Clinical Trial Imaging Market Trends Report | Growth & Size 2028

Clinical Trial Imaging Market Forecast to 2028 - Global Analysis By Modality [Tomography, Magnetic Resonance Imaging (MRI), Ultrasound, Positron Emission Tomography (PET), X-Ray, Echocardiography, and Others], Offering (Operational Imaging Services, Imaging Software, Read Analysis Services, Trial Design and Consulting Services, and Others), and End User [Contract Research Organizations (CROs), Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, and Others]

Publication Month : May 2023

  • Report Code : TIPHE100001201
  • Category : Pharmaceuticals
  • Status : Published
  • No. of Pages : 186
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[Research Report] The clinical trial imaging market size is expected to reach US$ 2,480.32 million by 2028 from US$ 1,610.70 million in 2022; it is estimated to record a CAGR of 7.6% from 2023 to 2028.

Market Insights and Analyst View:

Clinical trial imaging is a research study conducted with people who volunteer to take part. The study mainly aims to determine the value of imaging procedures for detecting, diagnosing, guiding, or monitoring the treatment of disease. Some image interpretation processes may include the use of test images intermixed among the clinical trial images such that readers are intermittently tested as to the proficiency and/or consistency in their reads. Failure to sustain proficiency may result in replacement of a reader with another trained and qualified reader. Rapid increase in utilization of imaging endpoints in multicenter clinical trials, the amount of data and workflow complexity have also increased. A Clinical Trial Imaging Management System (CTIMS) is required to comprehensively support imaging processes in clinical trials as to follow a seamless workflow and also improve patient outcomes. Key regulatory requirements of CTIMS were extracted through a thorough review of many related regulations and guidelines including International Conference on Harmonization-GCP E6, FDA 21 Code of Federal Regulations parts 11 and 820, Good Automated Manufacturing Practice, and Clinical Data Interchange Standards Consortium.

Growth Drivers and Challenges:

Clinical research organizations (CROs) assist in the successful implementation of clinical trials through the services offered using high-quality facilities and deep subject matter expertise. CROs have begun acting as a backbone of the clinical trial industry through their efficient and cost-effective operations that benefit trial sponsors. For example, on an average, CROs take 30% lesser time than in-house activity to conduct and complete clinical trials.

With the rising number of CROs leading to high competition, some of these businesses offer specialized imaging services, thus emerging as imaging CROs (iCROs). Keosys Medical Imaging and Medica Group PLC are the iCROs examples. The total number of clinical trials has doubled since 2010, and the use of imaging modalities in these trials has increased by almost 500%. Per a report by KEOSYS MEDICAL IMAGING company, iCROs allocate 7.5–10% of their budgets for imaging, which helps them optimize their workflow to manage every step of the process from image acquisition to interpretation. These CROs offer key knowledge insights in areas such as site qualification for imaging, acquisition of standardized images, and determination of read designs and criteria, thereby contributing to the growth of the global clinical trial imaging market

Clinical trials help determine if a new form of treatment or prevention, such as a new drug, diet, or medical device, is safe and effective. The trials are mainly carried out during drug development. According to the data provided by the National Library of Medicine (NLM), ~52,000 new studies were registered with NLM ( in 2020, which increased to ~58,000 in 2023. In January 2023, the NLM reported 38,837 active clinical trials in the US and 105,172 active trials worldwide. According to European Medicine Agency, in the European Union (EU), ~4,000 clinical trials are authorized annually, of which about 60% of clinical trials are associated with the pharmaceutical industry. An increasing number of clinical trials for developing different effective treatments due to the rising prevalence of chronic diseases globally is fuelling the growth of the clinical trial imaging market.

Further, clinical trials are increasingly becoming complex procedures, owing to which proper execution and overseeing of the operation occurring in research-based organizations has become crucial. To avoid errors due to improper execution, research-based organizations are outsourcing clinical trials to develop their products. Clinical research organizations (CROs) assist in successfully implementing clinical trials through the services offered using high-quality facilities and deep subject matter expertise. CROs have begun acting as a backbone of the clinical trial industry through their efficient and cost-effective operations benefitting trial sponsors. According to the blog published on Thermo Fisher Scientific, in 2022, ~3 out of 4 clinical trials were carried out by CROs to reassure the clinical programs of drug developers, provide a wealth of expertise, drive time and cost efficiencies, and deliver customized, high-quality data. Thus, the development of cost-effective solutions and decreasing errors in CROs during the drug development process are driving the clinical trial market growth, which in turn is increasing the clinical trials imaging market.

