Protein Expression Market Growth and Analysis by 2028

The protein expression market is expected to reach US$ 4,000.67 million in 2028 from US$ 2,221.73 million in 2021. The market is estimated to grow with a CAGR of 8.8% from 2021-2028.

The scope of the Protein Expression market includes product type, services, application, end user, and region. Based on region, the Protein Expression market is segmented into North America, Europe, Asia Pacific, Middle East & Africa, and South and Central America. The report offers insights and in-depth analysis of the Protein Expression market emphasizing on various parameters such as market trends, technological advancements, market dynamics, and competitive landscape analysis of leading market players across the world. It also includes COVID–19 impact analysis across the regions.

Market Insights

Increasing Applications of Protein Expression

Protein expression, an integral tool in biological research, is increasingly vital as a pharmaceutical production mechanism for biological therapeutics. The combination of old technologies, such as artificial enzymes, and new next-generation expression systems is revitalizing protein expression protocols. The development of genetic engineering and cloning has opened many possibilities for the expression and isolation of heterologous proteins for research purposes. Considerable advances in technology have enabled the expression and isolation of recombinant proteins on a large scale.

The demand for recombinant proteins for human application is increasing day by day. There is a huge demand for novel and improved bioprocessing strategies that are cost-effective and time-saving. The continuous improvement in biopharmaceutical expression systems has led to the production of quality products. Modern molecular biology techniques are at the forefront of the production of biopharmaceutical proteins using various prokaryote or eukaryote expression systems. Different innovative techniques, such as systems biology, metabolic engineering, and CRISPR/Cas systems, can be applied for strain engineering to improve bioprocess performance and generate biologically active and stable proteins.

Protein Expression Market: Strategic Insights

The global burden of dengue is rapidly increasing and will continue until the development of an effective vaccine against it. Various vaccine candidates for dengue are at preclinical and clinical trials stages of development based on different approaches. A few vaccines are a tetravalent, live attenuated virus, purified inactivated virus, recombinant proteins subunit, plasmid DNA, and virus-vectored dengue vaccines. Recent progress on recombinant subunit-based dengue vaccine candidates using various approaches, such as fusion with other immunogenic epitopes, use of a novel adjuvant, protein expression in different host systems, designer vaccine, and VLPs development, is opening new avenues for the development of a fully efficacious vaccine against dengue.

Currently, more than 65 million confirmed cases and over 1.5 million deaths are reported. The COVID-19 pandemic has led to significant health, social, and global economic crises. The development of a vaccine for COVID-19 is an effective strategy to control the outbreak. It is required that the vaccine is produced at high speed and is easily scalable. Recombinant protein, viral-vectored or nucleic acid-based (recombinant plasmid DNA and mRNA) vaccines need to be considered to shorten the vaccine production timeframe. The use of protein expression is increasing during vaccine development due to the advantages of recombinant protein, which drives the growth of the protein expression market.  

Product Type-Based Insights

Based on product type, the protein expression market is segmented into instruments, reagents, expression vectors, and competent cells. The reagents segment held the largest share of the market in 2021. Also, the reagents segment is estimated to register the highest CAGR of 9.5% in the market during the forecast period.

Services-Based Insights

Based on services, the protein expression market is segmented into antibody development & production, protein expression & production, hybridoma one-stop services, stable cell line development, bioanalytical assay services. The antibody development & production segment held the largest share of the market in 2021. However, same segment is estimated to register the highest CAGR of 9.7% in the market during the forecast period.

Application-Based Insights

End User-Based Insights

Based on end user, the protein expression market is segmented into pharmaceutical and biotechnology companies, academic research institutes, and contract research organizations. The pharmaceutical and biotechnology companies segment held the largest share of the market in 2021. Also, the segment is estimated to register the highest CAGR of 5.6% in the market during the forecast period.

Inorganic strategies such as partnerships, and mergers and acquisitions are commonly adopted by companies to cater to changing customer demand and maintain their brand name across the world. Market players operating in the Protein Expression market also adopt organic strategies such as product launch and expansion to outstretch their footprint and product portfolio worldwide as well as to meet the growing demand.

The regional trends and factors influencing the Protein Expression Market throughout the forecast period have been thoroughly explained by the analysts at The Insight Partners. This section also discusses Protein Expression Market segments and geography across North America, Europe, Asia Pacific, Middle East and Africa, and South and Central America.

Protein Expression Market Report Scope

Protein Expression Market Players Density: Understanding Its Impact on Business Dynamics

The Protein Expression Market is growing rapidly, driven by increasing end-user demand due to factors such as evolving consumer preferences, technological advancements, and greater awareness of the product's benefits. As demand rises, businesses are expanding their offerings, innovating to meet consumer needs, and capitalizing on emerging trends, which further fuels market growth.

By Product Type

• Competent Cells
• Expression Vectors
• Reagents
• Instruments

By Services

• Antibody Development & Production
• Protein Expression & Production
• Hybridoma One-Stop Services
• Stable Cell Line Development
• Bioanalytical Assay Services

By Application

• Research
• Therapeutic
• Industrial

By End User

• Pharmaceutical and Biotechnology Companies
• Contract Research Organizations
• Academic Research Institutes
• Others

By Geography

• North America
  • US
  • Canada
  • Mexico
• Europe
  • France
  • Germany
  • Italy
  • UK
  • Spain
  • Rest of Europe
• Asia Pacific (APAC)
  • China
  • India
  • South Korea
  • Japan
  • Australia
  • Rest of APAC
• Middle East & Africa (MEA)
  • South Africa
  • Saudi Arabia
  • UAE
  • Rest of MEA
• South and Central America (SCAM)
  • Brazil
  • Argentina
  • Rest of SCAM

Company Profiles

• Thermo Fisher Scientific, Inc.
• GenScript
• Merck KGaA
• Agilent Technologies, Inc.
• Takara Bio Inc.
• Bio-Rad Laboratories, Inc.
• QIAGEN
• New England Biolabs.
• Promega Corporation
• Oxford Expression Technologies Ltd