基于(关键地区、市场参与者、规模和份额)的病毒载体和质粒 DNA 制造市场 - 到 2031 年的预测

  • Report Code : TIPRE00003074
  • Category : Biotechnology
  • Status : Published
  • No. of Pages : 140
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[研究报告]病毒载体和质粒DNA制造市场规模预计将从2019年的4.594亿美元增长到2027年的22.477亿美元;进一步估计,从 2020 年到 2027 年,复合年增长率将达到 22.1%。

分析师观点:

对基因治疗的需求不断增长,以及用于治疗开发的基因编辑技术的进步各种慢性疾病、病毒感染等的选择正在推动病毒载体和质粒 DNA 制造市场的增长。此外,研究活动的增加以及制药和制药领域的投资不断增加。生物技术行业随后的有利监管环境预计将预测市场增长。此外,先进计算技术的整合预计将在不久的将来扩大病毒载体和质粒DNA制造的应用领域,从而推动市场增长。

市场概况:

病毒载体是用于基因传递和操作的工具。它是经过改造的病毒,经过工程改造,可以携带特定基因并将其传递到细胞中。病毒载体通常用于基因编辑应用的基因治疗,因为它们可以有效地将遗传物质传递到靶细胞中。质粒载体是一小段圆形 DNA,与细胞中的染色体 DNA 分开。质粒可以独立复制,常见于细菌中。在研究中,质粒经常被用作载体,将基因引入细胞以用于各种目的,例如蛋白质生产或基因工程。病毒载体和质粒 DNA 都是研究中基因传递和操作的重要工具,使研究人员能够了解潜在的应用。

战略见解

市场趋势:

先进计算技术的集成

人工智能、数据科学、自然语言处理等革命性技术的出现预计将在预测期内重塑医疗保健技术的未来。然而,基因疗法为疾病治疗提供了创新的解决方案,其实施面临一些技术挑战。例如,基因替换错误可能会导致 DNA 发生有害突变,从而导致严重的健康问题。为了实现程序的高精度,智能算法可以提供一种重要的方法。此外,大多数参与者都在从事新技术的研发,这将满足对现代技术日益增长的需求。例如,2019 年 3 月,Oxford Biomedica 与微软达成战略合作,以改进基因疗法。此外,2020 年 5 月,Dyno Therapeutics 宣布拟投资约 20 亿美元,用于设计基于人工智能的基因疗法。此类事件为先进计算技术的整合提供了巨大的机遇,最终将在未来几年重新定义基因疗法的概念。

细分分析:

基于应用,病毒载体和质粒 DNA 制造市场分为癌症、遗传性疾病、病毒感染等。癌症细分市场在 2019 年占据最大市场份额,预计该细分市场在预测期内复合年增长率最高,达到 22.6%。病毒载体和非病毒载体都有其应用,并且正在研究其在癌症或肿瘤学中的预防和治疗应用。基于病毒载体的抗癌剂免疫或抗癌基因递送是一些关键研究领域,已取得稳步进展。此外,政府批准用于治疗急性淋巴细胞白血病(ALL)和大B细胞淋巴瘤的基于慢病毒载体的CAR-T细胞疗法也引起了用户的广泛关注。病毒载体和非病毒载体导致基于癌症的先进疗法管道项目显着增加。例如,大约三分之二的基因治疗研究集中在肿瘤学上。上述因素导致癌症相对于其他疾病领域占据主导地位。根据产品,全球病毒载体和质粒DNA制造市场分为病毒载体和非病毒载体。 2019年,病毒载体细分市场占据最大的市场份额,预计该细分市场在未来几年将以最快的复合年增长率增长。

区域分析:

基于地理位置全球病毒载体和质粒 DNA 制造市场细分为北美、欧洲、亚太地区、中东和非洲。非洲、南美和非洲中美洲。北美拥有最大的病毒载体和质粒 DNA 制造市场份额,紧随其后的是欧洲。 2019年,美国在北美病毒载体和质粒DNA制造市场中占据最大份额。美国市场的增长主要是由于人们对基因治疗益处的认识不断增强、研发活动不断增加以及对先进技术的需求不断增长。治疗慢性病和病毒感染的治疗解决方案。

