Rapporto sull’analisi delle dimensioni e delle quote del mercato della scoperta di farmaci a piccole molecole | Previsioni 2031

  • Report Code : TIPRE00004774
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 173
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Il mercato della scoperta di farmaci basati su piccole molecole è stato valutato a 24.976,14 milioni di dollari nel 2019 e si prevede che raggiungerà 50.823,06 milioni di dollari entro il 2027; si prevede che crescerà a un CAGR del 9,5% dal 2020 al 2027.

I farmaci a piccole molecole vengono utilizzati nella somministrazione mirata di farmaci in cui piccole molecole passano attraverso la membrana cellulare e agisce sullo specifico organello cellulare o proteina. I farmaci a piccole molecole sono in grado di entrare facilmente nelle cellule a causa del loro basso peso molecolare. Queste molecole sono migliori degli anticorpi monoclonali e di altri farmaci con molecole di grandi dimensioni grazie alle loro dimensioni, alla facile convertibilità in forma orale e al rapporto costo-efficacia. Si prevede che il mercato della scoperta di farmaci a piccole molecole vedrà un’enorme crescita dovuta alla crescente approvazione di farmaci a piccole molecole, alla crescente domanda di ricerca e sviluppo da parte di organizzazioni a contratto e alla crescente adozione di piccole molecole nei trattamenti delle malattie croniche. Tuttavia, si prevede che gli elevati costi di sviluppo dei farmaci freneranno la crescita del mercato durante il periodo di previsione.

Regioni redditizie per il mercato della scoperta di farmaci a piccole molecole< br />

Approfondimenti di mercato

Crescente adozione di piccole molecole nella cura delle malattie croniche

< p>Secondo i Centers for Disease Control (CDC), 6 adulti su 10 soffrono di patologie croniche, come malattie cardiache, diabete, cancro, malattie renali, malattie polmonari o ictus negli Stati Uniti, che costano 3,5 trilioni di dollari annualmente l’economia degli Stati Uniti per il trattamento di queste malattie croniche. Le malattie croniche rappresentano la causa più significativa di morte in tutto il mondo e il loro numero cresce ogni anno. Ad esempio, secondo il CDC, ogni anno negli Stati Uniti viene diagnosticato un cancro a più di 1,6 milioni di persone.

Si prevede che i farmaci a piccole molecole forniranno opzioni terapeutiche efficaci per malattie croniche a causa delle loro dimensioni e della capacità di attraversare le barriere cellulari. Possono anche essere progettati per attraversare la barriera emato-encefalica per colpire le malattie neurologiche. Si prevede che le piccole molecole svolgano un ruolo fondamentale nel ridurre il peso delle malattie croniche. Nei prossimi anni, si prevede che le piccole molecole contribuiranno alla formulazione di trattamenti più efficienti ed efficaci per le condizioni croniche.

Approfondimenti basati sull'area terapeutica

In base all'area terapeutica, il mercato della scoperta di farmaci a piccole molecole è segmentato in oncologia, sistema nervoso centrale, cardiovascolare, respiratorio, ortopedia, immunologia, malattie rare e altre aree terapeutiche. Il segmento oncologico ha detenuto la quota maggiore del mercato nel 2019 a causa delle crescenti approvazioni di farmaci a piccole molecole e della crescente pipeline per le terapie antitumorali. Inoltre, i crescenti investimenti in oncologia stanno ulteriormente guidando la crescita del segmento. Ad esempio, nel dicembre 2019, Zentalis Pharmaceuticals, un'azienda biofarmaceutica in fase clinica focalizzata sullo sviluppo di nuove terapie a base di piccole molecole clinicamente differenziate che mirano ai percorsi fondamentali del cancro, ha completato un finanziamento di serie C di 85 milioni di dollari. Tuttavia, si prevede che il segmento delle malattie rare registrerà un CAGR più elevato nel mercato durante il periodo di previsione.

Mercato globale della scoperta di farmaci a piccole molecole, per area terapeutica: 2019 e 2027

Approfondimenti basati su processo/fase

Basato su processo/fase, il mercato della scoperta di farmaci a piccole molecole è segmentato in scoperta del target, convalida del target, generazione e perfezionamento di lead e sviluppo preclinico. Nel 2019, il segmento della lead generation e del perfezionamento ha detenuto la quota maggiore del mercato globale della scoperta di farmaci basati su piccole molecole, grazie ai crescenti investimenti nella scoperta di farmaci e alla crescente domanda di terapie economicamente vantaggiose. Inoltre, la scoperta del bersaglio comporta l’identificazione di bersagli modificanti la malattia, che costituisce uno dei passaggi essenziali nella pipeline di scoperta dei farmaci. Tuttavia, si prevede che la scoperta del target registrerà il CAGR più elevato durante il periodo di previsione.

