Small Intestinal Bacterial Overgrowth (SIBO) Diagnostics Market to Grow at a CAGR of 4.4% to reach US$ 194,604.51 thousand from 2020 to 2028

Small Intestinal Bacterial Overgrowth (SIBO) Diagnostics Market Forecast to 2028 - COVID-19 Impact and Global Analysis By Diagnosis (Breath Testing, Small Intestine Aspirate and Fluid Culture Test, Blood Test, and Others); Type (Hydrogen-predominant SIBO, Methane-predominant SIBO, and Recurrent SIBO), and Geography

Publication Month : Mar 2021

  • Report Code : TIPRE00020544
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 174
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The SIBO diagnostics market was valued at US$ 138,324.23 thousand in 2020, and it is projected to reach US$ 194,604.51 thousand by 2028; it is expected to grow at a CAGR of 4.4% from 2021 to 2028.

Small intestinal bacterial overgrowth (SIBO) is commonly seen in the presence of one or more predisposing conditions. It varies highly based on the underlying disorders and microbiota characteristics of patients and organisms. SIBO results in gastrointestinal IBS-like symptoms, which could be asymptomatic. In worse cases, it may result in real malabsorption syndrome. The presence of SIBO is generally diagnosed with hydrogen lactulose and glucose breath tests. These tests are widely performed in every clinical setting due to their low costs, non-invasively, sufficient accuracy, and reproducibility.

The SIBO diagnostics market is segmented on the basis of diagnosis, type, and geography. Based on geography, the market is segmented into North America, Europe, Asia Pacific, Middle East & Africa, and South and Central America. The report offers insights and in-depth analysis of the SIBO diagnostics market emphasizing on various parameters such as market trends, technological advancements, market dynamics, and competitive landscape analysis of leading market players across the world. It also includes COVID-19 impact analysis across all the regions. It is estimated that the market is likely to have slower growth rate during the forecast period owing to the restricted health services and lockdown situation caused by COVID-19 pandemic.

Lucrative Regions for SIBO Diagnostics Market

Lucrative Regions for SIBO Diagnostics Market
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Market Insights

Increasing Prevalence of Irritable Bowel Syndrome (IBS) and SIBO

Irritable bowel syndrome (IBS) is the commonly diagnosed gastrointestinal disorder with abdominal pain and altered bowel habits resulting with associated symptoms such as bloating, malabsorption, and systemic symptoms. The incidences of IBS are increasing at a significant rate across the world. According to a research article, ‘Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study’ published by Elsevier Inc. in 2021, most countries have a prevalence rate of 2–6%. Countries such as Japan, China, Russia, South Africa, and the US have a prevalence rate of 2.2%, 2.3%, 5.9%, 5.9%, and 5.3%, respectively. The increasing prevalence of IBS across the world is due to the changing lifestyle and dietary habits. Small intestinal bacterial overgrowth (SIBO) is widely associated with the IBS.

Likewise, SIBO shows similar symptoms to IBS. Technological developments have now allowed the diagnosis of SIBO while diagnosing IBS. Therefore, the prevalence of SIBO is widely understood and reported worldwide. For instance, according to an article, ’Small Intestinal Bacterial Overgrowth: A Case-Based Review’ published in the Journal of Patient-Centered Research and Reviews (JPCRR) in November 2015, 30–85% of adult patients with IBS are likely to develop SIBO. Similarly, according to the recent data published in 2020 by the American College of Gastroenterology, ~78% of IBS patients are living with SBIO; hence, it is a predominantly evaluated condition. It is, therefore, estimated that the prevalence of IBS and SIBO will grow significantly in the near future, leading to the increasing diagnosis and eventual market growth.

Diagnosis-Based Insights

Based on diagnosis, the SIBO diagnostics market is segmented into breath testing, small intestine aspirate and fluid culture test, blood test, and others. In 2020, the breath testing segment held the largest share of the market, and is also expected to grow at the fastest rate in the coming years. The growth is attributed due to its advantages, such as non-invasive, patient-friendly, simplicity, and low-cost

Global SIBO Diagnostics Market, by Diagnosis – 2020 & 2028

Global SIBO Diagnostics Market, by Diagnosis – 2020 & 2028
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Type-Based Insights

Based on type, the SIBO diagnostics market is segmented into hydrogen-predominant SIBO, methane-predominant SIBO, and recurrent SIBO. In 2020, the hydrogen-predominant SIBO segment held the largest share of the market, and the same segment is expected to grow at the fastest rate during the coming years.

