骨科植入物抗菌涂层表面处理市场基于(关键地区、市场参与者、规模和份额)- 到 2031 年的预测

  • Report Code : TIPRE00017477
  • Category : Medical Device
  • Status : Published
  • No. of Pages : 148
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骨科植入物抗菌涂层表面处理市场预计将从2021年的8715万美元增至2028年的17855万美元;预计 2021 年至 2028 年复合年增长率为 10.8%。

细菌感染和感染引起的免疫反应已成为接受骨科植入手术的患者面临的威胁生命的问题。传统生物材料的生物污染会导致细菌侵入受伤部位,导致术后疾病。因此,迫切需要用于骨科植入物的抗感染和免疫逃避涂层。骨科手术医院对螺钉、钢板、钉子和人工关节等骨科植入物的需求不断增加。此外,对在植入物上涂覆抗生物污垢聚合物的需求也在不断增加,以防止生物物质和细菌粘附在表面上。

  

< h3>战略洞察

骨科植入物抗菌涂层表面处理市场按类型、材料类型和地理位置细分。按地域划分,市场大致分为北美、欧洲、亚太地区、中东和中东地区。非洲、南美洲和中美洲。该报告提供了对市场的见解和深入分析,强调市场趋势、技术进步和市场动态等参数,以及对全球领先市场参与者的竞争格局的分析。    

骨科植入物抗菌涂层表面处理市场利润丰厚的区域


市场洞察

植入物相关感染患病率上升,推动骨科植入物抗菌涂层表面处理市场增长

植入物相关感染多种因素造成,包括抗菌预防、细菌载量、微生物和宿主类型、手术程序和技术以及植入物类型。植入物相关感染的日益流行是推动骨科植入物抗菌涂层表面处理市场的重要因素之一。

例如,根据《骨科杂志》报道的研究2018年的手术和研究发现,骨科创伤患者中植入物相关感染的患病率在5%至10%之间。美国每年发现75万至100万例植入物相关感染病例,政府需要花费超过16亿美元来支付因植入物相关感染而产生的超额住院费用。特别是随着骨科植入物的广泛使用,感染植入物的数量不断增加。即使可以通过二次手术成功移除受感染的植入物,肢体的功能和骨折愈合也可能受到限制,这最终可能导致致命的外科手术,例如截肢、关节置换术或关节融合术。因此,植入物相关感染的高流行病学产生了对适当的植入物抗菌涂层处理的需求,这将支持市场的增长。

骨科植入物抗菌涂层表面处理的需求由于假体关节感染(PJI)的发病率很高,这一数字一直在上升。 PJI 是全关节置换术后最严重的并发症。根据《Annals of Joint 2021》发表的一篇文章,仅在美国治疗 PJI 的费用估计就达 16.2 亿美元。 PJI 的发病率因所涉及的关节而异。研究显示,全膝关节置换术、全髋关节置换术和全肩关节置换术的发生率分别为 0.25% 至 2%、0.5% 至 1% 和低于 1%。大约 23% 至 25% 的全膝关节翻修手术和 12% 至 15% 的全髋关节置换手术是针对 PJI 进行的。

此外,根据发布的投资者介绍aap Implantate AG 表示,2020 年,在骨科创伤中,预计高达 30% 的病例可能会导致感染。同样,骨折相关感染(FRI)是骨损伤后的严重并发症,可能构成严重的诊断挑战。根据德国联邦统计局 (Destatis) 的数据,2008 年至 2018 年间,FRI 的患病率从每 10 万居民 8.4 例增加到每 10 万居民 10.7 例,增加了 0.28 例。因此,骨科植入物相关感染患病率的增加将增加骨科植入物抗菌涂层表面处理的需求。

