North America Genome Editing Market to Reach US$ 4,148.1 Mn at CAGR of 17.2% in 2025 | The Insight Partners

North America Genome Editing Market to 2025 - Regional Analysis and Forecasts by Technology (TALENS, CRISPR, Zinc Finger Nucleases (ZFNs), Antisense RNA and Others), Application (Genetic Engineering, Cell Line Engineering and Others) End User (Biotechnology & Pharmaceutical Companies, Contract Research Organizations (CROs), and Academic & Government Research Institutes), and Country

Publication Month: Apr 2019 | Report Code: TIPRE00003907 | No. of Pages: 155 | Category: Biotechnology | Status: Published

The North America genome editing market accounted to US$ 1,234.5 Mn in 2017 and is expected to grow at a CAGR of 17.2% during the forecast period 2018 – 2025, to account to US$ 4,148.1 Mn by 2025.

The Asia Pacific genome editing market is expected to grow at highest rate during the forecast period owing to increasing investments by the governments of the respective countries in the region. In addition, the rise in the development and research for the genome editing along with the clinical trials are expected to fuel the market growth in Asia Pacific region.         

 

Exhibit: Lucrative Regional Markets

Market Insights

Rise in the Production of Genetically Modified Crops

The genome editing has proved itself to be the most promising way of feeding the fast growing population across the world. The changes in the climatic conditions due to the global warming and others conditions such as droughts floods are witnessed more across the world. Therefore the feeding the rising population is question among the people across the world. Due to the genome editing the concerns are being reduced to a great level, the two types of the genetically modified crops are widely grown. Firstly, these crops are altered in a ways that they are not affected by the herbicide glyphosate. Secondly, crops are produced to protect themselves from the insecticides.

The advantages of the genetically modified crops includes diseases resistance, improvement of the photosynthesis, improvement of the nutrition, and more. The genetic modification helps to enhance the productivity without hampering the health of the crops. In addition, for the genetically modified crops the limited resources are required and it require less or no pesticides for its growth. The time required for the growth of the genetically modified crops is less, therefore these are highly preferred crops in the western world. The demand for the genetically modified crops is rising in the eastern region due to the benefits offered by these crops.

According to the International Service For The Acquisition Of Agri-Biotech Applications (ISAAA), 2017 statistics, 19 developing countries have planted 53% which is approximately to 100.6 million hectares of the global biotech hectares, whereas the 5 industrial countries have took the 47% which is near about 89.2 million hectares share. The trend of growing genetically modified crop is expected to grow in the coming future. Moreover, the data reveled that among the 24 countries that planted biotech crops in 2016, among them 18 countries are considered as biotech mega-countries. These countries grew approximately 50, 000 hectares of biotech crops. The US remained as top producer of biotech crops across the world. The country planted 75 million hectares in 2017, which covered 40% of the global biotech crop plantings. Similarly, Brazil positioned itself on the second position, with 50.2 million hectares which covered 26% of the global output.

 

Limitations in Genome Editing

Rapid advances in biotechnology such as gene editing is likely to raise some regulatory challenges, in turn, government struggle to keep pace. According to the Worldwide Threat Assessment of the US Intelligence Community, the US National Academies of Science have organized a variety of domestic and international meetings about issued reports on the potential promises and downsides of gene editing in the US. Gene editing included in the Worldwide Threat Assessment reports, which was submitted in 2016 and 2017. In spite of the scientific and policy interest, In the US, there were no any published study about Crispr technology that how gene editing technologies are developing within and across specific country contexts. Moreover, gene editing research involves human embryos faces varied regulatory obstacles in certain countries. For instance, In Canada, human germline editing is now banned. Certainly, it is criminalized under the 2004 Assisted Human Reproduction Act, and punishable by fines of 500,000 Canadian dollars or up to 10 years of jail time. Recently, the Canadian Institutes of Health Research (the Canadian equivalent of the US National Institutes of Health) has challenged the law with respect to gene editing and has called for human germline gene editing to be decriminalized and legalized.

The researches in genome editing conducted by countries with different regulatory or ethical standards. On the other hand, the risk of the creation of potentially harmful biological agents or products has probably increased in Western countries. With the low cost, and hastened pace of development of this dual-use technology, the market is expected to grow in the coming years. But, it’s considered or unintentional misuse lead to far-reaching economic and national security implications. Due to increasing advances in genome editing, the groups of biologists are required in the US to put a question about unregulated editing of the human germline that possibly create inheritable genetic changes.

