制药 ADMET 测试市场基于(关键地区、市场参与者、规模和份额)- 到 2031 年的预测

  • Report Code : TIPRE00029509
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 186
Buy Now

制药 ADMET 测试市场预计将从 2021 年的 67.8306 亿美元增长到 2028 年的 135.7862 亿美元;预计 2022 年至 2028 年复合年增长率为 10.5%。

产品批准和发布数量的增加推动了市场增长。制药 ADMET 测试市场由主要竞争者组成,他们采取各种策略,包括产品发布、地域扩张和技术进步。以下列出了市场的一些最新动态:

  • 2021 年 12 月,Discovery Life Sciences 宣布收购 In Vitro ADMET Laboratories (IVAL),以利用全球最大的肝细胞库存和世界著名的科学领袖。马里兰州 IVAL 提供生理学准确的体外实验系统,以提高制药行业毒理学、药理学和药物代谢测试的有效性。
  • 2022 年 4 月,Discovery Life Sciences 成立,这是一家采用生物样本和生物标志物的公司专家宣布收购康宁公司生命科学部门的 Gentest 业务部门。 Gentest 将并入 Discovery Life Sciences 最近收购的 In Vitro ADMET Laboratories, LLC (IVAL)。这将使 Discovery 成为制药和生命科学行业体外药物试验系统的重要提供商。
  • 2021 年 10 月,专门从事分子诊断的公司 Genetic Analysis AS (GA) 宣布了一项服务协议与 Eurofins ADME BIOANALYSES 合作,这是一家合同研究组织 (CRO),为制药行业提供药代动力学、药效学和药物代谢领域的一系列服务。

战略见解

市场参与者积极参与产品创新和开发,加上产品批准量的增加,推动了制药 ADMET 测试市场的增长。此外,随着先进技术的出现,市场在预测期内将呈指数级增长。

ADMET 测试研究的高成本阻碍了制药 ADMET 测试的增长市场。根据国会预算办公室 2021 年《制药行业研发》报告,开发一种新药的预计成本可能从不到 10 亿美元到超过 20 亿美元不等,包括资本支出和治疗费用(适用于服用未上市药物的患者)。 2019 年,制药行业投入了 830 亿美元用于研发支出。这些支出包括发现和测试新药、开发渐进式创新(如产品扩展)以及用于安全监测或营销目的的临床测试所产生的成本。这一金额约为 20 世纪 80 年代该行业每年支出的 10 倍。由于发现和开发新药的不可预测性和高昂成本,经过临床试验的药物中只有约 12% 最终获得 FDA 批准上市。这些因素阻碍了全球药品 ADMET 测试市场的增长。

区域概览

亚太地区的药品 ADMET 测试复合年增长率最高市场。对毒理学测试产品和精准药物的高需求、药物发现的增加以及主要市场参与者对研发投资的增加是推动亚太市场增长的因素之一。中国的药品 ADMET 测试市场正在扩大,因为该国患有慢性疾病的人口不断增加,导致对个性化医疗的需求。在促进药物体外 ADMET 测试的机构和组织的支持下,中国的药物发现正在蓬勃发展。例如,体外科学研究所(IIVS)与国际政府合作,帮助他们实施非动物测试方法来监管产品和成分。 2019年4月,IIVS认可中国国家药品监督管理局(NMPA)接受化妆品监管的某些非动物(替代)测试方法。

此外,中国制药 ADMET 测试市场的主要参与者正在遵循有机和无机策略,以扩大其在亚太地区的产品组合和业务。例如,2022年6月,药明康德和Wugen Inc.宣布合作生产Wugen的WU-NK-101,这是一种利用记忆自然杀伤(NK)细胞的力量来治疗癌症的新型免疫疗法。根据合作伙伴关系,药明康德同意为 WU-NK-101 提供制造和测试服务,以便为癌症患者提供创新的细胞治疗产品。

由于对药物安全数据的日益重视、对健康经济学和结果研究的新需求以及向个性化医疗和孤儿药开发的转变,韩国的药物 ADMET 检测市场正在逐渐增长。根据全球和区域供应商的可用性、患者群体以及该国当前的监管情况,韩国被认为是最具吸引力的早期阶段目的地。相对于亚洲其他地区,甚至相对于世界其他地区,韩国对 I-IIa 期研究的兴趣和增长与以下因素直接相关:

  • 韩国政府发展生物技术产业
  • 对早期临床研究感兴趣的受过高等教育的医疗和科研人员
  • 接触患者并注重质量
  • 永远-扩大 IT 基础设施。

上述因素正在推动韩国多家 CRO 的扩张。此外,韩国还宣布启动一项五年计划,以推进临床试验并提升该国作为世界研究目的地的地位。 2019年,Novotech公司宣布与韩国两家主要医院建立合作伙伴关系,负责加强Novotech在该国的临床服务能力。预计这些因素将在预测期内推动亚太地区制药 ADMET 测试市场的增长。