The pharmaceutical industry is one of the most R&D-intensive industries globally. The value of medicines is becoming increasingly important as pharmaceutical companies are keen to ensure that R&D achieves their intended goal. Over the last decade, the number of new drugs approved yearly has also increased. Per the Food and Drug Administration (FDA) approved 37 new drugs annually in 2022. Efforts are being made to achieve greater effectiveness and efficiency in fulfilling patients' needs. The research-based industry allocates ~15–20% of revenues to R&D activities and invests more than US$ 50 billion in R&D annually. Globally, the US is a leading country in R&D investments, producing over half of the world’s new molecules in the past decade. As per the European Federation of Pharmaceutical Industries and Associations (EFPIA), in 2019, North America accounted for 48.7% of global pharmaceutical sales. The US accounted for 62.3% of sales of new medicines launched during 2014–2019. R&D is a significant and essential part of the business of pharmaceutical companies as it enables them to come up with new molecules for various therapeutic applications with significant medical and commercial potential.

R&D Investments by Major Pharmaceuticals Companies


R&D Investment in 2021 (US$ Billion)

R&D Investment in 2022 (US$ Billion)

Takeda Pharmaceutical Co Ltd



Pfizer Inc



Grifols SA



Note: Current conversion rate is considered for presenting the currencies.

Source: Annual Reports and The Insight Partners Analysis

R&D expenditure is done to discover, examine, and produce new products; upfront payments; ; improve existing outcomes; and demonstrate product efficacy and regulatory compliance before launch. The R&D investments differ as per the need and demand for clinical trials. The cost includes materials, supplies used, and salaries, along with the cost of developing quality control.

The companies mentioned above and hospitals are investing in developing products to treat various diseases and disorders, such as immunological disorders. In June 2021, Takeda announced ADVANCE-1, a randomized, placebo-controlled, double-blind Phase 3 clinical trial that evaluate HYQVIA [Immune Globulin Infusion 10% (Human) with Recombinant Human Hyaluronidase] to maintain treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), that will meet its primary endpoint. Thus, increasing R&D investments by companies coupled with the advanced pharmaceutical industry are fueling the clinical trials imaging market growth.

For pharmaceutical and biopharmaceutical companies, active participation in clinical research is rewarding but demanding, and medical imaging is becoming an integral part of the research. However, the unique technical specifications and administrative aspects of clinical trial and imaging modalities vary substantially from standard-of-care imaging, thus burdening an established clinical infrastructure at investigational sites. Failure to comply with such clinical requirements results in the generation of noncredible data, need for repetitive imaging, and removal of patient enrollment for the trial. Further, the lack of appropriate infrastructure at investigational sites may hinder the efforts made by CROs to address such challenges. Clinical trial imaging equipment seeks hefty investments of resources from stakeholders. For example, drug or device investigational sites must meet clinical trial requirements and infrastructure, maintain superiority in patient care, and guarantee trial integrity. Moreover, clinical trial sponsors must acknowledge the burden of clinical trial imaging by providing support for the development of necessary local infrastructure for meeting the abovementioned requirements. The Quantitative Imaging Biomarkers Alliance by the Radiologic Society of North America seeks to define standard imaging protocols and workflows, ensuring consistency in the examination of images for producing quantifiable clinical trial results. Thus, high investments and standardized infrastructure requirements impede the growth of the global clinical trial imaging market.

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Clinical Trial Imaging Market: Strategic Insights

Market Size Value inUS$ 1,610.70 million in 2022
Market Size Value byUS$ 2,480.32 million by 2028
Growth rateCAGR of 7.6% from 2023 to 2028
Forecast Period2023-2028
Base Year2022
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Report Segmentation and Scope:

The “Global Clinical Trial Imaging Market” is segmented based on modality, offering, end user, and geography. Based on modality, the clinical trial imaging market is segmented into tomography, ultrasound, positron emission tomography, X-ray, echocardiography, magnetic resonance imaging, and others. Based on offering, the clinical trial imaging market is segmented into trial design consulting services, read analysis services, operational imaging services, imaging software, and others. Based on end user, the clinical trial imaging market is segmented into pharmaceutical & biopharmaceutical companies, contract research organizations, and academic & government research institutes, and others. The clinical trial imaging market based on geography is segmented into North America (the US, Canada, and Mexico), Europe (Germany, France, Italy, the UK, Russia, and Rest of Europe), Asia Pacific (Australia, China, Japan, India, South Korea, and Rest of Asia Pacific), the Middle East & Africa (South Africa, Saudi Arabia, the UAE, and Rest of the Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America).

