Netherton Syndrome Market to Grow at a CAGR of 20.3% to reach US$ 74.31 Million from 2020 to 2027

    Netherton Syndrome Market Forecast to 2027 - COVID-19 Impact and Global Analysis by Therapy (Keratolytic Agents, Oral and Topical Steroids and Retinoids, Topical Calcineurin Inhibitors, Radiation Therapy, and Biological Therapy), and Geography

    Publication Month: Sep 2020 | Report Code: TIPRE00013771 | No. of Pages: 76 | Category: Pharmaceuticals | Status: Published

    The Netherton syndrome market was valued at US$ 19.57 million in 2019 and is projected to reach US$ 74.31 million 2027; it is expected to grow at a CAGR of 20.3%from 2020 to 2027.
    Netherton syndrome is a rare disorder characterized by trichorrhexis invaginata, atopic diathesis, and ichthyosiform erythroderma. The trichorrhexis invaginata indicates short and brittle hair, atopic diathesis represents susceptibility to allergy problems while ichthyosiform erythroderma encompasses red, inflamed, scaly skin. Netherton syndrome is hereditary as it is an autosomal recessive trait. The disease is majorly caused due to mutations associated with SPINK5 gene. In some cases, although there is no family history of the disease, the syndrome is revealed even when two healthy parents that carry the mutated recessive gene have a child, which receives both copies of the recessive gene. The Netherton syndrome market is witnessing huge growth on the back of the increasing awareness regarding Netherton syndrome and growing number of product introductions. Moreover, rising number of clinical trials and robust pipeline of products act as significant opportunities for the future growth of the market players. However, the risk of adverse reactions associated with the Netherton syndrome treatment drugs restrains the growth of the market.

    Lucrative Regions in Global Netherton Syndrome Market
    Lucrative Regions in Global Netherton Syndrome Market

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    Market Insights

    Increasing Number of Awareness Campaigns for Netherton Syndrome to Drive the Growth

    Netherton syndrome is an autosomal recessive rare skin-related disorder that affects the hair, skin and immune system. The disease usually affects newborns in which, the skin is usually red and scaly as well as leak fluids in some cases. The patients suffering with this condition are usually unaware of the treatment options available as well as do not have easy access and ample information regarding the care to be taken. Awareness campaigns are impactful in terms of enabling timely and accurate diagnosis. Thus, various medical and social organizations are working towards spreading awareness and helping the patients suffering with Netherton syndrome around the world.

    Foundation for Ichthyosis& Related Skin Types (FIRST) in collaboration with National Health Council (NHC) developed an organization that aims to improve lives and seek cures for the patients affected by ichthyosis and related skin types. The organization provides accurate and timely information regarding Netherton syndrome and ichthyosis that helps the patients to meet social, medical and educational needs of the disease community. Furthermore, the Ichthyosis Support Group (ISG) aims to protect and preserve the health and relieves patients affected by ichthyosis and other associated condition. The ISG provides information pack, distributes bulletins and newsletters organize children’s residential camps and others.

    Thus, the awareness campaigns and programs for informing the patients and other people regarding Netherton’s syndrome are expected to augment the growth of the market over the coming years.

    Therapy-Based Insights

    Based on therapy, the global Netherton syndrome market is segmented into keratolytic agents, oral and topical steroids and retinoids, topical calcineurin inhibitors, biological therapies, and radiation therapies. In 2019, the keratolytic agents segment held the largest share of the market. Growth of this segmental market is attributed to the increasing product launches and robust existing product pipeline. In addition, strategic activities by service providers such as collaborations, mergers and acquisitions, and expansions to expedite drug timeline are further accelerating the growth of the market. However, the biological therapy segment is projected to register the highest CAGR in the global Netherton syndrome market during 2020–2027.

    Netherton Syndrome Market, by Therapy – 2019 and 2027
    Netherton Syndrome Market, by Therapy – 2019 and 2027

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    Strategic Insights

    Product launches and research collaborations are the commonly adopted strategies by companies to expand their footprint worldwide and meet the growing consumer demand. The Netherton syndrome market players adopted the strategy of product innovations to cater to changing customer demand across the world, which also permits them to maintain their brand name globally.

    Netherton Syndrome Market – by Therapy

    • Keratolytic Agents
    • Oral and Topical Steroids and Retinoid
    • Topical Calcineurin Inhibitors
    • Radiation Therapies
    • Biological Therapies

    Netherton Syndrome Market – by Geography

    • North America
      • US
    • Europe
      • France
      • Germany
      • Italy
      • UK
      • Spain
    • Asia Pacific(APAC)
      • Japan

    Company Profiles

    • Lifemax Laboratories, Inc.
    • Azitra, Inc.
    • Sixera Pharma Ab
    • Dermelix Biotherapeutics
    • Matrisys Bioscience
    • Quoin Pharmaceuticals Ltd.
    • Krystal Biotech, Inc.