Approfondimenti strategici

Le collaborazioni e la strategia di espansione sono comunemente adottate da aziende di espandere la propria presenza in tutto il mondo e soddisfare la crescente domanda al fine di espandere il proprio portafoglio di prodotti.

Gli operatori di mercato che operano nel mercato della scoperta di farmaci a piccole molecole hanno adottato la strategia del prodotto innovazione per soddisfare la mutevole domanda dei clienti in tutto il mondo, il che consente anche agli attori di mantenere il proprio marchio a livello globale.

Mercato della scoperta di farmaci per piccole molecole: – Per area terapeutica

  • Oncologia
  • Sistema nervoso centrale
  • Cardiovascolare
  • Respiratorio
  • Ortopedia
  • Immunologia
  • Malattie rare
  • Altre aree terapeutiche

Mercato della scoperta di farmaci a piccole molecole - Per processo/fase

  • Scoperta del target
  • Convalida del target
  • Generazione e perfezionamento dei lead
  • Sviluppo preclinico
  • < /ul>

    Mercato della scoperta di farmaci a piccole molecole– Per area geografica

    • Nord America
      • Stati Uniti
      • Canada
      • Messico
    • < li>Europa
      • Francia
      • Germania
      • Italia
      • Regno Unito
      • Spagna
      • Resto dell'Europa
    • Asia Pacifico (APAC)
      • Cina
      • India
      • Corea del Sud
      • Giappone
      • Australia
      • Resto dell'area APAC
    • Medio Oriente e Africa (MEA)
      • Sud Africa
      • Arabia Saudita
      • Emirati Arabi Uniti
      • Resto del MEA
    • Sud America (SAM)< ul>
    • Brasile
    • Argentina
    • Resto della SAM
< h3>Profili aziendali
  • Johnson and Johnson Services, Inc.
  • Teva Pharmaceutical Industries Ltd
  • Boehringer Ingelheim International GmbH
  • Allergan Plc.
  • Pfizer Inc.
  • Bristol-Myers Squibb Company
  • MERCK KGaA
  • GlaxoSmithKline plc.
  • AstraZeneca
  • Gilead Sciences, Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is small molecule drug discovery market?

Small molecules drugs are used in targeted drug delivery in which small molecules pass through the cell membrane and acts on the specific cellular organelle or protein. The small molecules drugs are able to enter cells easily because of its low molecular weight. These molecules are better than monoclonal antibodies and other large molecule drugs due to their size, easy convertibility to oral form and cost affectivity. The discovery of novel small molecule entities that are capable of specific interactions represents a significant challenge in the early stages of drug discovery. When the biological target is well defined and understood, the rational design of small molecule ligands is possible. In the recent years, the small molecules have witnessed significant attention over biologics, as there is an increasing demand for these drugs.

What are the driving factors for the small molecule drug discovery market across the globe?

The factors that are driving growth of the market are increasing approval of small molecule drugs, growing demand for R&D from contract organizations, and rising adoption of small molecules in chronic disease treatments propel the growth of the market.

Who are the major players in the small molecule drug discovery market?

The small molecule drug discovery market majorly consists of the players such as Pfizer Inc., Bristol-Myers Squibb Company, Merck KGaA, GlaxoSmithKline Plc, AstraZeneca, Johnson & Johnson Services, Inc., TEVA PHARMACEUTICAL INDUSTRIES LTD, Boehringer Ingelheim International GmbH, and Allergan Plc.

The List of Companies - Small Molecule Drug Discovery Market

  1. Johnson and Johnson Services, Inc.
  2. Teva Pharmaceutical Industries Ltd
  3. Boehringer Ingelheim International GmbH
  4. Allergan Plc.
  5. Pfizer Inc.
  6. Bristol-Myers Squibb Company
  7. MERCK KGaA
  8. GlaxoSmithKline plc.
  9. AstraZeneca
  10. Gilead Sciences, Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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