CRISPR and Cas gene market size is projected to grow from US$ 2.78 billion in 2022 to US$ 15.10 billion by 2030; the market is estimated to record a CAGR of 23.6% during 2022–2030.
Market Insights and Analyst View:
The report includes growth prospects owing to the current CRISPR and Cas gene market trends and their foreseeable impact during the forecast period. Factors such as the increasing prevalence of cancer and genetic diseases, and the growing adoption of CRISPR-based screens with improved genomic targets propel the market growth. However, off-target effects and ethical concerns associated with CRISPR technology impede the growth of the market. In the coming years, increasing research funding for genomic studies and efforts made to demonstrate the effectiveness of CRISPR in genomics are likely to bring new trends into the market.
The CRISPR technology is useful in identifying mutations in many tumors. They recognize modified proteins that are specific to human tumors. Therefore, personalized treatments enabled by CRISPR technology for chronic diseases such as cancer drive the market expansion. In addition, factors such as investments by biotech companies in new treatments; increased genomic research and development; and the rising burden of cancer, bloodborne diseases, and so on are facilitating the CRISPR and Cas gene market growth. However, the use of CRISPR in drug development and therapeutic procedures is limited by its possibility of going off target, which limits the market progress.
Growth Drivers:
Increasing Prevalence of Cancer and Genetic Disorders Drives Market Growth
According to the American Cancer Society, the estimated number of people diagnosed with cancer in the US was 1.9 million in 2022. Additionally, a paper published in November 2022 in the Nature Journal states that researchers can use CRISPR gene editing to alter immune cells to recognize altered proteins specific to a person's tumors. These cells can then be safely delivered into the body to locate their targets for elimination, thus aiding in a personalized treatment option against cancer and other chronic diseases.
The increasing prevalence of genetic disorders further drives the need for gene editing technologies such as CRISPR and Cas genes. According to the World Health Organization (WHO), millions of people worldwide are affected by genetic disorders, as almost 1 in 20 live births has a genetic disorder. The CRISPR/Cas system can be used as a potential tool in developing treatment approaches for various genetic diseases, including sickle cell anemia, cystic fibrosis, and Huntington's disease. Many clinical trials are ongoing for testing the safety and effectiveness of CRISPR-based therapies in genetic disorders. Thus, the increasing demand for CRISPR and Cas gene technologies in various therapeutic areas to treat cancer and other chronic and genetic diseases fuels the CRISPR and Cas gene market growth.
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CRISPR and Cas Gene Market: Strategic Insights
Market Size Value in US$ 2.78 billion in 2022 Market Size Value by US$ 15.10 billion by 2030 Growth rate CAGR of 23.6% from 2022 to 2030 Forecast Period 2022-2030 Base Year 2022
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CRISPR and Cas Gene Market: Strategic Insights
| Market Size Value in | US$ 2.78 billion in 2022 |
| Market Size Value by | US$ 15.10 billion by 2030 |
| Growth rate | CAGR of 23.6% from 2022 to 2030 |
| Forecast Period | 2022-2030 |
| Base Year | 2022 |
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Report Segmentation and Scope:
The CRISPR and Cas gene market analysis has been carried out by considering the following segments: product & service, application, and end user.
- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
Segmental Analysis:
By application, the CRISPR and Cas gene market is bifurcated into biomedical and agriculture. The biomedical segment held a larger market share in 2022. The same segment is anticipated to register a higher CAGR of 23.8% during the forecast period. CRISPR gene editing technologies are being used in different areas of life sciences. Well-established delivery methods and nanocarrier usage have further improved the effectiveness and specificity of this technology. Various studies have been conducted to explain the use of this method to modify human somatic cell and pluripotent stem cell genomes. Some companies also offer commercial kits and services to assist researchers through the use of CRISPR gene editing techniques.
Improving agricultural production through innovative breeding technologies has resulted in better access to nutrient-dense foods worldwide. In June 2019, researchers at Cold Spring Harbor Laboratory implemented CRISPR/Cas9 technology for inducing mutations in the flowering suppressor of tomatoes, resulting in rapid flowering and improved compact growth of tomatoes, ultimately, leading to early yield.
