Next-Generation Antibody Market Size & Growth | Report by 2028

Next-Generation Antibody Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Therapeutic Area (Oncology and Autoimmune or Inflammatory) and Technology (Antibody-Drug Conjugates, Bispecific Antibodies, Fc Engineered Antibodies, Antibody Fragments and Antibody-Like Proteins, and Biosimilar Antibody Products)

Publication Month : Jan 2022

  • Report Code : TIPRE00006412
  • Category : Medical Device
  • Status : Published
  • No. of Pages : 181
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The next-generation antibody market is expected to reach US$ 12,050.13 million by 2028 from US$ 5,468.41 million in 2021; it is estimated to grow at a CAGR of 11.9% from 2021 to 2028.

Next-generation antibodies are designed to be more specific and often more potent than traditional monoclonal antibodies. Next-generation antibody strategies are required to engineer a useful therapeutic combining antibody, payload, linker, and conjugation method while ensuring stability, targeted delivery, and limited off-target effects.

The report offers insights and in-depth analysis of the next-generation antibody market, emphasizing various parameters such as market trends, technological advancements, market dynamics, and competitive landscape analysis of leading market players worldwide. It also includes the impact of the COVID-19 pandemic on the market across all the regions. The pandemic has disrupted the socioeconomic conditions of various countries across the world. Presently, the US is the world's worst-affected country due to the COVID-19 outbreak with the highest number of confirmed cases and deaths across the world, as per the recent WHO statistics. The high number of COVID-19 positive cases has negatively impacted the global economies. There has been a decline in overall business activities and the growth of various industries operating worldwide.


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Next-Generation Antibody Market: Strategic Insights

next-generation-antibody-market
Market Size Value inUS$ 5,468.41 million in 2021
Market Size Value byUS$ 12,050.13 million by 2028
Growth rateCAGR of 11.9% from 2021 to 2028
Forecast Period2021-2028
Base Year2021
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Akshay

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The COVID-19 outbreak has put an immense burden on healthcare infrastructure in the US, Canada, and Mexico. In addition, most pharmaceutical and biotechnological companies and research institutes are engaged in developing COVID-19 vaccines and drugs. Both set pharmaceutical companies and small startups have come forward to advance treatments and vaccines that target the infection created by the novel coronavirus. As a result, vaccine-related research activities in pharmaceutical and biotechnology companies, research centers, and educational research institutes are acknowledged essential and have been primarily unaffected in operations and output. However, due to the rise in research activities, both the accessibility of funding for analysis and the need for antibodies, including next-generation antibodies, are anticipated to grow. In addition, at the lead of the COVID-19 outbreak, many researchers worldwide are involved in the viral examination of SARS-CoV-2, the virus that develops COVID-19. For both vaccines and therapeutics, the antibodies generated are examined for their functional efficiency to counterbalance the target virus. Therefore, the COVID-19 pandemic is expected to positively impact the next-generation antibody market in the coming years.

Based on region, the next-generation antibody market is segmented into North America, Europe, Asia Pacific, the Middle East & Africa, and South and Central America.

Lucrative Regions for Next-Generation Antibody Market

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Market Insights

Growing Demand for Next-Generation Antibody Therapeutics to Drive Next-Generation Antibody Market

Rising developments in biotechnology have led to an increasing acceptance for next-generation antibodies therapeutics, which is driving its use in autoimmune, inflammatory, and chronic diseases treatment. Next-generation antibody treatments have resulted from the application of sophisticated technologies in antibody therapeutics, such as antibody–drug conjugates (ADCs), glycoengineered antibodies, and specific antibodies (BsAbs). Therefore, applications of next-generation antibodies are being widely studied to treat various chronic diseases such as cancer, HIV, infectious diseases etc. The rising demand for these antibodies have resulted in the rapid increase in the approval of ADCs and other next-generation antibodies therapeutics. For instance, in May 2020, Takeda Pharmaceutical Company Limited announced the FDA approval of ALUNBRIG (brigatinib) for adult patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer (NSCLC) as detected by an FDA-approved test. ALUNBRIG's current indication has been expanded to encompass the first-line setting with its approval. ALUNBRIG is a next-generation tyrosine kinase inhibitor (TKI) designed to target ALK molecular abnormalities. Similarly, in 2019, Genentech announced FDA accelerated approval of Polatuzumab vedotin-piiq, a CD79b-directed antibody-drug conjugate indicated in combination with bendamustine and a rituximab product for adult patients with relapsed or refractory diffuse large B-cell lymphoma.

