Ultrasound-Enhancing Agents Market Outlook 2031

Ultrasound-Enhancing Agents Market Size and Forecast (2021 - 2031), Global and Regional Share, Trend, and Growth Opportunity Analysis Report Coverage: By Type (First Generation and Second Generation), Application (Abdominal Imaging, Cardiovascular Imaging, Urinary Tract Imaging, and Others), End User (Hospitals, Diagnostic and Imaging Centers, and Others), and Geography (North America, Europe, Asia Pacific, Middle East & Africa, and South & Central America)

  • Report Code : TIPRE00039130
  • Category : Medical Device
  • Status : Data Released
  • No. of Pages : 150
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The ultrasound-enhancing agents market forecast is derived on the basis of findings from various secondary and primary research sources. According to The Insight Partners' estimates, the market was valued at US$ 756.61 million in 2023 and is expected to reach US$ 2,511.52 million by 2031; it is estimated to record a CAGR of 16.2% during 2023–2031.

Ultrasound-enhancing agents, also known as ultrasound contrast agents (UCA), are injected to enhance the resolution of images of the organs during an ultrasound scan. These agents consist of suspensions of gas-filled microbubbles smaller than red blood cells and reflect ultrasound signals as they flow through the microcirculation in the blood vessels. They are expelled from the body via urine or bowel movements, within minutes after injection. These agents do not contain any dyes and are considered safe as they pose no known risk of nephrotoxicity.

Factors Driving Ultrasound-Enhancing Agents Market Growth

Ultrasound imaging is currently the first step in estimating the severity of oncological diseases and cardiovascular conditions, paving the way for accurate assessment and diagnosis through further investigation. It is widely used for real-time imaging of body parts for the detection of abnormalities due to the portability, low cost, safety, and diagnostic capabilities of the system. In addition, using contrast agents has significantly improved the sensitivity and specificity of ultrasound for detecting earlier stages of diseases, thus opening up new possibilities for cellular and molecular research in this field. The surging prevalence of chronic diseases such as cancer, kidney diseases, and liver disorders propels the demand for early diagnoses for better management. Their diagnoses necessitate advanced imaging modalities for early detection and health monitoring among diagnosed patients. Ultrasound-enhancing agents enable enhanced visualization of tumors, lesions, and abnormal tissue growth. According to an article published in radiopaedia.org in September 2023, Sonazoid, a contrast agent used in ultrasound imaging, enhances the liver's contrast in the postvascular phase, which can help detect liver tumors, especially those without Kupffer cell metastases. Sonazoid also helps differentiate between regenerative and dysplastic nodules from early-phase hepatocellular carcinomas in a cirrhotic liver. Therefore, the rising adoption of UCAs in diagnostic imaging boosts the ultrasound-enhancing agents market size.

According to an article published in October 2021 by the International Contrast Ultrasound Society (ICUS), 57 original research studies focused solely on pediatric patients, including 4,518 children who underwent 4,906 intravenous contrast-enhanced ultrasound examinations as of August 2021. Additionally, comprehensive protocols developed to evaluate clinical safety demonstrated the highly favorable safety profile of UCAs when used intravenously, intravesically, and through other intracavitary procedures.

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Ultrasound-Enhancing Agents Market: Strategic Insights

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Report Segmentation and Scope:

The "Global Ultrasound-Enhancing Agents Market Analysis to 2031" is a specialized and in-depth study focusing on the global market dynamics to help identify the key driving factors, future trends, and lucrative opportunities that would, in turn, aid in identifying major revenue pockets. The report aims to provide an overview of the market with detailed market segmentation by type, application, and end user. The geographic scope of the ultrasound-enhancing agents market report entails North America (US, Canada, and Mexico), Europe (Spain, UK, Germany, France, Italy, and Rest of Europe), Asia Pacific (South Korea, China, India, Japan, Australia, and Rest of Asia Pacific), Middle East & Africa (South Africa, Saudi Arabia, UAE, and Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America).

Segmental Analysis:

The ultrasound-enhancing agents market, by type, is bifurcated into the first generation and second generation. The second generation segment held a larger market share in 2023. It is projected to register a higher CAGR from 2023 to 2031.

The market, by application, is segmented into abdominal imaging, cardiovascular imaging, urinary tract imaging, and others. The abdominal imaging segment accounted for the largest ultrasound-enhancing agents market share in 2023. The cardiovascular imaging segment is projected to register the highest CAGR from 2023 to 2031.

Based on end user, the market is segmented into hospitals, diagnostic and imaging centers, and others. The hospitals segment held the largest share of the market in 2023. Further, the diagnostic and imaging centers segment is expected to register the highest CAGR from 2023 to 2031.

Regional Outlook:

North America held the largest ultrasound-enhancing agents market share in 2023. The US dominated the market in this region, in terms of share, followed by Canada. Market growth in the US is attributed to factors such as the presence of major players, including Lantheus Holdings Inc. and GE Healthcare. These companies are increasingly focusing on joint ventures and research collaborations. For instance, GE Healthcare focuses on expanding its product portfolio by launching innovative products and entering strategic partnerships with competitors. In addition, an upsurge in the number of ultrasound procedures due to favorable reimbursement policies supports the ultrasound-enhancing agents market growth in the US.