抗菌涂层的技术进步对骨科植入物抗菌涂层表面处理市场的增长做出重大贡献

微生物定植、感染和生物膜形成是种植体使用过程中的严重并发症,也是种植体失败的主要危险因素。为了减少与植入物相关的感染,越来越多地研究抗菌材料并将其应用于植入物表面。抗菌涂层技术似乎是在不影响患者护理的情况下改善医院感染控制的最有效方法。抗菌涂层因其具有防止微生物生长的功能特性,其应用范围相当广泛。许多表面涂层技术正在研究中,从用于医疗器械和外科植入物的药用辅料和抗菌剂,到确保植入物表面消毒的涂层。银以其抗菌和抗菌特性而闻名,因此被广泛应用于抗菌涂层。纳米结构银是最普遍的抗菌剂,可以纳米颗粒、纳米线和纳米层的形式用于骨科植入物。二氧化钛还以其抗菌特性而闻名,该化合物已被证明可以杀死 99.9% 的大肠杆菌菌落。亲水涂层和生物膜抑制表面技术是植入式设备的一些最新技术。

市场参与者越来越关注提供技术先进的医疗产品和具有抗菌涂层的骨科植入物,为预测期内的市场增长做出贡献。例如,Specialty Coating Systems Inc.提供了新的SCS microRESIST抗菌聚对二甲苯技术,该技术可以有效消除涂层医疗器械上的有害微生物。它可以在医疗植入物上涂上具有有效抗菌特性的生物相容性聚对二甲苯涂层。

同样,德国公司 DOT GmbH 提供骨科植入设备物理气相沉积 (PVD) 涂层技术。 PVD 涂层技术涉及使用特殊的氮气电弧蒸发技术将陶瓷硬质材料层涂覆到植入物上。具有这种陶瓷涂层的种植体可以很大程度上防止异物反应,并显着提高种植体表面的生物相容性。除此之外,DOT 还开发了一项名为 BONIT 的创新技术,其中包括将薄的可吸收磷酸钙层应用于骨科植入物的电化学过程。磷酸钙用于医疗涂层技术,因为它们可以确保骨组织的快速生长,并促进植入物与周围组织之间的高强度连接,从而缩短愈合阶段。因此,抗菌涂层的技术进步将推动骨科植入物抗菌涂层表面处理市场的发展。

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类型洞察

基于根据类型,全球骨科植入物抗菌涂层表面处理市场分为被动表面处理/改性(PSM)、主动表面处理/改性(ASM)和围手术期抗菌局部载体或涂层(LCC)。 2020 年,活性表面精加工/改性 (ASM) 领域占据了最大的市场份额。此外,预计同一细分市场在 2021 年至 2028 年期间将实现最高的复合年增长率。 ASM 涉及在骨科植入物表面应用具有药理活性的抗菌剂或化合物,如抗生素、防腐剂、金属离子或有机分子。植入物表面上的此类药理学活性涂层可以将植入物从被动或药理学惰性医疗装置改变为载药医疗装置。 DOT GmbH 和 Harland Medical Systems, Inc. 等公司提供抗菌涂层表面处理,预计将在预测期内推动市场发展。

材料类型洞察

根据材料类型,骨科植入物抗菌涂层表面处理市场为分为金属涂层和非金属涂层。金属涂层细分市场将在 2021 年占据更大的市场份额。此外,由于低剂量水平下的高功效且不产生抗菌耐药性,预计该细分市场将在骨科植入物抗菌涂层表面处理市场中占据重要市场份额。金属基抗菌涂层可以为骨科植入物相关感染提供可持续的解决方案,预计将推动该领域的发展。

骨科植入物抗菌涂层表面处理市场(按类型) – 2021年和2028年

产品上市和并购是全球骨科植入物抗菌涂层表面处理市场参与者高度采用的策略。以下列出了近期的一些关键市场动态:

2021 年 9 月,aap Implantate AG 宣布将三颗涂有该公司创新抗菌银技术的植入物植入患者体内,以检查愈合过程。 aap 解决了创伤学中最大且未充分解决的挑战之一,即手术部位感染 (SSI),因为所有三项手术都有良好的愈合过程,并且没有记录感染迹象。总体结果对 aap 计划于 2021 年第四季度在德国启动以获得 CE 批准的人体临床研究是一个积极的迹象。


2020 年 3 月,Covalon Technologies Ltd. 推出了其突破性抗菌技术称为 CovaGuard,旨在杀死 COVID-19 病毒(或“SARS-CoV-2”)和其他病毒、细菌和病原体,并通过长时间捕获和灭活微生物来提供持续保护。 CovaGuard 可以安全地应用于皮肤和防护性医疗设备上。