此外,由于基因疗法的日益采用,对病毒载体的需求不断增加,预计也将在预测期间推动美国病毒载体和质粒 DNA 制造市场的增长时期。此外,由于需求不断增长,市场主要参与者都专注于扩大其病毒载体生产能力。例如,2020年5月,赛默飞世尔科技公司宣布计划扩大病毒载体生产能力。据公司估计,新工厂将于 2022 年投入运营。此外,2020 年 4 月,默克宣布计划在美国开设一家新的病毒载体制造工厂。该公司已为此拟议扩张投资约 1.126 亿美元。

在加拿大,由于医疗保健系统的发展和现代细胞技术的迅速普及,病毒载体和质粒 DNA 制造市场预计将增长。相关技术。另一方面,在墨西哥,由于人们对病毒载体和质粒 DNA 带来的好处的认识不断增强,预计病毒载体和质粒 DNA 制造市场可能会经历增长机会。

主要参与者分析:

病毒载体和质粒 DNA 制造市场主要由 Brammer Bio、Sanofi、Cardinal Health Inc、FUJIFILM Diosynth Biotechnologies、Cell and Gene Therapy Catapult、Cobra Biologics、FinVector、Kaneka Eurogentec SA 等参与者组成、MassBiologics、Spark Therapeutics 和 Uniqure 等。在病毒载体和质粒 DNA 制造市场的参与者中,赛诺菲 (Sanofi) 和 FUJIFILM Diosynth Biotechnologies 由于其有机和无机活性而成为前两名参与者。

最新动态: 

病毒载体和质粒DNA制造市场的公司高度采用并购等无机和有机策略。下面列出了最近的一些关键市场动态:

  • 2023 年 3 月,Sartorius 以 24 亿欧元(26 亿美元)收购了法国公司 Polyplus。该交易为赛多利斯提供了核酸输送方面的更多专业知识,包括转染试剂和质粒 DNA 设计,所有这些都是生产用于构建细胞和基因疗法的病毒载体的关键要素。
  • 2021 年 7 月Thermo Fisher Scientific Inc. 在加利福尼亚州卡尔斯巴德开设了一家新的 cGMP 质粒 DNA 制造工厂,使其能够满足对基于质粒 DNA 的疗法和基于 mRNA 的重要疫苗快速增长的需求。
  • 2021 年 3 月今年2月,瓦克从韩国首尔Helixmith Co Ltd和首尔Medivate Partners LLC手中收购了制药合同制造商Genopis Inc. 100%的股份。相关协议签署后,于二月底成功完成收购,现在,此次收购的新名称为:Wacker Biotech US Inc.
Report Coverage
Report Coverage

Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends

Segment Covered
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Regional Scope
Regional Scope

North America, Europe, Asia Pacific, Middle East & Africa, South & Central America

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Frequently Asked Questions


Who are the major players in the viral vector & plasmid DNA manufacturing market?

The viral vector & plasmid DNA manufacturing market majorly consists of the players such as Brammer Bio, Sanofi, Cardinal Health Inc., FUJIFILM Diosynth Biotechnologies. Cell and Gene Therapy Catapult, Cobra Biologics, FinVector, Kaneka Eurogentec S.A., MassBiologics, Spark Therapeutics, and Uniqure among others.

What are the driving factors for the viral vector & plasmid DNA manufacturing market across the globe?

Driving factor such as growing awareness of gene therapy and increasing prevalence of genetic disorders and infectious diseases across the world are expected to upsurge the market growth. In addition, growth in the global healthcare market is likely to have a positive impact on the market in the coming years.

What is viral vector & plasmid DNA manufacturing?

Gene delivery into target cells can be performed using several different vectors. These are broadly classified into viral and non-viral vectors, both of which present benefits and risks. Viral vectors are tools that are commonly used by molecular biologists to deliver genetic material into cells. The non-viral vectors are Naked DNA, particle-based, and chemical-based.

The List of Companies - Portable and Wearable Dialysis Devices Market

  1. Brammer Bio
  2. Sanofi
  3. FUJIFILM Diosynth Biotechnologies
  4. Cell and Gene Therapy Catapult
  5. Cobra Biologics
  6. FinVector
  7. Kaneka Eurogentec S.A.
  8. MassBiologics
  9. Spark Therapeutics
  10. Uniqure

 

The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.

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As a market research and consulting firm operating from a decade, we have published and advised several client across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.

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Below is the breakup of our primary respondents by company, designation, and region:

Research Methodology

Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.

  1. Data Analysis:

Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.

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The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.

  • Developing Base Number:

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  1. Data Triangulation and Final Review:

The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.

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