CRISPR and Cas Gene Market, by Product & Service – 2022 and 2030
- Sample PDF showcases the content structure and the nature of the information with qualitative and quantitative analysis.
The CRISPR and Cas gene market, by product & service, is divided into products and services. The products segment held a larger market share in 2022. The same segment is expected to register a higher CAGR of 23.9% during the forecast period. Numerous cutting-edge technologies such as CRISPR and Cas gene editing kits have been developed and introduced to meet the growing demand. An upsurge in the share of these kits in the overall market is attributed to the availability of improved single products that can achieve different goals, including simple gene knockouts, reduced off-target cutting, selective genome cleavage, genome engineering, and higher specificity. Increased investments in research and development related to gene editing would further benefit the overall CRISPR and Cas Gene market during the forecast period.
The market, by end user, is categorized into biotechnology and pharmaceutical companies, academics and government research institutes, and contract research organizations (CROs) and CDMOs. The biotechnology and pharmaceutical companies segment held the largest CRISPR and Cas gene market share in 2022. It is anticipated to register the highest CAGR of 24.2% during the forecast period. Biotechnology and pharmaceutical companies use these technologies to quickly identify and validate new therapeutic targets as well as to create better biological models of human diseases in less time. They also use gene modification techniques for commercial purposes.
Regional Analysis:
The scope of the CRISPR and Cas gene market report entails North America, Europe, Asia Pacific, South & Central America, and the Middle East & Africa. In 2022, North America held the largest CRISPR and Cas gene market share. The market growth in this region is driven by flourishing research and development operations in the biopharmaceuticals industry, as well as the involvement of several pharmaceutical companies in the development of novel therapeutics. In May 2020, Merck KGaA received approval from the US Food and Drug Administration (FDA) for two CRISPR Cas9-driven gene editing patents. In addition, various federal initiatives in the US and Canada support agricultural biotechnology research and the commercial release of CRISPR-based plant products. Many pharmaceutical and seed companies have invested in growth strategies such as partnerships, acquisitions, and collaborations to advance the pharmaceutical market and crop growth, respectively, which would further bolster the demand for CRISPR technology in these industries.
Europe is expected to occupy the second-largest share in the global CRISPR and Cas gene market. European authorities have introduced stricter regulations for new technologies, including gene therapy and genetically modified organisms. Despite strict regulations, the region is rapidly adopting CRISPR techniques in biomedical, medical, agricultural, and therapeutic applications.
Asia Pacific is expected to witness the fastest CAGR of 24.3% in the market during the forecast period. The market growth in this region is ascribed to increasing government investments in research and development to develop novel treatments. Companies and research institutes in China are conducting research on genome editing for drug development, and they have recently announced several clinical trials to seek approval for the use of CRISPR in cancer treatment. In March 2021, Setsuro Tech, a Japanese biotech company, received a patent for CRISPR-Cas9 technology developed by Dublin-based ERS Genomics. Such initiatives are expected to propel the adoption of CRISPR technology in Asia Pacific in the future.
Industry Developments and Future Opportunities:
The CRISPR and Cas gene market forecast can help stakeholders in this marketplace plan their growth strategies. A few of the strategic developments by leading market players are listed below:
- In February 2023, Ensoma acquired Twelve Bio ApS to further develop its in vivo engineered cell medicines portfolio. Twelve Bio is a company engaged in exploring therapeutic applications of next-generation CRISPR-Cas drugs.
- In December 2022, a researcher from the University of California started off with a clinical trial entitled “Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease” to evaluate hematopoietic stem cell transplantation (HSCT) using CRISPR/Cas9-edited red blood cells—known as CRISPR_SCD001 Drug Product).
- In November 2022, researchers at the Massachusetts Institute of Technology developed a CRISPR-based PASTE tool that inserts large DNA sequences into desired cell locations. The technique can be potentially used in the treatment of various genetic diseases.
- In November 2021, Health Canada approved the clinical trial application submitted by CRISPR Therapeutics and ViaCyte for VCTX210, a CRISPR-engineered stem cell therapy for treating type 1 diabetes.