    1. Introduction

    1.1 Scope of the Study

    1.2 The Insight Partners Research Report Guidance

    1.3 Market Segmentation

    1.3.1 Global Netherton Syndrome Market – By Epidemiology

    1.3.2 Global Netherton Syndrome Market – By Therapy

    1.3.3 Global Netherton Syndrome market – By Geography

    2. Netherton Syndrome Market – Key Takeaways

    3. Research Methodology

    3.1 Coverage

    3.2 Secondary Research

    3.3 Primary Research

    3.4 Expert Opinions

    4. Global Netherton Syndrome Market – Disease Background And Overview

    4.1 Introduction

    4.2 Causes and Pathophysiology

    4.3 Ages

    4.4 Risk Factors

    4.5 Diagnosis

    4.6 Epidemiology

    5. Netherton Syndrome Market– Key Market Dynamics

    5.1 Market Drivers

    5.1.1 Increasing Number of Awareness Campaigns

    5.1.2 Increasing Drug Launches and Robust Pipeline

    5.2 Market Restraint

    5.2.1 Side-Effects Associated with Netherton Syndrome Drugs

    5.3 Market Opportunity

    5.3.1 Growth Opportunities in Developing Economies

    5.4 Impact Analysis of Drivers and Restraints

    6. Netherton Syndrome Market – Global Analysis

    6.1 Global Netherton Syndrome Market Revenue Forecast and Analysis

    6.2 Global Netherton Syndrome Market, By Geography - Forecast and Analysis

    6.3 Market Positioning of Key Players

    7. Netherton Syndrome Market Analysis – By Epidemiology

    7.1 Overview

    7.2 Prevalent Cases

    7.2.1 Overview

    7.3 Diagnosed Cases

    7.3.1 Overview

    7.4 Gender-Specific Cases

    7.4.1 Overview

    7.5 Drug-Treatable Cases

    7.5.1 Overview

    8. Netherton Syndrome Market Analysis – By Therapy

    8.1 Overview

    8.2 Netherton Syndrome Market Revenue Share, by Therapy (2019 and 2027)

    8.3 Keratolytic Agents

    8.3.1 Overview

    8.3.2 Keratolytic Agents: Netherton Syndrome Market – Revenue and Forecast to 2027 (US$ Million)

    8.4 Biological Therapies

    8.4.1 Overview

    8.4.2 Biological Therapies: Netherton Syndrome Market – Revenue and Forecast to 2027 (US$ Million)

    8.5 Oral and Topical Steroids and Retinoids

    8.5.1 Overview

    8.5.2 Oral and Topical Steroids and Retinoids: Netherton Syndrome Market – Revenue and Forecast to 2027 (US$ Million)

    8.6 Topical Calcineurin Inhibitors

    8.6.1 Overview

    8.6.2 Topical Calcineurin Inhibitors: Netherton Syndrome Market – Revenue and Forecast to 2027 (US$ Million)

    8.7 Radiation Therapy

    8.7.1 Overview

    8.7.2 Radiation Therapy: Netherton Syndrome Market – Revenue and Forecast to 2027 (US$ Million)

    9. Netherton Syndrome Market– Geographic Analysis

    9.1 North America: Netherton Syndrome Market

    9.1.1 Overview

    9.1.1.1 US: Netherton Syndrome Market– Revenue and Forecast to 2027 (USD Million)

    9.1.1.1.1 US: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.1.1.1.2 US: Netherton Syndrome Market , Epidemiology Forecast 2017–2030

    9.1.1.1.3 US: Netherton Syndrome Market , by Therapy, 2018–2027 (USD Million)

    9.2 Europe: Netherton Syndrome Market

    9.2.1 Overview

    9.2.2 Europe: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.3 Europe: Netherton Syndrome Market, by Therapy, 2018–2027 (USD Million)

    9.2.4 Europe: Netherton Syndrome Market, by Country, 2019 & 2027 (%)

    9.2.4.1 Germany: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.1.1 Germany: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.1.2 Germany: Netherton Syndrome Market, Epidemiology Forecast, 2017–2030

    9.2.4.1.3 Germany: Netherton Syndrome Market, by Therapy, 2018–2027 (USD Million)

    9.2.4.2 France: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.2.1 France: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.2.2 France: Netherton Syndrome Market, Epidemiology Forecast, 2017–2030

    9.2.4.2.3 France: Netherton Syndrome Market, by Therapy, 2018–2027 (USD Million)

    9.2.4.3 UK: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.3.1 UK: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.3.2 UK: Netherton Syndrome Market, Epidemiology Forecast, 2017–2030