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Segmental Analysis:

The global clinical trial imaging market, offering, has been segmented into trial design consulting services, read analysis services, operational imaging services, imaging software, and others. Operational imaging services segment held the largest share in 2021 and is expected to continue a similar trend during the forecast period. Operational imaging services include imaging modalities such as MRI, CT, ultrasound, PET, and SPECT for therapeutic applications such as neurology, oncology, cardiovascular diseases, gastroenterology, musculoskeletal disorders, and medical devices used to conduct clinical trials. Clinical imaging, a non-invasive method of research, has a number of advantages for the advancement of medical science in general, as well as clinical studies in particular. As a consequence, there is a strong and growing trend to incorporate novel imaging technologies deeply into clinical trials, making them a fundamental element of biotech, pharmaceuticals, and medical devices.

Also, choosing the right read design is crucial when executing imaging in a trial. The read design refers to the number and type of readers used to capture and interpret the images. Reducing variability leads to crucial challenges in image capture and analysis since trials can include imageries obtained from various imaging modalities, requiring a review by experts such as radiologists, pathologists, and cardiologists. The type of read design used is paramount to reduce bias when interpreting medical images in clinical trials. Single reads, double reads, and double reads with adjudicators are the three primary types of read designs. The image is interpreted only by one reader in a single read. In a double read, two or more readers interpret it. Large trials may require multiple readers due to a heavy workload. Ideally, one (or two in the case of a double-read design) reader(s) will review all the images of the same patient throughout the study. Multiple readers reviewing different imaging time points of the same patient may result in additional variations. An oncology trial, for instance, usually involves the following stages: initial screening for lesion selection and measurement before treatment, the sequential selection and measurement of a lesion at each follow-up imaging visit, and the assessment of incremental radiological response at each time point.

Keosys Medical Imaging offers web-based imaging and reading software for applications in clinical trials to limit reader subjectivity; increase measurement and quantification accuracy; and improve overall operational efficiency, data quality, and traceability. An advanced lesion management system and specialized applications for different therapeutic areas are included in the reading software offered by Keosys. The reading software is FDA 510 (k) cleared and ISO 13485 (Medical Devices) compliant.

Clinical Trial Imaging Market, by Offering– 2021 and 2028

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Based on modality, the clinical trial imaging market is into tomography, ultrasound, positron emission tomography, X-ray, echocardiography, magnetic resonance imaging, and others. Tomography segment held the largest share in 2021 and is expected to continue a similar trend during the forecast period. In tomography, shadows of superimposed structures are blurred by a moving X-ray tube that is used for X-ray imaging. Computed tomography (CT) scan imaging used in research and clinical trials combines X-ray images taken from different angles, followed by computer processing to provide cross-sectional images of bones, blood vessels, and soft tissues. Linear and nonlinear tomography systems operate in a similar way—a tube moves in one direction, while a film cassette moves in the opposite direction, centered around a fulcrum in both techniques.

The introduction of new imaging methods or the refinement of existing methods requires accurate timing in relation to specific disease treatment. Scheduling imaging at an apt time is essential for correctly interpreting the subject’s anatomy. In hospitals, it helps effectively administer treatments such as surgery, radiation therapy, or chemotherapy while monitoring the patient's toxicity and morbidity. Clinical research in the field of oncology relies heavily on imaging, and scanning procedures performed at certain durations, intensities, and frequencies are fundamental to the trial protocols.

Advanced imaging metrics with CT scans are used extensively in new drug development and cancer research. It is the most used imaging modality for research related to advanced cancer types, affecting the neck, chest, abdomen, or pelvis.

Regional Analysis:

Based on geography, the clinical trial imaging market is segmented into five key regions: North America, Europe, Asia Pacific, South & Central America, and the Middle East & Africa. In 2021, North America held the largest share of the clinical trial imaging market followed by Europe. The US has emerged as a leading clinical research destination. Nearly half of the total clinical trials conducted globally are conducted in the US. Additionally, most pharma research companies prefer to perform clinical trials in the US owing to established medical infrastructure, fast approval timelines, a favorable regulatory framework, and accepted clinical trial generated data globally. A World Health Organisation (WHO) report states that the US registered the highest number of clinical trials (157,618) in 2021.