However, researchers in the country, are continually trying to encounter challenges such as, technical limitations that are essential in available genome editing systems, to achieve the desired outcome of their genome modifications.

 

Emerging Markets For Precision and Regenerative Medicines

The invention of the CRISPR has led to various applications of the gene editing in living organisms, the change of the expression in a living cell is the most attracting one. The application of gene editing is gene therapy which is used for the treating various genetic diseases. The market is mostly acquired by the gene therapy however, there are wider scope for the precision or personalized medicine in the coming years. In addition, the use of CRISPR is been used for cancer treatments which are into the process of clinical trials, and is expected that the number of clinical trials will increase in the coming near future.

In addition, it expected that CRISPR can be utilized for the precision medicine and regenerative medicines. The researcher from the MIT and Harvard's Broad Institute have found that gene have ability of the therapeutic effects in neurodegenerative diseases such as Alzheimer's as well as multiple sclerosis, kidney disease, certain cancers and others. Also the genome editing is rapidly developed for several applications and is widely used in biomedical researches. The researches includes creation of disease models with desired genetic mutations, screening in a high-throughput manner for drug resistance genes, and making appropriate editions to genes in vivo for disease treatment. The applications of the genome editing have facilitated the development of precision medicine research and it is expected that in the coming future genome editing would lead to the precision medicine. The genome editing provides opportunities introduce to a known disease-specific mutation in order to study the pathophysiology which will lead to various companies to invent precision and regenerative medicine in the coming future and also the research for it will enhance the growth of the genome editing market in the forecast period.

 

Technology Insights

The genome editing market by technology is segmented as, transcription activator-like effector nucleases (TALENS), clustered regularly interspaced short palindromic repeats (CRISPR), zinc finger nucleases (ZFNs), antisense RNA and others. In 2017, the CRISPR segment held a largest market share of 53.6% of the genome editing market. This segment is also expected to dominate the market in 2025 owing to the simple, fast and accurate property of the CRISPR. Moreover, the TALENs segment is anticipated to witness the significant growth rate of 17.1% during the forecast period, 2018 to 2025 owing to the properties provided by the TALENs the market for it is expected to rise in the coming near future.

 

Application Insights

The North America genome editing market on the basis of application is segmented into genetic engineering, cell line engineering and others. The cell line engineering segment is anticipated to grow at a CAGR of 18.0% during the forecast period. Moreover, the genetic engineering segment is expected to grow at the significant rate during the coming years owing to its sub segments such as animal genetic engineering and plant genetic engineering that are being carried out extensively.

 

End User Insights

The North America genome editing market on the basis of end user is segmented into biotechnology & pharmaceutical companies, academic & government research organizations, and contract research organization. In 2017, biotechnology & pharmaceutical companies segment held the largest share of 61.2% of the end user market, and is expected to grow at the fastest rate during the coming years owing to the advantages of the CRISPR, the companies have enhanced their research and development for the drug discoveries that can treat various diseases. Hence, the market is likely to propel in the coming years.

 

Exhibit: Genome Editing Market, by End User
  

 

 

Strategic Insights

Strategic acquisition and product launches were observed as the most adopted strategy in North America genome editing industry. Few of the recent product launch and product approval are listed below:

 

2018: Thermo Fisher Scientific announced the acquisition of IntegenX. IntegenX has been developing rapid DNA testing technology for human identification for use in forensics and law enforcement. The company in 2015, has launched RapidHIT System, which is the first-generation STR-based human identification system that is also compatible with Thermo Fisher's STR kits.

2017: Integrated DNA Technologies announced the product launch of variants of the first Cas9 enzyme. These are used for extensive reduction off-target effects in CRISPR genome editing and does not compromise on-target activity. The Alt-R S.p. HiFi Cas9 Nuclease 3NLS enzyme is a recombinant S. pyogenes Cas9 mutant improvises the specificity and also maintenance a high editing efficiency similar to wild-type Cas9.

2016: GenScript announced the launch of its new service CRISPR based Yeast Genome Editing Service. The service utilizes the λ Red-CRISPR/Cas9 technology.

