[研究报告]DNA下一代测序市场规模预计将从2017年的48.985亿美元增至2025年的227.169亿美元;预计2018-2025年复合年增长率为21.7%。
下一代测序也称为高通量测序。 NGS 能够对 DNA 样本中的碱基对进行快速测序。 NGS 正在推动药物发现应用,并实现个性化医疗、遗传疾病和临床诊断的未来。此外,下一代测序(NGS)是一种大规模并行测序技术,可以建立整个基因组中的核苷酸顺序,具有可扩展性、超高通量和快速的特点。由于DNA预测序包括为后续测序反应准备样品,因此它是整个测序方案中最重要的过程之一。在全球医疗保健领域,NGS正在稳步融入临床实验室分析、测试和疾病诊断。在药物基因组学领域,NGS 已被广泛应用于加速药物发现过程。
DNA 下一代测序市场的增长归因于不断增加的全球癌症病例数量、研究不断增加、研究机构和市场参与者之间的合作不断增加,以及 DNA 下一代测序的应用不断增加以及测序技术的进步。然而,熟练专业人员的缺乏预计将严重影响 DNA 下一代测序市场的整体增长。
DNA 下一代测序市场的利润丰厚的区域
市场洞察
测序价格的下降和测序方法的技术进步推动DNA下一代测序市场
近年来,下一代测序技术测序价格大幅下降。 2000年,人类基因组测序耗资37亿美元,历时13年才完成。然而,近几年的成本已降至2006年的1000万美元,并在2012年进一步下降,而且过程所需的天数也更少。 Illumina 和 Roche 等主要 DNA 下一代测序市场参与者推出了具有成本效益且测序过程所需时间更少的突破性技术。
此外,技术的进步分子生物学领域同样增强了测序程序。过去几年,许多行业参与者提出了创新的 NGS 技术。例如,Pacific Biosciences 的 Sequel 和 Oxford Nanopore 的 PromethION。此外,主导市场的三种先进 NSG 系统包括 Roche GS FLX (454)、Illumina HiSeq 2000 (Solexa) 和 AB SOLiD (Agencourt)。
进一步修改和自动化这一过程不断增加测序数据,并更有效地管理时间,从而使研究人员能够实现人类基因组计划的重要里程碑。 NGS 使基于序列的基因表达分析成为一种“数字化”分析。模拟技术的替代方案。基因组测序的进步使得测序变得简单而准确。这些技术进步可能会在不久的将来扩大 DNA 下一代测序市场规模。
基于产品的见解
全球 DNA 下一代测序一代测序市场根据产品分为平台、服务和消耗品。该平台部分进一步细分为 HiSeq 系列、MiSeq 系列、SOLiD、Ion Torrent、Pacbio Rs II 和 Sequel Systems 等。此外,服务部分又细分为测序服务和数据管理和分析服务。此外,耗材部分又细分为样品耗材制备和其他NGS耗材。 2017年,耗材细分市场在DNA下一代测序市场的产品细分市场中占有较大份额,预计在预测期内也将遵循类似的趋势。最近的 NGS 平台采用了一种新的测序方法,称为单分子测序 (SMS),该方法不需要事先扩增 DNA,从而避免了 PCR 相关的错误读取或对重复区域的扩增偏差。在过去五年中,下一代测序(NGS)已经从研究转向临床应用。至少有 14 个国家发起了对大量人口进行测序的举措,预计到 2025 年,全球将有超过 6000 万人进行基因组测序。
应用-基于洞察
全球 DNA 下一代测序市场根据应用分为诊断、药物发现、精准医疗和其他应用。诊断领域在 2017 年占据最大份额,预计在未来五到六年内将出现显着增长。在诊断基因组护理中使用下一代测序 (NGS) 技术需要精确性和准确性。 NGS 技术使用经济高效的测序,从全基因组测序中获取患者的基因组信息,以执行临床行动。下一代测序最终将取代传统技术来诊断各种遗传性疾病。现在可以在一次测试中解决大量基因问题,而不是逐个基因的方法。
基于最终用户的见解
全球市场根据最终用户分为学术市场和商业市场。研究机构、制药及生物技术公司、医院和诊所和其他最终用户。学术和研究机构部门预计将在预测期内实现最高增长。该序列有助于科学家找到特定 DNA 片段中携带的遗传信息类型。例如,科学家可以使用序列信息来确定哪些 DNA 片段包含基因,哪些片段携带调控指令,从而打开或关闭基因。位于马里兰州罗克维尔的基因组研究所 (TIGR) 引入了基于随机或鸟枪测序的自动化工业化方法,并导致发表了 337 个新的人类基因和 48 个来自其他生物体的同源基因
< p>战略洞察
产品发布和批准是公司扩大全球足迹和产品组合的常用策略。此外,市场参与者注重合作伙伴战略来扩大客户群,这反过来又使他们能够在全球范围内保持自己的品牌声誉。随着市场参与者开发新的创新产品,市场份额预计将不断扩大。相关市场的一些市场参与者包括 THERMO FISHER SCIENTIFIC INC.;照明公司;凯杰公司;北京基因组研究所;珀金埃尔默公司; F.霍夫曼-拉罗氏有限公司;安捷伦科技;欧洲金融科学公司;牛津纳米孔技术有限公司;和 Macrogen 公司。
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
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to segments covered.
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
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Frequently Asked Questions
The growth of the global DNA next generation sequencing market is attributed to the increases in cancer prevalence, technological development and decreasing price of sequencing. Owing to factors like advances within the field of genetic science, development in several ways and methods for sequencing, there's a notable decline within the price of sequencing.
As per forecast report, the market value of DNA next generation sequencing market in 2025 will be US$ 22,716.9 Million.
The DNA next generation sequencing market is growing at CAGR of 21.7% from 2018-2025.
Major market players such as Illumina and Roche have introduced breakthrough technologies that have enabled in the cost and time reduction in the sequencing.
The List of Companies
1. Illumina, Inc.
2. Thermo Fisher
3. Qiagen N.V.
4. Beijing Genomics Institute
5. PerkinElmer, Inc.
6. Hoffman-La Roche Ltd.
7. Agilent Technologies
8. Eurofins Scientific
9. Oxford Nanopore Technologies Ltd.
10. Macrogen Inc.
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organization are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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