Protein Expression Market Growth and Analysis by 2028

Historic Data: 2019-2020   |   Base Year: 2021   |   Forecast Period: 2022-2028

Protein Expression Market Forecast to 2028 - Covid-19 Impact and Global Analysis - By Product (Competent Cells, Expression Vectors, Reagents and Instruments); Services (Antibody Development & Production, Protein Expression & Production, Hybridoma One-Stop Services, Stable Cell Line Development and Bioanalytical Assay Services); Application (Research, Therapeutic, Industrial); End User (Pharmaceutical and Biotechnology Companies, Contract Research Organizations, Academic Research Institutes, Others) and Geography

  • Report Date : Aug 2021
  • Report Code : TIPHE100001247
  • Category : Life Sciences
  • Status : Published
  • Available Report Formats : pdf-format excel-format
  • No. of Pages : 197

The protein expression market is expected to reach US$ 4,000.67 million in 2028 from US$ 2,221.73 million in 2021. The market is estimated to grow with a CAGR of 8.8% from 2021-2028.

The scope of the Protein Expression market includes product type, services, application, end user, and region. Based on region, the Protein Expression market is segmented into North America, Europe, Asia Pacific, Middle East & Africa, and South and Central America. The report offers insights and in-depth analysis of the Protein Expression market emphasizing on various parameters such as market trends, technological advancements, market dynamics, and competitive landscape analysis of leading market players across the world. It also includes COVID–19 impact analysis across the regions.

Market Insights

Increasing Applications of Protein Expression

Protein expression, an integral tool in biological research, is increasingly vital as a pharmaceutical production mechanism for biological therapeutics. The combination of old technologies, such as artificial enzymes, and new next-generation expression systems is revitalizing protein expression protocols. The development of genetic engineering and cloning has opened many possibilities for the expression and isolation of heterologous proteins for research purposes. Considerable advances in technology have enabled the expression and isolation of recombinant proteins on a large scale.

The demand for recombinant proteins for human application is increasing day by day. There is a huge demand for novel and improved bioprocessing strategies that are cost-effective and time-saving. The continuous improvement in biopharmaceutical expression systems has led to the production of quality products. Modern molecular biology techniques are at the forefront of the production of biopharmaceutical proteins using various prokaryote or eukaryote expression systems. Different innovative techniques, such as systems biology, metabolic engineering, and CRISPR/Cas systems, can be applied for strain engineering to improve bioprocess performance and generate biologically active and stable proteins.

Customize This Report To Suit Your Requirement

You will get customization on any report - free of charge - including parts of this report, or country-level analysis, Excel Data pack, as well as avail great offers and discounts for start-ups & universities

Protein Expression Market: Strategic Insights

protein-expression-market
  • Get Top Key Market Trends of this report.
    This FREE sample will include data analysis, ranging from market trends to estimates and forecasts.

The global burden of dengue is rapidly increasing and will continue until the development of an effective vaccine against it. Various vaccine candidates for dengue are at preclinical and clinical trials stages of development based on different approaches. A few vaccines are a tetravalent, live attenuated virus, purified inactivated virus, recombinant proteins subunit, plasmid DNA, and virus-vectored dengue vaccines. Recent progress on recombinant subunit-based dengue vaccine candidates using various approaches, such as fusion with other immunogenic epitopes, use of a novel adjuvant, protein expression in different host systems, designer vaccine, and VLPs development, is opening new avenues for the development of a fully efficacious vaccine against dengue.

Currently, more than 65 million confirmed cases and over 1.5 million deaths are reported. The COVID-19 pandemic has led to significant health, social, and global economic crises. The development of a vaccine for COVID-19 is an effective strategy to control the outbreak. It is required that the vaccine is produced at high speed and is easily scalable. Recombinant protein, viral-vectored or nucleic acid-based (recombinant plasmid DNA and mRNA) vaccines need to be considered to shorten the vaccine production timeframe. The use of protein expression is increasing during vaccine development due to the advantages of recombinant protein, which drives the growth of the protein expression market.  

Product Type-Based Insights

Based on product type, the protein expression market is segmented into instruments, reagents, expression vectors, and competent cells. The reagents segment held the largest share of the market in 2021. Also, the reagents segment is estimated to register the highest CAGR of 9.5% in the market during the forecast period.

