Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Report 2025-2031: Key Players & Insights

The Nonsteroidal Anti-inflammatory Drugs (NSAID) market size is projected to reach US$ 38.38 billion by 2031 from US$ 24.82 billion in 2024. The market is expected to register a CAGR of 6.5% during 2025–2031. 

Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Analysis

The surging prevalence of chronic pain disorders and inflammatory conditions such as arthritis and headaches, and the growing adoption of non-opioid NSAIDs, are propelling the growth of the nonsteroidal anti-inflammatory drugs (NSAID) market. The introduction of NSAIDs offers an efficient approach for the treatment of pain and inflammation. In response to the growing burden of chronic pain, pharmaceutical companies are introducing new NSAID formulations to meet patient needs.

The increasing strategic initiatives by manufacturers of NSAIDs present a significant market opportunity. They are a major factor contributing to the growth of nonsteroidal anti-inflammatory drugs (NSAIDs).

Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Overview

The global market for Nonsteroidal Anti-Inflammatory Drugs is expected to grow steadily in the coming years. An increase in chronic pain, inflammatory disorders, and an aging population fuels this growth.

NSAIDs can be classified by their chemical structure and their selectivity for COX enzymes. Some are nonselective, affecting both COX-1 and COX-2, while others are selective for COX-2. These drugs are a group of medications that reduce pain, fever, and inflammation. They commonly treat conditions such as arthritis, muscle pain, and menstrual cramps.

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Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market: Strategic Insights

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Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Drivers and Opportunities

Market Drivers:

• Expanding Preference for NSAIDs as Non-Opioid Pain Management:

  NSAIDs are increasingly recognized for effectively alleviating pain while reducing the risk of dependency and side effects commonly linked to opioids. As a result, more patients and providers are turning to these medications to address pain more safely and sustainably.

• Increasing Prevalence Of Chronic and Inflammatory Diseases:

  The introduction of NSAIDs offers an efficient approach for the treatment of pain and inflammation-causing disorders such as headaches, osteoarthritis, muscle and joint injuries, and various neuropathies.

• Rising Aging Population:

  Aging populations in countries such as Japan, China, and South Korea contribute further, as elderly individuals are more prone to these ailments.

Market Opportunities:

• Expansion in Emerging Economies:

  Several countries in Asia Pacific, Latin America, and Africa offer growth opportunities in the nonsteroidal anti-inflammatory drugs (NSAID) market due to the increasing number of chronic infections and adoption of non-opioid pain management.

• Rising Strategic Initiatives:

  Increasing organic and inorganic initiatives, such as new product launches and geographical expansion by market players, offer lucrative opportunities for market size expansion.

Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Report Segmentation Analysis

The nonsteroidal anti-inflammatory drugs (NSAID) market is divided into different segments to give a clearer view of how it works, its growth potential, and the latest trends. Below is the standard segmentation approach used in most industry reports:

By Drug Class:

• Nonselective NSAIDs:

  Nonselective COX-2 inhibitors, including ibuprofen and naproxen, effectively reduce pain and inflammation by inhibiting both COX-1 and COX-2 enzymes. These drugs are increasingly in demand due to their broad-spectrum anti-inflammatory and analgesic effects.

• COX-2 Selective NSAIDs:

  Selective COX-2 inhibitors, such as celecoxib (Celebrex) and etoricoxib, are designed to specifically block the enzyme cyclooxygenase-2 (COX-2), which is primarily responsible for producing prostaglandins that cause pain, inflammation, and fever during tissue injury.

By Route Of Administration:

• Oral:

  Oral NSAIDs can offer consistent systemic effects necessary for addressing widespread inflammation. Their efficacy, ease of use, and broad availability contribute to their increasing popularity.

• Injectable:

  Injectable NSAIDs allow for shorter hospital stays and improved patient satisfaction by providing effective pain control early after surgery or trauma.

• Topical:

  Patients and clinicians prefer topical NSAIDs to reduce systemic exposure and adverse events. Regulatory approvals of topical diclofenac formulations—such as gel 1%, patch 1.3%, and solution 1.5%—support this trend.

By Route Of Administration:

• Arthritis
• Migraine
• Ophthalmic Diseases
• Others

By Distribution Channel:

• Hospital Pharmacies
• Retail Pharmacies
• Online Channels

By Geography:

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa

The nonsteroidal anti-inflammatory drugs (NSAID) market in North America is expected to hold a significant share of the market.

Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market Regional Insights

The regional trends and factors influencing the Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market throughout the forecast period have been thoroughly explained by the analysts at The Insight Partners. This section also discusses Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.

Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market Report Scope

Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market Players Density: Understanding Its Impact on Business Dynamics

The Nonsteroidal Anti-Inflammatory Drugs (NSAID) Market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.

Asia Pacific is expected to grow the fastest in the next few years. Emerging economies such as Latin America, the Middle East, and Africa also have many untapped opportunities for nonsteroidal anti-inflammatory drug providers to expand.