 

NORTH AMERICA GENOME EDITING – MARKET SEGMENTATION

 

By Technology

  • TALENS
  • CRISPR
  • Zinc Finger Nucleases (ZFNs)
  • Others

 

By Application

  • Genetic Engineering
    • Animal Genetic Engineering
    • Plant Genetic Engineering
  • Cell Line Engineering
  • Others

 

By End User

  • Biotechnology & Pharmaceutical Companies
  • Contract Research Organizations (CROs)
  • Academic & Government Research Institutes

 

By Geography

•   North America

  • U.S.
  • Canada
  • Mexico

 

Company Profiles

  • Transposagen Biopharmaceuticals, Inc.
  • Integrated DNA Technologies, Inc.
  • Thermo Fisher Scientific Inc.
  • GenScript
  • Lonza
  • Horizon Discovery Group plc
  • Sangamo Therapeutics, Inc.
  • New England Biolabs
  • Editas Medicine
  • Merck KGaA

PART 1.       iNTRODUCTION

1.1            Scope of the Study

1.2            The Insight Partners Research Report Guidance

PART 2.       North America GENOME EDITING TESTING Market – Key takeaways

PART 3.       North America genome editing market – market landscape

3.1            overview

3.2            market segmentation

3.2.1          North America Genome Editing Market – By Technology

3.2.2          North America Genome Editing Market – By Application

3.2.3          North America Genome Editing Market – By End User

3.2.4          North America Genome Editing Market – By Country

3.3            PEST Analysis

PART 4.       North America genome editing market- Key Market Dynamics

4.1            Key Market Drivers

4.1.1          Rise in the Production of Genetically Modified Crops

4.1.2          Rising Prevalence of The Genetic Diseases

4.2            Key Market Restraints

4.2.1          Stringent Regulatory Framework

4.2.2          Limitations in Genome Editing

4.3            Key Market Opportunities

4.3.1          Emerging Markets For Precision and Regenerative Medicines

4.4            future Trends

4.4.1          Rising Demand for CRISPR Cas9 Technology

4.5            Impact analysis

PART 5.       Genome Editing market – North America Analysis

5.1            North America GENOME EDITING market Revenue Forecasts and Analysis

5.2            Market positioning

5.3            PERFORMANCE OF KEY PLAYERS

5.4            expert opinions

PART 6.       North America GENOME EDITING market Analysis – By Technology

6.1            Overview

6.2            NORTH AMERICA GENOME EDITING MARKET, BY technology, 2017 & 2025 (%)

6.3            North America GENOME EDITING market Revenue And Forecasts to 2025, By Technology (US$ Mn)

6.4            transcription activator-like effector nucleases (TALENS) Market

6.4.1          Overview

6.4.2          North America Transcription Activator-Like Effector Nucleases (TALENS) Market Revenue and Forecasts to 2025 (US$ Mn)

6.5            clustered regularly interspaced short palindromic repeats (CRISPR) Market

6.5.1          Overview

6.5.2          North America Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Market Revenue and Forecasts to 2025 (US$ Mn)