    9.2.4.3.3 UK: Netherton Syndrome Market, by Therapy, 2018–2027 (USD Million)

    9.2.4.4 Italy: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.4.1 Italy: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.4.2 Italy: Netherton Syndrome Market, Epidemiology Forecast, 2017–2030

    9.2.4.4.3 Italy: Netherton Syndrome Market, by Therapy, 2018–2027 (USD Million)

    9.2.4.5 Spain: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.5.1 Spain: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.2.4.5.2 Spain: Netherton Syndrome Market, Epidemiology Forecast, 2017–2030

    9.2.4.5.3 Spain: Netherton Syndrome Market, by Therapy, 2018–2027 (USD Million)

    9.3 Asia Pacific: Netherton Syndrome Market

    9.3.1 Overview

    9.3.1.1 Japan: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.3.1.1.1 Japan: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    9.3.1.1.2 Japan: Netherton Syndrome Market, Epidemiology Forecast, 2017–2030

    9.3.1.1.3 Japan: Netherton Syndrome Market, by Therapy, 2018–2027 (USD Million)

    10. Netherton Syndrome Market – Treatment and Emerging Therapies

    10.1 Treatment Paradigm

    10.2 Emerging Therapies

    10.3 Clinical Trials by Phase

    10.4 Attribute Analysis (Marketed and Upcoming Therapies)

    11. Company Profiles

    11.1 LIFEMAX LABORATORIES

    11.1.1 Key Facts

    11.1.2 Business Description

    11.1.3 Products and Services

    11.1.4 Financial Overview

    11.1.5 SWOT Analysis

    11.1.6 Key Developments

    11.2 Azitra Inc

    11.2.1 Key Facts

    11.2.2 Business Description

    11.2.3 Products and Services

    11.2.4 Financial Overview

    11.2.5 SWOT Analysis

    11.2.6 Key Developments

    11.3 Sixera Pharma (Gozinto )

    11.3.1 Key Facts

    11.3.2 Business Description

    11.3.3 Products and Services

    11.3.4 Financial Overview

    11.3.5 SWOT Analysis

    11.3.6 Key Developments

    11.4 Dermelix Biotherapeutics

    11.4.1 Key Facts

    11.4.2 Business Description

    11.4.3 Products and Services

    11.4.4 Financial Overview

    11.4.5 SWOT Analysis

    11.4.6 Key Developments

    11.5 MATRISYS BIOSCIENCE

    11.5.1 Key Facts

    11.5.2 Business Description

    11.5.3 Products and Services

    11.5.4 Financial Overview

    11.5.5 SWOT Analysis

    11.5.6 Key Developments

    11.6 Quoin Pharmaceuticals Ltd.

    11.6.1 Key Facts

    11.6.2 Business Description

    11.6.3 Products and Services

    11.6.4 Financial Overview

    11.6.5 SWOT Analysis

    11.6.6 Key Developments

    11.7 Krystal Biotech

    11.7.1 Key Facts

    11.7.2 Business Description

    11.7.3 Products and Services

    11.7.4 Financial Overview

    11.7.5 SWOT Analysis

    11.7.6 Key Developments

    12. Appendix

    12.1 About The Insight Partners

    12.2 Glossary of Terms

    LIST OF TABLES

    Table 1. US Netherton Syndrome Market , Epidemiology Forecast 2017-2030

    Table 2. US Netherton Syndrome Market , by Therapy– Revenue and Forecast to 2027 (USD Million)

    Table 3. Europe Netherton Syndrome Market, by Therapy, – Revenue and Forecast to 2027 (USD Million)

    Table 4. Germany Netherton Syndrome Market, Epidemiology Forecast, 2017-2030

    Table 5. Germany Netherton Syndrome Market, by Therapy, – Revenue and Forecast to 2027 (USD Million)

    Table 6. France Netherton Syndrome Market, Epidemiology Forecast, 2017-2030

    Table 7. France Netherton Syndrome Market, by Therapy, – Revenue and Forecast to 2027 (USD Million)

    Table 8. UK Netherton Syndrome Market, Epidemiology Forecast, 2017-2030

    Table 9. UK Netherton Syndrome Market, by Therapy, – Revenue and Forecast to 2027 (USD Million)

    Table 10. Italy Netherton Syndrome Market, Epidemiology Forecast, 2017-2030

    Table 11. Italy Netherton Syndrome Market, by Therapy, – Revenue and Forecast to 2027 (USD Million)

    Table 12. Spain Netherton Syndrome Market, Epidemiology Forecast, 2017-2030

    Table 13. Spain Netherton Syndrome Market, by Therapy, – Revenue and Forecast to 2027 (USD Million)