Services-Based Insights

Based on services, the protein expression market is segmented into antibody development & production, protein expression & production, hybridoma one-stop services, stable cell line development, bioanalytical assay services. The antibody development & production segment held the largest share of the market in 2021. However, same segment is estimated to register the highest CAGR of 9.7% in the market during the forecast period.

Application-Based Insights

Based on application, the protein expression market is segmented into research, therapeutic, industrial. The therapeutic segment held the largest share of the market in 2021 and same segment is estimated to register the highest CAGR of 9.4% in the market during the forecast period.

End User-Based Insights

 

Based on end user, the protein expression market is segmented into pharmaceutical and biotechnology companies, academic research institutes, and contract research organizations. The pharmaceutical and biotechnology companies segment held the largest share of the market in 2021. Also, the segment is estimated to register the highest CAGR of 5.6% in the market during the forecast period.

Inorganic strategies such as partnerships, and mergers and acquisitions are commonly adopted by companies to cater to changing customer demand and maintain their brand name across the world. Market players operating in the Protein Expression market also adopt organic strategies such as product launch and expansion to outstretch their footprint and product portfolio worldwide as well as to meet the growing demand.

Protein Expression Market Regional Insights

The regional trends and factors influencing the Protein Expression Market throughout the forecast period have been thoroughly explained by the analysts at Insight Partners. This section also discusses Protein Expression Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.

protein-expression-market-global-geography
  • Get the Regional Specific Data for Protein Expression Market

Protein Expression Market Report Scope

Report Attribute Details
Market size in 2021 US$ 2.22 Billion
Market Size by 2028 US$ 4 Billion
Global CAGR (2021 - 2028) 8.8%
Historical Data 2019-2020
Forecast period 2022-2028
Segments Covered By Product
  • Competent Cells
  • Expression Vectors
  • Reagents and Instruments
By Services
  • Antibody Development & Production
  • Protein Expression & Production
  • Hybridoma One-Stop Services
  • Stable Cell Line Development and Bioanalytical Assay Services
By Application
  • Research
  • Therapeutic
  • Industrial
By End User
  • Pharmaceutical and Biotechnology Companies
  • Contract Research Organizations
  • Academic Research Institutes
Regions and Countries Covered North America
  • US
  • Canada
  • Mexico
Europe
  • UK
  • Germany
  • France
  • Russia
  • Italy
  • Rest of Europe
Asia-Pacific
  • China
  • India
  • Japan
  • Australia
  • Rest of Asia-Pacific
South and Central America
  • Brazil
  • Argentina
  • Rest of South and Central America
Middle East and Africa
  • South Africa
  • Saudi Arabia
  • UAE
  • Rest of Middle East and Africa
Market leaders and key company profiles
  • Thermo Fisher Scientific, Inc.
  • GenScript
  • Merck KGaA
  • Agilent Technologies, Inc.
  • Takara Bio Inc.
  • Bio-Rad Laboratories, Inc.
  • QIAGEN
  • New England Biolabs.
  • Promega Corporation

  • Protein Expression Market Players Density: Understanding Its Impact on Business Dynamics

    The Protein Expression Market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.

    Market players density refers to the distribution of firms or companies operating within a particular market or industry. It indicates how many competitors (market players) are present in a given market space relative to its size or total market value.

    Major Companies operating in the Protein Expression Market are:

    1. Thermo Fisher Scientific, Inc.
    2. GenScript
    3. Merck KGaA
    4. Agilent Technologies, Inc.
    5. Takara Bio Inc.

