低分子創薬市場 - 2031年の成長予測、統計および事実

  • Report Code : TIPRE00004774
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 173
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低分子創薬市場は、2019 年に 249 億 7,614 万米ドルと評価され、2027 年までに 508 億 2,306 万米ドルに達すると予測されています。 2020 年から 2027 年にかけて 9.5% の CAGR で成長すると予想されています。

小分子薬は、小分子が細胞膜を通過する標的薬物送達に使用されます。特定の細胞小器官またはタンパク質に作用します。小分子薬は分子量が低いため、細胞に容易に侵入できます。これらの分子は、そのサイズ、経口剤への容易な変換性、および費用対効果の点で、モノクローナル抗体や他の高分子薬剤よりも優れています。小分子創薬市場は、小分子医薬品の承認の増加、受託機関からの研究開発需要の増大、慢性疾患治療における小分子の採用の増加により、大幅な成長が見込まれています。ただし、高い医薬品開発コストが予測期間中の市場の成長を抑制すると予想されます。

低分子創薬市場の有利な地域< br />

市場洞察

慢性疾患治療における低分子の採用の増加

< p>疾病管理センター (CDC) によると、米国では成人 10 人中 6 人が心臓病、糖尿病、がん、腎臓病、肺疾患、脳卒中などの慢性疾患を患っており、医療費は 3 兆 5,000 億米ドルに上っています。これらの慢性疾患の治療のために米国経済は毎年増加しています。慢性疾患は世界中で最も重要な死因であり、その数は年々増加しています。たとえば、CDC によると、米国では毎年 160 万人以上ががんと診断されています。

低分子医薬品は、以下の疾患に効果的な治療選択肢を提供すると期待されています。そのサイズと細胞障壁を通過する能力により、慢性疾患に影響を及ぼします。また、神経疾患を標的とするために血液脳関門を通過するように設計することもできます。小分子は、慢性疾患の負担を軽減する上で重要な役割を果たすことが期待されています。今後数年間で、低分子は慢性疾患に対するより効率的かつ効果的な治療法の策定に役立つと期待されています。

治療領域に基づく洞察

低分子創薬市場は、治療領域に基づいて、腫瘍学、中枢神経系、心血管、呼吸器、整形外科、免疫学、希少疾患、その他の治療領域に分割されています。腫瘍学分野は、小分子薬の承認の増加とがん治療薬のパイプラインの拡大により、2019年に市場で最大のシェアを占めました。さらに、腫瘍学への投資の増加がこの分野の成長をさらに推進しています。たとえば、2019年12月、臨床段階のバイオ医薬品会社であるゼンタリス・ファーマシューティカルズは、がんの基本経路を標的とする臨床的に差別化された新規小分子治療薬の開発に注力し、8,500万米ドルのシリーズC資金調達を完了した。ただし、希少疾患セグメントは、予測期間中に市場でより高いCAGRを記録すると予想されます。

世界の低分子創薬市場、治療分野別 – 2019年& 2027 年

プロセス/フェーズベースの洞察

プロセス/フェーズに基づく低分子創薬市場は、ターゲットの発見、ターゲットの検証、リードの生成と改良、前臨床開発に分類されます。リード生成および精製セグメントは、創薬への投資の増加と費用対効果の高い治療薬の需要の高まりにより、2019年に世界の小分子創薬市場で最大のシェアを占めました。さらに、標的の発見には疾患修飾標的の同定が含まれ、これは創薬パイプラインの重要なステップの 1 つとして機能します。ただし、ターゲットの発見は、予測期間中に最高の CAGR を記録すると予想されます。

戦略的洞察

コラボレーションと拡張戦略は、一般的に採用されています。企業は、製品ポートフォリオを拡大するために世界中に拠点を拡大し、増大する需要に対応する必要があります。

小分子創薬市場で活動する市場プレーヤーは、製品戦略を採用しました。世界中で変化する顧客需要に応えるためのイノベーションにより、プレーヤーは世界的にブランド名を維持することも可能になります。

低分子創薬市場 –治療分野別

  • 腫瘍学
  • 中枢神経系
  • 心臓血管
  • 呼吸器
  • 整形外科
  • 免疫学
  • 希少疾患
  • その他の治療分野

低分子創薬市場 –プロセス/フェーズ別

  • ターゲットの発見
  • ターゲットの検証
  • リードの生成と絞り込み
  • 前臨床開発
  • < /ul>

    低分子創薬市場–地理別

    • 北アメリカ
      • 米国
      • カナダ
      • メキシコ
    • < li>ヨーロッパ
      • フランス
      • ドイツ
      • イタリア
      • イギリス
      • スペイン
      • 残りヨーロッパ
    • アジア太平洋(APAC)
      • 中国
      • インド
      • 韓国
      • 日本
      • オーストラリア
      • アジア太平洋地域のその他の地域
    • 中東およびアフリカ (MEA)
      • 南アフリカ
      • サウジアラビア
      • アラブ首長国連邦
      • MEAの残りの部分
    • 南アメリカ(SAM)< ul>
    • ブラジル
    • アルゼンチン
    • SAM の残りの部分
< h3>会社概要
  • Johnson and Johnson Services, Inc.
  • Teva Pharmaceutical Industries Ltd
  • Boehringer Ingelheim International GmbH
  • Allergan Plc.
  • Pfizer Inc.
  • Bristol-Myers Squibb Company
  • MERCK KGaA
  • GlaxoSmithKline plc.
  • >アストラゼネカ
  • ギリアド・サイエンシズ社
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

This text is related
to segments covered.

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

This text is related
to country scope.

Frequently Asked Questions


What is small molecule drug discovery market?

Small molecules drugs are used in targeted drug delivery in which small molecules pass through the cell membrane and acts on the specific cellular organelle or protein. The small molecules drugs are able to enter cells easily because of its low molecular weight. These molecules are better than monoclonal antibodies and other large molecule drugs due to their size, easy convertibility to oral form and cost affectivity. The discovery of novel small molecule entities that are capable of specific interactions represents a significant challenge in the early stages of drug discovery. When the biological target is well defined and understood, the rational design of small molecule ligands is possible. In the recent years, the small molecules have witnessed significant attention over biologics, as there is an increasing demand for these drugs.

What are the driving factors for the small molecule drug discovery market across the globe?

The factors that are driving growth of the market are increasing approval of small molecule drugs, growing demand for R&D from contract organizations, and rising adoption of small molecules in chronic disease treatments propel the growth of the market.

Who are the major players in the small molecule drug discovery market?

The small molecule drug discovery market majorly consists of the players such as Pfizer Inc., Bristol-Myers Squibb Company, Merck KGaA, GlaxoSmithKline Plc, AstraZeneca, Johnson & Johnson Services, Inc., TEVA PHARMACEUTICAL INDUSTRIES LTD, Boehringer Ingelheim International GmbH, and Allergan Plc.

The List of Companies - Small Molecule Drug Discovery Market

  1. Johnson and Johnson Services, Inc.
  2. Teva Pharmaceutical Industries Ltd
  3. Boehringer Ingelheim International GmbH
  4. Allergan Plc.
  5. Pfizer Inc.
  6. Bristol-Myers Squibb Company
  7. MERCK KGaA
  8. GlaxoSmithKline plc.
  9. AstraZeneca
  10. Gilead Sciences, Inc.

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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