全球制药 ADMET 测试市场的利润丰厚的区域

应用洞察

根据应用,全球制药ADMET测试市场分为全身毒性、肾毒性、肝毒性、神经毒性等。据估计,在预测期内,系统毒性部分将占据最大的市场份额。进行药物 ADMET 测试是为了识别或发现药物分子对体内器官的毒性作用。如果药物分子有毒,则可能引起全身毒性或器官毒性。全身毒性影响整个身体或许多器官,而不是特定部位。 ADMET 测试可用于执行不同的化学、药理学和基因测试,以支持整体药物发现活动,包括药物试验、药物设计和其他药物相互作用。此外,有多种药物类别和药物分子会引起全身毒性。局麻药全身毒性(LAST)是通过多种途径给予局麻药后可能发生的危及生命的不良事件。局部麻醉技术在各种医疗保健环境中的使用越来越多,使得对 LAST 的当代理解具有高度相关性。此外,制药 ADMET 测试对于识别分子毒性并在临床前药物开发阶段解决它发挥着关键作用。 2022 年 2 月在施普林格自然杂志上发表的一项题为“预测急性全身毒性的计算机模型”的研究表明,揭示了基于结构的计算模型的使用,该模型在评估急性全身毒性方面可能有用。

肝毒性部分预计在预测期间将出现最高的复合年增长率时期。肝毒性是指药物对肝脏造成的损伤或损伤。这是一种已知的严重药物不良反应。此外,药物引起的肝毒性是药物开发过程中磨损的主要原因。与传统的 2D 单层模型相比,体外三维 (3D) 细胞培养可以更好地再现复杂的体内微环境。因此,使用这种先进的模型来研究肝毒性预计将在 2021 年至 2028 年推动该细分市场的制药 ADMET 测试市场增长。

全球制药 ADMET 测试市场,按应用划分 – 2021 年和 2028 年

在制药 ADMET 测试市场运营的公司采用产品创新战略来满足世界各地不断变化的客户需求,这也使他们能够在市场。

全球制药 ADMET 测试市场 –细分

制药 ADMET 测试市场根据测试类型、技术、应用和地理位置进行细分。根据测试类型,市场分为体内 ADMET 测试、体外 ADMET 测试和计算机 ADMET 测试。根据技术,市场分为细胞培养、高通量、分子成像和组学技术。根据应用,全球药品 ADMET 测试市场分为全身毒性、肾毒性、肝毒性、神经毒性等。按地理位置划分,市场分为北美(美国、加拿大和墨西哥)、欧洲(英国、德国、法国、意大利、西班牙和欧洲其他地区)、亚太地区(中国、日本、印度、澳大利亚) 、韩国和亚太地区其他地区)、中东和美国非洲(阿联酋、沙特阿拉伯、南非以及中东和非洲其他地区)以及南美和非洲中美洲(巴西、阿根廷以及南美洲和中美洲其他地区)。

公司简介

  • CMIC Holdings Co. ,有限公司
  • 查尔斯河实验室
  • 药明康德
  • Promega公司
  • 默克公司
  • 安捷伦科技公司, Inc.
  • Biovia(达索系统)
  • Cyprotex Limited
  • Bio-Rad Laboratories
  • IQVIA Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is meant by the pharma ADMET testing?

ADMET testing expands as for absorption, distribution, metabolism, elimination, and toxicology testing of the drug molecule. These drug tests define the impact of a specific drug or chemical on human tissues. Toxicology testing is an important phenomenon before introducing new medicine to the market. ADMET testing facilitates pharmaceutical manufacturing companies to minimize their drug discovery time, and testing complications, and reduce the cost of drug development.

What are the driving factors for the pharma ADMET testing market across the globe?

High rate of late-stage drug failure and the increasing number of product approvals and launches are the most significant factors responsible for the overall market growth.

Which segment led the pharma ADMET testing market?

Based on testing type, the market is segmented into in vivo ADMET testing, in vitro ADMET testing, and in silico ADMET testing. In vivo ADMET testing segment is anticipated to hold a larger share in 2022 and is expected to continue to do so during the forecast period.

Who are the key players in the pharma ADMET testing market?

CMIC HOLDINGS Co., LTD; Charles River Laboratories; WuXi AppTec; Promega Corporation; MERCK KGaA; Agilent Technologies, Inc.; Biovia (Dassault Systèmes); Cyprotex Limited; Bio-Rad Laboratories, Inc.; and IQVIA Inc. are among the leading companies operating in the global pharma ADMET testing market.

The List of Companies - Pharma ADMET Testing Market

  1. CMIC HOLDINGS Co., LTD
  2. Charles River Laboratories
  3. Wuxi AppTec
  4. Promega Corporation
  5. MERCK KGaA
  6. Agilent Technologies, Inc.
  7. Biovia (Dassault Systèmes)
  8. Cyprotex Limited
  9. Bio-Rad Laboratories, Inc.
  10. IQVIA Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

Your data will never be shared with third parties, however, we may send you information from time to time about our products that may be of interest to you. By submitting your details, you agree to be contacted by us. You may contact us at any time to opt-out.

Related Reports