    Disclaimer: The companies listed above are not ranked in any particular order.


    protein-expression-market-cagr

    • Get the Protein Expression Market top key players overview

    By Product Type

    • Competent Cells
    • Expression Vectors
    • Reagents
    • Instruments

    By Services

    • Antibody Development & Production
    • Protein Expression & Production
    • Hybridoma One-Stop Services
    • Stable Cell Line Development
    • Bioanalytical Assay Services

    By Application

    • Research
    • Therapeutic
    • Industrial

    By End User

    • Pharmaceutical and Biotechnology Companies
    • Contract Research Organizations
    • Academic Research Institutes
    • Others

    By Geography

    • North America
      • US
      • Canada
      • Mexico
    • Europe
      • France
      • Germany
      • Italy
      • UK
      • Spain
      • Rest of Europe
    • Asia Pacific (APAC)
      • China
      • India
      • South Korea
      • Japan
      • Australia
      • Rest of APAC
    • Middle East & Africa (MEA)
      • South Africa
      • Saudi Arabia
      • UAE
      • Rest of MEA
    • South and Central America (SCAM)
      • Brazil
      • Argentina
      • Rest of SCAM

    Company Profiles

    • Thermo Fisher Scientific, Inc.
    • GenScript
    • Merck KGaA
    • Agilent Technologies, Inc.
    • Takara Bio Inc.
    • Bio-Rad Laboratories, Inc.
    • QIAGEN
    • New England Biolabs.
    • Promega Corporation
    • Oxford Expression Technologies Ltd

    Frequently Asked Questions

    Which region is projected to be the fastest growing region in the global Protein Expressionmarket?

    Asia Pacific is projected to be the fastest growing region in the global market.

    What is the cost of Protein Expression?

    The costs of the Protein Expression are much higher, and they may cost US$ 300–1500, or more, per type. The cost may also differ from product to product types.

    What will be the CAGR of Protein Expression market?

    The Protein Expression market is anticipated to grow around 8.8% CAGR amid the forecast period 2021-2028.

    What are the driving factors for the Protein Expression market across the globe?

    Driving factors such as an development in the arena of proteomics and biotechnology industry, rising incidences of chronic and autoimmune diseases, rise in the awareness among people regarding protein expression, increasing focus on research and development process, growing usage of protein expression technologies in industrial protein manufacturing organizations, and rise in adoption of protein-based drugs over non-protein-based drugs are the prime growth drivers of protein expression market. In addition, increase in adoption of protein expression in emerging economies such as China, India and others, will create new opportunities for protein expression market. However, higher cost of the research and development, and complex government approval processes are the key restraints for protein expression market.

    What are Protein Expression?

    Protein expression is a process in which proteins are synthesized, modified and regulated. Protein expression involves laboratory techniques & procedures which aid in manufacture of proteins. The technique allows to produce and purify the desired protein, either inside or outside a cell. The proteins synthesized using protein expression technique can be used for industrial processes or to diagnose and to treat diseases. Protein expression provides substrates or enzymes required for further analysis

    Mrinal Kerhalkar
    Mrinal Kerhalkar
    Manager,
    Market Research & Consulting

    Mrinal is a seasoned research analyst with over 8 years of experience in Life Sciences Market Intelligence and Consulting. With a strategic mindset and unwavering commitment to excellence, she has built deep expertise in pharmaceutical forecasting, market opportunity assessment, and developing industry benchmarks. Her work is anchored in delivering actionable insights that empower clients to make informed strategic decisions.

    Mrinal’s core strength lies in translating complex quantitative datasets into meaningful business intelligence. Her analytical acumen is instrumental in shaping go-to-market (GTM) strategies and uncovering growth opportunities across the pharmaceutical and medical device sectors. As a trusted consultant, she consistently focuses on streamlining workflow processes and establishing best practices, thereby driving innovation and operational efficiency for her clients.

    • Historical Analysis (2 Years), Base Year, Forecast (7 Years) with CAGR
    • PEST and SWOT Analysis
    • Market Size Value / Volume - Global, Regional, Country
    • Industry and Competitive Landscape
    • Excel Dataset

    Testimonials

    user

    I wish to appreciate your support and the professionalism you displayed in the course of attending to my request for information regarding to infectious disease IVD market in Nigeria. I appreciate your patience, your guidance, and the fact that you were willing to offer a discount, which eventually made it possible for us to close a deal. I look forward to engaging The Insight Partners in the future, all thanks to the impression you have created in me as a result of this first encounter.

    DR CHIJIOKE ONYIA, MANAGING DIRECTOR, PineCrest Healthcare Ltd.
    user

    The Insight Partners delivered insightful, well-structured market research with strong domain expertise. Their team was professional and responsive throughout. The user-friendly website made accessing industry reports seamless. We highly recommend them for reliable, high-quality research services

    Yukihiko Adachi CEO, Deep Blue, LLC.

