蛋白质结合测定市场基于(关键地区、市场参与者、规模和份额)- 到 2031 年的预测

  • Report Code : TIPRE00004168
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 145
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蛋白质结合检测市场预计将从 2021 年的 3.4014 亿美元增至 2028 年的 6.9463 亿美元;预计 2021 年至 2028 年复合年增长率为 10.7%。

蛋白质结合测定有助于分析两种类型蛋白质之间的相互作用。这些检测方法广泛用于新药开发过程。

蛋白质结合检测市场根据技术、最终用户和地理位置进行细分。按地理位置划分,市场大致分为北美、欧洲、亚太地区、中东和非洲、以及南美洲和中美洲。该报告提供了对市场的洞察和深入分析,重点关注市场趋势、技术进步和市场动态等参数,并分析了全球领先市场参与者的竞争格局。       

蛋白质结合检测市场利润丰厚的区域


市场洞察

不断增长的药物发现活动推动蛋白质结合测定市场增长

临床试验是确定目标的关键且重要的一步商业用途的医疗策略、治疗和设备的安全性和有效性。这些研究还有助于了解和确定特定治疗领域的最佳医疗方法。药物分子或医疗器械在获得监管机构批准之前,需要进行一系列的临床研究。传染性和非传染性疾病的日益流行引发了对新药和医疗设备开发的需求,这反过来又推动了对蛋白质结合测定的需求。根据美国国家医学图书馆的数据,2018 年,50 个州和 204 个国家正在进行约 280,801 项临床研究。下图显示了2015年至2020年期间注册研究数量的增长情况。

  1. 临床试验注册研究数量
< td>

年初学习

24,130 p>

首次发布年份

年内学习

年末学习

2015

181,304

24,130

205,434

2016

205,434

27,809

233,243

2017

233,243

29,198

262,441

2018

262,441

17,836< /p>

280,277

2019

293,275

32,519

325,794

< p>2020

325,794

36,740

362,534

362,534

p>


此外,制药、医疗器械和生物技术公司专注于研发 (R&D) 活动开发具有最大医疗和商业潜力的治疗应用新分子。这些公司主要投资于研发,旨在向市场提供高质量和创新的产品。

  1. 2019 年十大制药研发支出
  2. < /ol>

    公司名称 (研发预算占收入的百分比)

    公司名称(研发预算占收入的百分比)

    1。 F.霍夫曼拉罗氏有限公司 (19.0%)

    2.强生公司约翰逊服务公司 (13.8%)

    3.默克集团 (21.1%)

    4.诺华公司 (19.8%)

    5.辉瑞公司 (16.7%)

    6。赛诺菲公司 (16.7%)

    7.艾伯维公司 (19.0%)

    8.百时美施贵宝有限公司 (23.6%)

    9.阿斯利康公司(24.8%)

    10。葛兰素史克 (13.8%)


    在药物开发过程的早期阶段,蛋白质结合测定正在开发中。由于未结合的循环药物最容易到达靶点和排泄途径,因此候选药物与血浆蛋白的结合对于药物分布、疗效和安全裕度定义至关重要。据Statista统计,2017年约有7,493种药物进入临床前阶段,预计2018年这一数字将达到8,040种。因此,每年筛选的候选药物总数都在增加。蛋白质结合研究在药物开发过程的早期进行,是临床前阶段的一个重要方面。因此,药物发现活动的增加以及药物研发支出的增加推动了蛋白质结合测定市场的增长。

    降低药物发现和开发成本的不断增长的需求极大地促进了蛋白质结合测定市场的增长

    开发新药的成本在通货膨胀率下仍然很高,投资回报和利润正在下降,给整个创新药物系统带来压力。由于当前降低医疗成本的经济和政治压力,许多制药和生物制药研究公司正在重新评估旧的研发政策,并将重点放在提高效率、增加产量和满足未满足的患者需求上。对药物发现和开发的关注点不断变化,以及越来越多地使用新技术来识别和筛选候选药物,使研究人员能够深入研究以前未针对的各种慢性、退行性和危及生命的疾病领域。
    < br />

    药物发现和开发是一个成本高昂的过程,因为它需要资金、人力资源和技术方面的投资。新药上市前,需要严格遵守检测规定和生产标准。此外,候选药物在开发阶段的失败会导致全部投资的浪费。蛋白质结合研究有助于评估临床前阶段的结合和吸收能力,从而降低开发后期阶段的药物损耗,从而有助于优化药物发现费用。因此,降低药物发现和开发过程成本的需求不断增长,推动了蛋白质结合测定市场的增长。

    技术洞察             

    根据技术,全球蛋白质结合检测市场分为超速离心、超滤、平衡透析、表面等离子体等。 2020年,平衡透析细分市场占据最大市场份额。然而,预计超滤细分市场将在 2021 年至 2028 年实现最高的复合年增长率。平衡透析是最广泛接受的评估蛋白质结合的方法之一,可以在快速平衡透析 (RED) 装置的帮助下进行。研究人员更喜欢这种方法,因为它对影响研究结果的无关因素和非预期因素的结合作用较小。

