North America RNAi Therapeutics Market Drivers and Forecasts by 2027

North America RNAi Therapeutics Market Forecast to 2027 - COVID-19 Impact and Regional Analysis By Molecule Type (Small Interfering RNAs (siRNA) and MicroRNA (miRNA)); Application (Genetic Disorders, Oncology, Neurodegenerative Disorders, Cardiovascular, Respiratory Disorders, Infectious Diseases, Renal Diseases, and Other); Route of Administration (Intradermal Injections, Pulmonary Delivery, Intravenous Injections, Intraperitoneal Injections, and Others); and End User (Diagnostic Laboratories, Research and Academic Laboratories, and Hospitals)

Historic Data: 2017-2018 | Base Year: 2019 | Forecast Period: 2020-2027
  • Status : Published
  • Report Code : TIPRE00015136
  • Category : Life Sciences
  • No. of Pages : 123
  • Available Report Formats : pdf-format excel-format
  • Last update date : October 13, 2020
North America RNAi Therapeutics Market Drivers and Forecasts by 2027
Report Date: October 13, 2020   |   Report Code: TIPRE00015136 Email: sales@theinsightpartners.com

2019 Market Size

US$ 302.77 Mn

Base year value

2027 Forecast

US$ 598.60 Mn

Projected by 2027

CAGR 2020-2027

9.0 %

Growth rate

Addressable Market

US$ 3,639.61 Mn

(2020-2027)

The North America RNAi therapeutics market is expected to reach US$ 598.60 million in 2027 from US$ 302.77 million in 2019. The market is estimated to grow with a CAGR of 9.0% from 2020-2027.

Growing investments in RNAi therapies and rising prevalence of infectious diseases & chronic conditions in North Americaare the key factors driving the growth of RNAi therapeutics. However,high cost of RNAi therapies is the major factor hindering the market growth in North America.

RNAi refers to the interference RNA which is responsible to control and manipulate protein translation in the cell. These RNAi are used to silence particular genes which are responsible for diseases. Currently, the awareness about RNAi is increasing extensively due to its ability to offer target specific mechanism, leading to superior treatment outcomes. The approach is widely utilized for drug development. Increasing number of investments in RNAi therapy development coupled with growing prevalence of infectious diseases and chronic conditions are anticipated to drive the market during the forecast period.

The healthcare systems are engaged in the development and implementation of new RNA technologies to treat a wide range of diseases. A few technologies comprise genome editing technology, RNAi therapeutics, DNA-directed interference technology, and RNA-modifying enzymes. With these advantages of the implementation, the demand for RNA technologies continues to grow. This increasing preference for RNAi therapeutics is a leading factor that the number of start-ups is rising, which will, in turn, have a positive impact on activities related to the development of RNA technologies and drugs. For instance, in August 2020, RNAimmune, Inc., a spin-off start-up of Sirnaomics, Inc. raised about US$ 2.35 million through the rounds of series funding. The start-up is actively engaged in the development of RNA therapies and vaccines. Such developments in RNA technologies will reshape the RNAi therapeutics market during the forecast period.

North America has been witnessing growing number of COVID-19 cases since its outbreak. Thus, owing to the rising incidence of COVID-19 in the North America region, there is increase in demand for new therapeutic drugs. Research studies on RNAi therapy for COVID-19 in the region is likely to favor market growth. For instance, the study ‘Prospects for RNAi Therapy of COVID-19’ was conducted in University of Alberta, Edmonton, AB, Canada and was published in July 2020. Thus, growing efforts by pharmaceutical, biotech companies and academic institutes is to treat COVID-19 is likely to propel the growth of the market during the forecast period.

Mexico RNAi Therapeutics Market, Revenue and Forecast to 2027 (US$ Mn)

NORTH AMERICARNAI THERAPEUTICS MARKET SEGMENTATION

By Molecule Type

  • Small Interfering RNAs (siRNA)
  • MicroRNA (miRNA)

By Route of Administration

  • Pulmonary Delivery
  • Intravenous Injections
  • Intradermal Injections
  • Intraperitoneal Injections
  • Others

By Application

  • Oncology
  • Cardiovascular
  • Respiratory Disorders
  • Renal Diseases
  • Genetic Disorders
  • Neurodegenerative Disorders
  • Infectious Diseases
  • Others

By End User

  • Research and Academic Laboratories
  • Hospitals
  • Diagnostic Laboratories

By Country

  • US
  • Canada
  • Mexico

Company Profiles

  • Alnylam Pharmaceuticals, Inc
  • Arrowhead Pharmaceuticals, Inc
  • Quark
  • Rexahn Pharmaceuticals, Inc
  • Arbutus Biopharma

North America RNAi Therapeutics Report Scope

Report Attribute Details
Market size in 2019 US$ 302.77 Million
Market Size by 2027 US$ 598.60 Million
CAGR (2020 - 2027) 9.0%
Historical Data 2017-2018
Forecast period 2020-2027
Segments Covered By Molecule Type
  • Small Interfering RNAs
  • MicroRNA
By Application
  • Genetic Disorders
  • Oncology
  • Neurodegenerative Disorders
  • Cardiovascular
  • Respiratory Disorders
  • Infectious Diseases
  • Renal Diseases
By Route of Administration
  • Intradermal Injections
  • Pulmonary Delivery
  • Intravenous Injections
  • Intraperitoneal Injections
By End User
  • Diagnostic Laboratories
  • Research and Academic Laboratories
  • Hospitals
Regions and Countries Covered North America
  • US
  • Canada
  • Mexico
Market leaders and key company profiles
  • Alnylam Pharmaceuticals, Inc
  • Arrowhead Pharmaceuticals, Inc
  • Quark
  • Rexahn Pharmaceuticals, Inc
  • Arbutus Biopharma
Trupti Wadekar
Assistant Manager,
Market Research & Consulting

Trupti is a senior consultant with over 10 years of experience in the Healthcare sector, specializing in pharmaceuticals, biotechnology, and life-sciences markets. She holds a Bachelor’s degree in Biotechnology and an MBA with dual specialization in Marketing and Pharmaceuticals & Biotechnology, combining a strong scientific foundation with a strategic and commercial perspective. Her professional experience encompasses market research, competitive intelligence, strategic advisory, and business development, supporting clients across diverse and evolving healthcare markets.

She has worked extensively on market sizing and assessment, growth strategy, market expansion, and strategic decision-making initiatives, helping clients identify opportunities and address complex business challenges. Trupti brings strong expertise in client engagement, stakeholder management, team leadership, and translating research findings into actionable business insights. Her ability to connect scientific understanding with market dynamics and commercial strategy enables her to deliver practical, high-impact solutions aligned with client objectives.

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