    Reason to Buy

    • Informed Decision-Making
    • Understanding Market Dynamics
    • Competitive Analysis
    • Customer Insights
    • Market Forecasts
    • Risk Mitigation
    • Strategic Planning
    • Investment Justification
    • Identifying Emerging Markets
    • Enhancing Marketing Strategies
    • Boosting Operational Efficiency
    • Tracking Industry Innovations
    • Aligning with Regulatory Trends
    Your Key Concerns Addressed - Question & Answer
    Can I view a sample of the report before purchasing?

    Yes! We provide a free sample of the report, which includes Report Scope (Table of Contents), report structure, and selected insights to help you assess the value of the full report. Please click on the "Download Sample" button or contact us to receive your copy.

    Is analyst support included with the purchase?

    Absolutely — analyst assistance is part of the package. You can connect with our analyst post-purchase to clarify report insights, methodology or discuss how the findings apply to your business needs.

    What are the next steps once I place an order?

    Once your order is successfully placed, you will receive a confirmation email along with your invoice.

    • For published reports: You’ll receive access to the report within 4–6 working hours via a secured email sent to your email.
    • For upcoming reports: Your order will be recorded as a pre-booking. Our team will share the estimated release date and keep you informed of any updates. As soon as the report is published, it will be delivered to your registered email.

    Can the report be tailored to suit my specific needs?

    We offer customization options to align the report with your specific objectives. Whether you need deeper insights into a particular region, industry segment, competitor analysis, or data cut, our research team can tailor the report accordingly. Please share your requirements with us, and we’ll be happy to provide a customized proposal or scope.

    In what format is the report delivered?

    The report is available in either PDF format or as an Excel dataset, depending on the license you choose.

    The PDF version provides the full analysis and visuals in a ready-to-read format. The Excel dataset includes all underlying data tables for easy manipulation and further analysis.
    Please review the license options at checkout or contact us to confirm which formats are included with your purchase.

    How secure is the payment process on your platform?

    Our payment process is fully secure and PCI-DSS compliant.

    We use trusted and encrypted payment gateways to ensure that all transactions are protected with industry-standard SSL encryption. Your payment details are never stored on our servers and are handled securely by certified third-party processors.
    You can make your purchase with confidence, knowing your personal and financial information is safe with us.

    Do you provide special pricing for buying multiple reports?

    Yes, we do offer special pricing for bulk purchases.
    If you're interested in purchasing multiple reports, we’re happy to provide a customized bundle offer or volume-based discount tailored to your needs. Please contact our sales team with the list of reports you’re considering, and we’ll share a personalized quote.

    Can I connect with your team to discuss the report before buying?

    Yes, absolutely.
    Our team is available to help you make an informed decision. Whether you have questions about the report’s scope, methodology, customization options, or which license suits you best, we’re here to assist. Please reach out to us at sales@theinsightpartners.com, and one of our representatives will get in touch promptly.

    Will I get a billing invoice upon purchase?

    Yes, a billing invoice will be automatically generated and sent to your registered email upon successful completion of your purchase.
    If you need the invoice in a specific format or require additional details (such as company name, GST, or VAT information), feel free to contact us, and we’ll be happy to assist.

    Is there support available if I can’t access my report?

    Yes, certainly.
    If you encounter any difficulties accessing or receiving your report, our support team is ready to assist you. Simply reach out to us via email or live chat with your order information, and we’ll ensure the issue is resolved quickly so you can access your report without interruption.

    Our Clients

    The List of Companies - Protein Expression Market

    1. Thermo Fisher Scientific, Inc.
    2. GenScript
    3. Merck KGaA
    4. Agilent Technologies, Inc.
    5. Takara Bio Inc.
    6. Bio-Rad Laboratories, Inc.
    7. QIAGEN
    8. New England Biolabs.
    9. Promega Corporation
    10. Oxford Expression Technologies Ltd
    Sales Assistance
    US: +1-646-491-9876
    UK: +44-20-8125-4005
    Email: sales@theinsightpartners.com
    Chat with us
    DUNS Logo
    87-673-9708
    ISO Certified Logo
    ISO 9001:2015
    ISO Certified Logo