    Table 14. Japan Netherton Syndrome Market, Epidemiology Forecast, 2017-2030

    Table 15. Japan Netherton Syndrome Market, by Therapy, – Revenue and Forecast to 2027 (USD Million)

    Table 16. Glossary of Terms, Netherton Syndrome Market

    LIST OF FIGURES

    Figure 1. Netherton Syndrome Market Segmentation

    Figure 2. Netherton Syndrome Market Segmentation, By Region

    Figure 3. Netherton Syndrome Market Overview

    Figure 4. Keratolytic Agent Segment Held Largest Share of Netherton Syndrome Market

    Figure 5. North America to Show Significant Growth During Forecast Period

    Figure 6. Netherton Syndrome Market, by Geography (US$ Million)

    Figure 7. Global Netherton Syndrome Market – Leading Country Markets (US$ Million)

    Figure 8. Global Netherton Syndrome Market, Industry Landscape

    Figure 9. Netherton Syndrome Market Impact Analysis of Driver and Restraints

    Figure 10. Global Netherton Syndrome Market – Revenue Forecast And Analysis – 2019- 2027

    Figure 11. Market Positioning Of Key Players In Global Netherton Syndrome Market

    Figure 12. Netherton Syndrome Market Revenue Share, by Therapy (2019 and 2027)

    Figure 13. Keratolytic Agents: Netherton Syndrome Market– Revenue and Forecast to 2027 (US$ Million)

    Figure 14. Biological Therapies: Netherton Syndrome Market– Revenue and Forecast to 2027 (US$ Million)

    Figure 15. Oral and Topical Steroids and Retinoids: Netherton Syndrome Market– Revenue and Forecast to 2027 (US$ Million)

    Figure 16. Topical Calcineurin Inhibitors: Netherton Syndrome Market– Revenue and Forecast to 2027 (US$ Million)

    Figure 17. North America: Netherton Syndrome Market, by Key Country – Revenue (2019) (USD Million)

    Figure 18. US: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    Figure 19. Europe: Netherton Syndrome Market , by Key Country – Revenue (2019) (USD Million)

    Figure 20. Europe Netherton Syndrome Market Revenue and Forecast to 2027 (USD Million)

    Figure 21. Europe: Netherton Syndrome Market, by Country, 2019 & 2027 (%)

    Figure 22. Germany: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    Figure 23. France: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    Figure 24. UK: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    Figure 25. Italy: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    Figure 26. Spain: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    Figure 27. Asia Pacific: Netherton Syndrome Market, by Key Country – Revenue (2019) (USD Million)

    Figure 28. Japan: Netherton Syndrome Market – Revenue and Forecast to 2027 (USD Million)

    The List of Companies - Netherton Syndrome Market

    1. Lifemax Laboratories, Inc.
    2. Azitra, Inc.
    3. Sixera Pharma Ab
    4. Dermelix Biotherapeutics
    5. Matrisys Bioscience
    6. Quoin Pharmaceuticals Ltd.
    7. Krystal Biotech, Inc
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    • Highlights key business priorities in order to assist companies to realign their business strategies.
    • The key findings and recommendations highlight crucial progressive industry trends in the global Netherton syndrome market, thereby allowing players across the value chain to develop effective long-term strategies.
    • Develop/modify business expansion plans by using substantial growth offering developed and emerging markets.
    • Scrutinize in-depth global market trends and outlook coupled with the factors driving the market, as well as those hindering it.
    • Enhance the decision-making process by understanding the strategies that underpin security interest with respect to client products, segmentation, pricing and distribution.
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    Frequently Asked Questions

    Netherton syndrome is a rare genetic disorder that presents the three following characteristics: Ichthyosiform erythroderma, a red, inflamed, scaly skin. Trichorrhexis invaginata – short, brittle, lustreless hair, Atopic diathesis – predisposition to allergy problems. Netherton syndrome is inherited as an autosomal recessive trait disease. The NS condition is caused by mutations in the SPINK5 gene that is found on the chromosome. In some cases, there is no family history of the disease. NS is revealed when two unaffected parents (recessive) and both are carriers of the mutated recessive gene have a child who receives both copies of the recessive gene.
    The factors that are driving growth of the market are increasing number of Netherton syndrome awareness campaigns and growing number of product launches with robust pipeline. Moreover, strategic activities by the manufacturers are offering lucrative opportunities for the growth of the market.
    The Netherton syndrome market majorly consists of the players such as Lifemax Laboratories, Inc., Azitra, Inc., Sixera Pharma Ab, Dermelix Biotherapeutics, Matrisys Bioscience, Quoin Pharmaceuticals Ltd., and Krystal Biotech, Inc. among others.

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