6.6            zinc finger nucleases (ZFNs) Market

6.6.1          Overview

6.6.2          North America Zinc Finger Nucleases (ZFNs) Market Revenue and Forecasts to 2025 (US$ Mn)

6.7            Antisense RNA Market

6.7.1          Overview

6.7.2          North America Antisense RNA Market Revenue and Forecasts to 2025 (US$ Mn)

6.8            Others Market

6.8.1          Overview

6.8.2          North America Others Market Revenue and Forecasts to 2025 (US$ Mn)

PART 7.       North America genome editing market Analysis – By Application

7.1            Overview

7.2            NORTH AMERICA GENOME EDITING MARKET, BY Application, 2017 & 2025 (%)

7.3            North America GENOME EDITING market Revenue And Forecasts to 2025, By Application (US$ Mn)

7.4            Genetic Engineering Market

7.4.1          Overview

7.4.2          North America Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

7.4.3          Animal Genetic Engineering Market

7.4.3.1      Overview

7.4.3.2      North America Animal Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

7.4.4          Plant Genetic Engineering Market

7.4.4.1      Overview

7.4.4.2      North America Plant Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

7.5            cell line engineering Market

7.5.1          Overview

7.5.2          North America Cell Line Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

7.6            Others Market

7.6.1          Overview

7.6.2          North America Others Market Revenue and Forecasts to 2025 (US$ Mn)

PART 8.       North America genome editing market Analysis – By End User

8.1            Overview

8.2            NORTH AMERICA GENOME EDITING MARKET, BY end user, 2017 & 2025 (%)

8.3            North America GENOME EDITING market Revenue And Forecasts to 2025, By end user (US$ Mn)

8.4            Biotechnology & pharmaceutical Companies Market

8.4.1          Overview

8.4.2          North America Biotechnology & Pharmaceutical Companies Market Revenue and Forecasts to 2025 (US$ Mn)

8.5            ACADEMIC & GOVERNMENT RESEARCH ORGANIzATIONS Market

8.5.1          Overview

8.5.2          North America Drug Manufacturers Market Revenue and Forecasts to 2025 (US$ Mn)

8.6            Contract Research organization Market

8.6.1          Overview

8.6.2          North America Research Institutes Market Revenue and Forecasts to 2025 (US$ Mn)

PART 9.       North America genome editing market Revenue and Forecasts to 2025

9.1            Overview

9.2            North America Genome Editing testing market Revenue and Forecasts to 2025 (US$ Mn)

9.3            North America Genome editing Market Revenue And Forecasts to 2025, By technology (US$ Mn)

9.4            North America Genome editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

9.4.1          North America Genetic Engineering Market Revenue And Forecasts to 2025, By Type (US$ Mn)

9.5            North America Genome editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

9.6            North America Genome editing Market Revenue And Forecasts to 2025, By Country (%)

9.7            US Genome Editing testing market Revenue and Forecasts to 2025 (US$ Mn)

9.7.1          US Genome Editing testing market Revenue and Forecasts to 2025 (US$ Mn)

9.8            US Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.8.1          US Genome Editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.8.2          US Genome Editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

9.8.3          US Genome Editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

9.8.3.1      US Genetic Engineering Market Revenue And Forecasts to 2025, By Type (US$ Mn)

9.8.4          US Genome Editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

9.9            Canada Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.9.1          Canada Genome Editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.9.2          Canada Genome Editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

9.9.3          Canada Genome Editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

9.9.3.1      Canada Genetic Engineering Market Revenue And Forecasts to 2025, By Type (US$ Mn)

9.9.4          Canada Genome Editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

9.10         Mexico Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.10.1       Mexico Genome Editing Market Revenue and Forecasts to 2025 (US$ Mn)

9.10.2       Mexico Genome Editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

9.10.3       Mexico Genome Editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

9.10.3.1    Mexico Genetic Engineering Market Revenue And Forecasts to 2025, By Type (US$ Mn)

9.10.4       Mexico Genome Editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

PART 10.    Genome Editing Market–Key company profiles

10.1         Thermo Fisher Scientific Inc.

10.1.1       Key Facts

10.1.2       Business Description

10.1.3       Financial Overview

10.1.4       Product Portfolio

10.1.5       SWOT Analysis

10.1.6       Key Developments

10.2         Integrated DNA Technologies, Inc.

10.2.1       Key Facts

10.2.2       Business Description

10.2.3       Financial Overview

10.2.4       Product Portfolio

10.2.5       SWOT Analysis

10.2.6       Key Developments

10.3         Merck Kgaa

10.3.1       Key Facts

10.3.2       Business Description

10.3.3       Financial Overview

10.3.4       Product Portfolio

10.3.5       SWOT ANALYSIS

10.3.6       KEY DEVELOPMENTS

10.4         Lonza

10.4.1       Key Facts

10.4.2       Business Description

10.4.3       Financial Overview

10.4.4       Product Portfolio

10.4.5       SWOT Analysis

10.4.6       Key Developments

10.5         New England Biolabs

10.5.1       Key Facts

10.5.2       Business Description

10.5.3       Financial Overview

10.5.4       Product Portfolio

10.5.5       SWOT Analysis

10.5.6       Key Developments

10.6         GenScript

10.6.1       Key Facts

10.6.2       Business Description

10.6.3       Financial Overview

10.6.4       Product Portfolio

10.6.5       SWOT Analysis

10.6.6       Key Developments

10.7         Transposagen Biopharmaceuticals, inc.

10.7.1       Key Facts

10.7.2       Business Description

10.7.3       Financial Overview

10.7.4       Product/ Services Portfolio

10.7.5       SWOT Analysis

10.7.6       Key Developments

10.8         Horizon Discovery Group Plc

10.8.1       Key Facts

10.8.2       Business Description

10.8.3       Financial Overview

10.8.4       Product/ Services Portfolio

10.8.5       SWOT Analysis

10.8.6       Key Developments

10.9         Sangamo Therapeutics, Inc.

10.9.1       Key Facts

10.9.2       Business Description

10.9.3       Financial Overview

10.9.4       Product Portfolio

10.9.5       SWOT Analysis

10.9.6       Key Developments

10.10      Editas MEdicine

10.10.1     Key Facts

10.10.2     Business Description

10.10.3     Financial Overview

10.10.4     Service Portfolio

10.10.5     SWOT Analysis

10.10.6     Key Developments

PART 11.    Appendix

11.1         About The Insight Partners

11.2         Glossary of Terms

11.3         Methodology

11.3.1       Coverage

11.3.2       Secondary Research

11.3.3       Primary Research


list of tables

TABLE 1.           North America GENOME EDITING market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 2.           North America GENOME EDITING market Revenue And Forecasts to 2025, By Application (US$ Mn)

