Native Bacterial and Viral Antigens Market Drivers and Forecasts by 2027

The native bacterial and viral antigens market is expected to reach US$ 28,801.15 thousand by 2027 from US$ 17,105.05 thousand in 2019; it is estimated to grow at a CAGR of 6.8% from 2020 to 2027.

Native antigens are extracted in their natural form from the respective sources. As they undergo usual modifications in vivo, upon isolation, they exhibit close resemblance withthe complex 3-dimensional structure they exhibit in the host. In the case of protein antigens, these modifications may include post-translational alterations such as cleavage of precursor proteins, formation of disulphide bonds, and addition of low molecular weight groups through processes such as glycosylation or phosphorylation. The global native bacterial and viral antigens market is driven by factors such as increasing use of native microbial antigens in diagnostics and therapeutics, and rising prevalence of infectious diseases. However, the limitations associated with native antigens such as high cost, low antigen production levels, and scale-up difficultieshinder the market growth.However, emerging markets are creating growth opportunities for the market players.

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Native Bacterial and Viral Antigens Market: Strategic Insights

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Market Insights

Increasing Use of Native Microbial Antigens in Diagnostics and Therapeutics

Antigens are the biomolecules that are capable of triggering immune response in host body through the activation of lymphocytes. Bacterial antigens are used in the development of various types of antibodies in research laboratories for the improvement of immune systems. Moreover, bacterial antigens are also widely used in immunodiagnostic assays such as ELISA.
Panning of native antigen libraries have led to development of potent neutralization antibodies against various bacterial and viral infections. The native antigens are extracted in their natural form from a corresponding source. There is high demand for a large number of native antigens, especially in in vitro diagnostics and vaccine research. According to various scientific studies, recombinant antigens exhibit solubility and aggregation issues. Further, the association of recombinant antigens with non-protein entities is also different and sometimes lacking in terms of performance as compared to native antigens.
With the recent outbreak of COVID-19, companies are developing commercial SARS-CoV-2 antigens to support the vaccine formulation, and research and development to strengthen the disease diagnosis and therapy. In February 2020, the Native Antigen Company became the first company to commercially provide the novel coronavirus antigens, using the company’s proprietary VirtuE (HEK293) expression system. Thus, the rising use of native antigens, effectively supporting the diagnostics and therapeutics of various medical conditions, boosts the growth of the native bacterial antigen and antibody market.

Product Type-Based Insights

The native bacterial and viral antigens market,based on product type, is segmented into chlamydia antigens, adenovirus antigens, borrelia antigens, clostridium antigens, chikungunya virus antigens, and dengue virus antigens. The chlamydia antigens segment held the largest share of the market in 2019, and the market for the same is anticipated to grow at the highest CAGR during the forecast period. Growth of the market for this segment is attributed to easy availability of these antigens, with majority of the market players commercially offering these antigens in the native forms. Further, the use of chlamydiaantigens in research institutes and laboratories for the development of vaccines and in vitro diagnostics (IVD) tests is further expected to propel the growth of the market for this segment.

Pathogen Type-Based Insights

Based on pathogen type, the native bacterial and viral antigens market is segmented into inactivated pathogen and purified pathogen. The inactivated pathogen segment held a larger share of the market in 2019, and it is estimated to register a higher CAGR during the forecast period.

Application-Based Insights

Based on application, the native bacterial and viral antigens market is segmented into ELISA, immunoassay, SDS-PAGE, hemagglutination, and agglutination tests. The ELISA segment held the largest share of the market in 2019 and is estimated to register the highest CAGR during 2020–2027.

End User-Based Insights

Based on end user, the native bacterial and viral antigens market is segmented into diagnostic laboratories and centers and academic and research institutes. The diagnostic laboratories and centers segment held the largest share of the market in 2019, and it is estimated to register the highest CAGR from 2020 to 2027.

Product launches and approvalsare the commonly adopted strategies by companies to expand their global footprintsand product portfolios; these strategies help them meet the growing consumer demand. Collaboration is one of the major strategies adopted by the companies operating in the native bacterial and viral antigens market to enlarge customer base worldwide, which also permits them to maintain their brand name globally.

Native Bacterial and Viral Antigens Market Regional Insights

The regional trends and factors influencing the Native Bacterial and Viral Antigens Market throughout the forecast period have been thoroughly explained by the analysts at Insight Partners. This section also discusses Native Bacterial and Viral Antigens Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.

Native Bacterial and Viral Antigens Market Report Scope

Native Bacterial and Viral Antigens Market Players Density: Understanding Its Impact on Business Dynamics

The Native Bacterial and Viral Antigens Market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.

Market players density refers to the distribution of firms or companies operating within a particular market or industry. It indicates how many competitors (market players) are present in a given market space relative to its size or total market value.

Major Companies operating in the Native Bacterial and Viral Antigens Market are:

1. BIO-RAD LABORATORIES INC.
2. Microbix Biosystems
3. SERION Immunologics
4. Aalto Bio Reagents Ltd
5. Enzo Life Sciences Inc.

Disclaimer: The companies listed above are not ranked in any particular order.

Native Bacterial and Viral Antigens Market – byProduct Type

• Chlamydia Antigens 

• Adenovirus Antigens
• Borrelia Antigens
• Chikungunya Virus Antigens
• Clostridium Antigens
• Dengue Virus Antigens

Native Bacterial and Viral Antigens Market – by Pathogen Type

• Inactivated Pathogen
• Purified Pathogen

Native Bacterial and Viral Antigens Market – by Application

• ELISA
• Immunoassay
• SDS-PAGE
• Hemagglutination
• Agglutination Test

Native Bacterial and Viral Antigens Market – by EndUser

• Diagnostic Laboratories and Centers
• Academic and Research Institutes

Native Bacterial and Viral Antigens Market– by Geography

• North America

  • US
  • Canada
  • Mexico

• Europe

  • France
  • Germany
  • Italy
  • UK
  • Spain
  • Rest of Europe

• Asia Pacific (APAC)

  • China
  • India
  • South Korea
  • Japan
  • Australia
  • Rest of Asia Pacific

• Middle East and Africa (MEA)

  • South Africa
  • Saudi Arabia
  • UAE
  • Rest of Middle East and Africa

• South and Central America

  • Brazil
  • Argentina
  • Rest of South America

Company Profiles

• BIO-RAD LABORATORIES INC.
• Microbix Biosystems
• SERION Immunologics
• Aalto Bio Reagents Ltd
• Enzo Life Sciences Inc.
• Jena Bioscience GmbH
• ROSS SOUTHERN LABORATORIES
• The Native Antigen Company
• Creative Diagnostics
• TRINA BIOREACTIVES AG