    最终用户洞察

    根据最终用户,蛋白质结合测定市场分为合同研究组织、制药和生物技术公司、以及研究和诊断实验室。制药和生物技术公司预计将在 2021 年占据最大的市场份额。到 2028 年,预计将成为市场的最大股东。这些公司是 CRO 服务的主要采用者;他们联系 CRO 外包药物和分子研究与开发。蛋白质结合是一个基本的生化过程,用于研究药物的机制及其对受试者的药理作用。这些方面正在推动制药和生物技术公司领域的蛋白质结合测定市场。   

    蛋白质结合检测市场(按技术) 2021年和2028年


    战略洞察

    产品发布、并购被高度采用全球蛋白质结合分析市场参与者的策略。近期重点产品开发如下:

    2020年11月,康龙化成北京有限公司以高达1000万元收购美国Absorbent Systems 100%资产现金1.375亿美元。 Absorbent Systems 是一家领先的科学非临床合同研究组织 (CRO),为制药、生物技术和医疗器械公司提供小分子和大分子、细胞和基因疗法以及眼科和医疗器械产品等;监管机构;以及研究和测试机构。

    2020年4月,赛多利斯成功收购丹纳赫生命科学公司部分资产。该交易在获得所需的监管批准后完成。

    在 COVID-19 大流行期间,针对该疾病的药物和疫苗的研发步伐有所加快。蛋白质结合是药物开发过程中研究的关键生化现象之一,因为感染因子或药物分子上的抗原所附着的细胞受体本质上大多是蛋白质。因此,投资于产品创新的制药和生物技术公司经常需要蛋白质结合测定材料和设备。

    蛋白质结合测定 –市场细分

    全球蛋白质结合测定市场根据技术、最终用户和地理位置进行细分。按技术划分,市场分为超速离心、超滤、平衡透析、表面等离子体等。根据最终用户,蛋白质结合测定市场分为合同研究组织、制药和生物技术公司以及研究和诊断实验室。按地理位置划分,市场大致分为北美、欧洲、亚太地区、中东和非洲、以及南美洲和中美洲。

    公司简介

    • Thermo Fisher Scientific, Inc.
    • 默克公司
    • < li>Eurofins Scientific
    • 通用电气公司
    • Sovicell GmbH
    • 康龙化成北京有限公司
    • Biotium, Inc.
    • li>
    • MicroConstants, Inc.
    • Sartorius AG
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is protein binding assay?

Protein binding assay is method or a procedure that assist in analyzing the interaction between two types of proteins. The protein binding assays are widely used in the process of the new drug development. The thermophoresis techniques are expected to analyze the interaction between the proteins.

What are the driving factors for the protein binding assay market across the globe?

Key factors driving the growth of the market are growing drug discovery activities and pharmaceutical R&D expenditure and rising pressure to reduce drug discovery and development costs are boosting the market. However, challenges with existing technologies are likely to hinder the market’s growth.

Which are the key players in the protein binding assay market?

Key players in the market are Thermo Fisher Scientific, Inc., Merck KGaA, Eurofins Scientific, General Electric Company, Sovicell GmbH, Pharmaron Beijing Co., Ltd., Biotium, Inc., MicroConstants, Inc. and Sartorius AG among others.

What is the regional market scenario of protein binding assay?

Global protein binding assay market is segmented by region into North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America. The North American region holds the largest market share of the market, whereas the Asia Pacific region is the fastest-growing region. The growth factors that are contributing to market’s growth in the North American region are growing elevation in research and development expenditures by the healthcare and life sciences companies in the region, especially in the US and Canada.

What are the report segments in the global protein binding assay market?

The global protein binding assay market is segmented on the bases of technology, end user, and geography. The market, by technology, is segmented into ultracentrifugation ultrafiltration, equilibrium dialysis, surface plasmon, and others. Based on end user, the protein binding assay market is segmented into contract research organizations, pharmaceutical and biotechnology companies, and research and diagnostic laboratories. The market, by geography, is broadly segmented into North America, Europe, Asia Pacific, the Middle East and Africa, and South and Central America.

What are the future trends in the global protein binding assay market?

Label-free receptor assays to emerge as powerful assay platform in coming years are the future trends in the global protein binding assay market.

The List of Companies - Protein Binding Assay Market

  1. Thermo Fisher Scientific, Inc.
  2. Merck KGaA
  3. Eurofins Scientific
  4. General Electric Company
  5. Sovicell GmbH
  6. Pharmaron Beijing Co., Ltd.
  7. Biotium, Inc.
  8. MicroConstants, Inc.
  9. Sartorius AG

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

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  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

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  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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