由于 COVID-19 大流行,医疗保健系统负担过重,向所有患者提供医疗护理已变得困难世界范围内的挑战。随着 COVID-19 大流行的持续蔓延,医疗器械公司在管理运营方面遇到了困难。许多提供骨科植入物抗菌涂层表面处理产品的公司都在美国开展业务,他们的业务受到了 COVID-19 大流行的负面影响。这种流行病扰乱了产品分销,并导致公司设施暂时关闭。例如,根据 2020 年 5 月发表的《英国外科杂志》,骨科手术受到的影响最大,全球有 630 万例手术因疫情而取消。此外,为减少医院和重症监护病房手术室中对COVID-19的接触而取消的择期手术阻碍了骨科植入物抗菌涂层表面处理市场的增长。然而,到 2021 年,随着新的 COVID-19 病例数量下降以及情况正在复苏,预计市场在未来几天将会增长。

骨科植入物抗菌涂层表面处理——市场细分

全球骨科植入物抗菌涂层表面处理市场按类型、材料类型和地理位置进行细分。就产品而言,市场分为被动表面处理/改性(PSM)、主动表面处理/改性(ASM)和围手术期抗菌局部载体或涂层(LCC)。根据材料类型,骨科植入物抗菌涂层表面处理市场分为金属涂层和非金属涂层。从地域来看,市场大致分为北美、欧洲、亚太地区、中东和中东地区。非洲、南美洲和中美洲。

公司简介

  • DOT GmbH
  • Covalon Technologies Ltd.
  • Sciessent LLC
  • Harland Medical Systems, Inc.
  • Isoflux, Inc.
  • Allvivo Vascular, Inc.
  • aap Implantate AG
  • 巴斯夫SE
  • Agienic Inc.
  • ARAN BIOMEDICAL
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is orthopedic implant antibacterial coatings surface treatment?

Among patients undergoing orthopedic implant surgery, bacterial infection and infection-induced immune responses have become a life-threatening concern. Biocontamination of conventional biomaterials causes bacterial invasion in injured areas, resulting in postoperative illness. As a result, anti-infection and immune-evasive coatings for orthopedic implants are desperately needed. Orthopedic implants such as screws, plates, nails, and artificial joints have grown in great demand by hospitals for orthopedic surgery. Coating the implants with an anti-biofouling polymer, which prevents bio substances and bacteria from adhering onto the surface, is in demand.

What are the driving factors for the orthopedic implant antibacterial coatings surface treatment market across the globe?

Key factors driving the growth of the market are rise in prevalence of implant-associated infections and rise in prevalence of implant-associated infections drive the market growth. However, high cost of implants with antimicrobial coating hampers the market growth.

Which are the key players in the orthopedic implant antibacterial coatings surface treatment market?

Key players in the market are DOT GmbH, Covalon Technologies Ltd., Sciessent LLC, Harland Medical Systems, Inc., Isoflux, Inc., Allvivo Vascular, Inc., aap Implantate AG, BASF SE, Agienic Inc., ARAN BIOMEDICAL among others.

What are the key trends in the orthopedic implant antibacterial coatings surface treatment market?

Increasing number of product launches and strategic initiatives taken by market players is likely to act as trend the market growth in the comping years.

Which is the most influencing segment growing in the orthopedic implant antibacterial coatings surface treatment market report?

Active Surface Finishing/Modifications (ASM) segment growing in the orthopedic implant antibacterial coatings surface treatment market.

What are the opportunities for new orthopedic implant antibacterial coatings surface treatment market entrants?

High market potential in developing economies is likely to fuel the market growth in the comping years.

Which region is lucrative for the orthopedic implant antibacterial coatings surface treatment market?

Asia-Pacific is the lucrative for the orthopedic implant antibacterial coatings surface treatment market.

The List of Companies - Orthopedic Implant Antibacterial Coatings Surface Treatment Market

  1. DOT GmbH
  2. Covalon Technologies Ltd.
  3. Sciessent LLC
  4. Harland Medical Systems, Inc.
  5. Isoflux, Inc.
  6. Allvivo Vascular, Inc.
  7. aap Implantate AG
  8. BASF SE
  9. Agienic Inc.
  10. ARAN BIOMEDICAL

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