The nonsteroidal anti-inflammatory drugs (NSAID) market grows differently in each region. This is because of factors including surging prevalence of inflammatory diseases, a growing aging population, and increasing business development initiatives by the market players. Below is a summary of market share and trends by region:

1. North America

• Market Share:

  Holds a significant portion of the global market

• Key Drivers:

  • Rise in musculoskeletal disorders, including arthritis.
  • Increased awareness of the adverse effects of opioid painkillers

• Trends:

  Shift toward safer NSAID formulations with better gastrointestinal (GI) and cardiovascular profiles.

2. Europe

• Market Share:

  Substantial share due to the adoption of OTC NSAIDs.

• Key Drivers:

  • Government support and favorable reimbursement policies.
  • Growing awareness of migraines and other pain conditions.

• Trends:

  Technological advancements in drug delivery systems.

3. Asia Pacific

• Market Share:

  Fastest-growing region with a rising market share every year

• Key Drivers:

  • Increasing aging population.
  • Growing demand for OTC NSAIDs
  • Increasing disposable income

• Trends:

  Rise in medical tourism

4. South and Central America

• Market Share:

  Growing market with steady progress

• Key Drivers:

  • Expanding access to healthcare services, particularly in urban areas
  • Availability of essential drugs at subsidized rates
•  

  Trends:

  Rise in medical tourism

5. Middle East and Africa

• Market Share:

  Although small, it is growing quickly

• Key Drivers:

  • Expanding Healthcare infrastructure
  • Rising awareness about hygiene and infection control in healthcare settings

• Trends:

  Government initiatives supporting healthcare infrastructure.

Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Players Density: Understanding Its Impact on Business Dynamics

High Market Density and Competition

1. Competition is strong due to the presence of established players such as Boehringer Ingelheim International GmbH, Hikma, and Novartis AG. Regional and niche providers like Pfizer (Asia Pacific) and Dr. Reddy's Laboratories Ltd (Asia Pacific) also add to the competitive landscape across different regions.

This high level of competition urges companies to stand out by offering:

• Advanced Products
• Value-added services like customization and sustainable solutions
• Competitive pricing models
• Compliance with regulatory guidelines

Opportunities and Strategic Moves

• Focusing on specialized gloves for sectors such as medical, food processing, industrial, and laboratory, featuring antimicrobial coatings and smart sensors for health monitoring.
• Companies are moving towards biodegradable and recyclable glove products to address regulatory and consumer concerns about plastic waste and environmental impact.
• Focusing on direct-to-consumer channels and enhancing the use of e-commerce platforms to reach a wider range of customer segments.

Major Companies operating in the Nonsteroidal Anti-inflammatory Drugs (NSAID) Market are:

1. Pfizer
2. Bayer AG
3. Glenmark Pharmaceuticals Ltd.
4. Dr. Reddy's Laboratories Ltd
5. Boehringer Ingelheim International GmbH
6. Haleon plc
7. Sun Pharmaceutical Industries Ltd
8. Novartis AG
9. Hikma Pharmaceuticals
10. Viatris Inc. 

Disclaimer: The companies listed above are not ranked in any particular order.

Other companies analysed during the course of research:

• Teva Pharmaceutical Industries
• Mylan
• Aurobindo Pharma
• Actavis
• Wuxi AppTec
• Zhejiang NHU
• Johnson & Johnson (McNeil)
• Sanofi
• Reckitt Benckiser Group
• Horizon Therapeutics
• Assertio Holdings
• Perrigo Company
• AbbVie
• Endo International
• Orion Corporation
• Strides Pharma Science Limited

Nonsteroidal Anti-inflammatory Drugs (NSAID) Market News and Recent Developments

• Boehringer Ingelheim BioXcellence is expanding its service portfolio in China

  Boehringer Ingelheim's biopharmaceutical facility in Shanghai, China, meets the conditions required to participate in a regulatory reform promoting the segmented manufacturing of biological products by the local authorities.

• Hikma Pharmaceuticals PLC (Hikma) launched Indomethacin suppositories in the US.

  Hikma Pharmaceuticals PLC (Hikma), the multinational pharmaceutical company, launched Indomethacin Suppositories in the US in a 50mg dose. This product has been approved for marketing in the United States by the US FDA.

Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Report Coverage and Deliverables

The "Nonsteroidal Anti-inflammatory Drugs (NSAID) Market Size and Forecast (2021–2031)" report provides a detailed analysis of the market covering below areas:

• Nonsteroidal Anti-inflammatory Drugs (NSAID) Market size and forecast at global, regional, and country levels for all the key market segments covered under the scope
• Nonsteroidal Anti-inflammatory Drugs (NSAID) Market trends, as well as market dynamics such as drivers, restraints, and key opportunities
• Detailed PEST and SWOT analysis
• Nonsteroidal Anti-inflammatory Drugs (NSAID) Market analysis covering key market trends, global and regional framework, major players, regulations, and recent market developments
• Industry landscape and competition analysis covering market concentration, heat map analysis, prominent players, and recent developments for the Nonsteroidal Anti-inflammatory Drugs (NSAID) Market
• Detailed company profiles