Therefore, the next-generation antibody market is anticipated to grow rapidly during the forecast period due to the rising clinical trials approvals and high adoption of next-generation antibodies therapeutics for the treatment of various diseases.

Therapeutic Area-Based Insights

Based on therapeutic area, the next-generation antibody market is bifurcated into oncology and autoimmune or inflammatory. The oncology segment accounted for a larger share of the market.  

Next-Generation Antibody Market, by Therapeutic Area, 2021 and 2028

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Technology-Based Insights

Based on technology, the next-generation antibody market is segmented into antibody-drug conjugates, bispecific antibodies, Fc engineered antibodies, antibody fragments & antibody-like proteins, and biosimilar antibody products. The antibody-drug conjugates segment held the largest share of the market in 2021, and the same segment is estimated to register the highest CAGR of 12.1% in the market during the forecast period.

The next-generation antibody market players adopt various organic strategies, such as product launch and expansion, to expand their footprint and product portfolio worldwide and meet the growing demand.

Company Profiles

  • F. HOFFMANN-LA ROCHE LTD.      
  • Kyowa Kirin Co., Ltd.                 
  • Seagen Inc.                             
  • ImmunoGen, Inc.                     
  • Takeda Pharmaceutical Company Limited  
  • Amgen Inc.                             
  • Pfizer Inc.                               
  • Catalent Inc                             
  • AstraZeneca                            
  • Xencor
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Therapeutic Area, and Technology

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions


Which is the potential market for next-generation antibodies in terms of the region?

The Asia Pacific registered as the fastest-growing region in the global next-generation antibody market. The market in this region is expected to grow significantly in countries such as China, Japan, and India. The market is driven by growing investments from international players in China and India, improving government support in countries such as China, expanding R&D, and advancing healthcare infrastructure. Therefore, the region holds huge potential for the next-generation antibody market players to grow during the forecast period.

What are the drivers and restraints for the next-generation antibody market?

The growth of the market is attributed to the increasing prevalence of cancer and growing demand for next-generation antibody therapeutics drives the market growth. However, the complications associated with the manufacturing and approvals hampers the market growth.

Who are the key players in the next-generation antibody market?

The disposable pipettes tips market majorly consists of players like F. HOFFMANN-LA ROCHE LTD., Kyowa Kirin Co., Ltd., Seagen Inc., ImmunoGen, Inc., Takeda Pharmaceutical Company Limited, Amgen Inc., Pfizer Inc., Catalent Inc, AstraZeneca, and Xencor among others.

Which is the therapeutic area where the next-generation antibodies are often used?

The next-generation antibodies are used in the therapeutic areas- oncology and oncology, and autoimmune or inflammatory. Mostly, the next-generation antibodies are used in the oncology field. The oncology segment is likely to hold the largest share of the market in 2021. Moreover, the oncology segment is anticipated to register the highest CAGR in the market during the forecast period, due to the vast usage of next-generation antibodies for cancers, high volume consumption, and product innovation for this field

What is the market CAGR value of the next-generation antibody market during the forecast period?

The global next-generation antibody market is expected to reach US$ 5,428.41 million in 2028 from US$ 12,050.13 million in 2021. The market is estimated to grow with a CAGR of 11.9% from 2021-2028.

The List of Companies - Next-generation Antibody Market

  1. F. HOFFMANN-LA ROCHE LTD.      
  2. Kyowa Kirin Co., Ltd.         
  3. Seagen Inc.           
  4. ImmunoGen, Inc.              
  5. Takeda Pharmaceutical Company Limited               
  6. Amgen Inc.           
  7. Pfizer Inc.              
  8. Catalent Inc          
  9. AstraZeneca         
  10. Xencor

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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