactivated pathogen and purified pathogen. The inactivated pathogen segment held a larger share of the market in 2019, and it is estimated to register a higher CAGR during the forecast period.
Application-Based Insights
Based on application, the native bacterial and viral antigens market is segmented into ELISA, immunoassay, SDS-PAGE, hemagglutination, and agglutination tests. The ELISA segment held the largest share of the market in 2019 and is estimated to register the highest CAGR during 2020–2027.
End User-Based Insights
Based on end user, the native bacterial and viral antigens market is segmented into diagnostic laboratories and centers and academic and research institutes. The diagnostic laboratories and centers segment held the largest share of the market in 2019, and it is estimated to register the highest CAGR from 2020 to 2027.
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Native Bacterial and Viral Antigens Market: Strategic Insights
Market Size Value in US$ 17,105.05 thousand in 2019 Market Size Value by US$ 28,801.15 thousand by 2027 Growth rate CAGR of 6.8% from 2020-2027 Forecast Period 2020-2027 Base Year 2020
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Native Bacterial and Viral Antigens Market: Strategic Insights
| Market Size Value in | US$ 17,105.05 thousand in 2019 |
| Market Size Value by | US$ 28,801.15 thousand by 2027 |
| Growth rate | CAGR of 6.8% from 2020-2027 |
| Forecast Period | 2020-2027 |
| Base Year | 2020 |
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Product launches and approvalsare the commonly adopted strategies by companies to expand their global footprintsand product portfolios; these strategies help them meet the growing consumer demand. Collaboration is one of the major strategies adopted by the companies operating in the native bacterial and viral antigens market to enlarge customer base worldwide, which also permits them to maintain their brand name globally.
Native Bacterial and Viral Antigens Market – byProduct Type
- Chlamydia Antigens
- Adenovirus Antigens
- Borrelia Antigens
- Chikungunya Virus Antigens
- Clostridium Antigens
- Dengue Virus Antigens
Native Bacterial and Viral Antigens Market – by Pathogen Type
- Inactivated Pathogen
- Purified Pathogen
Native Bacterial and Viral Antigens Market – by Application
- ELISA
- Immunoassay
- SDS-PAGE
- Hemagglutination
- Agglutination Test
Native Bacterial and Viral Antigens Market – by EndUser
- Diagnostic Laboratories and Centers
- Academic and Research Institutes
Native Bacterial and Viral Antigens Market– by Geography
North America
- US
- Canada
- Mexico
Europe
- France
- Germany
- Italy
- UK
- Spain
- Rest of Europe
Asia Pacific (APAC)
- China
- India
- South Korea
- Japan
- Australia
- Rest of Asia Pacific
Middle East and Africa (MEA)
- South Africa
- Saudi Arabia
- UAE
- Rest of Middle East and Africa
South and Central America
- Brazil
- Argentina
- Rest of South America
Company Profiles
- BIO-RAD LABORATORIES INC.
- Microbix Biosystems
- SERION Immunologics
- Aalto Bio Reagents Ltd
- Enzo Life Sciences Inc.
- Jena Bioscience GmbH
- ROSS SOUTHERN LABORATORIES
- The Native Antigen Company
- Creative Diagnostics
- TRINA BIOREACTIVES AG
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Product Type , Pathogen Type ; Application , End User , and Geography
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States
Frequently Asked Questions
Native antigens are extracted in their natural form from an appropriate source. Because they have undergone the usual modifications that would occur in vivo, they bear a very close resemblance when isolated to the complex 3-dimensional structure they exhibit in the host. In the case of protein antigens, these modifications can include post-translational alterations such as cleavage of precursor proteins, formation of disulphide bonds, and addition of low molecular weight groups through processes such as glycosylation or phosphorylation.
Factors such as increasing use of native microbial antigens in diagnostics and therapeutics, and rising prevalence of infectious diseases drive the growth of the market.Moreover, developments in emerging markets is expected to offer lucrative opportunities for the growth of the market.
The native bacterial and viral antigensmarket majorly consists of the players such as BIO-RAD LABORATORIES, INC., Microbix Biosystems, SERION Immunologics, Aalto Bio Reagents Ltd., Enzo Life Sciences, Inc., Jena Bioscience GmbH, ROSS SOUTHERN LABORATORIES, The Native Antigen Company, Creative Diagnostics, and TRINA BIOREACTIVES AG amongst others.
The List of Companies - Native Bacterial and Viral Antigens Market
- BIO-RAD LABORATORIES INC.
- Microbix Biosystems
- SERION Immunologics
- Aalto Bio Reagents Ltd
- Enzo Life Sciences Inc.
- Jena Bioscience GmbH
- ROSS SOUTHERN LABORATORIES
- The Native Antigen Company
- Creative Diagnostics
- TRINA BIOREACTIVES AG
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Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
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- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
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- Data Triangulation and Final Review:
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