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Small Intestinal Bacterial Overgrowth (SIBO) Diagnostics Market: Strategic Insights

small-intestinal-bacterial-overgrowth-sibo-diagnostics-market
Market Size Value inUS$ 138,324.23 thousand in 2020
Market Size Value byUS$ 194,604.51 thousand by 2028
Growth rateCAGR of 4.4% from 2021-2028
Forecast Period2021-2028
Base Year2021
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Organic strategies such as product launch, are commonly adopted by the market players to meet the changing customer demand and maintain their improved services. For instance, in February 2020, Commonwealth Diagnostics International (CDI), Inc., announced the commercial re-launch of IBSchek, the first clinically validated biomarker blood test for diarrhea-predominant and mixed-type Irritable Bowel Syndrome (IBS-D, IBS-M) in a new at-home capillary collection kit.

By Diagnostics

  • Breath Testing
    • 14C Xylose Breath Test
    • Hydrogen Breath Tests
    • 14C Glycocholic Acid Breath Test
    • Malabsorption Tests
  • Small Intestine Aspirate and Fluid Culture Test
  • Blood Test
  • Others

By Type

  • Hydrogen-predominant SIBO
  • Methane-predominant SIBO
  • Recurrent SIBO

By Geography

  • North America

    • US
    • Canada
    • Mexico
  • Europe

    • France
    • Germany
    • Italy
    • UK
    • Spain
    • Rest of Europe
  • Asia Pacific (APAC)

    • China
    • India
    • South Korea
    • Japan
    • Australia
    • Rest of APAC
  • Middle East & Africa (MEA)

    • South Africa
    • Saudi Arabia
    • UAE
    • Rest of MEA
  • South and Central America (SCAM)

    • Brazil
    • Argentina
    • Rest of SCAM

Company Profiles

  • Genova Diagnostics
  • SIBO Diagnostics
  • Commonwealth Diagnostics International
  • Aerodiagnostics, LLC
  • SIBOTest
  • Metabolic Solutions, Inc.
  • Pivotal Diagnostics
  • DirectLabs, LLC
  • Vibrant Wellness
  • Health Associates Medical Group
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
Segment Covered

Diagnosis ; Type , and Geography

Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

Country Scope
Country Scope

Argentina, Australia, Brazil, Canada, China, France, Germany, India, Italy, Japan, Mexico, Saudi Arabia, South Africa, South Korea, Spain, United Arab Emirates, United Kingdom, United States

Frequently Asked Questions


What is small intestinal bacterial overgrowth?

Small intestinal bacterial growth (SIBO) is commonly seen in the presence of one or more predisposing conditions. It varies highly based on the underlying disorders and microbiota characteristics of patients and organisms. SIBO results in gastrointestinal IBS-like symptoms, which could be asymptomatic. In worse cases, it may result in real malabsorption syndrome. The presence of SIBO is generally diagnosed with hydrogen lactulose and glucose breath tests. These tests are widely performed in every clinical setting due to their low costs, non-invasively, sufficient accuracy, and reproducibility.

What are the driving factors for the SIBO diagnostic market across the globe?

Key factors that are driving growth of the market are increasing incidence of IBS and SIBO and advantages offered by breath tests. However, limitation of diagnostics is a key factor restraining the market growth.

What is the cost of SIBO diagnostics?

The cost is based on the type of diagnostics test. For instance, the hydrogen breath test is much cheaper than any other test. The cost of the test ranges from US$ 145–US$ 400. Likewise, the cost of endoscopy is ~US$ 135.

The List of Companies - Small Intestinal Bacterial Overgrowth (SIBO) Diagnostics Market

  1. Genova Diagnostics
  2. SIBO Diagnostics
  3. Commonwealth Diagnostics International
  4. Aerodiagnostics, LLC
  5. SIBOTest
  6. Metabolic Solutions, Inc.
  7. Pivotal Diagnostics
  8. DirectLabs, LLC
  9. Vibrant Wellness
  10. Health Associates Medical Group

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

  1. Data Collection and Secondary Research:

As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

  1. Primary Research:

The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

A typical research interview fulfils the following functions:

  • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
  • Validates and strengthens in-house secondary research findings
  • Develops the analysis team’s expertise and market understanding

Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

  • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
  • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

  • 3.1 Macro-Economic Factor Analysis:

We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

  • 3.2 Country Level Data:

Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

  • 3.3 Company Profile:

The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • 3.4 Developing Base Number:

Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

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