Industry Developments and Future Opportunities:

As per company press releases, a few initiatives taken by key players operating in the global ultrasound-enhancing agents market are listed below:

  • In March 2024, Samsung Medison and Bracco Imaging endorsed a Memorandum of Understanding (MoU) agreement to develop a new area for diagnostic ultrasound devices and contrast agents at the European Congress of Radiology (ECR) 2024, held between February 28 to March 3 in Vienna, Austria. Two companies are considering collaborating to develop high-frequency and super-resolution imaging protocols for diagnosis. The collaboration would also include marketing activities, healthcare providers’ education, and exploration of ultrasound-targeted contrast-enhanced drug delivery technologies with pharmaceutical agents.
  • In April 2023, GE HealthCare launched Pixxoscan (Gadobutrol). It is a macrocyclic, gadolinium-based contrast agent (GBCA) for nonionic magnetic resonance imaging. The product was added to the company’s MRI contrast media portfolio, which includes Claiscan (macrocyclic gadoteric acid) and Rapiscan (used in stress cardiac MR to aid diagnosis of coronary artery disease).

Competitive Landscape and Key Companies:

Lantheus Holdings Inc.; GE Healthcare; Solstice Pharmaceuticals B.V.; FUJIFILM VisualSonics, Inc.; Bracco Diagnostics Inc.; Bayer AG; and Vesselon are among the prominent companies profiled in the ultrasound-enhancing agents market report. These companies focus on new technologies, existing product advancements, and geographic expansions to meet the growing consumer demand worldwide.

Ultrasound-Enhancing Agents Market Report Scope

Report Attribute Details
Market size in
Market Size by
Global CAGR ()
Historical Data
Forecast period
Regions and Countries Covered
Market leaders and key company profiles
    • Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
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    Report Coverage
    Report Coverage

    Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

    Segment Covered
    Segment Covered

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    to segments covered.

    Regional Scope
    Regional Scope

    North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

    Country Scope
    Country Scope

    This text is related
    to country scope.

    Frequently Asked Questions


    What is ultrasound-enhancing agent?

    Ultrasound-enhancing agents, also known as ultrasound contrast agents (UCA), are injected to enhance the resolution of images of the organs during an ultrasound scan. These agents consist of suspensions of gas-filled microbubbles smaller than red blood cells and reflect ultrasound signals as they flow through the microcirculation in the blood vessels. They are expelled from the body via urine or bowel movements, within minutes after injection. These agents do not contain any dyes and are considered safe as they pose no known risk of nephrotoxicity.

    What factors drive the ultrasound-enhancing agents market?

    Key factors driving the ultrasound-enhancing agents informatics growth are the increasing investments in the R&D of new drug molecules by pharmaceutical companies and the growing adoption of computational and information tools for ultrasound-enhancing agents and development.

    What was the estimated ultrasound-enhancing agents market size in 2023?

    The ultrasound-enhancing agents informatics was valued at US$ 756.61 million in 2023.

    What are the growth estimates for the ultrasound-enhancing agents market till 2031?

    The ultrasound-enhancing agents market is expected to be valued at US$ 2,511.52 million in 2031.

    Which type segment dominates the ultrasound-enhancing agents market?

    The ultrasound-enhancing agents market is bifurcated into the first generation and second generation. The second generation segment held a larger market share in 2023. It is projected to register a higher CAGR from 2023 to 2031.

    Who are the major players in the ultrasound-enhancing agents market?

    The ultrasound-enhancing agents market majorly consists of the players, including Lantheus Holdings Inc.; GE Healthcare; Solstice Pharmaceuticals B.V.; FUJIFILM VisualSonics, Inc.; Bracco Diagnostics Inc.; Bayer AG; and Vesselon.

    The List of Companies - Ultrasound-Enhancing Agents Market

    1. Lantheus Holdings Inc.
    2. GE Healthcare
    3. Solstice Pharmaceuticals BV
    4. FUJIFILM VisualSonics, Inc.
    5. Bracco Diagnostics Inc.
    6. Bayer AG
    7. Vesselon

    The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

    1. Data Collection and Secondary Research:

    As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

    Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.

    1. Primary Research:

    The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.

    For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.

    A typical research interview fulfils the following functions:

    • Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
    • Validates and strengthens in-house secondary research findings
    • Develops the analysis team’s expertise and market understanding

    Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:

    • Industry participants: VPs, business development managers, market intelligence managers and national sales managers
    • Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.

    Below is the breakup of our primary respondents by company, designation, and region:

    Research Methodology

    Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

    1. Data Analysis:

    Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

    • 3.1 Macro-Economic Factor Analysis:

    We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.

    • 3.2 Country Level Data:

    Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.

    • 3.3 Company Profile:

    The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

    • 3.4 Developing Base Number:

    Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.

    1. Data Triangulation and Final Review:

    The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

    We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.

    We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.

    Your data will never be shared with third parties, however, we may send you information from time to time about our products that may be of interest to you. By submitting your details, you agree to be contacted by us. You may contact us at any time to opt-out.

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