저분자 약물 발견 시장 조사 – 규모, 점유율, 개발 및 미래 범위 2031

  • Report Code : TIPRE00004774
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 173
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저분자 신약 발견 시장은 2019년에 US$ 24,976.14백만으로 평가되었으며, 2027년에는 US$ 50,823.06Mn에 이를 것으로 예상됩니다. 2020년부터 2027년까지 연평균 성장률(CAGR) 9.5%로 성장할 것으로 예상됩니다.

소분자 약물은 소분자가 세포막을 통과하는 표적 약물 전달에 사용됩니다. 특정 세포 소기관이나 단백질에 작용합니다. 저분자 약물은 분자량이 낮기 때문에 세포에 쉽게 들어갈 수 있습니다. 이들 분자는 크기, 경구 형태로의 쉬운 전환성, 비용 효율성으로 인해 단일클론 항체 및 기타 거대 분자 약물보다 우수합니다. 저분자 신약 발견 시장은 저분자 의약품의 승인 증가, 계약 기관의 R&D 수요 증가, 만성 질환 치료에서 저분자 채택 증가로 인해 큰 성장을 보일 것으로 예상됩니다. 그러나 예측 기간 동안 높은 약물 개발 비용으로 인해 시장 성장이 제한될 것으로 예상됩니다.

소분자 약물 발견 시장의 수익성이 높은 지역< br />

시장 통찰력

만성 질환 치료에서 소분자 채택 증가

< p>질병통제센터(CDC)에 따르면 미국 성인 10명 중 6명은 심장 질환, 당뇨병, 암, 신장 질환, 폐 질환, 뇌졸중 등의 만성 질환을 앓고 있으며, 이에 따른 비용은 미화 3조 5천억 달러에 이릅니다. 이러한 만성 질환 치료를 위해 매년 미국 경제가 성장하고 있습니다. 만성질환은 전 세계적으로 사망의 가장 큰 원인이며, 그 수는 매년 증가하고 있습니다. 예를 들어, CDC에 따르면 미국에서는 매년 160만 명 이상이 암 진단을 받습니다.

저분자 의약품은 다음과 같은 환자에게 효과적인 치료 옵션을 제공할 것으로 예상됩니다. 만성 질환은 크기와 세포 장벽을 통과하는 능력으로 인해 발생합니다. 또한 신경 질환을 표적으로 삼기 위해 혈액뇌관문을 통과하도록 설계될 수도 있습니다. 소분자는 만성질환의 부담을 줄이는 데 중요한 역할을 할 것으로 기대됩니다. 앞으로 몇 년 안에 저분자는 만성 질환에 대한 보다 효율적이고 효과적인 치료법을 개발하는 데 도움이 될 것으로 예상됩니다.

치료 영역 기반 통찰력

치료 분야를 기준으로 저분자 신약 발견 시장은 종양학, 중추신경계, 심혈관, 호흡기, 정형외과, 면역학, 희귀 질환 및 기타 치료 분야로 분류됩니다. 종양학 부문은 소분자 약물 승인 증가와 암 치료제 파이프라인 증가로 인해 2019년 시장에서 가장 큰 점유율을 차지했습니다. 더욱이 종양학에 대한 투자 증가는 해당 부문의 성장을 더욱 촉진하고 있습니다. 예를 들어, 2019년 12월, 암의 기본 경로를 목표로 하는 임상적으로 차별화된 새로운 소분자 치료제 개발에 주력하는 임상 단계 바이오제약 회사인 Zentalis Pharmaceuticals는 미화 8,500만 달러 규모의 시리즈 C 자금 조달을 완료했습니다. 그러나 희귀질환 부문은 예측 기간 동안 시장에서 더 높은 CAGR을 기록할 것으로 예상됩니다.

치료 분야별 글로벌 소분자 신약 발견 시장 – 2019 & 2027

과정/단계 기반 통찰력

과정/단계 기반 저분자 약물 발견 시장 표적 발견, 표적 검증, 리드 생성 및 개선, 전임상 개발로 분류됩니다. 리드 생성 및 정제 부문은 신약 발견에 대한 투자 증가와 비용 효과적인 치료법에 대한 수요 증가로 인해 2019년 전 세계 소분자 신약 발견 시장에서 가장 큰 점유율을 차지했습니다. 또한, 표적의 발견에는 질병 수정 표적의 식별이 포함되며 이는 약물 발견 파이프라인의 필수 단계 중 하나입니다. 그러나 표적 발견은 예측 기간 동안 가장 높은 CAGR을 기록할 것으로 예상됩니다.