Competitive Landscape and Key Companies:
CRISPR Therapeutics; Thermo Fisher Scientific; Merck; GenScript; Qiagen; Takara Bio Inc.; Brain Biotech AG; Intellia Therapeutics, Inc.; New England Biolabs; and Editas Medicine, Inc. are among the prominent companies profiled in the CRISPR and Cas gene market report. These companies focus on developing new technologies, upgrading existing products, and expanding their geographic presence to meet the growing consumer demand worldwide.
Report Coverage
Revenue forecast, Company Analysis, Industry landscape, Growth factors, and Trends
Segment Covered
Product & Service, Application, End User, and Geography
Regional Scope
North America, Europe, Asia Pacific, Middle East & Africa, South & Central America
Country Scope
This text is related
to country scope.
Frequently Asked Questions
The global CRISPR and Cas gene market, based on product & service is segmented into products and services. The products segment held a larger market share in 2022. The same segment is expected to register a higher CAGR of 23.9% during the forecast period. Based on application, the CRISPR and Cas gene market is segmented into biomedical and agriculture. The biomedical segment held a larger market share in 2022. The same segment is anticipated to register a higher CAGR of 23.8% during 2022–2030. In terms of end user, the CRISPR and Cas gene market is segmented into biotechnology and pharmaceutical companies, academics and government research institutes, and contract research organizations (CROs) and CDMOs. The biotechnology and pharmaceutical companies segment held the largest CRISPR and Cas gene market share in 2022. It is anticipated to register the highest CAGR of 24.2% during the forecast period.
The CRISPR and Cas gene market was valued at US$ 2.78 billion in 2022.
The CRISPR and Cas gene market is expected to be valued at US$ 15.10 billion in 2030.
The CRISPR and Cas gene market majorly consists of the players such as CRISPR Therapeutics; Thermo Fisher Scientific; Merck; GenScript; Qiagen; Takara Bio Inc.; Brain Biotech AG; Intellia Therapeutics, Inc.; New England Biolabs; and Editas Medicine, Inc.
The CRISPR technology is useful in identifying mutations in many tumors. They recognize modified proteins that are specific to human tumors. The technology can safely be utilized to find their targets for elimination. Therefore, personalized treatments enabled by CRISPR technology for chronic diseases such as cancer drive the CRISPR and Cas gene market growth. In addition, factors such as investments by biotech companies in new treatments; increased genomic research and development; and the rising burden of cancer, bloodborne diseases, and so on are facilitating the expansion of the market.
The factors driving the growth of the CRISPR and Cas gene market include the increasing prevalence of cancer and genetic diseases, and the burgeoning adoption of CRISPR-based screens with improved genomic targets.
The List of Companies - CRISPR and Cas Gene Market
- CRISPR Therapeutics
- BRAIN Biotech AG
- Thermo Fisher Scientific
- Merck KGaA
- Editas Medicine
- Takara Bio
- Genscript
- Qiagen
- New England Biolabs
- Intellia Therapeutics
The Insight Partners performs research in 4 major stages: Data Collection & Secondary Research, Primary Research, Data Analysis and Data Triangulation & Final Review.
- Data Collection and Secondary Research:
As a market research and consulting firm operating from a decade, we have published many reports and advised several clients across the globe. First step for any study will start with an assessment of currently available data and insights from existing reports. Further, historical and current market information is collected from Investor Presentations, Annual Reports, SEC Filings, etc., and other information related to company’s performance and market positioning are gathered from Paid Databases (Factiva, Hoovers, and Reuters) and various other publications available in public domain.
Several associations trade associates, technical forums, institutes, societies and organizations are accessed to gain technical as well as market related insights through their publications such as research papers, blogs and press releases related to the studies are referred to get cues about the market. Further, white papers, journals, magazines, and other news articles published in the last 3 years are scrutinized and analyzed to understand the current market trends.
- Primary Research:
The primarily interview analysis comprise of data obtained from industry participants interview and answers to survey questions gathered by in-house primary team.