TABLE 3.           North America GENOME EDITING market Revenue And Forecasts to 2025, By end user (US$ Mn)

TABLE 4.           North America Genome editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 5.           North America Genome editing Market Revenue And Forecasts to 2025, By application (US$ Mn)

TABLE 6.           North America genetic engineering Market Revenue And Forecasts to 2025, By type (US$ Mn)

TABLE 7.           North America Genome editing Market Revenue And Forecasts to 2025, By end user (US$ Mn)

TABLE 8.           US Genome editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 9.           US Genome editing Market Revenue And Forecasts to 2025, By application (US$ Mn)

TABLE 10.        US genetic engineering Market Revenue And Forecasts to 2025, By type (US$ Mn)

TABLE 11.        US Genome editing Market Revenue And Forecasts to 2025, By End user (US$ Mn)

TABLE 12.        Canada Genome editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 13.        Canada Genome editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

TABLE 14.        Canada genetic engineering Market Revenue And Forecasts to 2025, By type (US$ Mn)

TABLE 15.        Canada Genome editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

TABLE 16.        Mexico Genome editing Market Revenue And Forecasts to 2025, By Technology (US$ Mn)

TABLE 17.        Mexico Genome editing Market Revenue And Forecasts to 2025, By Application (US$ Mn)

TABLE 18.        Mexico genetic engineering Market Revenue And Forecasts to 2025, By type (US$ Mn)

TABLE 19.        Mexico Genome editing Market Revenue And Forecasts to 2025, By End User (US$ Mn)

TABLE 20.        Glossary of Terms, GENOME EDITING market


list of figures

FIGURE 1.        US genome editing market, Revenue (US$ Mn), By COuntry 2018 & 2025

FIGURE 2.        north America genome editing Market By Type, Market Share (%), 2017

FIGURE 3.        north America genome editing Market By services, Market Share (%), 2017

FIGURE 4.        North America genome editing Market By end user, Market Share (%), 2017

FIGURE 5.        genome editing market Segmentation

FIGURE 6.        North America PEST Analysis

FIGURE 7.        genome editing market impact analysis of drivers & Restraints

FIGURE 8.        North America GENOME EDITING market – Revenue Forecasts and Analysis – 2017- 2025

FIGURE 9.        North America GENOME EDITING market, By technology, 2017 & 2025 (%)

FIGURE 10.     North America transcription activator-like effector nucleases (TALENS) Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 11.     North America Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 12.     North America Zinc Finger Nucleases (ZFNs) Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 13.     North America Antisense RNA Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 14.     North America Others Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 15.     North America GENOME EDITING market By Application, 2017 & 2025 (%)

FIGURE 16.     North America Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 17.     North America Animal Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 18.     North America Plant Genetic Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 19.     North America Cell Line Engineering Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 20.     North America Others Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 21.     North America GENOME EDITING market By end user, 2017 & 2025 (%)

FIGURE 22.     North America Biotechnology & Pharmaceutical Companies Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 23.     North America drug manufacturers Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 24.     North America Research Institutes Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 25.     North America genome editing market REVENUE overview, by Country, 2017 (US$ MN)

FIGURE 26.     North America Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 27.     North America Genome editing Market Revenue And Forecasts to 2025, By Country (%)

FIGURE 28.     US genome editing market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 29.     US genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 30.     Canada Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

FIGURE 31.     Mexico Genome editing Market Revenue and Forecasts to 2025 (US$ Mn)

 

 

 

The List of Companies

1. Transposagen Biopharmaceuticals, Inc.
2. Integrated DNA Technologies, Inc.
3. Thermo Fisher Scientific Inc.
4. GenScript
5. Lonza
6. Horizon Discovery Group plc
7. Sangamo Therapeutics, Inc.
8. New England Biolabs
9. Editas Medicine
10. Merck KGaA
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