전략적 통찰력

협력 및 확장 전략은 일반적으로 다음과 같은 기업에서 채택됩니다. 회사는 제품 포트폴리오를 확장하기 위해 전 세계적으로 입지를 확장하고 증가하는 수요를 충족하기 위해 노력하고 있습니다.

저분자 약물 발견 시장에서 활동하는 시장 참가자들은 제품 전략을 채택했습니다. 전 세계적으로 변화하는 고객 수요에 부응하기 위한 혁신을 통해 플레이어는 전 세계적으로 브랜드 이름을 유지할 수 있습니다.

소분자 약물 발견 시장 – 치료 분야별

  • 종양학
  • 중추신경계
  • 심혈관
  • 호흡기
  • 정형외과
  • li>
  • 면역학
  • 희귀질환
  • 기타 치료 분야

소분자 약물 발견 시장 – 프로세스/단계별

  • 표적 발견
  • 표적 검증
  • 리드 생성 및 개선
  • 전임상 개발
  • < /ul>

    소분자 신약 발굴 시장– 지역별

    • 북미
      • 미국
      • 캐나다
      • 멕시코
    • < li>유럽
      • 프랑스
      • 독일
      • 이탈리아
      • 영국
      • 스페인
      • 나머지 유럽
    • 아시아 태평양(APAC)
      • 중국
      • 인도
      • 대한민국
      • 일본
      • 호주
      • 나머지 APAC
    • 중동 및 아프리카(MEA)
      • 남아프리카
      • 사우디아라비아
      • UAE
      • 나머지 MEA
    • 남아메리카(SAM)< ul>
    • 브라질
    • 아르헨티나
    • SAM의 나머지 지역
< h3>회사 프로필
  • Johnson and Johnson Services, Inc.
  • Teva Pharmaceutical Industries Ltd
  • Boehringer Ingelheim International GmbH
  • Allergan Plc.
  • Pfizer Inc.
  • Bristol-Myers Squibb Company
  • MERCK KGaA
  • GlaxoSmithKline plc.
  • AstraZeneca
  • Gilead Sciences, Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is small molecule drug discovery market?

Small molecules drugs are used in targeted drug delivery in which small molecules pass through the cell membrane and acts on the specific cellular organelle or protein. The small molecules drugs are able to enter cells easily because of its low molecular weight. These molecules are better than monoclonal antibodies and other large molecule drugs due to their size, easy convertibility to oral form and cost affectivity. The discovery of novel small molecule entities that are capable of specific interactions represents a significant challenge in the early stages of drug discovery. When the biological target is well defined and understood, the rational design of small molecule ligands is possible. In the recent years, the small molecules have witnessed significant attention over biologics, as there is an increasing demand for these drugs.

What are the driving factors for the small molecule drug discovery market across the globe?

The factors that are driving growth of the market are increasing approval of small molecule drugs, growing demand for R&D from contract organizations, and rising adoption of small molecules in chronic disease treatments propel the growth of the market.

Who are the major players in the small molecule drug discovery market?

The small molecule drug discovery market majorly consists of the players such as Pfizer Inc., Bristol-Myers Squibb Company, Merck KGaA, GlaxoSmithKline Plc, AstraZeneca, Johnson & Johnson Services, Inc., TEVA PHARMACEUTICAL INDUSTRIES LTD, Boehringer Ingelheim International GmbH, and Allergan Plc.

The List of Companies - Small Molecule Drug Discovery Market

  1. Johnson and Johnson Services, Inc.
  2. Teva Pharmaceutical Industries Ltd
  3. Boehringer Ingelheim International GmbH
  4. Allergan Plc.
  5. Pfizer Inc.
  6. Bristol-Myers Squibb Company
  7. MERCK KGaA
  8. GlaxoSmithKline plc.
  9. AstraZeneca
  10. Gilead Sciences, Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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