For primary research, interviews are conducted with industry experts/CEOs/Marketing Managers/Sales Managers/VPs/Subject Matter Experts from both demand and supply side to get a 360-degree view of the market. The primary team conducts several interviews based on the complexity of the markets to understand the various market trends and dynamics which makes research more credible and precise.
A typical research interview fulfils the following functions:
- Provides first-hand information on the market size, market trends, growth trends, competitive landscape, and outlook
- Validates and strengthens in-house secondary research findings
- Develops the analysis team’s expertise and market understanding
Primary research involves email interactions and telephone interviews for each market, category, segment, and sub-segment across geographies. The participants who typically take part in such a process include, but are not limited to:
- Industry participants: VPs, business development managers, market intelligence managers and national sales managers
- Outside experts: Valuation experts, research analysts and key opinion leaders specializing in the electronics and semiconductor industry.
Below is the breakup of our primary respondents by company, designation, and region:
Once we receive the confirmation from primary research sources or primary respondents, we finalize the base year market estimation and forecast the data as per the macroeconomic and microeconomic factors assessed during data collection.
- Data Analysis:
Once data is validated through both secondary as well as primary respondents, we finalize the market estimations by hypothesis formulation and factor analysis at regional and country level.
- 3.1 Macro-Economic Factor Analysis:
We analyse macroeconomic indicators such the gross domestic product (GDP), increase in the demand for goods and services across industries, technological advancement, regional economic growth, governmental policies, the influence of COVID-19, PEST analysis, and other aspects. This analysis aids in setting benchmarks for various nations/regions and approximating market splits. Additionally, the general trend of the aforementioned components aid in determining the market's development possibilities.
- 3.2 Country Level Data:
Various factors that are especially aligned to the country are taken into account to determine the market size for a certain area and country, including the presence of vendors, such as headquarters and offices, the country's GDP, demand patterns, and industry growth. To comprehend the market dynamics for the nation, a number of growth variables, inhibitors, application areas, and current market trends are researched. The aforementioned elements aid in determining the country's overall market's growth potential.
- 3.3 Company Profile:
The “Table of Contents” is formulated by listing and analyzing more than 25 - 30 companies operating in the market ecosystem across geographies. However, we profile only 10 companies as a standard practice in our syndicate reports. These 10 companies comprise leading, emerging, and regional players. Nonetheless, our analysis is not restricted to the 10 listed companies, we also analyze other companies present in the market to develop a holistic view and understand the prevailing trends. The “Company Profiles” section in the report covers key facts, business description, products & services, financial information, SWOT analysis, and key developments. The financial information presented is extracted from the annual reports and official documents of the publicly listed companies. Upon collecting the information for the sections of respective companies, we verify them via various primary sources and then compile the data in respective company profiles. The company level information helps us in deriving the base number as well as in forecasting the market size.
- 3.4 Developing Base Number:
Aggregation of sales statistics (2020-2022) and macro-economic factor, and other secondary and primary research insights are utilized to arrive at base number and related market shares for 2022. The data gaps are identified in this step and relevant market data is analyzed, collected from paid primary interviews or databases. On finalizing the base year market size, forecasts are developed on the basis of macro-economic, industry and market growth factors and company level analysis.
- Data Triangulation and Final Review:
The market findings and base year market size calculations are validated from supply as well as demand side. Demand side validations are based on macro-economic factor analysis and benchmarks for respective regions and countries. In case of supply side validations, revenues of major companies are estimated (in case not available) based on industry benchmark, approximate number of employees, product portfolio, and primary interviews revenues are gathered. Further revenue from target product/service segment is assessed to avoid overshooting of market statistics. In case of heavy deviations between supply and demand side values, all thes steps are repeated to achieve synchronization.
We follow an iterative model, wherein we share our research findings with Subject Matter Experts (SME’s) and Key Opinion Leaders (KOLs) until consensus view of the market is not formulated – this model negates any drastic deviation in the opinions of experts. Only validated and universally acceptable research findings are quoted in our reports.
We have important check points that we use to validate our research findings – which we call – data triangulation, where we validate the information, we generate from secondary sources with primary interviews and then we re-validate with our internal data bases and Subject matter experts. This comprehensive model enables us to deliver high quality, reliable data in shortest possible time.
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