The following table illustrates the number of clinical trials registered in the US with the number of total patients recruited in them, along with the percentage share of the US for the said parameters in the world.


Registered Clinical Trial Studies

Patient Recruited in Studies


139,632 (31% of the global studies)

20,680 (32% of the worldwide headcount)

Source: report

Innovative products launched by companies for applications in clinical trials further boost the growth of the clinical trial imaging market in the US. Medical Metrics, a CRO providing imaging services for clinical trials, offers "Assessa." This product assists in the improvement of decision-making in drug discovery and related clinical studies, particularly in the discovery of drugs for neurological disorders, such as dementia; cognitive impairment; and Alzheimer's, Schizophrenia, Parkinson's Disease, and other memory-related diseases. The rising number of clinical trials in the US favors the growth of the clinical trial imaging market in the country.

Industry Developments and Future Opportunities:

Various initiatives taken by key players operating in the global clinical trial imaging market are listed below:

  • In December 2022, Tata Consultancy Services (TCS) (BSE: 532540, NSE: TCS) announced that the TCS ADD Connected Clinical Trials platform for decentralized trials, has won the India Pharma Award 2022 in the category, Excellence in Ancillary Pharma Services.
  • In October 2021, Medidata, a Dassault Systèmes company, announced that Rave Imaging, the company’s cloud-based, secure clinical trial imaging management platform, has reached a significant milestone, having supported more than 1,000 imaging studies. Rave Imaging, built on the Medidata Unified Platform, processes more than 100 million images per year. The technology provides real-time visibility into all imaging-related trial activities across all Rave Imaging trials to enhance study efficiency.

Competitive Landscape and Key Companies:

The clinical trial imaging market majorly consists of players such as eResearch Technology Inc, Calyx Inc, ICON PLC, VIDA Diagnostics Inc, WCG Clinical Inc, BioTelemetry Inc, Medical Metrics Inc, Medpace Holdings Inc, Radiant Sage LLC, and IXICO plc. The companies have been implementing various strategies that have helped their growth and, in turn, have brought about various changes in the market. The companies have utilized organic strategies (such as launches, expansion, and product approvals) and inorganic strategies (such as product launches, partnerships, and collaborations).

Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Modality, Offering, and End User

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions

Who are the key players in the clinical trial imaging market?

The clinical trial imaging market majorly consists of the players such eResearch Technology Inc, Calyx Inc, ICON PLC, VIDA Diagnostics Inc, WCG Clinical Inc, BioTelemetry Inc, Medical Metrics Inc, Medpace Holdings Inc, Radiant Sage LLC, and IXICO plc. .

Which are the top companies that hold the market share in clinical trial imaging market?

ICON plc and Calyx Inc are the top two companies that hold huge market shares in the clinical trial imaging market.

Which modality segment leads the clinical trial imaging market?

Tomography segment held the largest share of the market in the clinical trial imaging market and held the largest market share in 2022.

Which offering held the largest share in the clinical trial imaging market?

The operational imaging services segment dominated the clinical trial imaging market and held the largest market share in 2022.

What are the driving factors for the clinical trial imaging market across the globe?

Key factors that are driving the growth of this market are accelerated clinical trial activities in pharmaceutical and biotechnology industry and spur in number of CROs offering medical imaging services to boost the market growth for the clinical trial imaging over the years.

What is the market CAGR value of clinical trial imaging market during forecast period?

The CAGR value of the clinical trial imaging market during the forecasted period of 2023-2028 is 7.6%.

What is Clinical Trial Imaging Market?

Clinical trial imaging is a key asset in the drug development process as it offers efficacy evaluation and safety monitoring data required in clinical trials for regulatory submission. Additionally, imaging offers insights into the drug mechanism of action (MOA) and drug effects that assist researchers in making scientific decisions. For example, in late-phase trials, medical imaging can be utilized as an imaging biomarker to improve clinical trial efficacy and reduce the time to complete a given trial.

The List of Companies - Clinical Trial Imaging Market

  1. eResearch Technology Inc
  2. Calyx Inc
  4. VIDA Diagnostics Inc
  5. WCG Clinical Inc
  6. BioTelemetry Inc
  7. Medical Metrics Inc
  8. Medpace Holdings Inc
  9. Radiant Sage LLC
  10. IXICO plc

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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